• 6930 Citations
  • 34 h-Index
1990 …2016
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Research Output 1990 2016

  • 6930 Citations
  • 34 h-Index
  • 73 Article
  • 1 Comment/debate
1990
18 Citations (Scopus)
Zona Glomerulosa
Aldosterone
Potassium
1,4-dihydropyridine
Fura-2
3 Citations (Scopus)

The evaluation of safety drain after cholecystectomy.

Dubecz, S., Juhász, F., Bottlik, G. & Várnai, P., 1990, In : Acta Chirurgica Hungarica. 31, 4, p. 333-338 6 p.

Research output: Contribution to journalArticle

Cholecystectomy
Safety
Wounds and Injuries
Wound Infection
Gallbladder
1991
13 Citations (Scopus)

Angiotensin II inhibits K+-induced Ca2+ signal generation in rat adrenal glomerulosa cells

Balla, T., Hollo, Z., Várnai, P. & Spät, A., 1991, In : Biochemical Journal. 273, 2, p. 399-404 6 p.

Research output: Contribution to journalArticle

Zona Glomerulosa
Angiotensin II
Rats
Adrenocorticotropic Hormone
Aldosterone
22 Citations (Scopus)

Thapsigargin-induced increase in cytoplasmic Ca2+ concentration and aldosterone production in rat Adrenal glomerulosa cells: Interaction with potassium and angiotensin-II

Hajnóczky, G., Várnai, P., Holló, Z., Christensen, S. B., Balla, T., Enyedi, P. & Spät, A., May 1991, In : Endocrinology. 128, 5, p. 2639-2644 6 p.

Research output: Contribution to journalArticle

Zona Glomerulosa
Thapsigargin
Aldosterone
Cell Communication
Angiotensin II
1992
92 Citations (Scopus)
Zona Glomerulosa
Aldosterone
Oxidation-Reduction
Potassium
Nucleotides
21 Citations (Scopus)

Regulation of Ca2+ influx in myeloid cells: Role of plasma membrane potential, inositol phosphates, cytosolic free [Ca2+], and filling state of intracellular Ca2+ stores

Demaurex, N., Schlegel, W., Várnai, P., Mayr, G., Lew, D. P. & Krause, K. H., 1992, In : Journal of Clinical Investigation. 90, 3, p. 830-839 10 p.

Research output: Contribution to journalArticle

Inositol Phosphates
Myeloid Cells
Formyl Peptide Receptor
Membrane Potentials
Calcium-Transporting ATPases
31 Citations (Scopus)
Zona Glomerulosa
Aldosterone
Protein Kinase C
Potassium
Acetates
1993
24 Citations (Scopus)

Highly co-operative Ca2+ activation of intermediate conductance K+ channels in granulocytes from a human cell line

Várnai, P., Demaurex, N., Jaconi, M., Schlegel, W., Lew, D. P. & Krause, K. H., 1993, In : Journal of Physiology. 472, p. 373-390 18 p.

Research output: Contribution to journalArticle

Granulocytes
Charybdotoxin
Apamin
Cell Line
Ionophores
1994
20 Citations (Scopus)

Dopamine blocks T-type calcium channels in cultured rat adrenal glomerulosa cells

Osipenko, O. N., Várnai, P., Mike, A., Spät, A. & Vízi, E., Jan 1994, In : Endocrinology. 134, 1, p. 511-514 4 p.

Research output: Contribution to journalArticle

T-Type Calcium Channels
Zona Glomerulosa
Dopamine
Quinpirole
Sulpiride
1995
20 Citations (Scopus)

Activation of calcium current in voltage-clamped rat glomerulosa cells by potassium ions

Várnai, P., Osipenko, O. N., Vízi, E. & Spät, A., 1995, In : Journal of Physiology. 483, 1, p. 67-78 12 p.

Research output: Contribution to journalArticle

Potassium
Ions
Calcium
Nifedipine
T-Type Calcium Channels
1998
5 Citations (Scopus)

Calcium current activated by potassium ions in voltage-clamped rat hippocampal pyramidal neurones

Deák, F., Nagy, G., Várnai, P., Madarász, E. & Spät, A., May 1 1998, In : Journal of Physiology. 508, 3, p. 735-745 11 p.

