5-Hydroxytryptamine injected intraventricularly fails to influence the brain water content

T. Doczi, P. Szerdahelyi, F. Joo

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Measurement of the content of brain water and electrolytes after the intraventricular administration of 5-hydroxytryptamine in rats, with and without exposure to osmotic stress, failed to show water accumulation in the brain parenchyma. It is suggested that elevation of serotonin in the cerebrospinal fluid - resembling pathological situations such as subarachnoid hemorrhage - does not play a primary role in brain edema formation.

Original languageEnglish
Pages (from-to)165-169
Number of pages5
JournalNeurosurgery
Volume15
Issue number2
DOIs
Publication statusPublished - Jan 1 1984

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

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