A changing pattern in the association of oral contraceptives and the different groups of congenital limb deficiencies

Andrew E. Czeizel, Imre Kodaj

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

A case-control study on different groups of isolated congenital limb deficiency was performed in a ten-year population-based and revised Hungarian data set. A higher rate of one contraceptive pill type with relatively high dose (ethynodiol diacetate 1.0 mg + ethinyloestradiol 0.05 mg) used in the periconceptional period was found in the mothers of cases with terminal transverse defect (adjusted relative odds 1.9 with 95% confidence interval of 1.1-3.4). This risk is minimised by the use of recent low-dose pills.

Original languageEnglish
Pages (from-to)19-24
Number of pages6
JournalContraception
Volume51
Issue number1
DOIs
Publication statusPublished - Jan 1995

Keywords

  • congenital limb deficiency
  • contraceptive pills
  • terminal transverse defects

ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynaecology

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