• 998 Citations
  • 13 h-Index
1993 …2020

Research output per year

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Research Output

  • 998 Citations
  • 13 h-Index
  • 34 Article
  • 3 Review article
2020

Cellular Immune Response Involving Multinucleated Giant Hemocytes with Two-Step Genome Amplification in the Drosophilid Zaprionus indianus

Cinege, G., Lerner, Z., Magyar, L. B., Soós, B., Tóth, R., Kristó, I., Vilmos, P., Juhász, G., Kovács, A. L., Hegedus, Z., Sensen, C. W., Kurucz, É. & Andó, I., May 1 2020, In : Journal of Innate Immunity. 12, 3, p. 257-272 16 p.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)
2019

Myeloid Tribbles 1 induces early atherosclerosis via enhanced foam cell expansion

The Cardiogenics Consortium, Oct 30 2019, In : Science Advances. 5, 10, eaax9183.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

TMEM203 is a binding partner and regulator of STING-mediated inflammatory signaling in macrophages

Li, Y., James, S. J., Wyllie, D. H., Wynne, C., Czibula, A., Bukhari, A., Pye, K., Bte Mustafah, S. M., Fajka-Boja, R., Szabo, E., Angyal, A., Hegedus, Z., Kovacs, L., Hill, A. V. S., Jefferies, C. A., Wilson, H. L., Yongliang, Z. & Kiss-Toth, E., Aug 13 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 33, p. 16479-16488 10 p.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)
2018

Increased insulin-like growth factor 1 production by polyploid adipose stem cells promotes growth of breast cancer cells

Fajka-Boja, R., Marton, A., Tóth, A., Blazsó, P., Tubak, V., Bálint, B., Nagy, I., Hegedus, Z., Vizler, C. & Katona, R. L., Sep 5 2018, In : BMC cancer. 18, 1, 872.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Orthologous proteins of experimental de- and remyelination are differentially regulated in the CSF proteome of multiple sclerosis subtypes

Martin, N. A., Nawrocki, A., Molnar, V., Elkjaer, M. L., Thygesen, E. K., Palkovits, M., Acs, P., Sejbaek, T., Nielsen, H. H., Hegedus, Z., Sellebjerg, F., Molnar, T., Barbosa, E. G. V., Alcaraz, N., Gallyas, F., Svenningsen, A. F., Baumbach, J., Lassmann, H., Larsen, M. R. & Illes, Z., Aug 2018, In : PloS one. 13, 8, e0202530.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Primary cardiac angiosarcoma: A case report

Ambrus, N., Havasi, K., Kalapos, A., Sághy, L., Makai, A., Bogáts, G., Hegedűs, Z., Iványi, B., Besenyi, Z., Pápai, Z., Nagy, L., Forster, T. & Nemes, A., Feb 1 2018, In : Echocardiography. 35, 2, p. 267-271 5 p.

Research output: Contribution to journalArticle

2017

A novel ‘splice site’ HCN4 Gene mutation, c.1737 + 1 G > T, causes familial bradycardia, reduced heart rate response, impaired chronotropic competence and increased short-term heart rate variability

Hategan, L., Csányi, B., Ördög, B., Kákonyi, K., Tringer, A., Kiss, O., Orosz, A., Sághy, L., Nagy, I., Hegedűs, Z., Rudas, L., Széll, M., Varró, A., Forster, T. & Sepp, R., Aug 15 2017, In : International Journal of Cardiology. 241, p. 364-372 9 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Genes encoding cuticular proteins are components of the Nimrod gene cluster in Drosophila

Cinege, G., Zsámboki, J., Vidal-Quadras, M., Uv, A., Csordás, G., Honti, V., Gábor, E., Hegedűs, Z., Varga, G. I. B., Kovács, A. L., Juhász, G., Williams, M. J., Andó, I. & Kurucz, É., Aug 2017, In : Insect Biochemistry and Molecular Biology. 87, p. 45-54 10 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

PARP inhibition protects mitochondria and reduces ROS production via PARP-1-ATF4-MKP-1-MAPK retrograde pathway

Hocsak, E., Szabo, V., Kalman, N., Antus, C., Cseh, A., Sumegi, K., Eros, K., Hegedus, Z., Gallyas, F., Sumegi, B. & Racz, B., Jul 1 2017, In : Free Radical Biology and Medicine. 108, p. 770-784 15 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Thrombolysis agyi infarktust okozó aortadissectio esetén

Translated title of the contribution: Thrombolysis in case of ischemic stroke caused by aortic dissectionLantos, J., Nagy, A., Barna, S., Hegedűs, Z. & Bihari, K., Jan 30 2017, In : Ideggyogyaszati Szemle. 70, 1-2, p. 69-72 4 p.

