• 651 Citations
  • 14 h-Index
19962019
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Research Output 1996 2019

  • 651 Citations
  • 14 h-Index
  • 87 Article
  • 1 Review article
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Article
2019

Antispasmodic activity of prenylated phenolic compounds from the root bark of morus nigra

Zoofishan, Z., Kúsz, N., Csorba, A., Tóth, G., Hajagos-Tóth, J., Kothencz, A., Gáspár, R. & Hunyadi, A., Jan 1 2019, In : Molecules. 24, 13, 2497.

Research output: Contribution to journalArticle

Open Access
Morus
Parasympatholytics
smooth muscle
medicine
muscular function

A-tocopherol potentiates the cervical resistance decreasing effects of COX inhibitors in pregnant rats: The putative role of cyclooxygenase-2 inhibition

Kothencz, A., Hajagos-Tóth, J., Szucs, K. F., Schaffer, A. & Gáspár, R., Feb 1 2019, In : Journal of Pharmacology and Experimental Therapeutics. 368, 2, p. 292-298 7 p.

Research output: Contribution to journalArticle

Tocopherols
Cyclooxygenase Inhibitors
Cyclooxygenase 2
Prostaglandin-Endoperoxide Synthases
Diclofenac
4 Citations (Scopus)

Hesperidin improves the follicular development in 3D culture of isolated preantral ovarian follicles of mice

Shoorei, H., Banimohammad, M., Kebria, M. M., Afshar, M., Taheri, M. M. H., Shokoohi, M., Farashah, M. S. G., Eftekharzadeh, M., Akhiani, O., Gáspár, R. & Pazoki-Toroudi, H., Jan 1 2019, In : Experimental Biology and Medicine.

Research output: Contribution to journalArticle

Hesperidin
Ovarian Follicle
Fertilization in Vitro
Embryonic Development
Ovary
1 Citation (Scopus)
Cervical Ripening
rho-Associated Kinases
Simvastatin
Parturition
rhoA GTP-Binding Protein

Significance of transient receptor potential vanilloid 4 and aquaporin 5 co-expression in the rat uterus at term

Ducza, E., Csányi, A., Szőke, É., Pohóczky, K., Hajagos-Tóth, J., Kothencz, A., Tiszai, Z. & Gáspár, R., Oct 2019, In : Heliyon. 5, 10, e02697.

Research output: Contribution to journalArticle

Open Access
Aquaporin 5
TRPV Cation Channels
Uterus
Uterine Contraction
Pregnancy

Transformation of Meloxicam containing nanosuspension into surfactant-free solid compositions to increase the product stability and drug bioavailability for rapid analgesia

Bartos, C., Ambrus, R., Katona, G., Sovány, T., Gáspár, R., Márki, Á., Ducza, E., Ivanov, A., Tömösi, F., Janáky, T. & Szabó-Révész, P., Jan 1 2019, In : Drug Design, Development and Therapy. 13, p. 4007-4020 14 p.

Research output: Contribution to journalArticle

Open Access
meloxicam
Drug Stability
Surface-Active Agents
Analgesia
Biological Availability
2018
1 Citation (Scopus)

Alpha-tocopherol succinate increases cyclooxygenase-2 activity: Tissue-specific action in pregnant rat uterus in vitro

Kothencz, A., Hajagos-Tóth, J., Csányi, A. & Gáspár, R., Jan 1 2018, In : Life Sciences. 192, p. 199-204 6 p.

Research output: Contribution to journalArticle

Tocopherols
alpha-Tocopherol
Cyclooxygenase 2
Prostaglandin-Endoperoxide Synthases
Uterus

Anti-inflammatory activity of melampyrum barbatum and isolation of iridoid and flavonoid compounds

Háznagy-Radnai, E., Fási, L., Wéber, E., Pinke, G., Király, G., Sztojkov-Ivanov, A., Gáspár, R. & Hohmann, J., Jan 1 2018, In : Natural Product Communications. 13, 3, p. 235-236 2 p.

