2012 Provisional classification criteria for polymyalgia rheumatica: A European League Against Rheumatism/American College of Rheumatology collaborative initiative

Bhaskar Dasgupta, Marco A. Cimmino, Hilal Maradit-Kremers, Wolfgang A. Schmidt, Michael Schirmer, Carlo Salvarani, Artur Bachta, Christian Dejaco, Christina Duftner, Hanne Slott Jensen, Pierre Duhaut, G. Poór, Novák Pál Kaposi, Peter Mandl, P. Bálint, Zsuzsa Schmidt, Annamaria Iagnocco, Carlotta Nannini, Fabrizio Cantini, Pierluigi MacchioniNicolò Pipitone, Montserrat Del Amo, Georgina Espígol-Frigolé, Maria C. Cid, Víctor M. Martínez-Taboada, Elisabeth Nordborg, Haner Direskeneli, Sibel Zehra Aydin, Khalid Ahmed, Brian Hazleman, Barbara Silverman, Colin Pease, Richard J. Wakefield, Raashid Luqmani, Andy Abril, Clement J. Michet, Ralph Marcus, Neil J. Gonter, Mehrdad Maz, Rickey E. Carter, Cynthia S. Crowson, Eric L. Matteson

Research output: Contribution to journalArticle

200 Citations (Scopus)

Abstract

The objective of this study was to develop EULAR/ ACR classification criteria for polymyalgia rheumatica (PMR). Candidate criteria were evaluated in a 6-month prospective cohort study of 125 patients with new onset PMR and 169 non-PMR comparison subjects with conditions mimicking PMR. A scoring algorithm was developed based on morning stiffness >45 minutes (2 points), hip pain/limited range of motion (1 point), absence of RF and/or ACPA (2 points), and absence of peripheral joint pain (1 point). A score ≥4 had 68% sensitivity and 78% specificity for discriminating all comparison subjects from PMR. The specificity was higher (88%) for discriminating shoulder conditions from PMR and lower (65%) for discriminating RA from PMR. Adding ultrasound, a score ≥5 had increased sensitivity to 66% and specificity to 81%. According to these provisional classification criteria, patients ≥50 years old presenting with bilateral shoulder pain, not better explained by an alternative pathology, can be classified as having PMR in the presence of morning stiffness >45 minutes, elevated CRP and/or ESR and new hip pain. These criteria are not meant for diagnostic purposes.

Original languageEnglish
Pages (from-to)484-492
Number of pages9
JournalAnnals of the Rheumatic Diseases
Volume71
Issue number4
DOIs
Publication statusPublished - Apr 2012

Fingerprint

Polymyalgia Rheumatica
Stiffness
Pathology
Paramagnetic resonance
Ultrasonics
Hip
Pain
Shoulder Pain
Arthralgia
Articular Range of Motion
Cohort Studies
Prospective Studies
Sensitivity and Specificity
2-amino-3-(3-carboxy-5-methyl-4-isoxazolyl)propionic acid

ASJC Scopus subject areas

  • Rheumatology
  • Immunology
  • Biochemistry, Genetics and Molecular Biology(all)
  • Immunology and Allergy

Cite this

2012 Provisional classification criteria for polymyalgia rheumatica : A European League Against Rheumatism/American College of Rheumatology collaborative initiative. / Dasgupta, Bhaskar; Cimmino, Marco A.; Maradit-Kremers, Hilal; Schmidt, Wolfgang A.; Schirmer, Michael; Salvarani, Carlo; Bachta, Artur; Dejaco, Christian; Duftner, Christina; Jensen, Hanne Slott; Duhaut, Pierre; Poór, G.; Kaposi, Novák Pál; Mandl, Peter; Bálint, P.; Schmidt, Zsuzsa; Iagnocco, Annamaria; Nannini, Carlotta; Cantini, Fabrizio; Macchioni, Pierluigi; Pipitone, Nicolò; Del Amo, Montserrat; Espígol-Frigolé, Georgina; Cid, Maria C.; Martínez-Taboada, Víctor M.; Nordborg, Elisabeth; Direskeneli, Haner; Aydin, Sibel Zehra; Ahmed, Khalid; Hazleman, Brian; Silverman, Barbara; Pease, Colin; Wakefield, Richard J.; Luqmani, Raashid; Abril, Andy; Michet, Clement J.; Marcus, Ralph; Gonter, Neil J.; Maz, Mehrdad; Carter, Rickey E.; Crowson, Cynthia S.; Matteson, Eric L.

