• 7005 Citations
  • 26 h-Index
19982019

Research output per year

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Research Output

Article

A new aspect to the origin and evolution of eukaryotes

Vellai, T., Takács, K. & Vida, G., May 11 1998, In : Journal of Molecular Evolution. 46, 5, p. 499-507 9 p.

Research output: Contribution to journalArticle

92 Citations (Scopus)

A novel actin binding site of myosin required for effective muscle contraction

Várkuti, B. H., Yang, Z., Kintses, B., Erdélyi, P., Bárdos-Nagy, I., Kovács, A. L., Hári, P., Kellermayer, M., Vellai, T. & Málnási-Csizmadia, A., Mar 1 2012, In : Nature Structural and Molecular Biology. 19, 3, p. 299-306 8 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)

A second report from the EMBO conference on autophagy: Mechanism, regulation and selectivity of autophagy

Vellai, T. & Klionsky, D. J., Jan 1 2010, In : Autophagy. 6, 1, p. 197-198 2 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

AUTEN-67, an autophagy-enhancing drug candidate with potent antiaging and neuroprotective effects

Papp, D., Kovács, T., Billes, V., Varga, M., Tarnóci, A., Hackler, L., Puskás, L., Liliom, H., Tárnok, K., Schlett, K., Borsy, A., Pádár, Z., Kovács, A., Hegedűs, K., Juhász, G., Komlós, M., Erdős, A., Gulyás, B. & Vellai, T., Jan 1 2016, In : Autophagy. 12, 2, p. 273-286 14 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

AUTEN-67 (Autophagy Enhancer-67) Hampers the Progression of Neurodegenerative Symptoms in a Drosophila model of Huntington's Disease

Billesa, V., Kovacs, T., Hotzi, B., Manzeger, A., Tagscherer, K., Komlos, M., Tarnocia, A., Padar, Z., Erdos, A., Bjelik, A., Legradi, A., Gulya, K., Gulyas, B. & Vellai, T., Jan 1 2016, In : Journal of Huntington's Disease. 5, 2, p. 133-147 15 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Autophagy genes unc-51 and bec-1 are required for normal cell size in Caenorhabditis elegans

Aladzsity, I., Tóth, M. L., Sigmond, T., Szabó, E., Bicsák, B., Barna, J., Regos, Á., Orosz, L., Kovács, A. L. & Vellai, T., Sep 1 2007, In : Genetics. 177, 1, p. 655-660 6 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Autophagy in zebrafish

Varga, M., Fodor, E. & Vellai, T., Mar 15 2015, In : Methods. 75, p. 172-180 9 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Autophagy is required for zebrafish caudal fin regeneration

Varga, M., Sass, M., Papp, D., Takács-Vellai, K., Kobolak, J., Dinnyés, A., Klionsky, D. J. & Vellai, T., Apr 1 2014, In : Cell Death and Differentiation. 21, 4, p. 547-556 10 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)

Autophagy regulatory network - A systemslevel bioinformatics resource for studying the mechanism and regulation of autophagy

Türei, D., Földvári-Nagy, L., Fazekas, D., Módos, D., Kubisch, J., Kadlecsik, T., Demeter, A., Lenti, K., Csermely, P., Vellai, T. & Korcsmáros, T., Jan 1 2015, In : Autophagy. 11, 1, p. 155-165 11 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)

Base excision repair AP endonucleases and mismatch repair act together to induce checkpoint-mediated autophagy

Sengupta, T., Torgersen, M. L., Kassahun, H., Vellai, T., Simonsen, A. & Nilsen, H., Jan 1 2013, In : Nature communications. 4, 2578.

Research output: Contribution to journalArticle

34 Citations (Scopus)

Developmentally regulated autophagy is required for eye formation in Drosophila

Billes, V., Kovács, T., Manzéger, A., Lőrincz, P., Szincsák, S., Regős, Á., Kulcsár, P. I., Korcsmáros, T., Lukácsovich, T., Hoffmann, G., Erdélyi, M., Mihály, J., Takács-Vellai, K., Sass, M. & Vellai, T., Sep 2 2018, In : Autophagy. 14, 9, p. 1499-1519 21 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Distribution and evolution of short tandem repeats in closely related bacterial genomes

Kassai-Jáger, E., Ortutay, C., Tóth, G., Vellai, T. & Gáspári, Z., Feb 29 2008, In : Gene. 410, 1, p. 18-25 8 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Effects of sex and insulin/insulin-like growth factor-1 signaling on performance in an associative learning paradigm in Caenorhabditis elegans

Vellai, T., McCulloch, D., Gems, D. & Kovács, A. L., Sep 27 2006, In : Genetics. 174, 1, p. 309-316 8 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

Functional fine-tuning between bacterial DNA recombination initiation and quality control systems

Ferencziová, V., Harami, G. M., Németh, J. B., Vellai, T. & Kovács, M., Feb 1 2018, In : PLoS One. 13, 2, e0192483.