Research output: Contribution to journalArticle

Melampyrum
anti-inflammatory activity
Flavonoids
Anti-Inflammatory Agents
flavonoids
1 Citation (Scopus)

Detection of stress and the effects of central nervous system depressants by gastrointestinal smooth muscle electromyography in wakeful rats

Szűcs, K. F., Grosz, G., Süle, M., Sztojkov-Ivanov, A., Ducza, E., Márki, A., Kothencz, A., Balogh, L. & Gáspár, R., Jul 15 2018, In : Life Sciences. 205, p. 1-8 8 p.

Research output: Contribution to journalArticle

Central Nervous System Depressants
Electromyography
Smooth Muscle
Muscle
Gastrointestinal Tract
1 Citation (Scopus)

Effects of different antibiotics on the uterine contraction and the expression of aquaporin 5 in term pregnant rat

Csányi, A., Hajagos-Tóth, J., Kothencz, A., Gáspár, R. & Ducza, E., Oct 1 2018, In : Reproductive Toxicology. 81, p. 64-70 7 p.

Research output: Contribution to journalArticle

Aquaporin 5
Fosfomycin
Uterine Contraction
Amoxicillin
Oxytocin
rho-Associated Kinases
Rats
Uterine Contraction
Derivatives
Phosphorylation
2 Citations (Scopus)

Investigation of absorption routes of meloxicam and its salt form from intranasal delivery systems

Bartos, C., Ambrus, R., Kovács, A., Gáspár, R., Sztojkov-Ivanov, A., Márki, A., Janáky, T., T m si, F., Kecskeméti, G. & Szabó-Révész, P., Jan 1 2018, In : Molecules. 23, 4, 784.

Research output: Contribution to journalArticle

meloxicam
Nose
sprayers
Brain
delivery

The effect of increased NaCl intake on rat brain endogenous μ-opioid receptor signalling

Dadam, F., Zádor, F., Caeiro, X., Szűcs, E., Erdei, A., Samavati, R., Gáspár, R., Borsodi, A. & Vivas, L., Apr 1 2018, In : Journal of Neuroendocrinology. 30, 4, e12585.

Research output: Contribution to journalArticle

Opioid Receptors
Sodium
GTP-Binding Proteins
Brain
Preoptic Area
2017
4 Citations (Scopus)
Labor Onset
Uterine Contraction
rho-Associated Kinases
Pregnancy
Uterus
2 Citations (Scopus)

Characterization of [3H] oxymorphone binding sites in mouse brain: Quantitative autoradiography in opioid receptor knockout mice

Yoo, J. H., Borsodi, A., Tóth, G., Benyhe, S., Gáspár, R., Matifas, A., Kieffer, B. L., Metaxas, A., Kitchen, I. & Bailey, A., Mar 16 2017, In : Neuroscience Letters. 643, p. 16-21 6 p.

Research output: Contribution to journalArticle

Oxymorphone
Opioid Receptors
Autoradiography
Knockout Mice
Binding Sites
3 Citations (Scopus)

Herbal laxatives and antiemetics in pregnancy

Samavati, R., Ducza, E., Hajagos-Tóth, J. & Gáspár, R., Sep 1 2017, In : Reproductive Toxicology. 72, p. 153-158 6 p.

Research output: Contribution to journalArticle

Laxatives
Antiemetics
Ginger
Pregnancy
Nausea
1 Citation (Scopus)

Identification of myoelectric signals of pregnant rat uterus: New method to detect myometrial contraction

Szucs, K. F., Grosz, G., Süle, M., Nagy, A., Tiszai, Z., Samavati, R. & Gáspár, R., Apr 1 2017, In : Croatian Medical Journal. 58, 2, p. 141-148 8 p.

Research output: Contribution to journalArticle

Uterine Contraction
Myometrium
Uterus
Terbutaline
Electrodes
2 Citations (Scopus)
Kynurenic Acid
Opioid Receptors
N-Methyl-D-Aspartate Receptors
GTP-Binding Proteins
Dizocilpine Maleate
5 Citations (Scopus)

Obesity in pregnancy: A novel concept on the roles of adipokines in uterine contractility

Hajagos-Tóth, J., Ducza, E., Samavati, R., Vari, S. G. & Gáspár, R., Apr 1 2017, In : Croatian Medical Journal. 58, 2, p. 96-104 9 p.