Research output: Contribution to journalArticle

2016

Characterization of photomorphogenic responses and signaling cascades controlled by phytochrome-A expressed in different tissues

Kirchenbauer, D., Viczián, A., Ádám, É., Hegedűs, Z., Klose, C., Leppert, M., Hiltbrunner, A., Kircher, S., Schäfer, E. & Nagy, F., Jul 1 2016, In : The New phytologist. 211, 2, p. 584-598 15 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)
2015

Identification and functional characterisation of a novel KCNJ2 mutation, Val302del, causing andersen–tawil syndrome

Ördög, B., Hategan, L., Kovács, M., Seprényi, G., Kohajda, Z., Nagy, I., Hegedűs, Z., Környei, L., Jost, N., Katona, M., Szekeres, M., Forster, T., Papp, J. G., Varró, A. & Sepp, R., Mar 11 2015, In : Canadian journal of physiology and pharmacology. 93, 7, p. 569-575 7 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Identification of Two Novel LAMP2 Gene Mutations in Danon Disease

Csányi, B., Popoiu, A., Hategan, L., Hegedűs, Z., Nagy, V., Rácz, K., Hogye, M., Sághy, L., Iványi, B., Csanády, M., Forster, T. & Sepp, R., Nov 25 2015, (Accepted/In press) In : Canadian Journal of Cardiology.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Lack of Rybp in Mouse Embryonic Stem Cells Impairs Cardiac Differentiation

Ujhelly, O., Szabo, V., Kovacs, G., Vajda, F., Mallok, S., Prorok, J., Acsai, K., Hegedus, Z., Krebs, S., Dinnyes, A. & Pirity, M. K., Sep 15 2015, In : Stem Cells and Development. 24, 18, p. 2193-2205 13 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Loss of Tribbles pseudokinase-3 promotes Akt-driven tumorigenesis via FOXO inactivation

Salazar, M., Lorente, M., García-Taboada, E., Pérez Gómez, E., Dávila, D., Zúñiga-García, P., María Flores, J., Rodríguez, A., Hegedus, Z., Mosén-Ansorena, D., Aransay, A. M., Hernández-Tiedra, S., López-Valero, I., Quintanilla, M., Sánchez, C., Iovanna, J. L., Dusetti, N., Guzmán, M., Francis, S. E., Carracedo, A. & 2 others, Kiss-Toth, E. & Velasco, G., Jan 1 2015, In : Cell Death and Differentiation. 22, 1, p. 131-144 14 p.

Research output: Contribution to journalArticle

51 Citations (Scopus)

The absence of N-acetyl-D-glucosamine causes attenuation of virulence of Candida albicans upon interaction with vaginal epithelial cells in vitro

Manczinger, M., Bocsik, A., Kocsis, G. F., Vörös, A., Hegedus, Z., Ördögh, L., Kondorosi, É., Marton, A., Vízler, C., Tubak, V., Deli, M., Kemény, L., Nagy, I. & Lakatos, L., 2015, In : BioMed research international. 2015, 398045.

Research output: Contribution to journalArticle

2 Citations (Scopus)

TRIB3 suppresses tumorigenesis by controlling mTORC2/AKT/FOXO signaling

Salazar, M., Lorente, M., García-Taboada, E., Gómez, E. P., Dávila, D., Zúñiga-García, P., Flores, J. M., Rodríguez, A., Hegedus, Z., Mosén-Ansorena, D., Aransay, A. M., Hernández-Tiedra, S., López-Valero, I., Quintanilla, M., Sánchez, C., Iovanna, J. L., Dusetti, N., Guzmán, M., Francis, S. E., Carracedo, A. & 2 others, Kiss-Toth, E. & Velasco, G., Jul 3 2015, In : Molecular and Cellular Oncology. 2, 3, e980134.

Research output: Contribution to journalArticle

11 Citations (Scopus)
2013

Genome Wide Transcriptome Analysis of Dendritic Cells Identifies Genes with Altered Expression in Psoriasis

Filkor, K., Hegedus, Z., Szász, A., Tubak, V., Kemény, L., Kondorosi, É. & Nagy, I., Sep 9 2013, In : PloS one. 8, 9, e73435.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Selective elimination/RNAi silencing of FMRF-related peptides and their receptors decreases the locomotor activity in Drosophila melanogaster

Kiss, B., Szlanka, T., Zvara, Á., Žurovec, M., Sery, M., Kakaš, Š., Ramasz, B., HegedUs, Z., Lukacsovich, T., Puskás, L., Fónagy, A. & Kiss, I., Sep 15 2013, In : General and Comparative Endocrinology. 191, p. 137-145 9 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2011

Deep sequencing of the innate immune transcriptomic response of zebrafish embryos to Salmonella infection

Ordas, A., Hegedus, Z., Henkel, C. V., Stockhammer, O. W., Butler, D., Jansen, H. J., Racz, P., Mink, M., Spaink, H. P. & Meijer, A. H., Nov 2011, In : Fish and Shellfish Immunology. 31, 5, p. 716-724 9 p.

