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  • B. Penke
2011

Exploring and characterizing the folding processes of Lys- and Arg-containing Ala-based peptides: A molecular dynamics study

Janzsó, G., Bogár, F., Hudoba, L., Penke, B., Rákhely, G. & Leitgeb, B., Aug 10 2011, In : Computational Biology and Chemistry. 35, 4, p. 240-250 11 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Docosahexaenoic acid reduces amyloid β production via multiple pleiotropic mechanisms

Grimm, M. O. W., Kuchenbecker, J., Grosgen, S., Burg, V. K., Hundsdorfer, B., Rothhaar, T. L., Friess, P., De Wilde, M. C., Broersen, L. M., Penke, B., Peter, M., Vígh, L., Grimm, H. S. & Hartmann, T., Apr 22 2011, In : Journal of Biological Chemistry. 286, 16, p. 14028-14039 12 p.

Research output: Contribution to journalArticle

124 Citations (Scopus)

A novel application of the fluorescent dye bis-ANS for labeling neurons in acute brain slices

Mozes, E., Hunya, A., Toth, A., Ayaydin, F., Penke, B. & Datki, Z. L., Oct 10 2011, In : Brain Research Bulletin. 86, 3-4, p. 217-221 5 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Neutral and positively charged new purine tetramer structures: A computational study of xanthine and uric acid derivatives

Paragi, G., Kovács, L., Kupihár, Z., Szolomájer, J., Penke, B., Fonseca Guerra, C. & Bickelhaupt, F. M., Jan 2011, In : New Journal of Chemistry. 35, 1, p. 119-126 8 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Characterisation of the variation of mouse brain proteome by two-dimensional electrophoresis

Földi, I., Müller, G., Penke, B. & Janáky, T., May 16 2011, In : Journal of proteomics. 74, 6, p. 894-901 8 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Penetratin analogues acting as antifungal agents

Garibotto, F. M., Garro, A. D., Rodríguez, A. M., Raimondi, M., Zacchino, S. A., Perczel, A., Somlai, C., Penke, B. & Enriz, R. D., Jan 2011, In : European Journal of Medicinal Chemistry. 46, 1, p. 370-377 8 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
2013

Proteome-wide study of endoplasmic reticulum stress induced by thapsigargin in N2a neuroblastoma cells

Földi, I., Tóth, A. M., Szabó, Z., Mózes, E., Berkecz, R., Datki, Z. L., Penke, B. & Janáky, T., Jan 1 2013, In : Neurochemistry international. 62, 1, p. 58-69 12 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)
2011

Effects of estrogen on beta-amyloid-induced cholinergic cell death in the nucleus basalis magnocellularis

Szego, É. M., Csorba, A., Janáky, T., Kékesi, K. A., Ábrahám, I. M., Mórotz, G. M., Penke, B., Palkovits, M., Murvai, Ü., Kellermayer, M. S. Z., Kardos, J. & Juhász, G. D., Mar 1 2011, In : Neuroendocrinology. 93, 2, p. 90-105 16 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)
2014
13 Citations (Scopus)

Abeta(1-42) enhances neuronal excitability in the CA1 via NR2B subunit-containing NMDA receptors

Varga, E., Juhász, G., Bozsó, Z., Penke, B., Fülöp, L. & Szegedi, V., 2014, In : Neural Plasticity. 2014, 584314.

Research output: Contribution to journalArticle

13 Citations (Scopus)
2015
12 Citations (Scopus)
2018

The role of sigma-1 receptor, an intracellular chaperone in neurodegenerative diseases

Penke, B., Fülöp, L., Szűcs, M. & Frecska, E., Jan 1 2018, In : Current neuropharmacology. 16, 1, p. 97-116 20 p.