Research output: Contribution to journalArticle

2016
3 Citations (Scopus)
Power spectrum
Smooth Muscle
Muscle
Gastrointestinal Tract
Rats
23 Citations (Scopus)

Development of ibuprofen-loaded nanostructured lipid carrier-based gels: Characterization and investigation of in vitro and in vivo penetration through the skin

Sütő, B., Berkó, S., Kozma, G., Kukovecz, Á., Budai-Szucs, M., Erös, G., Kemény, L., Sztojkov-Ivanov, A., Gáspár, R. & Csányi, E., Mar 30 2016, In : International Journal of Nanomedicine. 11, p. 1201-1212 12 p.

Research output: Contribution to journalArticle

Ibuprofen
Lipids
Skin
Gels
Permeation
7 Citations (Scopus)

Effect of solubility enhancement on nasal absorption of meloxicam

Horváth, T., Ambrus, R., Völgyi, G., Budai-Szűcs, M., Márki, Á., Sipos, P., Bartos, C., Seres, A. B., Sztojkov-Ivanov, A., Takács-Novák, K., Csányi, E., Gáspár, R. & Szabó-Révész, P., Dec 1 2016, In : European Journal of Pharmaceutical Sciences. 95, p. 96-102 7 p.

Research output: Contribution to journalArticle

meloxicam
Solubility
Potassium
Nose
Anti-Inflammatory Agents
5 Citations (Scopus)

Electroporation-delivered transdermal neostigmine in rats: Equivalent action to intravenous administration

Berkó, S., Szűcs, K. F., Balázs, B., Csányi, E., Varju, G., Sztojkov-Ivanov, A., Budai-Szűcs, M., Bóta, J. & Gáspár, R., May 19 2016, In : Drug Design, Development and Therapy. 10, p. 1695-1701 7 p.

Research output: Contribution to journalArticle

Neostigmine
Electroporation
Intravenous Administration
Skin
High Pressure Liquid Chromatography
2 Citations (Scopus)

The effects of estrogen on the α2-adrenergic receptor subtypes in rat uterine function in late pregnancy in vitro

Hajagos-Tóth, J., Bóta, J., Ducza, E., Csányi, A., Tiszai, Z., Borsodi, A., Samavati, R., Benyhe, S. & Gáspár, R., 2016, In : Croatian Medical Journal. 57, 2, p. 100-109 10 p.

Research output: Contribution to journalArticle

spiroxatrine
Adrenergic Receptors
Estrogens
Pregnancy
Estradiol
8 Citations (Scopus)

The effects of female sexual hormones on the expression of aquaporin 5 in the late-pregnant rat uterus

Csányi, A., Bóta, J., Falkay, G., Gáspár, R. & Ducza, E., Aug 22 2016, In : International Journal of Molecular Sciences. 17, 8, 1300.

Research output: Contribution to journalArticle

Aquaporin 5
uterus
hormones
Hormones
rats
3 Citations (Scopus)

The effects of progesterone on the alpha2-adrenergic receptor subtypes in late-pregnant uterine contractions in vitro

Hajagos-Tóth, J., Bóta, J., Ducza, E., Samavati, R., Borsodi, A., Benyhe, S. & Gáspár, R., Jun 14 2016, In : Reproductive Biology and Endocrinology. 14, 1, 33.

Research output: Contribution to journalArticle

Uterine Contraction
spiroxatrine
Adrenergic Receptors
Progesterone
Norepinephrine
2015
2 Citations (Scopus)
Tocolytic Agents
KATP Channels
Adrenergic Agonists
Myometrium
Pregnancy
5 Citations (Scopus)

Effects of d- and l-limonene on the pregnant rat myometrium in vitro

Hajagos-Tóth, J., Hódi, Á., Seres, A. B. & Gáspár, R., 2015, In : Croatian Medical Journal. 56, 5, p. 431-438 8 p.