Research output: Contribution to journalArticle

Pyramidal Cells
Potassium
Ions
Inwardly Rectifying Potassium Channel
Calcium
22 Citations (Scopus)

Electrophysiological study on the high K+ sensitivity of rat glomerulosa cells

Várnai, P., Petheö, G., Makara, J. K. & Spät, A., 1998, In : Pflugers Archiv European Journal of Physiology. 435, 3, p. 429-431 3 p.

Research output: Contribution to journalArticle

Rats
Clamping devices
Electric potential
Patch-Clamp Techniques
Chemical activation
25 Citations (Scopus)

Signaling events activated by angiotensin II receptors: What goes before and after the calcium signals

Balla, T., Várnai, P., Tian, Y. & Smith, R. D., 1998, In : Endocrine Research. 24, 3-4, p. 335-344 10 p.

Research output: Contribution to journalArticle

Angiotensin Receptors
Angiotensin II
Proto-Oncogene Proteins c-raf
Calcium
Mitogen-Activated Protein Kinase Kinases
593 Citations (Scopus)
Phosphatidylinositol 4,5-Diphosphate
Inositol
Phosphatidylinositols
Calcium
Fluorescent Dyes
51 Citations (Scopus)

Voltage dependent calcium channels in adrenal glomerulosa cells and in insulin producing cells

Horváth, A., Szabadkai, G., Várnai, P., Arányi, T., Wollheim, C. B., Spät, A. & Enyedi, P., Jan 1998, In : Cell Calcium. 23, 1, p. 33-42 10 p.

Research output: Contribution to journalArticle

Zona Glomerulosa
Calcium Channels
Insulin
Polymerase Chain Reaction
Restriction Mapping
1999
247 Citations (Scopus)
Phosphatidylinositol 3-Kinase
Cells
Association reactions
Membranes
NIH 3T3 Cells
10 Citations (Scopus)

Selective inhibition of potassium-stimulated rat adrenal glomerulosa cells by ruthenium red

Szabadkai, G., Várnai, P. & Enyedi, P., Jan 15 1999, In : Biochemical Pharmacology. 57, 2, p. 209-218 10 p.

Research output: Contribution to journalArticle

Zona Glomerulosa
Ruthenium Red
Rats
Potassium
Aldosterone
2000
113 Citations (Scopus)

How accurately can we image inositol lipids in living cells?

Balla, T., Bondeva, T. & Várnai, P., Jul 1 2000, In : Trends in Pharmacological Sciences. 21, 7, p. 238-241 4 p.

Research output: Contribution to journalArticle

Luminescent Proteins
Molecular Probes
Lipid bilayers
Phosphoproteins
Inositol
634 Citations (Scopus)

Identification of Renox, an NAD(P)H oxidase in kidney

Geiszt, M., Kopp, J. B., Várnai, P. & Leto, T. L., Jul 5 2000, In : Proceedings of the National Academy of Sciences of the United States of America. 97, 14, p. 8010-8014 5 p.

Research output: Contribution to journalArticle

Oxygen
Kidney
NADPH Oxidase
Superoxides
Reactive Oxygen Species
2001
114 Citations (Scopus)

Interaction of Neuronal Calcium Sensor-1 (NCS-1) with Phosphatidylinositol 4-Kinase β Stimulates Lipid Kinase Activity and Affects Membrane Trafficking in COS-7 Cells

Zhao, X., Várnai, P., Tuymetova, G., Balla, A., Tóth, Z., Oker-Blom, C., Roder, J., Jeromin, A. & Balla, T., Oct 26 2001, In : Journal of Biological Chemistry. 276, 43, p. 40183-40189 7 p.

Research output: Contribution to journalArticle

1-Phosphatidylinositol 4-Kinase
COS Cells
Phosphotransferases
Membranes
Lipids
201 Citations (Scopus)

Monitoring Agonist-induced Phospholipase C Activation in Live Cells by Fluorescence Resonance Energy Transfer

Van der Wal, J., Habets, R., Várnai, P., Balla, T. & Jalink, K., May 4 2001, In : Journal of Biological Chemistry. 276, 18, p. 15337-15344 8 p.

