• 1017 Citations
  • 21 h-Index
20052020

Research output per year

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Research Output

  • 1017 Citations
  • 21 h-Index
  • 41 Article
  • 5 Review article
  • 1 Chapter
2020

Detection of Molecular Signatures of Homologous Recombination Deficiency in Prostate Cancer with or without BRCA1/2 Mutations

Sztupinszki, Z., Diossy, M., Krzystanek, M., Borcsok, J., Pomerantz, M. M., Tisza, V., Spisak, S., Rusz, O., Csabai, I., Freedman, M. L. & Szallasi, Z., Jun 1 2020, In : Clinical Cancer Research. 26, 11, p. 2673-2680 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2019

En bloc release of MVB-like small extracellular vesicle clusters by colorectal carcinoma cells

Valcz, G., Buzás, E. I., Kittel, Á., Krenács, T., Visnovitz, T., Spisák, S., Török, G., Homolya, L., Zsigrai, S., Kiszler, G., Antalffy, G., Pálóczi, K., Szállási, Z., Szabó, V., Sebestyén, A., Solymosi, N., Kalmár, A., Dede, K., Lőrincz, P., Tulassay, Z. & 2 others, Igaz, P. & Molnár, B., Jan 1 2019, In : Journal of Extracellular Vesicles. 8, 1, 1596668.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Limitations of high throughput methods for miRNA expression profiles in non-functioning pituitary adenomas

Darvasi, O., Szabo, P. M., Nemeth, K., Szabo, K., Spisak, S., Liko, I., Czirjak, S., Racz, K., Igaz, P., Patocs, A. & Butz, H., Jan 15 2019, In : Pathology and Oncology Research. 25, 1, p. 169-182 14 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2018

A Somatically Acquired Enhancer of the Androgen Receptor Is a Noncoding Driver in Advanced Prostate Cancer

Takeda, D. Y., Spisák, S., Seo, J. H., Bell, C., O'Connor, E., Korthauer, K., Ribli, D., Csabai, I., Solymosi, N., Szállási, Z., Stillman, D. R., Cejas, P., Qiu, X., Long, H. W., Tisza, V., Nuzzo, P. V., Rohanizadegan, M., Pomerantz, M. M., Hahn, W. C. & Freedman, M. L., Jul 12 2018, In : Cell. 174, 2, p. 422-432.e13

Research output: Contribution to journalArticle

44 Citations (Scopus)
2017

Colorectal adenoma and cancer detection based on altered methylation pattern of SFRP1, SFRP2, SDC2, and PRIMA1 in plasma samples

Barták, B. K., Kalmár, A., Péterfia, B., Patai, Á. V., Galamb, O., Valcz, G., Spisák, S., Wichmann, B., Nagy, Z. B., Tóth, K., Tulassay, Z., Igaz, P. & Molnár, B., Sep 2 2017, In : Epigenetics. 12, 9, p. 751-763 13 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)
2016

Aberrant DNA methylation of WNT pathway genes in the development and progression of CIMP-negative colorectal cancer

Galamb, O., Kalmár, A., Péterfia, B., Csabai, I., Bodor, A., Ribli, D., Krenács, T., Patai, Á. V., Wichmann, B., Barták, B. K., Tóth, K., Valcz, G., Spisák, S., Tulassay, Z. & Molnár, B., Jun 30 2016, (Accepted/In press) In : Epigenetics. p. 1-15 15 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)

Exosomes in colorectal carcinoma formation: ALIX under the magnifying glass

Valcz, G., Galamb, O., Krenács, T., Spisák, S., Kalmár, A., Patai, Á. V., Wichmann, B., Dede, K., Tulassay, Z. & Molnár, B., May 6 2016, (Accepted/In press) In : Modern Pathology.

Research output: Contribution to journalArticle

12 Citations (Scopus)
2015
9 Citations (Scopus)

CAUSEL: An epigenome- and genome-editing pipeline for establishing function of noncoding GWAS variants

Spisák, S., Lawrenson, K., Fu, Y., Csabai, I., Cottman, R. T., Seo, J. H., Haiman, C., Han, Y., Lenci, R., Li, Q., Tisza, V., Szállási, Z., Herbert, Z. T., Chabot, M., Pomerantz, M., Solymosi, N., Gayther, S. A., Joung, J. K. & Freedman, M. L., Nov 1 2015, In : Nature medicine. 21, 11, p. 1357-1363 7 p.