Research output: Contribution to journalArticle

Myometrium
Uterine Contraction
Cyclic AMP
Pyruvaldehyde
Nifedipine

Effects of Nociceptin and Nocistatin on Uterine Contraction

Gáspár, R., Deák, B. H., Klukovits, A., Ducza, E. & Tekes, K., 2015, In : Vitamins and Hormones. 97, p. 223-240 18 p.

Research output: Contribution to journalArticle

Uterine Contraction
Myometrium
Pain Perception
Calcitonin Gene-Related Peptide
Naloxone
15 Citations (Scopus)

Study of sodium hyaluronate-based intranasal formulations containing micro- or nanosized meloxicam particles

Bartos, C., Ambrus, R., Sípos, P., Budai-Szucs, M., Csányi, E., Gáspár, R., Márki, A., Seres, A. B., Sztojkov-Ivanov, A., Horváth, T. & Szabó-Révész, P., Jul 6 2015, In : International Journal of Pharmaceutics. 491, 1-2, p. 198-207 10 p.

Research output: Contribution to journalArticle

meloxicam
Hyaluronic Acid
Particle Size
Area Under Curve
Electronic Nose
6 Citations (Scopus)

The effects of female sexual hormones on the expression and function of α1A- and α1D-adrenoceptor subtypes in the late-pregnant rat myometrium

Bóta, J., Hajagos-Tóth, J., Ducza, E., Samavati, R., Borsodi, A., Benyhe, S. & Gáspár, R., Dec 15 2015, In : European Journal of Pharmacology. 769, p. 177-184 8 p.

Research output: Contribution to journalArticle

Myometrium
Adrenergic Receptors
Hormones
Progesterone
Norepinephrine
2014
5 Citations (Scopus)

Androgenic effect of honeybee drone milk in castrated rats: Roles of methyl palmitate and methyl oleate

Seres, A. B., Ducza, E., Báthori, M., Hunyadi, A., Béni, Z., Dékány, M., Hajagos-Tóth, J., Verli, J. & Gáspár, R., Apr 28 2014, In : Journal of Ethnopharmacology. 153, 2, p. 446-453 8 p.

Research output: Contribution to journalArticle

Milk
Androgens
Testosterone
Proteins
methyl palmitate
1 Citation (Scopus)

A nyers heretej gesztagén hatásainak vizsgálata patkányban

Translated title of the contribution: Investigation of gestagenic effect of raw drone milk in ratsSeres, A., Ducza, E. & Gáspár, R., 2014, In : Acta Pharmaceutica Hungarica. 84, 2, p. 77-81 5 p.

Research output: Contribution to journalArticle

Progestins
Milk
Spironolactone
Calcitonin Receptors
Pregnancy Maintenance
11 Citations (Scopus)

Oxytocin regulates the expression of aquaporin 5 in the late-pregnant rat uterus

Ducza, E., Seres, A. B., Hajagos-Tóth, J., Falkay, G. & Gáspár, R., 2014, In : Molecular Reproduction and Development. 81, 6, p. 524-530 7 p.

Research output: Contribution to journalArticle

Aquaporin 5
Oxytocin
Uterus
Pregnancy
Aquaporins

Partial agonistic property of new isolated natural compounds

Ahmed, A. A. E., Gáspár, R., Márki, A., Mudawi, M. M. E. & Falkay, G., 2014, In : Journal of Chemical and Pharmaceutical Research. 6, 3, p. 1294-1298 5 p.

Research output: Contribution to journalArticle

Terbutaline
Adrenergic Receptors
Uterus
In Vitro Techniques
2 Citations (Scopus)

R(+)limonén hatása a β-adrenerg jelátvitelre a simaizomzatban: az oxidatív stressz index jelentosége

Translated title of the contribution: The effect of R(+) limonene on β-adrenerg signaling: The significance of oxidative stress indexÁgnes, H., Földesi, I., Judit, H. T., Eszter, D. & Gáspár, R., 2014, In : Acta Pharmaceutica Hungarica. 84, 3, p. 111-119 9 p.

