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Author

  • B. Penke
2012

A novel method for the rapid determination of beta-amyloid toxicity on acute hippocampal slices using MTT and LDH assays

Mozes, E., Hunya, A., Posa, A., Penke, B. & Datki, Z., Apr 10 2012, In : Brain Research Bulletin. 87, 6, p. 521-525 5 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)
2018

The role of sigma-1 receptor, an intracellular chaperone in neurodegenerative diseases

Penke, B., Fülöp, L., Szűcs, M. & Frecska, E., Jan 1 2018, In : Current neuropharmacology. 16, 1, p. 97-116 20 p.

Research output: Contribution to journalReview article

23 Citations (Scopus)
2013

Proteome-wide study of endoplasmic reticulum stress induced by thapsigargin in N2a neuroblastoma cells

Földi, I., Tóth, A. M., Szabó, Z., Mózes, E., Berkecz, R., Datki, Z. L., Penke, B. & Janáky, T., Jan 1 2013, In : Neurochemistry international. 62, 1, p. 58-69 12 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)
2015
12 Citations (Scopus)
2014
13 Citations (Scopus)
2017

Studies for improving a rat model of Alzheimer's disease: ICV administration of well-characterized β-amyloid 1-42 oligomers induce dysfunction in spatial memory

Kasza, Á., Penke, B., Frank, Z., Bozsó, Z., Szegedi, V., Hunya, Á., Németh, K., Kozma, G. & Fülöp, L., Nov 2017, In : Molecules. 22, 11, 2007.

Research output: Contribution to journalArticle

17 Citations (Scopus)
2014

Abeta(1-42) enhances neuronal excitability in the CA1 via NR2B subunit-containing NMDA receptors

Varga, E., Juhász, G., Bozsó, Z., Penke, B., Fülöp, L. & Szegedi, V., 2014, In : Neural Plasticity. 2014, 584314.

Research output: Contribution to journalArticle

13 Citations (Scopus)
2012

Intraneuronal β-amyloid and its interactions with proteins and subcellular organelles

Penke, B., Tóth, A. M., Földi, I., Szucs, M. & Janáky, T., Dec 1 2012, In : ELECTROPHORESIS. 33, 24, p. 3608-3616 9 p.

Research output: Contribution to journalReview article

22 Citations (Scopus)
2013

Penetratin and derivatives acting as antibacterial agents

Garro, A. D., Olivella, M. S., Bombasaro, J. A., Lima, B., Tapia, A., Feresin, G., Perczel, A., Somlai, C., Penke, B., López Cascales, J., Rodríguez, A. M. & Enriz, R. D., Aug 1 2013, In : Chemical Biology and Drug Design. 82, 2, p. 167-177 11 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Epitaxial assembly dynamics of mutant amyloid β25-35-N27C fibrils explored with time-resolved scanning force microscopy

Kellermayer, M. S. Z., Murvai, Ü., Horváth, A., Lászlóffi, E., Soós, K. & Penke, B., Jan 1 2013, In : Biophysical Chemistry. 184, p. 54-61 8 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2016

Dihydropyridine Derivatives Modulate Heat Shock Responses and have a Neuroprotective Effect in a Transgenic Mouse Model of Alzheimer's Disease

Kasza, Á., Hunya, Á., Frank, Z., Fülöp, F., Török, Z., Balogh, G., Sántha, M., Bálind, Á., Bernáth, S., Blundell, K. L. I. M., Prodromou, C., Horváth, I., Zeiler, H. J., Hooper, P. L., Vigh, L., Penke, B. & Abisambra, J., 2016, In : Journal of Alzheimer's Disease. 53, 2, p. 557-571 15 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)
2012

TLR2 is a primary receptor for Alzheimer's amyloid β peptide to trigger neuroinflammatory activation

Liu, S., Liu, Y., Hao, W., Wolf, L., Kiliaan, A. J., Penke, B., Rübe, C. E., Walter, J., Heneka, M. T., Hartmann, T., Menger, M. D. & Fassbender, K., Feb 1 2012, In : Journal of Immunology. 188, 3, p. 1098-1107 10 p.