Research output: Contribution to journalArticle

49 Citations (Scopus)

Cell free DNA of tumor origin induces a 'metastatic' expression profile in HT-29 cancer cell line

Furi, I., Kalmár, A., Wichmann, B., Spisák, S., Schöller, A., Barták, B., Tulassay, Z. & Molnár, B., Jul 2 2015, In : PloS one. 10, 7, e0131699.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Chronic hyperglycemia induces trans-differentiation of human pancreatic stellate cells and enhances the malignant molecular communication with human pancreatic cancer cells

Kiss, K., Baghy, K., Spisák, S., Szanyi, S., Tulassay, Z., Zalatnai, A., Löhr, J. M., Jesenofsky, R., Kovalszky, I. & Firneisz, G., May 26 2015, In : PloS one. 10, 5, e0128059.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Comprehensive DNA methylation analysis reveals a common ten-gene methylation signature in colorectal adenomas and carcinomas

Patai, Á. V., Valcz, G., Hollósi, P., Kalmár, A., Péterfia, B., Patai, Á., Wichmann, B., Spisák, S., Barták, B. K., Leiszter, K., Tóth, K., Sipos, F., Kovalszky, I., Péter, Z., Miheller, P., Tulassay, Z. & Molnár, B., Aug 20 2015, In : PloS one. 10, 8, e0133836.

Research output: Contribution to journalArticle

30 Citations (Scopus)

DNA hypermethylation and decreased mRNA expression of MAL, PRIMA1, PTGDR and SFRP1 in colorectal adenoma and cancer

Kalmár, A., Péterfia, B., Hollósi, P., Galamb, O., Spisák, S., Wichmann, B., Bodor, A., Tóth, K., Patai, Á. V., Valcz, G., Nagy, Z. B., Kubák, V., Tulassay, Z., Kovalszky, I. & Molnár, B., Oct 19 2015, In : BMC cancer. 15, 1, 736.

Research output: Contribution to journalArticle

33 Citations (Scopus)

Gene-expression analysis of a colorectal cancer-specific discriminatory transcript set on formalin-fixed, paraffin-embedded (FFPE) tissue samples

Kalmár, A., Wichmann, B., Galamb, O., Spisák, S., Tóth, K., Leiszter, K., Nielsen, B. S., Barták, B. K., Tulassay, Z. & Molnár, B., Jul 25 2015, In : Diagnostic Pathology. 10, 1, 126.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Upregulation of heat shock proteins and the promotion of damage-associated molecular pattern signals in a colorectal cancer model by modulated electrohyperthermia

Andocs, G., Meggyeshazi, N., Balogh, L., Spisak, S., Maros, M. E., Balla, P., Kiszner, G., Teleki, I., Kovago, C. & Krenacs, T., Jan 1 2015, In : Cell Stress and Chaperones. 20, 1, p. 37-46 10 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)
2014

Intravenous Administration of a Single-Dose Free-Circulating DNA of Colitic Origin Improves Severe Murine DSS-Colitis

Sipos, F., Műzes, G., Fűri, I., Spisák, S., Wichmann, B., Germann, T. M., Constantinovits, M., Krenács, T., Tulassay, Z. & Molnár, B., Jan 1 2014, In : Pathology and Oncology Research. 20, 4, p. 867-877 11 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
16 Citations (Scopus)

Myofibroblast-derived SFRP1 as potential inhibitor of colorectal carcinoma field effect

Valcz, G., Patai, Á. V., Kalmár, A., Péterfia, B., Furi, I., Wichmann, B., Muzes, G., Sipos, F., Krenács, T., Mihály, E., Spisák, S., Molnár, B. & Tulassay, Z., Nov 18 2014, In : PloS one. 9, 11, 106143.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Preconditioning with Intravenous Colitic Cell-Free DNA Prevents DSS-Colitis by Altering TLR9-Associated Gene Expression Profile

Műzes, G., Sipos, F., Fűri, I., Constantinovits, M., Spisák, S., Wichmann, B., Valcz, G., Tulassay, Z. & Molnár, B., Nov 19 2014, In : Digestive Diseases and Sciences. 59, 12, p. 2935-2946 12 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2013

Aberrant septin 9 DNA methylation in colorectal cancer is restricted to a single CpG island

Wasserkort, R., Kalmar, A., Valcz, G., Spisak, S., Krispin, M., Toth, K., Tulassay, Z., Sledziewski, A. Z. & Molnar, B., Aug 30 2013, In : BMC cancer. 13, 398.