Research output: Contribution to journalReview article

23 Citations (Scopus)
2011
6 Citations (Scopus)
2017

Studies for improving a rat model of Alzheimer's disease: ICV administration of well-characterized β-amyloid 1-42 oligomers induce dysfunction in spatial memory

Kasza, Á., Penke, B., Frank, Z., Bozsó, Z., Szegedi, V., Hunya, Á., Németh, K., Kozma, G. & Fülöp, L., Nov 2017, In : Molecules. 22, 11, 2007.

Research output: Contribution to journalArticle

17 Citations (Scopus)
2013

Epitaxial assembly dynamics of mutant amyloid β25-35-N27C fibrils explored with time-resolved scanning force microscopy

Kellermayer, M. S. Z., Murvai, Ü., Horváth, A., Lászlóffi, E., Soós, K. & Penke, B., Jan 1 2013, In : Biophysical Chemistry. 184, p. 54-61 8 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2011

Helix and H-bond formations of alanine-based peptides containing basic amino acids

Leitgeb, B., Janzsó, G., Hudoba, L., Penke, B., Rákhely, G. & Bogár, F., Dec 1 2011, In : Structural Chemistry. 22, 6, p. 1287-1295 9 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2013

Penetratin and derivatives acting as antibacterial agents

Garro, A. D., Olivella, M. S., Bombasaro, J. A., Lima, B., Tapia, A., Feresin, G., Perczel, A., Somlai, C., Penke, B., López Cascales, J., Rodríguez, A. M. & Enriz, R. D., Aug 1 2013, In : Chemical Biology and Drug Design. 82, 2, p. 167-177 11 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2016

Dihydropyridine Derivatives Modulate Heat Shock Responses and have a Neuroprotective Effect in a Transgenic Mouse Model of Alzheimer's Disease

Kasza, Á., Hunya, Á., Frank, Z., Fülöp, F., Török, Z., Balogh, G., Sántha, M., Bálind, Á., Bernáth, S., Blundell, K. L. I. M., Prodromou, C., Horváth, I., Zeiler, H. J., Hooper, P. L., Vigh, L., Penke, B. & Abisambra, J., 2016, In : Journal of Alzheimer's Disease. 53, 2, p. 557-571 15 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)
2014

Highly immunoreactive IgG antibodies directed against a set of twenty human proteins in the sera of patients with amyotrophic lateral sclerosis identified by protein array

May, C., Nordhoff, E., Casjens, S., Turewicz, M., Eisenacher, M., Gold, R., Brüning, T., Pesch, B., Stephan, C., Woitalla, D., Penke, B., Janáky, T., Virók, D., Siklós, L., Engelhardt, J. I. & Meyer, H. E., Feb 26 2014, In : PloS one. 9, 2, e89596.

Research output: Contribution to journalArticle

20 Citations (Scopus)
2011

Protein array based interactome analysis of amyloid-β indicates an inhibition of protein translation

Virok, D. P., Simon, D., Bozsó, Z., Rajkó, R., Datki, Z., Bálint, É., Szegedi, V., Janáky, T., Penke, B. & Fülöp, L., Apr 1 2011, In : Journal of Proteome Research. 10, 4, p. 1538-1547 10 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)
2015

Opposite effect of Ca2+/Mg2+ ions on the aggregation of native and precursor-derived Aβ42

Bogár, F., Simon, D., Bozsó, Z., Janáky, T., Veszelka, S., Tóth, A. E., Deli, M. A., Borics, A., Násztor, Z., Gyebrovszki, A., Penke, B. & Fülöp, L., Dec 1 2015, In : Structural Chemistry. 26, 5-6, p. 1389-1403 15 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2019

Key peptides and proteins in alzheimer’s disease

Penke, B., Bogár, F., Paragi, G., Gera, J. & Fülöp, L., Jan 1 2019, In : Current Protein and Peptide Science. 20, 6, p. 577-599 23 p.