Research output: Contribution to journalArticle

193 Citations (Scopus)

Conformational dynamics of titin PEVK explored with FRET spectroscopy

Huber, T., Grama, L., Hetényi, C., Schay, G., Fülöp, L., Penke, B. & Kellermayer, M. S. Z., Oct 3 2012, In : Biophysical journal. 103, 7, p. 1480-1489 10 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
2018

The role of lipids and membranes in the pathogenesis of alzheimer's disease: A comprehensive view

Penke, B., Paragi, G., Gera, J., Berkecz, R., Kovács, Z., Crul, T. & Vígh, L., Jan 1 2018, In : Current Alzheimer Research. 15, 13, p. 1191-1212 22 p.

Research output: Contribution to journalReview article

17 Citations (Scopus)
2014

Highly immunoreactive IgG antibodies directed against a set of twenty human proteins in the sera of patients with amyotrophic lateral sclerosis identified by protein array

May, C., Nordhoff, E., Casjens, S., Turewicz, M., Eisenacher, M., Gold, R., Brüning, T., Pesch, B., Stephan, C., Woitalla, D., Penke, B., Janáky, T., Virók, D., Siklós, L., Engelhardt, J. I. & Meyer, H. E., Feb 26 2014, In : PloS one. 9, 2, e89596.

Research output: Contribution to journalArticle

20 Citations (Scopus)
2015

Opposite effect of Ca2+/Mg2+ ions on the aggregation of native and precursor-derived Aβ42

Bogár, F., Simon, D., Bozsó, Z., Janáky, T., Veszelka, S., Tóth, A. E., Deli, M. A., Borics, A., Násztor, Z., Gyebrovszki, A., Penke, B. & Fülöp, L., Dec 1 2015, In : Structural Chemistry. 26, 5-6, p. 1389-1403 15 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2014

Special lipid-based diets alleviate cognitive deficits in the APPswe/PS1dE9 transgenic mouse model of Alzheimer's disease independent of brain amyloid deposition

Koivisto, H., Grimm, M. O., Rothhaar, T. L., Berkecz, R., Lütjohann D, D., Giniatullina, R., Takalo, M., Miettinen, P. O., Lahtinen, H. M., Giniatullin, R., Penke, B., Janáky, T., Broersen, L. M., Hartmann, T. & Tanila, H., Feb 1 2014, In : Journal of Nutritional Biochemistry. 25, 2, p. 157-169 13 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)
2018
18 Citations (Scopus)
2019

Key peptides and proteins in alzheimer’s disease

Penke, B., Bogár, F., Paragi, G., Gera, J. & Fülöp, L., Jan 1 2019, In : Current Protein and Peptide Science. 20, 6, p. 577-599 23 p.

Research output: Contribution to journalReview article

6 Citations (Scopus)
2013

Docosahexaenoic acid reduces amyloid-β induced toxicity in cells of the neurovascular unit

Veszelka, S., Tóth, A. E., Walter, F. R., Datki, Z., Mózes, E., Fülöp, L., Bozsó, Z., Hellinger, É., Vastag, M., Orsolits, B., Környei, Z., Penke, B. & Deli, M. A., 2013, In : Journal of Alzheimer's Disease. 36, 3, p. 487-501 15 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Overexpression of Hsp27 ameliorates symptoms of Alzheimer's disease in APP/PS1 mice

Tóth, M. E., Szegedi, V., Varga, E., Juhász, G., Horváth, J., Borbély, E., Csibrány, B., Alföldi, R., Lénárt, N., Penke, B. & Sántha, M., Apr 22 2013, In : Cell Stress and Chaperones. 18, 6, p. 759-771 13 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)
2019

Effects of the pentapeptide p33 on memory and synaptic plasticity in app/ps1 transgenic mice: a novel mechanism presenting the protein fe65 as a target

Szögi, T., Schuster, I., Borbély, E., Gyebrovszki, A., Bozsó, Z., Gera, J., Rajkó, R., Sántha, M., Penke, B. & Fülöp, L., Jun 2 2019, In : International journal of molecular sciences. 20, 12, 3050.

Research output: Contribution to journalArticle

Open Access
2012

GluA1 phosphorylation alters evoked firing pattern in vivo

Barkczi, B., Juhász, G., Averkin, R. G., Vrs, I., Vertes, P., Penke, B. & Szegedi, V., Jan 1 2012, In : Neural Plasticity. 2012, 286215.

