1,3-Dipolar cycloaddition reaction of 5-substituted pyridazinones with nitrile imines: Synthesis of pyrazolo[3,4-d]pyridazines

G. Krajsovszky, A. Gaál, N. Haider, P. Mátyus

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Reaction of 5-substituted-2-methyl-3(2H)-pyridazinones with diarylnitrile imines generated in situ has been shown to afford diarylpyrazolo[3,4-d]pyridazin-4(5H)-ones. Structures of the products were proved by nmr spectroscopy. Reactivity and regiochemistry were analyzed by FMO theory. (C) 2000 Elsevier Science B.V.

Original languageEnglish
Pages (from-to)13-18
Number of pages6
JournalJournal of Molecular Structure: THEOCHEM
Volume528
Issue number1-3
DOIs
Publication statusPublished - Aug 25 2000

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Keywords

  • 5-Substituted-2-methyl-3(2H)-pyridazinones
  • Diarylnitrile imines
  • Diarylpyrazolo[3,4-d]pyridazin-4(5H)-ones

ASJC Scopus subject areas

  • Biochemistry
  • Condensed Matter Physics
  • Physical and Theoretical Chemistry

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