• 6953 Citations
  • 34 h-Index
1990 …2016

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

  • 6953 Citations
  • 34 h-Index
  • 66 Article
  • 5 Review article
  • 2 Comment/debate
  • 1 Short survey

Activation of calcium current in voltage‐clamped rat glomerulosa cells by potassium ions.

Várnai, P., Osipenko, O. N., Vizi, E. S. & Spät, A., Feb 15 1995, In : The Journal of Physiology. 483, 1, p. 67-78 12 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Activation of STIM1-Orai1 involves an intramolecular switching mechanism

Korzeniowski, M. K., Manjarrés, I. M., Varnai, P. & Balla, T., Nov 16 2010, In : Science Signaling. 3, 148, ra82.

Research output: Contribution to journalArticle

148 Citations (Scopus)

Active Arf6 recruits ARNO/cytohesin GEFs to the PM by binding their PH domains

Cohen, L. A., Honda, A., Varnai, P., Brown, F. D., Balla, T. & Donaldson, J. G., Jun 1 2007, In : Molecular Biology of the Cell. 18, 6, p. 2244-2253 10 p.

Research output: Contribution to journalArticle

152 Citations (Scopus)
18 Citations (Scopus)

Acute depletion of plasma membrane phosphatidylinositol 4,5-bisphosphate impairs specific steps in endocytosis of the G-protein-coupled receptor

Tóth, D. J., Tóth, J. T., Gulyás, G., Balla, A., Balla, T., Hunyady, L. & VáRnai, P., May 1 2012, In : Journal of cell science. 125, 9, p. 2185-2197 13 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)
100 Citations (Scopus)

Allosteric interactions within the AT 1 angiotensin receptor homodimer: Role of the conserved DRY motif

Szalai, B., Barkai, L., Turu, G., Szidonya, L., Várnai, P. & Hunyady, L., Aug 15 2012, In : Biochemical Pharmacology. 84, 4, p. 477-485 9 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)

Altered agonist sensitivity of a mutant V2 receptor suggests a novel therapeutic strategy for nephrogenic diabetes insipidus

Erdélyi, L. S., Balla, A., Patócs, A., Tóth, M., Várnai, P. & Hunyady, L., May 2014, In : Molecular Endocrinology. 28, 5, p. 634-643 10 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Angiotensin II inhibits K+-induced Ca2+ signal generation in rat adrenal glomerulosa cells

Balla, T., Hollo, Z., Varnai, P. & Spat, A., Jan 1 1991, In : Biochemical Journal. 273, 2, p. 399-404 6 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)
170 Citations (Scopus)

AT1 receptor blocker-insensitive mutant AT1A angiotensin receptors reveal the presence of G protein-independent signaling in C9 cells

Szidonya, L., Süpeki, K., Karip, E., Turu, G., Várnai, P., Clark, A. J. L. & Hunyady, L., May 15 2007, In : Biochemical Pharmacology. 73, 10, p. 1582-1592 11 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
17 Citations (Scopus)

Calcium current activated by potassium ions in voltage-clamped rat hippocampal pyramidal neurones

Deák, F., Nagy, G., Vârnai, P., Madarász, E. & Spät, A., May 1 1998, In : Journal of Physiology. 508, 3, p. 735-745 11 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Calcium entry is regulated by Zn2+ in relation to extracellular ionic environment in human airway epithelial cells

Hargitai, D., Pataki, Á., Raffai, G., Füzi, M., Dankó, T., Csernoch, L., Várnai, P., Szigeti, G. P. & Zsembery, Á., Jan 31 2010, In : Respiratory Physiology and Neurobiology. 170, 1, p. 67-75 9 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Calcium transport across the inner mitochondrial membrane: Molecular mechanisms and pharmacology

Csordás, G., Várnai, P., Golenár, T., Sheu, S. S. & Hajnóczky, G., Apr 28 2012, In : Molecular and Cellular Endocrinology. 353, 1-2, p. 109-113 5 p.

Research output: Contribution to journalReview article

33 Citations (Scopus)

Chaperone-mediated coupling of endoplasmic reticulum and mitochondrial Ca2+ channels

Szabadkai, G., Bianchi, K., Várnai, P., De Stefani, D., Wieckowski, M. R., Cavagna, D., Nagy, A. I., Balla, T. & Rizzuto, R., Dec 18 2006, In : Journal of Cell Biology. 175, 6, p. 901-911 11 p.

Research output: Contribution to journalArticle

612 Citations (Scopus)
15 Citations (Scopus)

c-Met must translocate to the nucleus to initiate calcium signals

Gomes, D. A., Rodrigues, M. A., Leite, M. F., Gomez, M. V., Varnai, P., Balla, T., Bennett, A. M. & Nathanson, M. H., Feb 15 2008, In : Journal of Biological Chemistry. 283, 7, p. 4344-4351 8 p.

