• 4292 Citations
  • 37 h-Index
19962020

Research output per year

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Research Output

A CRPS-IgG-transfer-trauma model reproducing inflammatory and positive sensory signs associated with complex regional pain syndrome

Tékus, V., Hajna, Z., Borbély, É., Markovics, A., Bagoly, T., Szolcsányi, J., Thompson, V., Kemény, Á., Helyes, Z. & Goebel, A., Feb 2014, In : Pain. 155, 2, p. 299-308 10 p.

Research output: Contribution to journalArticle

50 Citations (Scopus)

Activity of botulinum toxin type A in cranial dura: Implications for treatment of migraine and other headaches

Lackovic, Z., Filipovic, B., Matak, I. & Helyes, Z., Jan 1 2016, In : British journal of pharmacology. 173, 2, p. 279-291 13 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

Age-Related Decline of Autocrine Pituitary Adenylate Cyclase-Activating Polypeptide Impairs Angiogenic Capacity of Rat Cerebromicrovascular Endothelial Cells

Banki, E., Sosnowska, D., Tucsek, Z., Gautam, T., Toth, P., Tarantini, S., Tamas, A., Helyes, Z., Reglodi, D., Sonntag, W. E., Csiszar, A. & Ungvari, Z., 2015, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 70, 6, p. 665-674 10 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Agonistic behavior of PACAP6-38 on sensory nerve terminals and cytotrophoblast cells

Reglodi, D., Borzsei, R., Bagoly, T., Boronkai, A., Racz, B., Tamas, A., Kiss, P., Horvath, G., Brubel, R., Nemeth, J., Toth, G. & Helyes, Z., Nov 1 2008, In : Journal of Molecular Neuroscience. 36, 1-3, p. 270-278 9 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Alterations in mucosal neuropeptides in patients with irritable bowel syndrome and ulcerative colitis in remission: A role in pain symptom generation?

Keszthelyi, D., Troost, F. J., Jonkers, D. M., Helyes, Z., Hamer, H. M., Ludidi, S., Vanhoutvin, S., Venema, K., Dekker, J., Szolcsányi, J. & Masclee, A. A., Oct 1 2013, In : European Journal of Pain (United Kingdom). 17, 9, p. 1299-1306 8 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

Alterations in PACAP-38-like immunoreactivity in the plasma during ictal and interictal periods of migraine patients

Tuka, B., Helyes, Z., Markovics, A., Bagoly, T., Szolcsányi, J., Szabó, N., Tóth, E., Kincses, Z. T., Vécsei, L. & Tajti, J., Oct 1 2013, In : Cephalalgia. 33, 13, p. 1085-1095 11 p.

Research output: Contribution to journalArticle

87 Citations (Scopus)

Alterations of pituitary adenylate cyclase-activatinq polypeptide-like immunoreactivity in the human plasma during pregnancy and after birth

Reglodi, D., Gyarmati, J., Ertl, T., Borzsei, R., Bodis, J., Tamas, A., Kiss, P., Csanaky, K., Banki, E., Bay, C., Nemeth, J. & Helyes, Z., Jan 1 2010, In : Journal of endocrinological investigation. 33, 7, p. 443-445 3 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)
42 Citations (Scopus)
8 Citations (Scopus)

Analgesic effects of the somatostatin sst4 receptor selective agonist J-2156 in acute and chronic pain models

Sándor, K., Elekes, K., Szabó, Á., Pintér, E., Engström, M., Wurster, S., Szolcsányi, J. & Helyes, Z., Jun 6 2006, In : European Journal of Pharmacology. 539, 1-2, p. 71-75 5 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)

Analgesic topical capsaicinoid therapy increases somatostatin-like immunoreactivity in the human plasma

Horváth, K., Boros, M., Bagoly, T., Sándor, V., Kilár, F., Kemény, Á., Helyes, Z., Szolcsányi, J. & Pintér, E., Dec 1 2014, In : Neuropeptides. 48, 6, p. 371-378 8 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Analysing the effect of I1 imidazoline receptor ligands on DSS-induced acute colitis in mice

Fehér, Á., Tóth, V. E., Al-Khrasani, M., Balogh, M., Lázár, B., Helyes, Z., Gyires, K. & Zádori, Z. S., Feb 1 2017, In : InflammoPharmacology. 25, 1, p. 107-118 12 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