Research output: Contribution to journalArticle

Fluorescence Resonance Energy Transfer
Type C Phospholipases
Chemical activation
Cells
Monitoring
2002
97 Citations (Scopus)

Inositol lipid binding and membrane localization of isolated pleckstrin homology (PH) domains. Studies on the PH domains of phospholipase C δ1 and p130

Várnai, P., Lin, X., Lee, S. B., Tuymetova, G., Bondeva, T., Spät, A., Rhee, S. G., Czky, G. H. & Balla, T., Jul 26 2002, In : Journal of Biological Chemistry. 277, 30, p. 27412-27422 11 p.

Research output: Contribution to journalArticle

Type C Phospholipases
Inositol
Membrane Lipids
Green Fluorescent Proteins
Membranes
59 Citations (Scopus)

Structural determinants of Ras-Raf interaction analyzed in live cells

Bondeva, T., Balla, A., Várnai, P. & Balla, T., 2002, In : Molecular Biology of the Cell. 13, 7, p. 2323-2333 11 p.

Research output: Contribution to journalArticle

Green Fluorescent Proteins
Mitogen-Activated Protein Kinases
Cell Membrane
Cysteine
Membranes
112 Citations (Scopus)
Phosphatidylinositols
Proteins
Personnel Selection
Membranes
Calcium Signaling
2003
4 Citations (Scopus)

Endocytosis of the AT1A angiotensin receptor is independent of ubiquitylation of its cytoplasmic serine/threonine-rich region

Mihalik, B., Gáborik, Z., Várnai, P., Clark, A. J. L., Catt, K. J. & Hunyady, L., Jun 1 2003, In : International Journal of Biochemistry and Cell Biology. 35, 6, p. 992-1002 11 p.

Research output: Contribution to journalArticle

Angiotensin Receptors
Ubiquitination
Threonine
Endocytosis
Serine
2004
19 Citations (Scopus)

The pleckstrin homology domain of phosphoinositide-specific phospholipase Cδ4 is not a critical determinant of the membrane localization of the enzyme

Lee, S. B., Várnai, P., Balla, A., Jalink, K., Rhee, S. G. & Balla, T., Jun 4 2004, In : Journal of Biological Chemistry. 279, 23, p. 24362-24371 10 p.

Research output: Contribution to journalArticle

Phospholipases
Phosphatidylinositols
Membranes
Enzymes
Programmable logic controllers
2005
170 Citations (Scopus)
1-Phosphatidylinositol 4-Kinase
Cell Membrane
Down-Regulation
Cytoplasmic Vesicles
COS Cells
29 Citations (Scopus)

Control of calcium signal propagation to the mitochondria by inositol 1,4,5-trisphosphate-binding proteins

Lin, X., Várnai, P., Csordás, G., Balla, A., Nagai, T., Miyawaki, A., Balla, T. & Hajnóczky, G., Apr 1 2005, In : Journal of Biological Chemistry. 280, 13, p. 12820-12832 13 p.

Research output: Contribution to journalArticle

Inositol 1,4,5-Trisphosphate Receptors
Mitochondria
Inositol 1,4,5-Trisphosphate
Carrier Proteins
Calcium
36 Citations (Scopus)
Inositol 1,4,5-Trisphosphate Receptors
Ligands
Endoplasmic Reticulum
Nucleic Acid Regulatory Sequences
Second Messenger Systems
2006
603 Citations (Scopus)

Chaperone-mediated coupling of endoplasmic reticulum and mitochondrial Ca2+ channels

Szabadkai, G., Bianchi, K., Várnai, P., De Stefani, D., Wieckowski, M. R., Cavagna, D., Nagy, A. I., Balla, T. & Rizzuto, R., Dec 18 2006, In : Journal of Cell Biology. 175, 6, p. 901-911 11 p.

Research output: Contribution to journalArticle

Endoplasmic Reticulum
Voltage-Dependent Anion Channels
Inositol 1,4,5-Trisphosphate Receptors
Molecular Chaperones
Mitochondrial Membranes
110 Citations (Scopus)

Live cell imaging of phosphoinositide dynamics with fluorescent protein domains

Várnai, P. & Balla, T., Aug 2006, In : Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1761, 8, p. 957-967 11 p.

Research output: Contribution to journalArticle

Phosphatidylinositols
Inositol
Lipids
Membranes
Cell Fractionation
31 Citations (Scopus)

Mitochondrial Ca2+ uptake with and without the formation of high-Ca2+ microdomains

Szanda, G., Koncz, P., Várnai, P. & Spät, A., Nov 2006, In : Cell Calcium. 40, 5-6, p. 527-537 11 p.

