2'-, 4'-, and 6'-O-substituted 1,5,9-epideoxyloganic acids from Nepeta grandiflora

Tamás Nagy, Ákos Kocsis, Miklós Morvai, László F. Szabó, Benjamin Podányi, András Gergely, Gyula Jerkovich

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

In addition to the known 1,5,9-epideoxyloganic acid and 1,5,9- epideoxyloganin, Nepeta grandiflora has provided four new iridoid glucosides: 6'-O-acetoacetyl-, 2'-O-methyl-, 4'-O-methyl-, and 6'-O-methyl-1,5,9- epideoxyloganic acid. Their structures were proved by 1H and 13C-NMR studies. The conformation of the molecules was studied by molecular modelling and 1H NMR coupling constant analysis. The absolute configurations were supported by CD spectroscopy.

Original languageEnglish
Pages (from-to)1067-1072
Number of pages6
JournalPhytochemistry
Volume47
Issue number6
DOIs
Publication statusPublished - Mar 1998

Keywords

  • Conformational analysis
  • Iridoid glucosides
  • Lamiaceae
  • Nepeta grandiflora
  • O-substituted-1,5,9-epi-deoxyloganic acid

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Plant Science
  • Horticulture

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    Nagy, T., Kocsis, Á., Morvai, M., Szabó, L. F., Podányi, B., Gergely, A., & Jerkovich, G. (1998). 2'-, 4'-, and 6'-O-substituted 1,5,9-epideoxyloganic acids from Nepeta grandiflora. Phytochemistry, 47(6), 1067-1072. https://doi.org/10.1016/S0031-9422(98)80074-5