• 1070 Citations
  • 19 h-Index
19962019

Research output per year

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Research Output

  • 1070 Citations
  • 19 h-Index
  • 51 Article
  • 2 Review article
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Article
6 Citations (Scopus)

1-phenyl-2-(propylamino)pentane, a memory enhancer

Simon, K., Harmat, V., Torok, Z., Bocskei, Z. & Hermecz, I., Jan 1 1996, In : Acta Crystallographica, Section C: Crystal Structure Communications. 52, pt 8, p. 2090-2092 3 p.

Research output: Contribution to journalArticle

A new potent calmodulin antagonist with arylalkylamine structure: Crystallographic, spectroscopic and functional studies

Harmat, V., Böcskei, Z., Náray-Szabó, G., Bata, I., Csutor, A. S., Hermecz, I., Arányi, P., Szabó, B., Liliom, K., Vértessy, B. G. & Ovádi, J., Mar 31 2000, In : Journal of molecular biology. 297, 3, p. 747-755 9 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

Approaches to Pyranuronic β-Sugar Amino Acid Building Blocks of Peptidosaccharide Foldamers

Goldschmidt Gőz, V., Pintér, I., Harmat, V. & Perczel, A., Jan 23 2018, In : European Journal of Organic Chemistry. 2018, 3, p. 355-361 7 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Aromatic stacking between nucleobase and enzyme promotes phosphate ester hydrolysis in dUTPase

Pecsi, I., Leveles, I., Harmat, V., Vertessy, B. G. & Toth, J., Nov 1 2010, In : Nucleic acids research. 38, 20, p. 7179-7186 8 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)

A self-compartmentalizing hexamer serine protease from Pyrococcus Horikoshii: Substrate selection achieved through multimerization

Menyhárd, D. K., Kiss-Szemán, A., Tichy-Rács, É., Hornung, B., Rádi, K., Szeltner, Z., Domokos, K., Szamosi, I., Náray-Szabó, G., Polgár, L. & Harmat, V., Jun 14 2013, In : Journal of Biological Chemistry. 288, 24, p. 17884-17894 11 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

A true autoactivating enzyme: Structural insight into mannose-binding lectin-associated serine protease-2 activations

Gál, P., Harmat, V., Kocsis, A., Bián, T., Barna, L., Ambrus, G., Végh, B., Balczer, J., Sim, R. B., Náray-Szabó, G. & Závodszky, P., Sep 30 2005, In : Journal of Biological Chemistry. 280, 39, p. 33435-33444 10 p.

Research output: Contribution to journalArticle

83 Citations (Scopus)

Az 1-[(trifluor-metil)fenil]pirrolok regioszelektív metallálási reakciói

Translated title of the contribution: Regioselective metalation reactions of 1-[(trifluoromethyl)phenyl]pyrrolesFaigl, F., Fogassy, K., Szucs, E., Kovács, K., Töke, L., Keserü, G. M., Harmat, V. & Böcskei, Z., Jul 2002, In : Magyar Kemiai Folyoirat, Kemiai Kozlemenyek. 108, 7, p. 317-324 8 p.

Research output: Contribution to journalArticle

C1 inhibitor serpin domain structure reveals the likely mechanism of heparin potentiation and conformational disease

Beinrohr, L., Harmat, V., Dobó, J., Lörincz, Z., Gál, P. & Závodszky, P., Jul 20 2007, In : Journal of Biological Chemistry. 282, 29, p. 21100-21109 10 p.

Research output: Contribution to journalArticle

72 Citations (Scopus)
5 Citations (Scopus)
9 Citations (Scopus)

Crystal and solution structures of calcium complexes relevant to problematic waste disposal: calcium gluconate and calcium isosaccharinate

Bugris, V., Dudás, C., Kutus, B., Harmat, V., Csankó, K., Brockhauser, S., Pálinkó, I., Turner, P. & Sipos, P., Dec 1 2018, In : Acta Crystallographica Section B: Structural Science, Crystal Engineering and Materials. 74, 6, p. 598-609 12 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
4 Citations (Scopus)

Direct contacts between conserved motifs of different subunits provide major contribution to active site organization in human and mycobacterial dUTPases

Takács, E., Nagy, G., Leveles, I., Harmat, V., Lopata, A., Tóth, J. & Vértessy, B. G., Jul 2010, In : FEBS letters. 584, 14, p. 3047-3054 8 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Directed evolution reveals the binding motif preference of the LC8/DYNLL hub protein and predicts large numbers of novel binders in the human proteome

Rapali, P., Radnai, L., Süveges, D., Harmat, V., Tölgyesi, F., Wahlgren, W. Y., Katona, G., Nyitray, L. & Pál, G., Apr 29 2011, In : PloS one. 6, 4, e18818.

