• 1197 Citations
  • 16 h-Index
19922017

Research output per year

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Research Output

  • 1197 Citations
  • 16 h-Index
  • 26 Article
  • 2 Comment/debate
  • 2 Short survey
  • 2 Review article
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Article
2017

In vitro imaging and quantification of the drug targeting efficiency of fluorescently labeled GnRH analogues

Murányi, J., Varga, A., Gurbi, B., Gyulavári, P., Mező, G. & Vántus, T., Mar 21 2017, In : Journal of Visualized Experiments. 2017, 121, e55529.

Research output: Contribution to journalArticle

2016

Novel compounds reducing IRS-1 serine phosphorylation for treatment of diabetes

Simon-Szabó, L., Kokas, M., Greff, Z., Boros, S., Bánhegyi, P., Zsákai, L., Szántai-Kis, C., Vántus, T., Mandl, J., Bánhegyi, G., Vályi-Nagy, I., Őrfi, L., Ullrich, A., Csala, M. & Kéri, G., Jan 15 2016, In : Bioorganic and Medicinal Chemistry Letters. 26, 2, p. 424-428 5 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Synthesis, characterization and systematic comparison of FITC-labelled GnRH-I, -II and -III analogues on various tumour cells

Murányi, J., Gyulavári, P., Varga, A., Bökönyi, G., Tanai, H., Vántus, T., Pap, D., Ludányi, K., Mező, G. & Kéri, G., Aug 1 2016, In : Journal of Peptide Science. p. 552-560 9 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
2015

Targeting vascular endothelial growth factor receptor 2 and protein kinase D1 related pathways by a multiple kinase inhibitor in angiogenesis and inflammation related processes in vitro

Varga, A., Gyulavári, P., Greff, Z., Futosi, K., Németh, T., Simon-Szabó, L., Kerekes, K., Szántai-Kis, C., Brauswetter, D., Kokas, M., Borbély, G., Erdei, A., Mócsai, A., Kéri, G. & Vántus, T., Apr 14 2015, In : PloS one. 10, 4, e0124234.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2014

Discovery and biological evaluation of novel dual EGFR/c-Met inhibitors

Szokol, B., Gyulavári, P., Kurkó, I., Baska, F., Szántai-Kis, C., Greff, Z., Orfi, Z., Peták, I., Pénzes, K., Torka, R., Ullrich, A., Orfi, L., Vántus, T. & Kéri, G., Apr 10 2014, In : ACS Medicinal Chemistry Letters. 5, 4, p. 298-303 6 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2012

Dasatinib inhibits proinflammatory functions of mature human neutrophils

Futosi, K., Németh, T., Pick, R., Vántus, T., Walzog, B. & Mócsai, A., May 24 2012, In : Blood. 119, 21, p. 4981-4991 11 p.

Research output: Contribution to journalArticle

55 Citations (Scopus)

Optimization of important early ADME(T) parameters of NADPH oxidase-4 inhibitor molecules

Borbély, G., Huszár, M., Varga, A., Futosi, K., Mócsai, A., Orfi, L., Idei, M., Mandl, J., Kéri, G. & Vántus, T., Mar 2012, In : Medicinal Chemistry. 8, 2, p. 174-181 8 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2010

Comparative characterization of experimental and calculated lipophilicity and anti-tumour activity of isochromanone derivatives

Huszár, M., Varga, A., Horváth, A., Loránd, T., Agócs, A., Idei, M., Mandl, J., Vántus, T. & Kéri, G., Feb 1 2010, In : Current medicinal chemistry. 17, 4, p. 321-333 13 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Nanoparticles based on PLGA: Poloxamer blends for the delivery of proangiogenic growth factors

D'Angelo, I., Garcia-Fuentes, M., Parajó, Y., Welle, A., Vántus, T., Horváth, A., Bökönyi, G., Kéri, G. & Alonso, M. J., Oct 4 2010, In : Molecular Pharmaceutics. 7, 5, p. 1724-1733 10 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)

PLGA:poloxamer blend micro- and nanoparticles as controlled release systems for synthetic proangiogenic factors

Parajó, Y., d'Angelo, I., Horváth, A., Vantus, T., György, K., Welle, A., Garcia-Fuentes, M. & Alonso, M. J., Dec 23 2010, In : European Journal of Pharmaceutical Sciences. 41, 5, p. 644-649 6 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Small-molecule inhibitors of NADPH oxidase 4

Borbély, G., Szabadkai, I., Horváth, Z., Markó, P., Varga, Z., Breza, N., Baska, F., Vántus, T., Huszár, M., Geiszt, M., Hunyady, L., Buday, L., Örfi, L. & Kéri, G., Sep 23 2010, In : Journal of Medicinal Chemistry. 53, 18, p. 6758-6762 5 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)
2009

Detection of hydrogen peroxide by lactoperoxidase-mediated dityrosine formation

Donkó, Á., Orient, A., Szabó, P. T., Németh, G., Vántus, T., Kéri, G., Örfi, L., Hunyady, L., Buday, L. & Geiszt, M., Jul 20 2009, In : Free Radical Research. 43, 5, p. 440-445 6 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2008