Research output: Contribution to journalArticle

Gel electrophoretic restriction fragment length polymorphism analysis of DNA derived from individual nematodes, using the PhastSystem

Triga, D., Pamjav, H., Vellai, T., Fodor, A. & Buzás, Z., Jun 16 1999, In : ELECTROPHORESIS. 20, 6, p. 1274-1279 6 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Genome economization and a new approach to the species concept in bacteria

Vellai, T., Kovács, A. L., Kovács, G., Ortutay, C. & Vida, G., Oct 7 1999, In : Proceedings of the Royal Society B: Biological Sciences. 266, 1432, p. 1953-1958 6 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Heat shock factor-1 intertwines insulin/IGF-1, TGF-β and cGMP signaling to control development and aging

Barna, J., Princz, A., Kosztelnik, M., Hargitai, B., Takács-Vellai, K. & Vellai, T., Jan 1 2012, In : BMC developmental biology. 12, 1, 32.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Highly efficient RNAi and Cas9-based auto-cloning systems for C. Elegans research

Sturm, Á., Saskoï, É., Tibor, K., Weinhardt, N. & Vellai, T., Jan 1 2018, In : Nucleic acids research. 46, 17, e105.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Identification of novel cis-regulatory regions from the Notch receptor genes lin-12 and glp-1 of Caenorhabditis elegans

Regos, Á., Lengyel, K., Takács-Vellai, K. & Vellai, T., Feb 18 2013, In : Gene Expression Patterns. 13, 3-4, p. 66-77 12 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Identifying novel genes involved in both deer physiological and human pathological osteoporosis

Borsy, A., Podani, J., Stéger, V., Balla, B., Horváth, A., Kósa, J. P., Gyurján, I., Molnár, A., Szabolcsi, Z., Szabó, L., Jakó, E., Zomborszky, Z., Nagy, J., Semsey, S., Vellai, T., Lakatos, P. & Orosz, L., Mar 1 2009, In : Molecular Genetics and Genomics. 281, 3, p. 301-313 13 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Inactivation of the autophagy Gene bec-1 triggers apoptotic cell death in C. elegans

Takacs-Vellai, K., Vellai, T., Puoti, A., Passannante, M., Wicky, C., Streit, A., Kovacs, A. L. & Müller, F., Aug 23 2005, In : Current Biology. 15, 16, p. 1513-1517 5 p.

Research output: Contribution to journalArticle

172 Citations (Scopus)

Influence of autophagy genes on ion-channel-dependent neuronal degeneration in Caenorhabditis elegans

Tóth, M. L., Simon, P., Kovács, A. L. & Vellai, T., Mar 15 2007, In : Journal of cell science. 120, 6, p. 1134-1141 8 p.

Research output: Contribution to journalArticle

53 Citations (Scopus)

Influence of TOR kinase on lifespan in C. elegans

Vellai, T., Takacs-Vellai, K., Zhang, Y., Kovacs, A. L., Orosz, L. & Müller, F., Dec 11 2003, In : Nature. 426, 6967, 1 p.

Research output: Contribution to journalArticle

700 Citations (Scopus)

Longevity pathways converge on autophagy genes to regulate life span in Caenorhabditis elegans

Tóth, M. L., Sigmond, T., Borsos, É., Barna, J., Erdélyi, P., Takács-Vellai, K., Orosz, L., Kovács, A. L., Csikós, G., Sass, M. & Vellai, T., Apr 1 2008, In : Autophagy. 4, 3, p. 330-338 9 p.

Research output: Contribution to journalArticle

Open Access
255 Citations (Scopus)

Mannich Curcuminoids as Potent Anticancer Agents

Gyuris, M., Hackler, L., Nagy, L. I., Alföldi, R., Rédei, E., Marton, A., Vellai, T., Faragó, N., Ózsvári, B., Hetényi, A., Tóth, G., Sipos, P., Kanizsai, I. & Puskás, L., Jul 1 2017, In : Archiv der Pharmazie. 350, 7, e1700005.