Research output: Contribution to journalArticle

7 Citations (Scopus)
2017

β-amyloid and the pathomechanisms of Alzheimer’s disease: A comprehensive view

Penke, B., Bogár, F. & Fülöp, L., Oct 2017, In : Molecules. 22, 10, 1692.

Research output: Contribution to journalReview article

33 Citations (Scopus)
2020
Open Access
2012

Synthesis and cytotoxic activity of 4-N-carboxybutyl-5-fluorocytosyl-Arg- Gln-Trp-Arg-Arg-Trp-Trp-Gln-Arg-NH 2

Somlai, C., Correche, E., Olivella, M., Tolosa, L., Lechon, M. J. G., Dombi, G., Tóth, G. K., Penke, B. & Enriz, R. D., Jul 1 2012, In : Bioorganic and Medicinal Chemistry Letters. 22, 13, p. 4233-4237 5 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2015
5 Citations (Scopus)
2013

Tenascin-C deficiency ameliorates alzheimer's disease-related pathology in mice

Xie, K., Liu, Y., Hao, W., Walter, S., Penke, B., Hartmann, T., Schachner, M. & Fassbender, K., Oct 1 2013, In : Neurobiology of Aging. 34, 10, p. 2389-2398 10 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)
2017

New small-size peptides modulators of the exosite of BACE1 obtained from a structure-based design

Gutierrez, L. J., Angelina, E., Gyebrovszki, A., Fülöp, L., Peruchena, N., Baldoni, H. A., Penke, B. & Enriz, R. D., Jan 25 2017, In : Journal of Biomolecular Structure and Dynamics. 35, 2, p. 413-426 14 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
2016
21 Citations (Scopus)
2012

Increased Tau Phosphorylation and Impaired Presynaptic Function in Hypertriglyceridemic ApoB-100 Transgenic Mice

Lénárt, N., Szegedi, V., Juhász, G., Kasztner, A., Horváth, J., Bereczki, E., Tóth, M. E., Penke, B. & Sántha, M., Sep 24 2012, In : PloS one. 7, 9, e46007.

Research output: Contribution to journalArticle

12 Citations (Scopus)
2018

Cerebrovascular pathology in hypertriglyceridemic APOB-100 transgenic mice

Hoyk, Z., Tóth, M. E., Lénárt, N., Nagy, D., Dukay, B., Csefová, A., Zvara, Á., Seprényi, G., Kincses, A., Walter, F. R., Veszelka, S., Vígh, J., Barabási, B., Harazin, A., Kittel, Á., Puskás, L. G., Penke, B., Vígh, L., Deli, M. & Sántha, M., Oct 25 2018, In : Frontiers in Cellular Neuroscience. 12, 380.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2017

Mitochondrial Proteome Changes Correlating with β-Amyloid Accumulation

Völgyi, K., Háden, K., Kis, V., Gulyássy, P., Badics, K., Györffy, B. A., Simor, A., Szabó, Z., Janáky, T., Drahos, L., Dobolyi, Á., Penke, B., Juhász, G. & Kékesi, K. A., Apr 1 2017, In : Molecular Neurobiology. 54, 3, p. 2060-2078 19 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
2015
39 Citations (Scopus)
2012

Altered Functional Protein Networks in the Prefrontal Cortex and Amygdala of Victims of Suicide

Kékesi, K. A., Juhász, G., Simor, A., Gulyássy, P., Szego, É. M., Hunyadi-Gulyás, É., Darula, Z., Medzihradszky, K. F., Palkovits, M., Penke, B. & Czurkó, A., Dec 6 2012, In : PloS one. 7, 12, e50532.

Research output: Contribution to journalArticle

39 Citations (Scopus)
2015

Amyloid-β1-42 Disrupts Synaptic Plasticity by Altering Glutamate Recycling at the Synapse

Varga, E., Juhász, G., Bozsó, Z., Penke, B., Fülöp, L. & Szegedi, V., 2015, In : Journal of Alzheimer's Disease. 45, 2, p. 449-456 8 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)