Research output: Contribution to journalArticle

69 Citations (Scopus)
7 Citations (Scopus)

Complete Genes May Pass from Food to Human Blood

Spisák, S., Solymosi, N., Ittzés, P., Bodor, A., Kondor, D., Vattay, G., Barták, B. K., Sipos, F., Galamb, O., Tulassay, Z., Szállási, Z., Rasmussen, S., Sicheritz-Ponten, T., Brunak, S., Molnár, B. & Csabai, I., Jul 30 2013, In : PloS one. 8, 7, e69805.

Research output: Contribution to journalArticle

29 Citations (Scopus)

From chemical genomics to chemical proteomics: The power of microarray technology

Spisák, S. & Guttman, A., Jan 1 2013, Chemical Genomics and Proteomics, Second Edition. CRC Press, p. 81-121 41 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)
26 Citations (Scopus)

Mikro-RNS-expresszió vizsgálata adenoid cysticus emlo-és nyálmirigy-carcinomákban

Translated title of the contribution: MicroRNA-profiling in breast-and salivary gland-derived adenoid cystic carcinomasKiss, O., Tokés, A. M., Spisák, S., Szilágyi, A., Lippai, N., Szász, A. M. & Kulka, J., Jun 1 2013, In : Orvosi hetilap. 154, 25, p. 963-968 6 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2012

Dysplasia-Carcinoma Transition Specific Transcripts in Colonic Biopsy Samples

Galamb, O., Wichmann, B., Sipos, F., Spisák, S., Krenács, T., Tóth, K., Leiszter, K., Kalmár, A., Tulassay, Z. & Molnár, B., Nov 14 2012, In : PloS one. 7, 11, e48547.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Genome-Wide Screening of Genes Regulated by DNA Methylation in Colon Cancer Development

Spisák, S., Kalmár, A., Galamb, O., Wichmann, B., Sipos, F., Péterfia, B., Csabai, I., Kovalszky, I., Semsey, S., Tulassay, Z. & Molnár, B., Oct 1 2012, In : PloS one. 7, 10, e46215.

Research output: Contribution to journalArticle

28 Citations (Scopus)
2011

The influence of methylated septin 9 gene on RNA and protein level in colorectal cancer

Tóth, K., Galamb, O., Spisák, S., Wichmann, B., Sipos, F., Valcz, G., Leiszter, K., Molnár, B. & Tulassay, Z., Sep 1 2011, In : Pathology and Oncology Research. 17, 3, p. 503-509 7 p.

Research output: Contribution to journalArticle

47 Citations (Scopus)
2010
13 Citations (Scopus)

Metilációs szabályozás alatt álló gének azonosítása lézerrel kimetszett vastagbéldaganat-sejtekben az adenoma-carcinoma sorrend vizsgálata során

Translated title of the contribution: Identification of methylation related genes from Lacer Capture Microdissected colon samples during investigation of adenoma-carcinoma sequenceSpisák, S., Kalmár, A., Galamb, O., Sipos, F., Wichmann, B., Molnár, B. & Tulassay, Z., May 1 2010, In : Orvosi hetilap. 151, 20, p. 805-814 10 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Reversal of gene expression changes in the colorectal normal-adenoma pathway by NS398 selective COX2 inhibitor

Galamb, O., Spisák, S., Sipos, F., Tóth, K., Solymosi, N., Wichmann, B., Krenács, T., Valcz, G., Tulassay, Z. & Molnár, B., Feb 1 2010, In : British journal of cancer. 102, 4, p. 765-773 9 p.