Research output: Contribution to journalArticle

13 Citations (Scopus)

NDK-1, the homolog of NM23-H1/H2 regulates cell migration and apoptotic engulfment in C. elegans

Fancsalszky, L., Monostori, E., Farkas, Z., Pourkarimi, E., Masoudi, N., Hargitai, B., Bosnar, M. H., Deželjin, M., Zsákai, A., Vellai, T., Mehta, A. & Takács-Vellai, K., Mar 21 2014, In : PloS one. 9, 3, e92687.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Neighbours of cancer-related proteins have key influence on pathogenesis and could increase the drug target space for anticancer therapies

Módos, D., Bulusu, K. C., Fazekas, D., Kubisch, J., Brooks, J., Marczell, I., Szabó, P. M., Vellai, T., Csermely, P., Lenti, K., Bender, A. & Korcsmáros, T., Dec 1 2017, In : npj Systems Biology and Applications. 3, 1, 2.

Research output: Contribution to journalArticle

7 Citations (Scopus)

No correlation between endo-and exoskeletal regenerative capacities in teleost species

Pápai, N., Kagan, F., Csikós, G., Kosztelnik, M., Vellai, T. & Varga, M., Jan 1 2019, In : Fishes. 4, 4, 51.

Research output: Contribution to journalArticle

Open Access

Novel application of PhastSystem polyacrylamide gel electrophoresis using restriction fragment length polymorphism - Internal transcribed spacer patterns of individuals for molecular identification of entomopathogenic nematodes

Pamjav, H., Triga, D., Buzás, Z., Vellai, T., Lucskai, A., Adams, B., Reid, A. P., Burnell, A., Griffin, C., Glazer, I., Klein, M. G. & Fodor, A., Jan 1 1999, In : ELECTROPHORESIS. 20, 6, p. 1266-1273 8 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Prediction and characterization of human ageing-related proteins by using machine learning

Kerepesi, C., Daróczy, B., Sturm, Á., Vellai, T. & Benczúr, A., Dec 1 2018, In : Scientific Reports. 8, 1, 4094.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Qualitative and quantitative characterization of autophagy in Caenorhabditis elegans by electron microscopy.

Sigmond, T., Fehér, J., Baksa, A., Pásti, G., Pálfia, Z., Takács-Vellai, K., Kovács, J., Vellai, T. & Kovács, A. L., 2008, In : Methods in enzymology. 451, p. 467-491 25 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Regulation of cell growth by autophagy

Vellai, T., Bicsák, B., Tóth, M. L., Takács-Vellai, K. & Kovács, A. L., May 16 2008, In : Autophagy. 4, 4, p. 507-509 3 p.

Research output: Contribution to journalArticle

Open Access
28 Citations (Scopus)

Roles of heat shock factor 1 beyond the heat shock response

Barna, J., Csermely, P. & Vellai, T., May 17 2018, (Accepted/In press) In : Cellular and Molecular Life Sciences. p. 1-20 20 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Sex-specific regulation of aging in Caenorhabditis elegans

Hotzi, B., Kosztelnik, M., Hargitai, B., Takács-Vellai, K., Barna, J., Bördén, K., Málnási-Csizmadia, A., Lippai, M., Ortutay, C., Bacquet, C., Pasparaki, A., Arányi, T., Tavernarakis, N. & Vellai, T., Jun 2018, In : Aging cell. 17, 3, e12724.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Shared developmental roles and transcriptional control of autophagy and apoptosis in Caenorhabditis elegans

Erdélyi, P., Borsos, É., Takács-Vellai, K., Kovács, T., Kovács, A. L., Sigmond, T., Hargitai, B., Pásztor, L., SenGupta, T., Dengg, M., Pécsi, I., Tóth, J., Nilsen, H., Vértessy, B. G. & Vellai, T., May 1 2011, In : Journal of cell science. 124, 9, p. 1510-1518 9 p.

Research output: Contribution to journalArticle

Open Access
27 Citations (Scopus)

SignaFish: A Zebrafish-specific signaling pathway resource

Csályi, K., Fazekas, D., Kadlecsik, T., Türei, D., Gul, L., Horváth, B., Módos, D., Demeter, A., Pápai, N., Lenti, K., Csermely, P., Vellai, T., Korcsmáros, T. & Varga, M., Jan 1 2016, In : Zebrafish. 13, 6, p. 541-544 4 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

SignaLink 2 - a signaling pathway resource with multi-layered regulatory networks.