Research output: Contribution to journalReview article

6 Citations (Scopus)
2013

Overexpression of Hsp27 ameliorates symptoms of Alzheimer's disease in APP/PS1 mice

Tóth, M. E., Szegedi, V., Varga, E., Juhász, G., Horváth, J., Borbély, E., Csibrány, B., Alföldi, R., Lénárt, N., Penke, B. & Sántha, M., Apr 22 2013, In : Cell Stress and Chaperones. 18, 6, p. 759-771 13 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)

Docosahexaenoic acid reduces amyloid-β induced toxicity in cells of the neurovascular unit

Veszelka, S., Tóth, A. E., Walter, F. R., Datki, Z., Mózes, E., Fülöp, L., Bozsó, Z., Hellinger, É., Vastag, M., Orsolits, B., Környei, Z., Penke, B. & Deli, M. A., 2013, In : Journal of Alzheimer's Disease. 36, 3, p. 487-501 15 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)
2019

Effects of the pentapeptide p33 on memory and synaptic plasticity in app/ps1 transgenic mice: a novel mechanism presenting the protein fe65 as a target

Szögi, T., Schuster, I., Borbély, E., Gyebrovszki, A., Bozsó, Z., Gera, J., Rajkó, R., Sántha, M., Penke, B. & Fülöp, L., Jun 2 2019, In : International journal of molecular sciences. 20, 12, 3050.

Research output: Contribution to journalArticle

Open Access
2018
18 Citations (Scopus)

The role of lipids and membranes in the pathogenesis of alzheimer's disease: A comprehensive view

Penke, B., Paragi, G., Gera, J., Berkecz, R., Kovács, Z., Crul, T. & Vígh, L., Jan 1 2018, In : Current Alzheimer Research. 15, 13, p. 1191-1212 22 p.

Research output: Contribution to journalReview article

17 Citations (Scopus)
2014

Special lipid-based diets alleviate cognitive deficits in the APPswe/PS1dE9 transgenic mouse model of Alzheimer's disease independent of brain amyloid deposition

Koivisto, H., Grimm, M. O., Rothhaar, T. L., Berkecz, R., Lütjohann D, D., Giniatullina, R., Takalo, M., Miettinen, P. O., Lahtinen, H. M., Giniatullin, R., Penke, B., Janáky, T., Broersen, L. M., Hartmann, T. & Tanila, H., Feb 1 2014, In : Journal of Nutritional Biochemistry. 25, 2, p. 157-169 13 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)
2011

Tianeptine potentiates AMPA receptors by activating CaMKII and PKA via the p38, p42/44 MAPK and JNK pathways

Szegedi, V., Juhász, G., Zhang, X., Barkóczi, B., Qi, H., Madeira, A., Kapus, G., Svenningsson, P., Spedding, M. & Penke, B., Dec 1 2011, In : Neurochemistry international. 59, 8, p. 1109-1122 14 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)
2017

β-amyloid and the pathomechanisms of Alzheimer’s disease: A comprehensive view

Penke, B., Bogár, F. & Fülöp, L., Oct 2017, In : Molecules. 22, 10, 1692.

Research output: Contribution to journalReview article

33 Citations (Scopus)
2020
Open Access
2011

Effect of the beta-sheet-breaker peptide LPFFD on oriented network of amyloid β25-35 fibrils

Murvai, Ü., Soós, K., Penke, B. & Kellermayer, M. S. Z., May 1 2011, In : Journal of Molecular Recognition. 24, 3, p. 453-460 8 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
2015
5 Citations (Scopus)
2011

Myeloid differentiation factor 88-deficient bone marrow cells improve Alzheimer's disease-related symptoms and pathology

Hao, W., Liu, Y., Liu, S., Walter, S., Grimm, M. O., Kiliaan, A. J., Penke, B., Hartmann, T., Rübe, C. E., Menger, M. D. & Fassbender, K., Jan 2011, In : Brain. 134, 1, p. 278-292 15 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Neuroprotective effects of a specific multi-nutrient intervention against Aβ42-induced toxicity in rats

