11.1.2. Pathological findings following trigeminal neuralgia radiosurgery

G. Szeifert, I. Salmon, J. Lorenzoni, N. Massager, M. Levivier

Research output: Chapter in Book/Report/Conference proceedingChapter

11 Citations (Scopus)


Autopsy, 3D MRI and histopathological findings are presented in a patient who had suffered from trigeminal neuralgia and was treated two times by radiosurgery. The first treatment was performed with 90 Gy at the distal part of the nerve. Because of recurrent pain, a second irradiation was carried out delivering 70 Gy at a more proximal segment of the nerve 10 months later. The patient died from a hemorrhagic stroke 26 days following the second intervention. Autopsy revealed a neurovascular conflict close to the second radiosurgery shot. Histopathology demonstrated acute and chronic stage radiation-induced lesions in the trigeminal nerve.

Original languageEnglish
Title of host publicationRadiosurgery and Pathological Fundamentals
EditorsGyorgy Szeifert, Marc Levivier, Douglas Kondziolka, Dade Lunsford
Number of pages5
Publication statusPublished - Dec 1 2007

Publication series

NameProgress in Neurological Surgery
ISSN (Print)0079-6492
ISSN (Electronic)1662-3924

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

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    Szeifert, G., Salmon, I., Lorenzoni, J., Massager, N., & Levivier, M. (2007). 11.1.2. Pathological findings following trigeminal neuralgia radiosurgery. In G. Szeifert, M. Levivier, D. Kondziolka, & D. Lunsford (Eds.), Radiosurgery and Pathological Fundamentals (pp. 244-248). (Progress in Neurological Surgery; Vol. 20). https://doi.org/10.1159/000100167