• 777 Citations
  • 17 h-Index
20012020

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Article
2020

Transmitted drug resistance in newly diagnosed and treatment-naïve HIV type 1-infected patients in Hungary

Áy, É., Müller, V., Mezei, M., Pocskay, Á., Koroknai, A., Müller, D., Győri, Z., Marschalkó, M., Tóth, B., Kárpáti, S., Lakatos, B., Szlávik, J., Takács, M. & Minárovits, J., Mar 2020, In : Journal of Global Antimicrobial Resistance. 20, p. 124-130 7 p.

Research output: Contribution to journalArticle

Open Access
2019

Paradoxes of tumour complexity: somatic selection, vulnerability by design, or infectious aetiology?

Apari, P. & Müller, V., Jun 2019, In : Biological Reviews. 94, 3, p. 1075-1088 14 p.

Research output: Contribution to journalArticle

Pathogen diversity drives the evolution of generalist MHC-II alleles in human populations

Manczinger, M., Boross, G., Kemény, L., Müller, V., Lenz, T. L., Papp, B. & Pál, C., 2019, In : PLoS biology. 17, 1, e3000131.

Research output: Contribution to journalArticle

Open Access
9 Citations (Scopus)
2018

An evolutionary perspective on the systems of adaptive immunity

Müller, V., de Boer, R. J., Bonhoeffer, S. & Szathmáry, E., Feb 1 2018, In : Biological Reviews. 93, 1, p. 505-528 24 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Variable effect of HIV superinfection on clinical status: Insights from mathematical modeling

Móréh, Á., Szilágyi, A., Scheuring, I. & Müller, V., Jul 23 2018, In : Frontiers in Microbiology. 9, JUL, 1634.

Research output: Contribution to journalArticle

2016

Male circumcision and the epidemic emergence of HIV-2 in West Africa

Sousa, J. D., Temudo, M. P., Hewlett, B. S., Camacho, R. J., Müller, V. & Vandamme, A. M., Dec 2016, In : PloS one. 11, 12, e0166805.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2015

HIV Competition Dynamics over Sexual Networks: First Comer Advantage Conserves Founder Effects

Ferdinandy, B., Mones, E., Vicsek, T. & Müller, V., 2015, In : PLoS computational biology. 11, 2, e1004093.

Research output: Contribution to journalArticle

4 Citations (Scopus)

The microbiome mutiny hypothesis: Can our microbiome turn against us when we are old or seriously ill?

Rózsa, L., Apari, P. & Müller, V., Jan 14 2015, In : Biology Direct. 10, 1, 3.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2014

Why Sexually Transmitted Infections Tend to Cause Infertility: An Evolutionary Hypothesis

Apari, P., de Sousa, J. D. & Müller, V., Aug 7 2014, In : PLoS Pathogens. 10, 8, e1004111.

Research output: Contribution to journalArticle

25 Citations (Scopus)
2013

A genome-to-genome analysis of associations between human genetic variation, HIV-1 sequence diversity, and viral control

Bartha, I., Carlson, J. M., Brumme, C. J., McLaren, P. J., Brumme, Z. L., John, M., Haas, D. W., Martinez-Picado, J., Dalmau, J., López-Galíndez, C., Casado, C., Rauch, A., Günthard, H. F., Bernasconi, E., Vernazza, P., Klimkait, T., Yerly, S., O'Brien, S. J., Listgarten, J., Pfeifer, N. & 9 others, Lippert, C., Fusi, N., Kutalik, Z., Allen, T. M., Müller, V., Richard Harrigan, P., Heckerman, D., Telenti, A. & Fellay, J., Oct 29 2013, In : eLife. 2013, 2, e01123.

Research output: Contribution to journalArticle

65 Citations (Scopus)

Gag-Pol Processing during HIV-1 Virion Maturation: A Systems Biology Approach

Könnyu, B., Sadiq, S. K., Turányi, T., Hírmondó, R., Müller, B., Kräusslich, H. G., Coveney, P. V. & Müller, V., Jun 1 2013, In : PLoS computational biology. 9, 6, e1003103.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Superinfection with drug-resistant HIV is rare and does not contribute substantially to therapy failure in a large European cohort

Bartha, I., Assel, M., Sloot, P. M. A., Zazzi, M., Torti, C., Schülter, E., Luca, A. D., Sönnerborg, A., Abecasis, A. B., Van Laethem, K., Rosi, A., Svärd, J., Paredes, R., van de Vijver, D. A. M. C., Vandamme, A. M. & Müller, V., Nov 12 2013, In : BMC Infectious Diseases. 13, 1, 537.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2012

Enhanced heterosexual transmission hypothesis for the origin of pandemic HIV-1

de Sousa, J. D., Alvarez, C., Vandamme, A. M. & Müller, V., Oct 2012, In : Viruses. 4, 10, p. 1950-1983 34 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Is the virulence of HIV changing? A meta-analysis of trends in prognostic markers of HIV disease progression and transmission

Herbeck, J. T., Müller, V., Maust, B. S., Ledergerber, B., Tortie, C., Di Giambenedetto, S., Gras, L., Günthard, H. F., Jacobsonh, L. P., Mullins, J. I. & Gottlieb, G. S., Jan 14 2012, In : AIDS. 26, 2, p. 193-205 13 p.