Research output: Contribution to journalArticle

Terbutaline
Oxidative Stress
Myometrium
Antioxidants
estradiol valerate
7 Citations (Scopus)

Tocopherol inhibits the relaxing effect of terbutaline in the respiratory and reproductive tracts of the rat: The role of the oxidative stress index

Hódi, Á., Földesi, I., Ducza, E., Hajagos-Tóth, J., Seres, A. B., Klukovits, A. & Gáspár, R., Jun 6 2014, In : Life Sciences. 105, 1-2, p. 48-55 8 p.

Research output: Contribution to journalArticle

Terbutaline
Oxidative stress
Tocopherols
Respiratory System
Rats
2013
17 Citations (Scopus)

Calcium channel blockers as tocolytics: Principles of their actions, adverse effects and therapeutic combinations

Gáspár, R. & Hajagos-Tóth, J., 2013, In : Pharmaceuticals. 6, 6, p. 689-699 11 p.

Research output: Contribution to journalArticle

Tocolytic Agents
Tocolysis
Calcium Channel Blockers
Therapeutic Uses
Oxytocin
27 Citations (Scopus)

In vitro and in vivo characterization of meloxicam nanoparticles designed for nasal administration

Kürti, L., Gáspár, R., Márki, A., Kápolna, E., Bocsik, A., Veszelka, S., Bartos, C., Ambrus, R., Vastag, M., Deli, M. & Szabó-Révész, P., 2013, In : European Journal of Pharmaceutical Sciences. 50, 1, p. 86-92 7 p.

Research output: Contribution to journalArticle

meloxicam
Intranasal Administration
Nanoparticles
Nose
Area Under Curve
6 Citations (Scopus)
Calcium-Activated Potassium Channels
Uterine Contraction
Calcitonin Gene-Related Peptide
Uterus
Capsaicin
5 Citations (Scopus)

Raw drone milk of honeybees elicits uterotrophic effect in rats: Evidence for estrogenic activity

Seres, A. B., Ducza, E., Báthori, M., Hunyadi, A., Béni, Z., Dékány, M. & Gáspár, R., May 1 2013, In : Journal of Medicinal Food. 16, 5, p. 404-409 6 p.

Research output: Contribution to journalArticle

Milk
Estrogens
Acids
Medicine in Literature
Hormones
11 Citations (Scopus)

Uterus-relaxing effect of β2-agonists in combination with phosphodiesterase inhibitors: Studies on pregnant rat in vivo and on pregnant human myometrium in vitro

Verli, J., Klukovits, A., Kormányos, Z., Hajagos-Tóth, J., Ducza, E., Seres, A. B., Falkay, G. & Gáspár, R., Jan 2013, In : The journal of obstetrics and gynaecology research. 39, 1, p. 31-39 9 p.

Research output: Contribution to journalArticle

Rolipram
Phosphodiesterase Inhibitors
Myometrium
Terbutaline
Uterus
2011

A KATP csatorna szulfonilurea alegységeinek ontogenezise a terhes patkány miometriumban

Translated title of the contribution: Ontogeny of sulphonylurea-binding regulatory submits of KATP channels in the pregnant rat myometriumLovász, N., Ducza, E., Gáspár, R. & Falkay, G., 2011, In : Acta Pharmaceutica Hungarica. 81, 3, p. 101-107 7 p.

Research output: Contribution to journalArticle

KATP Channels
Sulfonylurea Receptors
Myometrium
Pinacidil
Diazoxide
1 Citation (Scopus)

In silico and in vitro pharmacological investigations of a natural alkaloid

Ahmed, A. A. E., Márki, A., Gáspár, R., Vasas, A., Mudawi, M. M. E., Jójárt, B., Minorics, R., Hohmann, J. & Falkay, G., 2011, (Accepted/In press) In : Medicinal Chemistry Research. p. 1-8 8 p.