De Wilde, M. C., Penke, B., Van Der Beek, E. M., Kuipers, A. A. M., Kamphuis, P. J. & Broersen, L. M., 2011, In : Journal of Alzheimer's Disease. 27, 2, p. 327-339 13 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)

New small-size antifungal peptides: Design, synthesis and antifungal activity

Garro, A. D., Garibotto, F. M., Rodriguez, A. M., Raimondi, M., Zacchino, S. A., Perczel, A., Somlai, C., Penke, B. & Enriz, R. D., Jul 2011, In : Letters in Drug Design and Discovery. 8, 6, p. 562-567 6 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Proteomic study of the toxic effect of oligomeric Aβ1-42 in situ prepared from 'iso-Aβ1-42'

Földi, I., Datki, Z. L., Szabõ, Z., Bozsõ, Z., Penke, B. & Janáky, T., May 1 2011, In : Journal of neurochemistry. 117, 4, p. 691-702 12 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)
2013

Tenascin-C deficiency ameliorates alzheimer's disease-related pathology in mice

Xie, K., Liu, Y., Hao, W., Walter, S., Penke, B., Hartmann, T., Schachner, M. & Fassbender, K., Oct 1 2013, In : Neurobiology of Aging. 34, 10, p. 2389-2398 10 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)
2017

New small-size peptides modulators of the exosite of BACE1 obtained from a structure-based design

Gutierrez, L. J., Angelina, E., Gyebrovszki, A., Fülöp, L., Peruchena, N., Baldoni, H. A., Penke, B. & Enriz, R. D., Jan 25 2017, In : Journal of Biomolecular Structure and Dynamics. 35, 2, p. 413-426 14 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
2016
21 Citations (Scopus)
2018

Cerebrovascular pathology in hypertriglyceridemic APOB-100 transgenic mice

Hoyk, Z., Tóth, M. E., Lénárt, N., Nagy, D., Dukay, B., Csefová, A., Zvara, Á., Seprényi, G., Kincses, A., Walter, F. R., Veszelka, S., Vígh, J., Barabási, B., Harazin, A., Kittel, Á., Puskás, L. G., Penke, B., Vígh, L., Deli, M. & Sántha, M., Oct 25 2018, In : Frontiers in Cellular Neuroscience. 12, 380.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2017

Mitochondrial Proteome Changes Correlating with β-Amyloid Accumulation

Völgyi, K., Háden, K., Kis, V., Gulyássy, P., Badics, K., Györffy, B. A., Simor, A., Szabó, Z., Janáky, T., Drahos, L., Dobolyi, Á., Penke, B., Juhász, G. & Kékesi, K. A., Apr 1 2017, In : Molecular Neurobiology. 54, 3, p. 2060-2078 19 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
2011

Systems biology of Alzheimer's disease: How diverse molecular changes result in memory impairment in AD

Juhász, G., Földi, I. & Penke, B., Jun 2011, In : Neurochemistry international. 58, 7, p. 739-750 12 p.

Research output: Contribution to journalShort survey

19 Citations (Scopus)
2015
39 Citations (Scopus)
2011

Interactions of pathological hallmark proteins: Tubulin polymerization promoting protein/p25,β-amyloid, and α-synuclein

Oláh, J., Vincze, O., Virók, D., Simon, D., Bozsó, Z., Tokési, N., Horváth, I., Hlavanda, E., Kovács, J., Magyar, A., Szucs, M., Orosz, F., Penke, B. & Ovádi, J., Oct 30 2011, In : Journal of Biological Chemistry. 286, 39, p. 34088-34100 13 p.

Research output: Contribution to journalArticle

72 Citations (Scopus)
2015

Amyloid-β1-42 Disrupts Synaptic Plasticity by Altering Glutamate Recycling at the Synapse

Varga, E., Juhász, G., Bozsó, Z., Penke, B., Fülöp, L. & Szegedi, V., 2015, In : Journal of Alzheimer's Disease. 45, 2, p. 449-456 8 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)