In: Annals of the Rheumatic Diseases, Vol. 71, No. 4, 04.2012, p. 484-492.

Research output: Contribution to journalArticle

Dasgupta, B, Cimmino, MA, Maradit-Kremers, H, Schmidt, WA, Schirmer, M, Salvarani, C, Bachta, A, Dejaco, C, Duftner, C, Jensen, HS, Duhaut, P, Poór, G, Kaposi, NP, Mandl, P, Bálint, P, Schmidt, Z, Iagnocco, A, Nannini, C, Cantini, F, Macchioni, P, Pipitone, N, Del Amo, M, Espígol-Frigolé, G, Cid, MC, Martínez-Taboada, VM, Nordborg, E, Direskeneli, H, Aydin, SZ, Ahmed, K, Hazleman, B, Silverman, B, Pease, C, Wakefield, RJ, Luqmani, R, Abril, A, Michet, CJ, Marcus, R, Gonter, NJ, Maz, M, Carter, RE, Crowson, CS & Matteson, EL 2012, '2012 Provisional classification criteria for polymyalgia rheumatica: A European League Against Rheumatism/American College of Rheumatology collaborative initiative', Annals of the Rheumatic Diseases, vol. 71, no. 4, pp. 484-492. https://doi.org/10.1136/annrheumdis-2011-200329
Dasgupta, Bhaskar ; Cimmino, Marco A. ; Maradit-Kremers, Hilal ; Schmidt, Wolfgang A. ; Schirmer, Michael ; Salvarani, Carlo ; Bachta, Artur ; Dejaco, Christian ; Duftner, Christina ; Jensen, Hanne Slott ; Duhaut, Pierre ; Poór, G. ; Kaposi, Novák Pál ; Mandl, Peter ; Bálint, P. ; Schmidt, Zsuzsa ; Iagnocco, Annamaria ; Nannini, Carlotta ; Cantini, Fabrizio ; Macchioni, Pierluigi ; Pipitone, Nicolò ; Del Amo, Montserrat ; Espígol-Frigolé, Georgina ; Cid, Maria C. ; Martínez-Taboada, Víctor M. ; Nordborg, Elisabeth ; Direskeneli, Haner ; Aydin, Sibel Zehra ; Ahmed, Khalid ; Hazleman, Brian ; Silverman, Barbara ; Pease, Colin ; Wakefield, Richard J. ; Luqmani, Raashid ; Abril, Andy ; Michet, Clement J. ; Marcus, Ralph ; Gonter, Neil J. ; Maz, Mehrdad ; Carter, Rickey E. ; Crowson, Cynthia S. ; Matteson, Eric L. / 2012 Provisional classification criteria for polymyalgia rheumatica : A European League Against Rheumatism/American College of Rheumatology collaborative initiative. In: Annals of the Rheumatic Diseases. 2012 ; Vol. 71, No. 4. pp. 484-492.
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AU - Schmidt, Wolfgang A.

AU - Schirmer, Michael

AU - Salvarani, Carlo

AU - Bachta, Artur

AU - Dejaco, Christian

AU - Duftner, Christina

AU - Jensen, Hanne Slott

AU - Duhaut, Pierre

AU - Poór, G.

AU - Kaposi, Novák Pál

AU - Mandl, Peter

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AU - Schmidt, Zsuzsa

AU - Iagnocco, Annamaria

AU - Nannini, Carlotta

AU - Cantini, Fabrizio

AU - Macchioni, Pierluigi

AU - Pipitone, Nicolò

AU - Del Amo, Montserrat

AU - Espígol-Frigolé, Georgina

AU - Cid, Maria C.

AU - Martínez-Taboada, Víctor M.

AU - Nordborg, Elisabeth

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AU - Aydin, Sibel Zehra

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AU - Pease, Colin

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AU - Abril, Andy

AU - Michet, Clement J.

AU - Marcus, Ralph

AU - Gonter, Neil J.

AU - Maz, Mehrdad

AU - Carter, Rickey E.

AU - Crowson, Cynthia S.

AU - Matteson, Eric L.

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