Research output: Contribution to journalArticle

Terbutaline
Alkaloids
Computer Simulation
Adrenergic Receptors
Pharmacology
7 Citations (Scopus)

Ontogeny of sulfonylurea-binding regulatory subunits of K ATP channels in the pregnant rat myometrium

Lovasz, N., Ducza, E., Gáspár, R. & Falkay, G., Jul 2011, In : Reproduction. 142, 1, p. 175-181 7 p.

Research output: Contribution to journalArticle

Myometrium
Sulfonylurea Receptors
Adenosine Triphosphate
Pinacidil
Diazoxide
69 Citations (Scopus)

Small molecule AKAP-Protein Kinase A (PKA) interaction disruptors that activate PKA interfere with compartmentalized cAMP signaling in cardiac myocytes

Christian, F., Szaszák, M., Friedl, S., Drewianka, S., Lorenz, D., Goncalves, A., Furkert, J., Vargas, C., Schmieder, P., Götz, F., Zühlke, K., Moutty, M., Göttert, H., Joshi, M., Reif, B., Haase, H., Morano, I., Grossmann, S., Klukovits, A., Verli, J. & 16 others, Gáspár, R., Noack, C., Bergmann, M., Kass, R., Hampel, K., Kashin, D., Genieser, H. G., Herberg, F. W., Willoughby, D., Cooper, D. M. F., Baillie, G. S., Houslay, M. D., Von Kries, J. P., Zimmermann, B., Rosenthal, W. & Klussmann, E., Mar 18 2011, In : Journal of Biological Chemistry. 286, 11, p. 9079-9096 18 p.

Research output: Contribution to journalArticle

Cyclic AMP-Dependent Protein Kinases
Cardiac Myocytes
Protein Kinases
Phosphotransferases
Application programming interfaces (API)
7 Citations (Scopus)

β 2-Adrenergic activity of 6-methoxykaempferol-3-O-glucoside on rat uterus: In vitro and in silico studies

Ahmed, A. A. E., Márki, A., Gáspár, R., Vasas, A., Mudawi, M. M. E., Verli, J., Jójárt, B., Hohmann, J. & Falkay, G., Sep 30 2011, In : European Journal of Pharmacology. 667, 1-3, p. 348-354 7 p.

Research output: Contribution to journalArticle

Computer Simulation
Adrenergic Agents
Uterus
Adrenergic Receptors
Terbutaline
2010
4 Citations (Scopus)

Improving the relaxing effect of terbutaline with phosphodiesterase inhibitors: Studies on pregnant rat uteri in vitro

Klukovits, A., Verli, J., Falkay, G. & Gáspár, R., Dec 18 2010, In : Life Sciences. 87, 23-26, p. 733-737 5 p.

Research output: Contribution to journalArticle

Rolipram
Terbutaline
Phosphodiesterase Inhibitors
Uterus
Rats
2 Citations (Scopus)

Nifedipin miometrium relaxálo hatásának vizsgálata terbutalin és K+-csatorna gátlók jelenlétében in vitro

Translated title of the contribution: Investigation of uterus-relaxing effects of nifedipine in the presence of terbutaline and K+-channel blockersHajagos-Tóth, J., Kormányos, Z., Falkay, G., Pál, A. & Gáspár, R., 2010, In : Acta Pharmaceutica Hungarica. 80, 3, p. 109-114 6 p.

Research output: Contribution to journalArticle

Terbutaline
Nifedipine
Uterus
Uterine Contraction
Baths
15 Citations (Scopus)

Nociceptin inhibits uterine contractions in term-pregnant rats by signaling through multiple pathways

Klukovits, A., Tekes, K., Gündüz Çinar, Ö., Benyhe, S., Borsodi, A., Deák, B. H., Hajagos-Tóth, J., Verli, J., Falkay, G. & Gáspár, R., 2010, In : Biology of Reproduction. 83, 1, p. 36-41 6 p.

Research output: Contribution to journalArticle

Uterine Contraction
Naloxone
Tetraethylammonium
Pertussis Toxin
GTP-Binding Proteins