A comparative study of the HPLC-MS profiles and biological efficiency of different solvent leaf extracts of two African plants: Bersama abyssinica and Scoparia dulcis

Kouadio Ibrahime Sinan, Kouadio Bene, Gokhan Zengin, Alina Diuzheva, J. Jekó́, Zoltán Cziáky, Carene Marie Nancy Picot-Allain, Adriano Mollica, Kannan Rr Rengasamy, Mohamad Fawzi Mahomoodally

Research output: Contribution to journalArticle

Abstract

In the present study, two medicinal plants from Africa, namely Bersama abyssinica Fresen. and Scoparia dulcis L., were extracted using ethyl acetate, methanol, and water. The antioxidant, enzyme (α-amylase, α-glucosidase, acetyl- and butyrylcholinesterase, lipase, and tyrosinase) inhibitory action, and phytochemical profiles of extracts of Bersama abyssinica and Scoparia dulcis were determined. The aqueous (180.62 and 61.81 mg gallic acid equivalent/g extract, for B. abyssinica and S. dulcis respectively) and methanol (75.21 and 57.81 mg rutin equivalent/g extract, for B. abyssinica and S. dulcis, respectively) extracts contained high concentrations of phenolic and flavonoids, respectively. The ethyl acetate extracts of both plants were potent inhibitors of α-glucosidase and tyrosinase. Several phytochemical groups were determined by HPLC-MS/MS. The study tend to suggest that B. abyssinica and S. dulcis are potential candidates for the development of novel therapeutical agents.

Original languageEnglish
JournalInternational Journal of Environmental Health Research
DOIs
Publication statusAccepted/In press - Jan 1 2019

Fingerprint

Scoparia
Methanol
High Pressure Liquid Chromatography
Flavonoids
Amylases
Glucosidases
Lipases
Antioxidants
Monophenol Monooxygenase
Phytochemicals
Enzymes
Acids
Butyrylcholinesterase
Rutin
Gallic Acid
Plant Extracts
Water
Acetylcholinesterase
Medicinal Plants
Lipase

Keywords

  • Africa
  • natural agents
  • phyto-compounds
  • therapeutics

ASJC Scopus subject areas

  • Pollution
  • Public Health, Environmental and Occupational Health
  • Health, Toxicology and Mutagenesis

Cite this

A comparative study of the HPLC-MS profiles and biological efficiency of different solvent leaf extracts of two African plants : Bersama abyssinica and Scoparia dulcis. / Sinan, Kouadio Ibrahime; Bene, Kouadio; Zengin, Gokhan; Diuzheva, Alina; Jekó́, J.; Cziáky, Zoltán; Picot-Allain, Carene Marie Nancy; Mollica, Adriano; Rengasamy, Kannan Rr; Mahomoodally, Mohamad Fawzi.

In: International Journal of Environmental Health Research, 01.01.2019.

Research output: Contribution to journalArticle

Sinan, Kouadio Ibrahime ; Bene, Kouadio ; Zengin, Gokhan ; Diuzheva, Alina ; Jekó́, J. ; Cziáky, Zoltán ; Picot-Allain, Carene Marie Nancy ; Mollica, Adriano ; Rengasamy, Kannan Rr ; Mahomoodally, Mohamad Fawzi. / A comparative study of the HPLC-MS profiles and biological efficiency of different solvent leaf extracts of two African plants : Bersama abyssinica and Scoparia dulcis. In: International Journal of Environmental Health Research. 2019.
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