Research output: Contribution to journalArticle

40 Citations (Scopus)

Effect of a trifluoromethyl group on molecular structure: Competitive mono- and dilithiation of 1-[(trifluoromethyl)phenyl]pyrroles

Faigl, F., Fogassy, K., Szucs, E., Kovács, K., Keseru, G. M., Harmat, V., Böcskei, Z. & Toke, L., Jun 18 1999, In : Tetrahedron. 55, 25, p. 7881-7892 12 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Efficient synthesis and resolution of (±)-1-[2-carboxy-6-(trifluoromethyl)phenyl]pyrrole-2-carboxylic acid

Fogassy, K., Harmat, V., Böcskei, Z., Tárkányi, G., Toke, L. & Faigl, F., Dec 1 2000, In : Tetrahedron Asymmetry. 11, 23, p. 4771-4780 10 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Enzyme:substrate hydrogen bond shortening during the acylation phase of serine protease catalysis

Fodor, K., Harmat, V., Neutze, R., Szilágyi, L., Gráf, L. & Katona, G., Feb 21 2006, In : Biochemistry. 45, 7, p. 2114-2121 8 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)
41 Citations (Scopus)

Flexible segments modulate co-folding of dUTPase and nucleocapsid proteins

Németh-Pongrácz, V., Barabás, O., Fuxreiter, M., Simon, I., Pichová, I., Rumlová, M., Zábranská, H., Svergun, D., Petoukhov, M., Harmat, V., Klement, É., Hunyadi-Gulyás, É., Medzihradszky, K. F., Kónya, E. & Vértessy, B. G., Jan 1 2007, In : Nucleic acids research. 35, 2, p. 495-505 11 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)

Fragmentation-related phosphinylations using 2-aryl-2-phosphabicyclo[2.2.2]oct-5-ene- and -octa-5,7-diene 2-oxides

Keglevich, G., Szelke, H., Bálint, Á., Imre, T., Ludányi, K., Nagy, Z., Hanusz, M., Simon, K., Harmat, V. & Toke, L., Aug 18 2003, In : Heteroatom Chemistry. 14, 5, p. 443-451 9 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Geometry and electronic structure of silylated hydroxylamine and carbamic acid derivatives

Csonka, I. P., Mörtl, M., Knausz, D., Harmat, V. & Szepes, L., May 5 1999, In : Journal of Organometallic Chemistry. 579, 1-2, p. 38-44 7 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Isostructural metabolites of two anti-Parkinson drugs

Simon, K., Harmat, V., Török, Z., Böcskei, Z. & Hermecz, I., Jan 1 1998, In : Acta Crystallographica Section C: Crystal Structure Communications. 54, 6, p. 811-813 3 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Lipophilicity of aminopyridazinone regioisomers

Anwair, M. A. S., Károlyházy, L., Szabó, D., Balogh, B., Kövesdi, I., Harmat, V., Krenyácz, J., Gellért, Á., Takács-Novák, K. & Mátyus, P., Aug 27 2003, In : Journal of Agricultural and Food Chemistry. 51, 18, p. 5262-5270 9 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

MASP-1, a promiscuous complement protease: Structure of its catalytic region reveals the basis of its broad specificity

Dobó, J., Harmat, V., Beinrohr, L., Sebestyén, E., Závodszky, P. & Gál, P., Jul 15 2009, In : Journal of Immunology. 183, 2, p. 1207-1214 8 p.

Research output: Contribution to journalArticle

83 Citations (Scopus)

Novel ortho- and peri-fused pyridazine ring systems

Éliás, O., Károlyházy, L., Horváth, G., Harmat, V. & Mátyus, P., Dec 29 2003, In : Journal of Molecular Structure: THEOCHEM. 666-667, p. 625-636 12 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Novel ring transformations of condensed [1,2,4]triazolo[4,3-b]pyridazine-6(5H)-one-3(2H)-thiones effected by dialkyl-acetylenedicarboxylates

Simó, M., Csámpai, A., Harmat, V., Barabás, O. & Magyarfalvy, G., Aug 13 2001, In : Tetrahedron. 57, 33, p. 7191-7198 8 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

One-pot transformation of cyclic phosphine oxides to phosphine-boranes by dimethyl sulfide-borane

Keglevich, G., Fekete, M., Chuluunbaatar, T., Dobó, A., Harmat, V. & Toke, L., Dec 1 2000, In : Journal of the Chemical Society, Perkin Transactions 1. 24, p. 4451-4455 5 p.

