2 Primary prevention of birth defects by periconceptional care, including multivitamin supplementation

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Abstract

Periconceptional care can significantly reduce untoward pregnancy outcomes and birth defects. The avoidance of alcohol, rubella vaccination and special care for certain maternal disorders can prevent some CAs. Periconceptional multivitamin supplementation, including a physiological dose of folic acid, has been shown to reduce the occurrence of NTDs and some other major CAs. The preventable proportion of the latter group is three times higher than the incidence of NTDs. Thus, periconceptional care that includes such supplementation increases the proportion of preventable defects and improves the efficacy of primary prevention.

Original languageEnglish
Pages (from-to)417-430
Number of pages14
JournalBailliere's Clinical Obstetrics and Gynaecology
Volume9
Issue number3
DOIs
Publication statusPublished - 1995

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Rubella
Primary Prevention
Pregnancy Outcome
Folic Acid
Vaccination
Alcohols
Mothers
Incidence

ASJC Scopus subject areas

  • Obstetrics and Gynaecology

Cite this

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abstract = "Periconceptional care can significantly reduce untoward pregnancy outcomes and birth defects. The avoidance of alcohol, rubella vaccination and special care for certain maternal disorders can prevent some CAs. Periconceptional multivitamin supplementation, including a physiological dose of folic acid, has been shown to reduce the occurrence of NTDs and some other major CAs. The preventable proportion of the latter group is three times higher than the incidence of NTDs. Thus, periconceptional care that includes such supplementation increases the proportion of preventable defects and improves the efficacy of primary prevention.",
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AB - Periconceptional care can significantly reduce untoward pregnancy outcomes and birth defects. The avoidance of alcohol, rubella vaccination and special care for certain maternal disorders can prevent some CAs. Periconceptional multivitamin supplementation, including a physiological dose of folic acid, has been shown to reduce the occurrence of NTDs and some other major CAs. The preventable proportion of the latter group is three times higher than the incidence of NTDs. Thus, periconceptional care that includes such supplementation increases the proportion of preventable defects and improves the efficacy of primary prevention.

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