A novel 3-(4,5-diphenyl-1,3-oxazol-2-yl)propanal oxime compound is a potent Transient Receptor Potential Ankyrin 1 and Vanilloid 1 (TRPA1 and V1) receptor antagonist

Payrits, M., Sághy, Mátyus, P., Czompa, A., Ludmerczki, R., Deme, R., Sándor, Z., Helyes, Z. & Szoke, Jun 2 2016, In : Neuroscience. 324, p. 151-162 12 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
138 Citations (Scopus)

Anti-inflammatory and antinociceptive effect of different somatostatin- analogs

Helyes, Z., Pinter, E., Szolcsanyi, J. & Horvath, J., Dec 1 1996, In : NEUROBIOLOGY. 4, 1-2, p. 115-117 3 p.

Research output: Contribution to journalComment/debate

11 Citations (Scopus)

Anti-inflammatory effect of synthetic somatostatin analogues in the rat

Helyes, Z., Pintér, E., Németh, J., Kéri, G., Thán, M., Oroszi, G., Horváth, A. & Szolcsányi, J., Jan 1 2001, In : British journal of pharmacology. 134, 7, p. 1571-1579 9 p.

Research output: Contribution to journalArticle

78 Citations (Scopus)
47 Citations (Scopus)

A transgenic mouse model for detection of tissue-specific thyroid hormone action

Mohácsik, P., Erdélyi, F., Baranyi, M., Botz, B., Szabó, G., Tóth, M., Haltrich, I., Helyes, Z., Sperlágh, B., Tóth, Z., Sinkó, R., Lechan, R. M., Bianco, A. C., Fekete, C. & Gereben, B., Feb 2018, In : Endocrinology. 159, 2, p. 1159-1171 13 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Body fat of rats of different age groups and nutritional states: Assessment by micro-CT and skinfold thickness

Tekus, E., Miko, A., Furedi, N., Rostas, I., Tenk, J., Kiss, T., Szitter, I., Balasko, M., Helyes, Z., Wilhelm, M. & Petervari, E., Feb 2018, In : Journal of Applied Physiology. 124, 2, p. 268-275 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Capsaicin-induced satiety is associated with gastrointestinal distress but not with the release of satiety hormones

Van Avesaat, M., Troost, F. J., Westerterp-Plantenga, M. S., Helyes, Z., Le Roux, C. W., Dekker, J., Masclee, A. A. M. & Keszthelyi, D., Feb 1 2016, In : American Journal of Clinical Nutrition. 103, 2, p. 305-313 9 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Capsaicin-sensitive sensory nerves and the trpv1 ion channel in cardiac physiology and pathologies

Szabados, T., Gömöri, K., Pálvölgyi, L., Görbe, A., Baczkó, I., Helyes, Z., Jancsó, G., Ferdinandy, P. & Bencsik, P., Jun 23 2020, In : International journal of molecular sciences. 21, 12, p. 1-23 23 p., 4472.

Research output: Contribution to journalReview article

Open Access

Capsaicin-sensitive sensory nerves exert complex regulatory functions in the serum-transfer mouse model of autoimmune arthritis

Borbély, É., Botz, B., Bölcskei, K., Kenyér, T., Kereskai, L., Kiss, T., Szolcsányi, J., Pintér, E., Csepregi, J. Z., Mócsai, A. & Helyes, Z., Mar 1 2015, In : Brain, Behavior, and Immunity. 45, p. 50-59 10 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

Capsaicin-Sensitive Sensory Nerves Mediate the Cellular and Microvascular Effects of H2S via TRPA1 Receptor Activation and Neuropeptide Release

Hajna, Z., Sághy, É., Payrits, M., Aubdool, A. A., Szőke, É., Pozsgai, G., Bátai, I. Z., Nagy, L., Filotás, D., Helyes, Z., Brain, S. D. & Pintér, E., Oct 1 2016, In : Journal of Molecular Neuroscience. 60, 2, p. 157-170 14 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Carboxamido steroids inhibit the opening properties of transient receptor potential ion channels by lipid raft modulation

Sághy, É., Payrits, M., Bíró-Sütő, T., Skoda-Földes, R., Szánti-Pintér, E., Erostyák, J., Makkai, G., Sétáló, G., Kollár, L., Kőszegi, T., Csepregi, R., Szolcsányi, J., Helyes, Z. & Szőke, É., Jan 1 2018, In : Journal of Lipid Research. 59, 10, p. 1851-1863 13 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Challenges to develop novel anti-inflammatory and analgesic drugs

Botz, B., Bölcskei, K. & Helyes, Z., May 1 2017, In : Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology. 9, 3, e1427.