Research output: Contribution to journalArticle

50 Citations (Scopus)

Origin of problems related to Staudinger reduction in carbopeptoid syntheses

Csordás, B., Nagy, A., Harmat, V., Zsoldos-Mády, V., Leveles, I., Pintér, I., Farkas, V. & Perczel, A., Jul 20 2016, (Accepted/In press) In : Amino Acids. p. 1-15 15 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Prolyl oligopeptidase inhibition by N-acyl-pro-pyrrolidine-type molecules

Kánai, K., Arányi, P., Böcskei, Z., Ferenczy, G., Harmat, V., Simon, K., Bátori, S., Náray-Szabó, G. & Hermecz, I., Dec 11 2008, In : Journal of Medicinal Chemistry. 51, 23, p. 7514-7522 9 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)
17 Citations (Scopus)

Quantitative characterization of the activation steps of mannan-binding lectin (MBL)-associated serine proteases (MASPs) points to the central role of MASP-1 in the initiation of the complement lectin pathway

Megyeri, M., Harmat, V., Major, B., Végh, Á., Balczer, J., Héja, D., Szilágyi, K., Datz, D., Pál, G., Závodszky, P., Gál, P. & Dobó, J., Mar 29 2013, In : Journal of Biological Chemistry. 288, 13, p. 8922-8934 13 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)

Radiation-damage investigation of a DNA 16-mer

Bugris, V., Harmat, V., Ferenc, G., Brockhauser, S., Carmichael, I. & Garman, E. F., Jul 1 2019, In : Journal of Synchrotron Radiation. 26, p. 998-1009 12 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Reaction of cyclopropane carboxylic acid derivatives with sulphur tetrafluoride - An example of a diastereoselective ring opening

Hell, Z., Finta, Z., Dmowski, W., Faigl, F., Pustovit, Y. M., Toke, L. & Harmat, V., Jul 2000, In : Journal of Fluorine Chemistry. 104, 2, p. 297-301 5 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Revisiting the mechanism of the autoactivation of the complement protease C1r in the C1 complex: Structure of the active catalytic region of C1r

Kardos, J., Harmat, V., Palló, A., Barabás, O., Szilágyi, K., Gráf, L., Náray-Szabó, G., Goto, Y., Závodszky, P. & Gál, P., Mar 1 2008, In : Molecular Immunology. 45, 6, p. 1752-1760 9 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)
59 Citations (Scopus)

Steric hindrance in the synthesis and properties of the dimer of 1-(2,4,6-tri-tert-butylphenyl)phosphole 1-oxide

Keglevich, G., Toke, L., Böcskei, Z. & Harmat, V., Jan 1 1997, In : Heteroatom Chemistry. 8, 6, p. 527-531 5 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Structural and kinetic contributions of the oxyanion binding site to the catalytic activity of acylaminoacyl peptidase

Kiss, A. L., Palló, A., Náray-Szabó, G., Harmat, V. & Polgár, L., May 1 2008, In : Journal of Structural Biology. 162, 2, p. 312-323 12 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Structural evidence for non-canonical binding of Ca 2+ to a canonical EF-hand of a conventional myosin

Debreczeni, J. É., Farkas, L., Harmat, V., Hetényi, C., Hajdú, I., Závodszky, P., Kohama, K. & Nyitray, L., Dec 16 2005, In : Journal of Biological Chemistry. 280, 50, p. 41458-41464 7 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Structure and catalysis of acylaminoacyl peptidase: Closed and open subunits of a dimer oligopeptidase

Harmat, V., Domokos, K., Menyhárd, D. K., Palló, A., Szeltner, Z., Szamosi, I., Beke-Somfai, T., Náray-Szabó, G. & Polgár, L., Jan 21 2011, In : Journal of Biological Chemistry. 286, 3, p. 1987-1998 12 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)

Structure and enzymatic mechanism of a moonlighting dUTPase

Leveles, I., Németh, V., Szabó, J. E., Harmat, V., Nyíri, K., Bendes, Á. Á., Papp-Kádár, V., Zagyva, I., Róna, G., Ozohanics, O., Vékey, K., Tóth, J. & Vértessy, B. G., Dec 1 2013, In : Acta Crystallographica Section D: Biological Crystallography. 69, 12, p. 2298-2308 11 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)
5 Citations (Scopus)
1 Citation (Scopus)

Surprisingly great difference in reactivity depending upon the ring size: Solvolysis and molecular structure study of some N-trimethylsilylated cyclic ureas

Szalay, R., Pongor, G., Harmat, V., Böcskei, Z. & Knausz, D., Mar 15 2005, In : Journal of Organometallic Chemistry. 690, 6, p. 1498-1506 9 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)
4 Citations (Scopus)

Synthesis and fragmentation of new 2-phosphabicyclo[2.2.2]octene 2-oxides

Keglevich, G., Szelke, H., Tamás, A., Harmat, V., Ludányi, K., Vaskó, Á. G. & Toke, L., Jan 1 2002, In : Heteroatom Chemistry. 13, 7, p. 626-632 7 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

The Acylaminoacyl Peptidase from Aeropyrum pernix K1 Thought to Be an Exopeptidase Displays Endopeptidase Activity

Kiss, A. L., Hornung, B., Rádi, K., Gengeliczki, Z., Sztáray, B., Juhász, T., Szeltner, Z., Harmat, V. & Polgár, L., Apr 27 2007, In : Journal of molecular biology. 368, 2, p. 509-520 12 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

The molecular transform as a tool for quantification of molecular similarity

Náray-Szabó, G. & Harmat, V., Dec 1 1997, In : Match. 35, p. 29-40 12 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
65 Citations (Scopus)