24-hour efficacy of the bimatoprost-timolol fixed combination versus latanoprost as first choice therapy in subjects with high-pressure exfoliation syndrome and glaucoma

Anastasios Georgios P Konstas, G. Holló, Dimitrios G. Mikropoulos, Anna Bettina Haidich, Antonios T. Dimopoulos, Theodoros Empeslidis, Miguel A. Teus, Robert Ritch

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Aim: To compare the 24-h intraocular pressure (IOP) control obtained with the bimatoprost-timolol fixed combination (BTFC) versus latanoprost in newly diagnosed, previously untreated exfoliation syndrome (XFS) or exfoliative glaucoma (XFG) patients with baseline morning IOP greater than 29 mm Hg. Methods: One eye of 41 XFS/XFG patients who met inclusion criteria was included in this prospective, observer-masked, crossover, comparison protocol. All subjects underwent a 24-h untreated curve and were then randomised to either evening administered BTFC or latanoprost for 3 months and then switched to the opposite therapy. At the end of each treatment period, patients underwent a treated 24-h IOP assessment. Results: 37 patients completed the trial. At baseline, mean untreated 24-h IOP was 31.1 mm Hg. Mean 24-h IOP with BTFC was significantly lower than with latanoprost (18.9 vs 21.2 mm Hg; p

Original languageEnglish
Pages (from-to)857-861
Number of pages5
JournalBritish Journal of Ophthalmology
Volume97
Issue number7
DOIs
Publication statusPublished - Jul 2013

Fingerprint

latanoprost
Exfoliation Syndrome
Timolol
Intraocular Pressure
Pressure
Therapeutics
Glaucoma
Bimatoprost

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience

Cite this

24-hour efficacy of the bimatoprost-timolol fixed combination versus latanoprost as first choice therapy in subjects with high-pressure exfoliation syndrome and glaucoma. / Konstas, Anastasios Georgios P; Holló, G.; Mikropoulos, Dimitrios G.; Haidich, Anna Bettina; Dimopoulos, Antonios T.; Empeslidis, Theodoros; Teus, Miguel A.; Ritch, Robert.

In: British Journal of Ophthalmology, Vol. 97, No. 7, 07.2013, p. 857-861.

Research output: Contribution to journalArticle

Konstas, Anastasios Georgios P ; Holló, G. ; Mikropoulos, Dimitrios G. ; Haidich, Anna Bettina ; Dimopoulos, Antonios T. ; Empeslidis, Theodoros ; Teus, Miguel A. ; Ritch, Robert. / 24-hour efficacy of the bimatoprost-timolol fixed combination versus latanoprost as first choice therapy in subjects with high-pressure exfoliation syndrome and glaucoma. In: British Journal of Ophthalmology. 2013 ; Vol. 97, No. 7. pp. 857-861.
@article{6fda6cb8c63243d08d53cd225dba0f04,
title = "24-hour efficacy of the bimatoprost-timolol fixed combination versus latanoprost as first choice therapy in subjects with high-pressure exfoliation syndrome and glaucoma",
abstract = "Aim: To compare the 24-h intraocular pressure (IOP) control obtained with the bimatoprost-timolol fixed combination (BTFC) versus latanoprost in newly diagnosed, previously untreated exfoliation syndrome (XFS) or exfoliative glaucoma (XFG) patients with baseline morning IOP greater than 29 mm Hg. Methods: One eye of 41 XFS/XFG patients who met inclusion criteria was included in this prospective, observer-masked, crossover, comparison protocol. All subjects underwent a 24-h untreated curve and were then randomised to either evening administered BTFC or latanoprost for 3 months and then switched to the opposite therapy. At the end of each treatment period, patients underwent a treated 24-h IOP assessment. Results: 37 patients completed the trial. At baseline, mean untreated 24-h IOP was 31.1 mm Hg. Mean 24-h IOP with BTFC was significantly lower than with latanoprost (18.9 vs 21.2 mm Hg; p",
author = "Konstas, {Anastasios Georgios P} and G. Holl{\'o} and Mikropoulos, {Dimitrios G.} and Haidich, {Anna Bettina} and Dimopoulos, {Antonios T.} and Theodoros Empeslidis and Teus, {Miguel A.} and Robert Ritch",
year = "2013",
month = "7",
doi = "10.1136/bjophthalmol-2012-302843",
language = "English",
volume = "97",
pages = "857--861",
journal = "British Journal of Ophthalmology",
issn = "0007-1161",
publisher = "BMJ Publishing Group",
number = "7",

}

TY - JOUR

T1 - 24-hour efficacy of the bimatoprost-timolol fixed combination versus latanoprost as first choice therapy in subjects with high-pressure exfoliation syndrome and glaucoma

AU - Konstas, Anastasios Georgios P

AU - Holló, G.

AU - Mikropoulos, Dimitrios G.

AU - Haidich, Anna Bettina

AU - Dimopoulos, Antonios T.

AU - Empeslidis, Theodoros

AU - Teus, Miguel A.

AU - Ritch, Robert

PY - 2013/7

Y1 - 2013/7

N2 - Aim: To compare the 24-h intraocular pressure (IOP) control obtained with the bimatoprost-timolol fixed combination (BTFC) versus latanoprost in newly diagnosed, previously untreated exfoliation syndrome (XFS) or exfoliative glaucoma (XFG) patients with baseline morning IOP greater than 29 mm Hg. Methods: One eye of 41 XFS/XFG patients who met inclusion criteria was included in this prospective, observer-masked, crossover, comparison protocol. All subjects underwent a 24-h untreated curve and were then randomised to either evening administered BTFC or latanoprost for 3 months and then switched to the opposite therapy. At the end of each treatment period, patients underwent a treated 24-h IOP assessment. Results: 37 patients completed the trial. At baseline, mean untreated 24-h IOP was 31.1 mm Hg. Mean 24-h IOP with BTFC was significantly lower than with latanoprost (18.9 vs 21.2 mm Hg; p

AB - Aim: To compare the 24-h intraocular pressure (IOP) control obtained with the bimatoprost-timolol fixed combination (BTFC) versus latanoprost in newly diagnosed, previously untreated exfoliation syndrome (XFS) or exfoliative glaucoma (XFG) patients with baseline morning IOP greater than 29 mm Hg. Methods: One eye of 41 XFS/XFG patients who met inclusion criteria was included in this prospective, observer-masked, crossover, comparison protocol. All subjects underwent a 24-h untreated curve and were then randomised to either evening administered BTFC or latanoprost for 3 months and then switched to the opposite therapy. At the end of each treatment period, patients underwent a treated 24-h IOP assessment. Results: 37 patients completed the trial. At baseline, mean untreated 24-h IOP was 31.1 mm Hg. Mean 24-h IOP with BTFC was significantly lower than with latanoprost (18.9 vs 21.2 mm Hg; p

UR - http://www.scopus.com/inward/record.url?scp=84879418332&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84879418332&partnerID=8YFLogxK

U2 - 10.1136/bjophthalmol-2012-302843

DO - 10.1136/bjophthalmol-2012-302843

M3 - Article

C2 - 23686322

AN - SCOPUS:84879418332

VL - 97

SP - 857

EP - 861

JO - British Journal of Ophthalmology

JF - British Journal of Ophthalmology

SN - 0007-1161

IS - 7

ER -