Research output: Contribution to journalArticle

106 Citations (Scopus)

Control of calcium signal propagation to the mitochondria by inositol 1,4,5-trisphosphate-binding proteins

Lin, X., Várnai, P., Csordás, G., Balla, A., Nagai, T., Miyawaki, A., Balla, T. & Hajnóczky, G., Apr 1 2005, In : Journal of Biological Chemistry. 280, 13, p. 12820-12832 13 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

Correction: Improved methodical approach for quantitative BRET analysis of G protein coupled receptor dimerization

Szalai, B., Hoffmann, P., Prokop, S., Erdélyi, L., Várnai, P. & Hunyady, L., May 1 2016, In : PLoS One. 11, 5, e0156824.

Research output: Contribution to journalComment/debate

6 Citations (Scopus)

Dependence of STIM1/Orai1-mediated calcium entry on plasma membrane phosphoinositides

Korzeniowski, M. K., Popovic, M. A., Szentpetery, Z., Varnai, P., Stojilkovic, S. S. & Balla, T., Jul 31 2009, In : Journal of Biological Chemistry. 284, 31, p. 21027-21035 9 p.

Research output: Contribution to journalArticle

102 Citations (Scopus)

Distribution and Apoptotic Function of Outer Membrane Proteins Depend on Mitochondrial Fusion

Weaver, D., Eisner, V., Liu, X., Várnai, P., Hunyady, L., Gross, A. & Hajnóczky, G., Jun 5 2014, In : Molecular Cell. 54, 5, p. 870-878 9 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

Dopamine blocks T-type calcium channels in cultured rat adrenal

Osipenko, O. N., Várnai, P., Mike, A., Spät, A. & Vizi, E. S., Jan 1994, In : Endocrinology. 134, 1, p. 511-514 4 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Dual regulation of TRPV1 by phosphoinositides

Lukacs, V., Thyagarajan, B., Varnai, P., Balla, A., Balla, T. & Rohacs, T., Jun 27 2007, In : Journal of Neuroscience. 27, 26, p. 7070-7080 11 p.

Research output: Contribution to journalArticle

203 Citations (Scopus)
18 Citations (Scopus)

Electrophysiological study on the high K+ sensitivity of rat glomerulosa cells

Várnai, P., Petheö, G. L., Makara, J. K. & Spät, A., Feb 18 1998, In : Pflugers Archiv European Journal of Physiology. 435, 3, p. 429-431 3 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Endocytosis of the AT1A angiotensin receptor is independent of ubiquitylation of its cytoplasmic serine/threonine-rich region

Mihalik, B., Gáborik, Z., Várnai, P., Clark, A. J. L., Catt, K. J. & Hunyady, L., Jun 1 2003, In : International Journal of Biochemistry and Cell Biology. 35, 6, p. 992-1002 11 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Highly co‐operative Ca2+ activation of intermediate‐conductance K+ channels in granulocytes from a human cell line.

Varnai, P., Demaurex, N., Jaconi, M., Schlegel, W., Lew, D. P. & Krause, K. H., Dec 1 1993, In : The Journal of Physiology. 472, 1, p. 373-390 18 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

How accurately can we image inositol lipids in living cells?

Balla, T., Bondeva, T. & Várnai, P., Jul 1 2000, In : Trends in Pharmacological Sciences. 21, 7, p. 238-241 4 p.

Research output: Contribution to journalShort survey

113 Citations (Scopus)

Identification of Renox, an NAD(P)H oxidase in kidney

Geiszt, M., Kopp, J. B., Várnai, P. & Leto, T. L., Jul 5 2000, In : Proceedings of the National Academy of Sciences of the United States of America. 97, 14, p. 8010-8014 5 p.

Research output: Contribution to journalArticle

634 Citations (Scopus)

Imaging Interorganelle Contacts and Local Calcium Dynamics at the ER-Mitochondrial Interface

Csordás, G., Várnai, P., Golenár, T., Roy, S., Purkins, G., Schneider, T. G., Balla, T. & Hajnóczky, G., Jul 1 2010, In : Molecular Cell. 39, 1, p. 121-132 12 p.

Research output: Contribution to journalArticle

372 Citations (Scopus)

Improved methodical approach for quantitative BRET analysis of G protein coupled receptor dimerization

Szalai, B., Hoffmann, P., Prokop, S., Erdélyi, L., Várnai, P. & Hunyady, L., Oct 17 2014, In : PloS one. 9, 10, e109503.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Inositol lipid binding and membrane localization of isolated pleckstrin homology (PH) domains. Studies on the PH domains of phospholipase C δ1 and p130

Várnai, P., Lin, X., Lee, S. B., Tuymetova, G., Bondeva, T., Spät, A., Rhee, S. G., Czky, G. H. & Balla, T., Jul 26 2002, In : Journal of Biological Chemistry. 277, 30, p. 27412-27422 11 p.