Research output: Contribution to journalArticle

55 Citations (Scopus)

Mutations in HIV-1 gag and pol compensate for the loss of viral fitness caused by a highly mutated protease

Kožíšek, M., Henke, S., Šašková, K. G., Jacobs, G. B., Schuch, A., Buchholz, B., Müller, V., Kräusslich, H. G., Řezáčová, P., Konvalinka, J. & Bodem, J., Aug 2012, In : Antimicrobial agents and chemotherapy. 56, 8, p. 4320-4330 11 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)
2011

A strong case for viral genetic factors in HIV virulence

Müller, V., Fraser, C. & Herbeck, J. T., Mar 2011, In : Viruses. 3, 3, p. 204-216 13 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Reaction kinetics of catalyzed competitive heteropolymer cleavage

Sadiq, S. K., Könnyü, B., Müller, V. & Coveney, P. V., Sep 22 2011, In : Journal of Physical Chemistry B. 115, 37, p. 11017-11027 11 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2010

Comparison of HIV-1 genotypic resistance test interpretation systems in predicting virological outcomes over time

Frentz, D., Boucher, C. A. B., Assel, M., de Luca, A., Fabbiani, M., Incardona, F., Libin, P., Manca, N., Müller, V., Nualláin, B. Ó., Paredes, R., Prosperi, M., Quiros-Roldan, E., Ruiz, L., Sloot, P. M. A., Torti, C., Vandamme, A. M., van Laethem, K., Zazzi, M. & van de Vijver, D. A. M. C., Aug 13 2010, In : PloS one. 5, 7, e11505.

Research output: Contribution to journalArticle

46 Citations (Scopus)

High GUD incidence in the early 20th century created a particularly permissive time window for the origin and initial spread of epidemic HIV strains

de Sousa, J. D., Müller, V., Lemey, P. & Vandamme, A. M., 2010, In : PloS one. 5, 4, e9936.

Research output: Contribution to journalArticle

34 Citations (Scopus)
2009

African descent is associated with slower CD4 cell count decline in treatment-naive patients of the Swiss HIV Cohort Study

Müller, V., Von Wyl, V., Yerly, S., Böni, J., Klimkait, T., Bürgisser, P., Ledergerber, B., Günthard, H. F. & Bonhoeffer, S., Jun 19 2009, In : AIDS. 23, 10, p. 1269-1276 8 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

HIV decision support: From molecule to man

Sloot, P. M. A., Coveney, P. V., Ertaylan, G., Müller, V., Boucher, C. A. & Bubak, M., Jul 13 2009, In : Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences. 367, 1898, p. 2691-2703 13 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

Increasing clinical virulence in two decades of the Italian HIV epidemic

Müller, V., Maggiolo, F., Suter, F., Ladisa, N., De Luca, A., Antinori, A., Sighinolfi, L., Quiros-Roldan, E., Carosi, G. & Torti, C., May 2009, In : PLoS Pathogens. 5, 5, e1000454.

Research output: Contribution to journalArticle

27 Citations (Scopus)
2008

Has HIV evolved to induce immune pathogenesis?

Bartha, I., Simon, P. & Müller, V., Jul 1 2008, In : Trends in Immunology. 29, 7, p. 322-328 7 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)
2007

Evolution of a novel 5-amino-acid insertion in the β3-β4 loop of HIV-1 reverse transcriptase

Huigen, M. C. D. G., de Graaf, L., Eggink, D., Schuurman, R., Müller, V., Stamp, A., Stammers, D. K., Boucher, C. A. B. & Nijhuis, M., Aug 1 2007, In : Virology. 364, 2, p. 395-406 12 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
2006

Stable virulence levels in the HIV epidemic of Switzerland over two decades

Müller, V., Ledergerber, B., Perrin, L., Klimkait, T., Furrer, H., Telenti, A., Bernasconi, E., Vernazza, P., Günthard, H. F. & Bonhoeffer, S., Apr 1 2006, In : AIDS. 20, 6, p. 889-894 6 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)
2003

Glancing behind virus load variation in HIV-1 infection

Bonhoeffer, S., Funk, G. A., Günthard, H. F., Fischer, M. & Müller, V., Nov 2003, In : Trends in Microbiology. 11, 11, p. 499-504 6 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)

Quantitative constraints on the scope of negative selection

Müller, V. & Bonhoeffer, S., Mar 1 2003, In : Trends in Immunology. 24, 3, p. 132-135 4 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)
2002

Decelerating decay of latently infected cells during prolonged therapy for human immunodeficiency virus type 1 infection

Müller, V., Vigueras-Gómez, J. F. & Bonhoeffer, S., Aug 20 2002, In : Journal of Virology. 76, 17, p. 8963-8965 3 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)
2001

Release of virus from lymphoid tissue affects human immunodeficiency virus type 1 and hepatitis C virus kinetics in the blood

Müller, V., Marée, A. F. M. & De Boer, R. J., 2001, In : Journal of Virology. 75, 6, p. 2597-2603 7 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)