Research output: Contribution to journalArticle

51 Citations (Scopus)

The possible role of isolated lymphoid follicles in colonic mucosal repair

Sipos, F., Műzes, G., Galamb, O., Spisák, S., Krenács, T., Tóth, K., Tulassay, Z. & Molnár, B., Mar 2010, In : Pathology and Oncology Research. 16, 1, p. 11-18 8 p.

Research output: Contribution to journalReview article

15 Citations (Scopus)
2009

Biomedical applications of protein microarrays

Spisák, S. & Guttman, A., Sep 29 2009, In : Current medicinal chemistry. 16, 22, p. 2806-2815 10 p.

Research output: Contribution to journalReview article

31 Citations (Scopus)
7 Citations (Scopus)
43 Citations (Scopus)

Szabad DNS-alapú vastagbéldaganat-szurés perifériás vérbol: a metilált szeptin-9 génmarker lehetoségei

Translated title of the contribution: Free circulating DNA based colorectal cancer screening from peripheral blood: The possibility of the methylated septin 9 gene markerTóth, K., Galamb, O., Spisák, S., Wichmann, B., Sipos, F., Leiszter, K., Molnár, J., Molnár, B. & Tulassay, Z., May 1 2009, In : Orvosi hetilap. 150, 21, p. 969-977 9 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Vastagbéldaganatok ellenanyag-microarray-vel kimutatott, TMA-validált progressziós markerei

Translated title of the contribution: Tissue microarray (TMA) validated progression markers in colorectal cancer using antibody microarraysSpisák, S., Galamb, B., Wichmann, B., Sipos, F., Galamb, O., Solymosi, N., Nemes, B., Tulassay, Z. & Molnár, B., Aug 1 2009, In : Orvosi hetilap. 150, 34, p. 1607-1613 7 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2008
59 Citations (Scopus)
25 Citations (Scopus)
Open Access
67 Citations (Scopus)

Vastagbél-biopszia funkcionális mRNS-expressziós vizsgálata és osztályozása általános cDNS microarray technikával

Translated title of the contribution: Functional mRNA expression analysis and classification of colonic biopsy samples using overall cDNA microarray techniqueGalamb, O., Sipos, F., Dinya, E., Spisák, S., Somorácz, Á., Molnár, B. & Tulassay, Z., Feb 3 2008, In : Orvosi hetilap. 149, 5, p. 219-232 14 p.

Research output: Contribution to journalArticle

2007
19 Citations (Scopus)

Fehérjechipek elméleti alapjai és alkalmazási lehetoségük az orvosi diagnosztikában és kutatásban

Translated title of the contribution: Theoretical foundations of protein chips and their possible use in medical research and diagnosticsSpisák, S., Molnár, B., Galamb, O., Sipos, F. & Tulassay, Z., Aug 12 2007, In : Orvosi hetilap. 148, 32, p. 1511-1520 10 p.

Research output: Contribution to journalReview article

2 Citations (Scopus)

Protein microchips in biomedicine and biomarker discovery

Spisak, S., Tulassay, Z., Molnar, B. & Guttman, A., Dec 1 2007, In : ELECTROPHORESIS. 28, 23, p. 4261-4273 13 p.

Research output: Contribution to journalReview article

59 Citations (Scopus)

Vastagbél-adenoma, vastagbélrák és IBD-specifikus génexpressziós mintázatok meghatározása teljes genomszintu oligonukleotid microarray-rendszerrel

Translated title of the contribution: Identification of colorectal cancer, adenoma, and inflammatory bowel disease specific gene expression patterns using whole genomic oligonucleotide microarray systemGalamb, O., Gyorffy, B., Sipos, F., Spisák, S., Németh, A. M., Miheller, P., Dinya, E., Molnár, B. & Tulassay, Z., Nov 4 2007, In : Orvosi hetilap. 148, 44, p. 2067-2079 13 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2006
Open Access
18 Citations (Scopus)
2005

A p53 gén és fehérje 2005-ben: Új eredmények, ígéretes lehetoségek

Translated title of the contribution: The p53 gene and protein in 2005: New results, promising opportunitiesSzoke, D., Sipos, F., Spisák, S., Molnár, B. & Tulassay, Z., Dec 1 2005, In : Orvosi hetilap. 146, 30, p. 1587-1594 8 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)