Fazekas, D., Koltai, M., Türei, D., Módos, D., Pálfy, M., Dúl, Z., Zsákai, L., Szalay-Beko, M., Lenti, K., Farkas, I. J., Vellai, T., Csermely, P. & Korcsmáros, T., 2013, In : Unknown Journal. 7, 1 p.

Research output: Contribution to journalArticle

93 Citations (Scopus)

Signalogs: Orthology-based identification of novel signaling pathway components in three metazoans

Korcsmáros, T., Szalay, M. S., Rovó, P., Palotai, R., Fazekas, D., Lenti, K., FarkasIllé, I. J., Csermely, P. & Vellai, T., Jan 1 2011, In : PloS one. 6, 5, e19240.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Speciation in Chlamydia: Genomewide Phylogenetic Analyses Identified a Reliable Set of Acquired Genes

Ortutay, C., Gáspári, Z., Tóth, G., Jáger, E., Vida, G., Orosz, L. & Vellai, T., Dec 1 2003, In : Journal of Molecular Evolution. 57, 6, p. 672-680 9 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Starvation-response may not involve Atg 1-dependent autophagy induction in non-unikont parasites

Földvári-Nagy, L., Ari, E., Csermely, P., Korcsmáros, T. & Vellai, T., Apr 1 2015, In : Scientific reports. 4, 5829.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Suppression of AMPK/aak-2 by NRF2/SKN-1 downregulates autophagy during prolonged oxidative stress

Kosztelnik, M., Kurucz, A., Papp, D., Jones, E., Sigmond, T., Barna, J., Traka, M. H., Lorincz, T., Szarka, A., Banhegyi, G., Vellai, T., Korcsmaros, T. & Kapuy, O., Jan 1 2019, In : FASEB Journal. 33, 2, p. 2372-2387 16 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

systems-level feedbacks of NRF2 controlling autophagy upon oxidative stress response

Kapuy, O., Papp, D., Vellai, T., Bánhegyi, G. & Korcsmáros, T., Mar 2018, In : Antioxidants. 7, 3, 39.

Research output: Contribution to journalArticle

Open Access
13 Citations (Scopus)
Open Access
4 Citations (Scopus)
12 Citations (Scopus)

The Caenorhabditis elegans ortholog of C21orf80, a potential new protein O-fucosyltransferase, is required for normal development

Menzel, O., Vellai, T., Takacs-Vellai, K., Reymond, A., Mueller, F., Antonarakis, S. E. & Guipponi, M., Aug 1 2004, In : Genomics. 84, 2, p. 320-330 11 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

The human ABCB6 protein is the functional homologue of HMT-1 proteins mediating cadmium detoxification

Rakvács, Z., Kucsma, N., Gera, M., Igriczi, B., Kiss, K., Barna, J., Kovács, D., Vellai, T., Bencs, L., Reisecker, J. M., Szoboszlai, N. & Szakács, G., Jan 1 2019, In : Cellular and Molecular Life Sciences.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

The maintenance of sex in bacteria is ensured by its potential to reload genes

Szöllosi, G. J., Derényi, I. & Vellai, T., Dec 1 2006, In : Genetics. 174, 4, p. 2173-2180 8 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

The mechanism of ageing: Primary role of transposable elements in genome disintegration

Sturm, Á., Ivics, Z. & Vellai, T., May 1 2015, In : Cellular and Molecular Life Sciences. 72, 10, p. 1839-1847 9 p., 1896.

Research output: Contribution to journalArticle

21 Citations (Scopus)

The NM23-H1/H2 homolog NDK-1 is required for full activation of Ras signaling in C. elegans

Masoudi, N., Fancsalszky, L., Pourkarimi, E., Vellai, T., Alexa, A., Reményi, A., Gartner, A., Mehta, A. & Takács-Vellai, K., Aug 15 2013, In : Development (Cambridge). 140, 16, p. 3486-3495 10 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

The regulation of aging: does autophagy underlie longevity?

Vellai, T., Takács-Vellai, K., Sass, M. & Klionsky, D. J., Oct 1 2009, In : Trends in Cell Biology. 19, 10, p. 487-494 8 p.

Research output: Contribution to journalArticle

96 Citations (Scopus)