Research output: Contribution to journalArticle

Reticulum
Mitochondria
Angiotensin II
Cell Membrane
Luteal Cells
251 Citations (Scopus)

Rapidly inducible changes in phosphatidylinositol 4,5-bisphosphate levels influence multiple regulatory functions of the lipid in intact living cells

Várnai, P., Thyagarajan, B., Rohacs, T. & Balla, T., Nov 6 2006, In : Journal of Cell Biology. 175, 3, p. 377-382 6 p.

Research output: Contribution to journalArticle

Phosphatidylinositols
phosphoinositide 5-phosphatase
Tacrolimus Binding Protein 1A
Phosphatidylinositol 4,5-Diphosphate
Cell Membrane
713 Citations (Scopus)

Structural and functional features and significance of the physical linkage between ER and mitochondria

Csordás, G., Renken, C., Várnai, P., Walter, L., Weaver, D., Buttle, K. F., Balla, T., Mannella, C. A. & Hajnóczky, G., Sep 25 2006, In : Journal of Cell Biology. 174, 7, p. 915-921 7 p.

Research output: Contribution to journalArticle

Endoplasmic Reticulum
Mitochondria
Cell Survival
Electron Microscope Tomography
Smooth Endoplasmic Reticulum
2007
152 Citations (Scopus)

Active Arf6 recruits ARNO/cytohesin GEFs to the PM by binding their PH domains

Cohen, L. A., Honda, A., Várnai, P., Brown, F. D., Balla, T. & Donaldson, J. G., Jun 2007, In : Molecular Biology of the Cell. 18, 6, p. 2244-2253 10 p.

Research output: Contribution to journalArticle

Guanosine Triphosphate
Cell Membrane
Guanine Nucleotide Exchange Factors
COS Cells
GTP Phosphohydrolases
10 Citations (Scopus)

AT1 receptor blocker-insensitive mutant AT1A angiotensin receptors reveal the presence of G protein-independent signaling in C9 cells

Szidonya, L., Süpeki, K., Karip, E., Turu, G., Várnai, P., Clark, A. J. L. & Hunyady, L., May 15 2007, In : Biochemical Pharmacology. 73, 10, p. 1582-1592 11 p.

Research output: Contribution to journalArticle

Angiotensin Receptors
GTP-Binding Proteins
Angiotensin II
Signal Transduction
Signal transduction
203 Citations (Scopus)

Dual regulation of TRPV1 by phosphoinositides

Lukacs, V., Thyagarajan, B., Várnai, P., Balla, A., Balla, T. & Rohacs, T., Jun 27 2007, In : Journal of Neuroscience. 27, 26, p. 7070-7080 11 p.

Research output: Contribution to journalArticle

Phosphatidylinositol 4,5-Diphosphate
Phosphatidylinositols
Capsaicin
Type C Phospholipases
vanilloid receptor subtype 1
66 Citations (Scopus)

Regulation of connexin43 gap junctional communication by phosphatidylinositol 4,5-bisphosphate

Van Zeijl, L., Ponsioen, B., Giepmans, B. N. G., Ariaens, A., Postma, F. R., Várnai, P., Balla, T., Divecha, N., Jalink, K. & Moolenaar, W. H., Jun 4 2007, In : Journal of Cell Biology. 177, 5, p. 881-891 11 p.

Research output: Contribution to journalArticle

Connexin 43
Phosphatidylinositol 4,5-Diphosphate
Phosphatidylinositols
Cell Communication
Phospholipases
40 Citations (Scopus)
Phosphatidylinositols
Visualization
Lipids
Membranes
Proteins
191 Citations (Scopus)
Cell membranes
Endoplasmic Reticulum
Visualization
Cell Membrane
Membranes
2008
15 Citations (Scopus)
Prolactin-Releasing Hormone
Tyrosine 3-Monooxygenase
Rats
Brain
Brain Stem
106 Citations (Scopus)

c-Met must translocate to the nucleus to initiate calcium signals

Gomes, D. A., Rodrigues, M. A., Leite, M. F., Gomez, M. V., Várnai, P., Balla, T., Bennett, A. M. & Nathanson, M. H., Feb 15 2008, In : Journal of Biological Chemistry. 283, 7, p. 4344-4351 8 p.