Research output: Contribution to journalArticle

52 Citations (Scopus)
2009

Deep sequencing of the zebrafish transcriptome response to mycobacterium infection

Hegedus, Z., Zakrzewska, A., Ágoston, V. C., Ordas, A., Rácz, P., Mink, M., Spaink, H. P. & Meijer, A. H., Sep 1 2009, In : Molecular Immunology. 46, 15, p. 2918-2930 13 p.

Research output: Contribution to journalArticle

185 Citations (Scopus)

Transcriptome profiling and functional analyses of the zebrafish embryonic innate immune response to salmonella infection

Stockhammer, O. W., Zakrzewska, A., Hegedûs, Z., Spaink, H. P. & Meijer, A. H., May 1 2009, In : Journal of Immunology. 182, 9, p. 5641-5653 13 p.

Research output: Contribution to journalArticle

153 Citations (Scopus)
2007

Tribbles: A family of kinase-like proteins with potent signalling regulatory function

Hegedus, Z., Czibula, A. & Kiss-Toth, E., Feb 1 2007, In : Cellular Signalling. 19, 2, p. 238-250 13 p.

Research output: Contribution to journalReview article

115 Citations (Scopus)
2006

Expression pattern of Filamin-240 in Drosophila blood cells

Rus, F., Kurucz, É., Márkus, R., Sinenko, S. A., Laurinyecz, B., Pataki, C., Gausz, J., Hegedus, Z., Udvardy, A., Hultmark, D. & Andó, I., Oct 2 2006, In : Gene Expression Patterns. 6, 8, p. 928-934 7 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Images in cardiology: Twiddler's syndrome in a patient with an implantable-cardioverter defibrillator

Csanadi, Z., Hegedus, Z. & Csanady, M., Jun 2006, In : Heart. 92, 6, p. 826 1 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Tribbles: Novel regulators of cell function; evolutionary aspects

Hegedus, Z., Czibula, A. & Kiss-Toth, E., Jul 2006, In : Cellular and Molecular Life Sciences. 63, 14, p. 1632-1641 10 p.

Research output: Contribution to journalReview article

68 Citations (Scopus)
2003

Hemese, a hemocyte-specific transmembrane protein, affects the cellular immune response in Drosophila

Kurucz, E., Zettervall, C. J., Sinka, R., Vilmos, P., Pivarcsi, A., Ekengren, S., Hegedüs, Z., Ando, I. & Hultmark, D., Mar 4 2003, In : Proceedings of the National Academy of Sciences of the United States of America. 100, 5, p. 2622-2627 6 p.

Research output: Contribution to journalArticle

120 Citations (Scopus)

The SBASE domain sequence library, release 10: Domain architecture prediction

Vlahoviček, K., Kaján, L., Murvai, J., Hegedus, Z. & Pongor, S., Jan 1 2003, In : Nucleic acids research. 31, 1, p. 403-405 3 p.

Research output: Contribution to journalReview article

9 Citations (Scopus)
2001

Comparative study on the effect of phosphorylated TCR zeta chain ITAM sequences on early activation events in Jurkat T cells

Chiţu, V., Fajka-Boja, R., Tóth, G. K., Váradi, G., Hegedüs, Z., Frankó, A., Szücs, K. S. & Monostori, E., Dec 2001, In : Peptides. 22, 12, p. 1963-1971 9 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
34 Citations (Scopus)
1999

Conditions for permeabilization of cells used for intracellular tyrosine phosphorylation studies

Chitu, V., Demydenko, D., Tóth, G. K., Hegedüs, Z. & Monostori, É., 1999, In : BioTechniques. 27, 3, p. 435-437 3 p.

Research output: Contribution to journalArticle

Open Access
5 Citations (Scopus)
13 Citations (Scopus)
1998
30 Citations (Scopus)
1997
3 Citations (Scopus)
1995

Application of polyacrylamide gel electrophoresis for analysis of oligopeptide phosphorylation in vitro

Hegedus, Z., Ando, I., Toth, G. K., Varadi, G. & Monostori, E., Jan 1 1995, In : BioTechniques. 18, 4, p. 631-632+634

Research output: Contribution to journalArticle

1 Citation (Scopus)
1994

Effect of phytohaemagglutinin on CD45 in T cells

Monostori, E., Hartyani, Z., Ocsovszky, I., Hegedus, Z., Oravecz, T., Kalman, M. & Ando, I., Oct 1994, In : Immunology letters. 42, 3, p. 197-201 5 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
1993

Branched polypeptides as antigens for influenza virus hemagglutinin and T-cell receptor subunits

Toth, G. K., Varadi, G., Nagy, Z., Monostori, E., Penke, B., Hegedus, Z., Ando, I., Fazekas, G., Kurucz, I., Mak, M. & Rajnavolgyi, E., Sep 1 1993, In : Peptide research. 6, 5, p. 272-280 9 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)