Research output: Contribution to journalReview article

13 Citations (Scopus)

Changes in PACAP immunoreactivity in human milk and presence of PAC1 receptor in mammary gland during lactation

Csanaky, K., Banki, E., Szabadfi, K., Reglodi, D., Tarcai, I., Czegledi, L., Helyes, Z., Ertl, T., Gyarmati, J., Szanto, Z., Zapf, I., Sipos, E., Shioda, S. & Tamas, A., Nov 1 2012, In : Journal of Molecular Neuroscience. 48, 3, p. 631-637 7 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Changes in tracheo-bronchial sensory neuropeptide receptor gene expression pattern in rats with cisplatin-induced sensory neuropathy

Horváth, P., Szilvássy, Z., Peitl, B., Szilvássy, J., Helyes, Z., Szolcsányi, J. & Németh, J., Feb 1 2006, In : Neuropeptides. 40, 1, p. 77-83 7 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Changes of PACAP level in cerebrospinal fluid and plasma of patients with severe traumatic brain injury

Bukovics, P., Czeiter, E., Amrein, K., Kovacs, N., Pal, J., Tamas, A., Bagoly, T., Helyes, Z., Buki, A. & Reglodi, D., Oct 2014, In : Peptides. 60, p. 18-22 5 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Cigarette smoke-induced pulmonary inflammation becomes systemic by circulating extracellular vesicles containing Wnt5a and inflammatory cytokines

Feller, D., Kun, J., Ruzsics, I., Rapp, J., Sarosi, V., Kvell, K., Helyes, Z. & Pongracz, J. E., Jul 25 2018, In : Frontiers in immunology. 9, JUL, 1724.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Comparative examination of inner ear in wild type and pituitary adenylate cyclase activating polypeptide (PACAP)-Deficient mice

Tamas, A., Szabadfi, K., Nemeth, A., Fulop, B., Kiss, P., Atlasz, T., Gabriel, R., Hashimoto, H., Baba, A., Shintani, N., Helyes, Z. & Reglodi, D., May 2012, In : Neurotoxicity Research. 21, 4, p. 435-444 10 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Comparison of intestinal cold preservation injury on pituitary adenylate cyclaseactivating polypeptide in knockout and wild-type mice

Ferencz, A., Nedvig, K., Fekecs, T., Rácz, B., Wéber, G., Hashimoto, H., Baba, A., Helyes, Z. & Reglödi, D., Jul 1 2010, In : Transplantation proceedings. 42, 6, p. 2290-2292 3 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Comparison of intestinal warm ischemic injury in PACAP knockout and wild-type mice

Ferencz, A., Kiss, P., Weber, G., Helyes, Z., Shintani, N., Baba, A. & Reglodi, D., Nov 1 2010, In : Journal of Molecular Neuroscience. 42, 3, p. 435-442 8 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)
23 Citations (Scopus)

Complex regulatory role of the trpa1 receptor in acute and chronic airway inflammation mouse models

Hajna, Z., Csekő, K., Kemény, Á., Kereskai, L., Kiss, T., Perkecz, A., Szitter, I., Kocsis, B., Pintér, E. & Helyes, Z., Jun 1 2020, In : International journal of molecular sciences. 21, 11, p. 1-21 21 p., 4109.

Research output: Contribution to journalArticle

Open Access

Complex Role of Capsaicin-Sensitive Afferents in the Collagen Antibody-Induced Autoimmune Arthritis of the Mouse

Borbély, É., Kiss, T., Szabadfi, K., Pintér, E., Szolcsányi, J., Helyes, Z. & Botz, B., Dec 1 2018, In : Scientific reports. 8, 1, 15916.