Research output: Contribution to journalArticle

Hepatocyte Growth Factor
Calcium
Cytoplasm
Karyopherins
Inositol 1,4,5-Trisphosphate
38 Citations (Scopus)

Live cell imaging of phosphoinositides with expressed inositide binding protein domains

Várnai, P. & Balla, T., Nov 2008, In : Methods. 46, 3, p. 167-176 10 p.

Research output: Contribution to journalArticle

Phosphatidylinositols
Carrier Proteins
Calcium Signaling
Inositol
Imaging techniques
120 Citations (Scopus)

Maintenance of hormone-sensitive phosphoinositide pools in the plasma membrane requires phosphatidylinositol 4-kinase IIIα

Balla, A., Yeun, J. K., Várnai, P., Szentpetery, Z., Knight, Z., Shokat, K. M. & Balla, T., Feb 2008, In : Molecular Biology of the Cell. 19, 2, p. 711-721 11 p.

Research output: Contribution to journalArticle

1-Phosphatidylinositol 4-Kinase
Phosphatidylinositols
Maintenance
Cell Membrane
Hormones
2009
102 Citations (Scopus)

Dependence of STIM1/Orai1-mediated calcium entry on plasma membrane phosphoinositides

Korzeniowski, M. K., Popovic, M. A., Szentpetery, Z., Várnai, P., Stojilkovic, S. S. & Balla, T., Jul 31 2009, In : Journal of Biological Chemistry. 284, 31, p. 21027-21035 9 p.

Research output: Contribution to journalArticle

Cell membranes
Phosphatidylinositols
Phosphatidylinositol 4,5-Diphosphate
Cell Membrane
1-Phosphatidylinositol 4-Kinase
22 Citations (Scopus)

Mechanisms of angiotensin II-mediated regulation of aldosterone synthase expression in H295R human adrenocortical and rat adrenal glomerulosa cells

Szekeres, M., Turu, G., Orient, A., Szalai, B., Süpeki, K., Cserzo, M., Várnai, P. & Hunyady, L., Apr 29 2009, In : Molecular and Cellular Endocrinology. 302, 2, p. 244-253 10 p.

Research output: Contribution to journalArticle

Cytochrome P-450 CYP11B2
Zona Glomerulosa
Angiotensin II
Rats
Calcium-Calmodulin-Dependent Protein Kinases
48 Citations (Scopus)

Paracrine transactivation of the CB1 cannabinoid receptor by AT1 angiotensin and other Gq/11 protein-coupled receptors

Turu, G., Várnai, P., Gyombolai, P., Szidonya, L., Offertaler, L., Bagdy, G., Kunos, G. & Hunyady, L., Jun 19 2009, In : Journal of Biological Chemistry. 284, 25, p. 16914-16921 8 p.

Research output: Contribution to journalArticle

Gq-G11 GTP-Binding Protein alpha Subunits
Cannabinoid Receptor CB1
Angiotensins
Transcriptional Activation
Endocannabinoids
123 Citations (Scopus)

STIM and Orai: the long-awaited constituents of store-operated calcium entry

Várnai, P., Hunyady, L. & Balla, T., Mar 2009, In : Trends in Pharmacological Sciences. 30, 3, p. 118-128 11 p.

Research output: Contribution to journalArticle

Calcium
Endoplasmic Reticulum
Molecules
Proteins
Cell membranes
51 Citations (Scopus)

Visualization of cellular phosphoinositide pools with GFP-fused protein-domains

Balla, T. & Várnai, P., 2009, In : Current Protocols in Cell Biology. SUPPL. 42

Research output: Contribution to journalArticle

Phosphatidylinositols
Membranes
Personnel Selection
Protein Domains
Eukaryotic Cells
2010
148 Citations (Scopus)

Activation of STIM1-Orai1 involves an intramolecular switching mechanism

Korzeniowski, M. K., Manjarrés, I. M., Várnai, P. & Balla, T., Nov 16 2010, In : Science Signaling. 3, 148, ra82.

Research output: Contribution to journalArticle

Chemical activation
Molecules
Mutation
Stromal Interaction Molecule 1
Clamping devices