New cyclic somatostatin analogues containing a pyrazinone ring: Importance of Tyr for antiproliferative activity

Miyazaki, A., Tsuda, Y., Fukushima, S., Yokoi, T., Vántus, T., Bökönyi, G., Szabó, E., Horváth, A., Kéri, G. & Okada, Y., Dec 1 2008, In : Bioorganic and Medicinal Chemistry Letters. 18, 23, p. 6199-6201 3 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Synthesis of somatostatin analogues containing C-terminal adamantane and their antiproliferative properties

Miyazaki, A., Tsuda, Y., Fukushima, S., Yokoi, T., Vántus, T., Bökönyi, G., Szabó, E., Horváth, A., Kéri, G. & Okada, Y., Aug 28 2008, In : Journal of Medicinal Chemistry. 51, 16, p. 5121-5124 4 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)
2004

Doxorubicin-induced activation of protein kinase D1 through caspase-mediated proteolytic cleavage: Identification of two cleavage sites by microsequencing

Vántus, T., Vertommen, D., Saelens, X., Rykx, A., De Kimpe, L., Vancauwenbergh, S., Mikhalap, S., Waelkens, E., Kéri, G., Seufferlein, T., Vandenabeele, P., Rider, M. H., Vandenheede, J. R. & Van Lint, J., Jun 1 2004, In : Cellular Signalling. 16, 6, p. 703-709 7 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)
2001

The antitumor somatostatin analogue TT-232 induces cell cycle arrest through PKCδ and c-Src

Steták, A., Vántus, T., Csermely, P., Kéri, G., Lankenau, A. & Ullrich, A., Jan 1 2001, In : Biochemical and biophysical research communications. 285, 2, p. 483-488 6 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)

The somatostatin analogue TT-232 induces apoptosis in A431 cells - Sustained activation of stress-activated kinases and inhibition of signalling to extracellular signal-regulated kinases

Vántus, T., Kéri, G., Krivickiene, Z., Valius, M., Steták, A., Keppens, S., Csermely, P., Bauer, P. I., Bökönyi, G., Declercq, W., Vandenabeele, P., Merlevede, W. & Vandenheede, J. R., Sep 11 2001, In : Cellular Signalling. 13, 10, p. 717-725 9 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)
2000
Open Access
237 Citations (Scopus)
1999

JNK-SAPK activation by platelet-derived growth factor in A431 cells requires both the phospholipase C-γ and the phosphatidylinositol 3-kinase signaling pathways of the receptor

Assefa, Z., Valius, M., Vántus, T., Agostinis, P., Merlevede, W. & Vandenheede, J. R., Aug 11 1999, In : Biochemical and biophysical research communications. 261, 3, p. 641-645 5 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)
1997
1 Citation (Scopus)
1996

A tumor-selective somatostatin analog (TT-232) with strong in vitro and in vivo antitumor activity

Kéri, G., Érchegyi, J., Horváth, A., Mezõ, I., Idei, M., Vántus, T., Balogh, Á., Vadász, Z., Bökönyi, G., Seprõdi, J., Teplán, I., Csuka, O., Tejeda, M., Gaál, D., Szegedi, Z., Szende, B., Roze, C., Kalthoff, H. & Ullrich, A., Oct 29 1996, In : Proceedings of the National Academy of Sciences of the United States of America. 93, 22, p. 12513-12518 6 p.

Research output: Contribution to journalArticle

96 Citations (Scopus)
1995
25 Citations (Scopus)
1993

Novel somatostatin analogs with tyrosine kinase inhibitory and antitumor activity

Kéri, G., Mezõ, I., Horváth, A., Vadász, Z., Balogh, Á., Idei, M., Vántus, T., Teplán, I., Mák, M., Horváth, J., Pál, K. & Csuka, O., Mar 15 1993, In : Biochemical and biophysical research communications. 191, 2, p. 681-687 7 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)

Self-similarity of Mn(II)-induced trypsin activity oscillations. Experimental evidence

Vajda, T., Almási, F. & Vántus, T., Nov 1 1993, In : Journal of Inorganic Biochemistry. 52, 2, p. 131-138 8 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Structure-activity relationship studies of novel somatostatin analogs with antitumor activity

Keri, G., Mezo, I., Vadasz, Z., Horvath, A., Idei, M., Vantus, T., Balogh, A., Bokonyi, G., Bajor, T., Teplan, I., Tamas, J., Mak, M., Horvath, J. & Csuka, O., Sep 1 1993, In : Peptide research. 6, 5, p. 281-288 8 p.

Research output: Contribution to journalArticle

50 Citations (Scopus)
1992

Novel antitumor peptide hormones and their effect on signal transduction

Kéri, G., Balogh, Á., Horváth, A., Mező, I., Vadász, Z., Bökönyi, G., Bajor, T., Vántus, T., Teplán, I., Horváth, J., Csuka, O. & Nicholson, R. I., Sep 1992, In : Journal of Steroid Biochemistry and Molecular Biology. 43, 1-3, p. 105-110 6 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)