Research output: Contribution to journalArticle

2 Citations (Scopus)
26 Citations (Scopus)

Contribution of platelet P2Y12 receptors to chronic Complete Freund's adjuvant-induced inflammatory pain

Bekő, K., Koványi, B., Gölöncsér, F., Horváth, G., Dénes, Környei, Z., Botz, B., Helyes, Z., Müller, C. E. & Sperlágh, B., Jun 2017, In : Journal of Thrombosis and Haemostasis. 15, 6, p. 1223-1235 13 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Contribution of the galanin system to inflammation

Kofler, B., Brunner, S., Koller, A., Wiesmayr, S., Locker, F., Lang, R., Botz, B., Kemény, À. & Helyes, Z., Dec 1 2015, In : SpringerPlus. 4, p. 1-32 32 p., L57.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Correlation of neurochemical and imaging markers in migraine: PACAP38 and DTI measures

Veréb, D., Szabó, N., Tuka, B., Tajti, J., Király, A., Faragó, P., Kocsis, K., Tóth, E., Kincses, B., Bagoly, T., Helyes, Z., Vécsei, L. & Kincses, Z. T., Sep 18 2018, In : Neurology. 91, 12, p. e1166-e1174

Research output: Contribution to journalArticle

4 Citations (Scopus)

Corrigendum to Neuropeptides in learning and memory

Borbély, É., Scheich, B. & Helyes, Z., Apr 2014, In : Neuropeptides. 48, 2, 1 p.

Research output: Contribution to journalComment/debate

Development of a new sensitive CGRP radioimmunoassay for neuropharmacological research

Nemeth, J., Gorcs, T., Helyes, Z., Oroszi, G., Kocsy, T., Pinter, E. & Szolcsanyi, J., Dec 1 1998, In : NEUROBIOLOGY. 6, 4, p. 473-475 3 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)
39 Citations (Scopus)

Differential regulatory role of pituitary adenylate cyclase-activating polypeptide in the serum-transfer arthritis model

Botz, B., Bölcskei, K., Kereskai, L., Kovács, M., Németh, T., Szigeti, K., Horváth, I., Máthé, D., Kovács, N., Hashimoto, H., Reglödi, D., Szolcsányi, J., Pintér, E., Mõcsai, A. & Helyes, Z., Oct 1 2014, In : Arthritis and Rheumatology. 66, 10, p. 2739-2750 12 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)

Divergent peripheral effects of pituitary adenylate cyclase-activating polypeptide-38 on nociception in rats and mice

Sándor, K., Bölcskei, K., McDougall, J. J., Schuelert, N., Reglodi, D., Elekes, K., Petho, G., Pintér, E., Szolcsányi, J. & Helyes, Z., Jan 1 2009, In : Pain. 141, 1-2, p. 143-150 8 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

Effect of lipid raft disruption on TRPV1 receptor activation of trigeminal sensory neurons and transfected cell line

Szoke, É., Börzsei, R., Tóth, D. M., Lengl, O., Helyes, Z., Sándor, Z. & Szolcsányi, J., Feb 25 2010, In : European Journal of Pharmacology. 628, 1-3, p. 67-74 8 p.

Research output: Contribution to journalArticle

65 Citations (Scopus)
45 Citations (Scopus)
20 Citations (Scopus)

Effects of pituitary adenylate cyclase activating polypeptide on human sperm motility

Brubel, R., Kiss, P., Vincze, A., Varga, A., Varnagy, A., Bodis, J., Mark, L., Jambor, E., Maasz, G., Hashimoto, H., Helyes, Z. S., Toth, G., Tamas, A., Koppan, M. & Reglodi, D., Nov 2012, In : Journal of Molecular Neuroscience. 48, 3, p. 623-630 8 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Effects of Some Natural Carotenoids on TRPA1- and TRPV1-Induced Neurogenic Inflammatory Processes In Vivo in the Mouse Skin

Horváth, G., Kemény, Á., Barthó, L., Molnár, P., Deli, J., Szente, L., Bozó, T., Pál, S., Sándor, K., Szőke, É., Szolcsányi, J. & Helyes, Z., May 1 2015, In : Journal of Molecular Neuroscience. 56, 1, p. 113-121 9 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Effects of synthetic analogues of human opiorphin on rat brain opioid receptors

Benyhe, Z., Toth, G., Wollemann, M., Borsodi, A., Helyes, Z., Rougeot, C. & Benyhe, S., 2014, In : Journal of Physiology and Pharmacology. 65, 4, p. 525-530 6 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)