Két pinealoblastomás beteg 125-jód-brachytherapiája során nyert tapasztalatok es irodalmi áttekintés.

Translated title of the contribution: 125-I brachytherapy of pineal parenchymal tumours in two patients and review of the literature

Jeno Julow, Arpád Viola, Tibor Major, István Valálik, Sarolta Sági, László Mangel, Rita Beáta Kovács, János Hável, Tibor Kiss

Research output: Contribution to journalReview article

2 Citations (Scopus)

Abstract

INTRODUCTION: Pineal parenchymal tumours make up 0.3% of all brain tumours. Stereotactic biopsy has by now become an indispensable method to detect these tumours and it can be safely performed. PATIENTS AND METHOD: Two patients with pineoblastoma were treated with 125I brachytherapy. The MRI and CT images taken 15 and 18 months after irradiation showed significant tumour shrinkage. RESULTS: Tumour volume was 0.76 cm3 in the control CT image in Case 1, a shrinkage by 73% compared to 2.87 cm3 measured at the time of planning the interstitial irradiation. In Case 2, tumour volume measured on the control MRI examination was 0.29 cm3 as opposed to 1.27 cm3 of original tumour volume, which represents a 77% shrinkage. CONCLUSION: The insertion of isotope seeds was performed at the same time as the biopsy, because thus the knowledge of the histological diagnosis could spare the patients from a second stereotactic intervention. The CT- and image fusion guided 125I stereotactic brachytherapy is a procedure that can be dosimetrically precisely planned and surgically accurately and safely performed.

Translated title of the contribution125-I brachytherapy of pineal parenchymal tumours in two patients and review of the literature
Original languageHungarian
Pages (from-to)254-262
Number of pages9
JournalIdeggyógyászati szemle
Volume58
Issue number7-8
Publication statusPublished - Jul 20 2005

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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    Julow, J., Viola, A., Major, T., Valálik, I., Sági, S., Mangel, L., Kovács, R. B., Hável, J., & Kiss, T. (2005). Két pinealoblastomás beteg 125-jód-brachytherapiája során nyert tapasztalatok es irodalmi áttekintés. Ideggyógyászati szemle, 58(7-8), 254-262.