Research output: Contribution to journalArticle

97 Citations (Scopus)

Interaction of Neuronal Calcium Sensor-1 (NCS-1) with Phosphatidylinositol 4-Kinase β Stimulates Lipid Kinase Activity and Affects Membrane Trafficking in COS-7 Cells

Zhao, X., Várnai, P., Tuymetova, G., Balla, A., Tóth, Z. E., Oker-Blom, C., Roder, J., Jeromin, A. & Balla, T., Oct 26 2001, In : Journal of Biological Chemistry. 276, 43, p. 40183-40189 7 p.

Research output: Contribution to journalArticle

114 Citations (Scopus)

Investigation of the fate of type I angiotensin receptor after biased activation

Szakadáti, G., Tóth, A. D., Oláh, I., Erdélyi, L. S., Balla, T., Várnai, P., Hunyady, L. & Balla, A., Jun 1 2015, In : Molecular pharmacology. 87, 6, p. 972-981 10 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Lenz-Majewski mutations in PTDSS1 affect phosphatidylinositol 4-phosphate metabolism at ER-PM and ER-golgi junctions

Sohn, M., Ivanova, P., Brown, H. A., Toth, D. J., Várnai, P., Kim, Y. J. & Balla, T., Apr 19 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 16, p. 4314-4319 6 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)

Live cell imaging of phosphoinositide dynamics with fluorescent protein domains

Várnai, P. & Balla, T., Aug 1 2006, In : Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1761, 8, p. 957-967 11 p.

Research output: Contribution to journalReview article

110 Citations (Scopus)

Live cell imaging of phosphoinositides with expressed inositide binding protein domains

Várnai, P. & Balla, T., Nov 1 2008, In : Methods. 46, 3, p. 167-176 10 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)

Maintenance of hormone-sensitive phosphoinositide pools in the plasma membrane requires phosphatidylinositol 4-kinase IIIα

Balla, A., Yeun, J. K., Varnai, P., Szentpetery, Z., Knight, Z., Shokat, K. M. & Balla, T., Feb 1 2008, In : Molecular Biology of the Cell. 19, 2, p. 711-721 11 p.

Research output: Contribution to journalArticle

121 Citations (Scopus)

Mapping of the localization of type 1 angiotensin receptor in membrane microdomains using bioluminescence resonance energy transfer-based sensors

Balla, A., Tóth, D. J., Soltész-Katona, E., Szakadáti, G., Erdélyi, L. S., Várnai, P. & Hunyady, L., Mar 16 2012, In : Journal of Biological Chemistry. 287, 12, p. 9090-9099 10 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Measurement of inositol 1,4,5-trisphosphate in living cells using an improved set of resonance energy transfer-based biosensors

Gulyás, G., Tóth, J. T., Tóth, D. J., Kurucz, I., Hunyady, L., Balla, T. & Várnai, P., May 1 2015, In : PloS one. 10, 5, e0125601.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Mechanisms of angiotensin II-mediated regulation of aldosterone synthase expression in H295R human adrenocortical and rat adrenal glomerulosa cells

Szekeres, M., Turu, G., Orient, A., Szalai, B., Süpeki, K., Cserzo, M., Várnai, P. & Hunyady, L., Apr 29 2009, In : Molecular and Cellular Endocrinology. 302, 2, p. 244-253 10 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Mitochondrial Ca2+ uptake with and without the formation of high-Ca2+ microdomains

Szanda, G., Koncz, P., Várnai, P. & Spät, A., Jan 1 2006, In : Cell Calcium. 40, 5-6, p. 527-537 11 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

Monitoring Agonist-induced Phospholipase C Activation in Live Cells by Fluorescence Resonance Energy Transfer

Van der Wal, J., Habets, R., Várnai, P., Balla, T. & Jalink, K., May 4 2001, In : Journal of Biological Chemistry. 276, 18, p. 15337-15344 8 p.

Research output: Contribution to journalArticle

201 Citations (Scopus)

Motifs of VDAC2 required for mitochondrial Bak import and tBid-induced apoptosis

Naghdi, S., Várnai, P. & Hajnóczky, G., Oct 13 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 41, p. E5590-E5599

Research output: Contribution to journalArticle

33 Citations (Scopus)

Mutation in the V2 vasopressin receptor gene, AVPR2, causes nephrogenic syndrome of inappropriate diuresis

Erdélyi, L. S., Mann, W. A., Morris-Rosendahl, D. J., Groß, U., Nagel, M., Várnai, P., Balla, A. & Hunyady, L., Nov 1 2015, In : Kidney International. 88, 5, p. 1070-1078 9 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Paracrine transactivation of the CB1 cannabinoid receptor by AT1 angiotensin and other Gq/11 protein-coupled receptors

Turu, G., Várnal, P., Gyombolai, P., Szidonya, L., Offertaler, L., Bagdy, G., Kunos, G. & Hunyady, L., Jun 19 2009, In : Journal of Biological Chemistry. 284, 25, p. 16914-16921 8 p.

Research output: Contribution to journalArticle

48 Citations (Scopus)
247 Citations (Scopus)
Open Access
92 Citations (Scopus)