• 651 Citations
  • 12 h-Index
1992 …2020

Research output per year

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Research Output

  • 651 Citations
  • 12 h-Index
  • 38 Article
  • 4 Review article
2020

Comparisons of in Vivo and in Vitro Opioid Effects of Newly Synthesized 14-Methoxycodeine-6-O-sulfate and Codeine-6-O-sulfate

Zádor, F., Mohammadzadeh, A., Balogh, M., Zádori, Z. S., Király, K., Barsi, S., Galambos, A. R., László, S. B., Hutka, B., Váradi, A., Hosztafi, S., Riba, P., Benyhe, S., Fürst, S. & Al-Khrasani, M., 2020, In : Molecules. 25, 6, 1370.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

On the role of peripheral sensory and gut mu opioid receptors: Peripheral analgesia and tolerance

Fürst, S., Zádori, Z. S., Zádor, F., Király, K., Balogh, M., László, S. B., Hutka, B., Mohammadzadeh, A., Calabrese, C., Galambos, A. R., Riba, P., Romualdi, P., Benyhe, S., Timár, J., Schmidhammer, H., Spetea, M. & Al-Khrasani, M., Jun 1 2020, In : Molecules. 25, 11, 2473.

Research output: Contribution to journalReview article

Open Access
2019

Efficacy-based perspective to overcome reduced opioid analgesia of advanced painful diabetic neuropathy in rats

Balogh, M., Zádor, F., Zádori, Z. S., Shaqura, M., Király, K., Mohammadzadeh, A., Varga, B., Lázár, B., Mousa, S. A., Hosztafi, S., Riba, P., Benyhe, S., Gyires, K., Schäfer, M., Fürst, S. & Al-Khrasani, M., 2019, In : Frontiers in Pharmacology. 10, APR, 347.

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)

Similarity and dissimilarity in antinociceptive effects of dipeptidyl-peptidase 4 inhibitors, Diprotin A and vildagliptin in rat inflammatory pain models following spinal administration

Balogh, M., Varga, B. K., Karádi, D. Á., Riba, P., Puskár, Z., Kozsurek, M., Al-Khrasani, M. & Király, K., Apr 2019, In : Brain Research Bulletin. 147, p. 78-85 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2018

The Peripheral Versus Central Antinociception of a Novel Opioid Agonist: Acute Inflammatory Pain in Rats

Balogh, M., Zádori, Z., Lázár, B., Karádi, D., László, S., Mousa, S. A., Hosztafi, S., Zádor, F., Riba, P., Schäfer, M., Fürst, S. & Al-Khrasani, M., May 3 2018, (Accepted/In press) In : Neurochemical Research. p. 1-8 8 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
2017

14-O-Methylmorphine: A Novel Selective Mu-Opioid Receptor Agonist with High Efficacy and Affinity

Zádor, F., Balogh, M., Váradi, A., Zádori, Z. S., Király, K., Szűcs, E., Varga, B., Lázár, B., Hosztafi, S., Riba, P., Benyhe, S., Fürst, S. & Al-Khrasani, M., Nov 5 2017, In : European Journal of Pharmacology. 814, p. 264-273 10 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

New opioid receptor antagonist: Naltrexone-14-O-sulfate synthesis and pharmacology

Zádor, F., Király, K., Váradi, A., Balogh, M., Fehér, Á., Kocsis, D., Erdei, A., Lackó, E., Zádori, Z., Hosztafi, S., Noszál, B., Riba, P., Benyhe, S., Fürst, S. & Al-Khrasani, M., Jan 1 2017, In : European Journal of Pharmacology. 809, p. 111-121 11 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2016

New morphine analogs produce peripheral antinociception within a certain dose range of their systemic administration

Lackó, E., Riba, P., Giricz, Z., Váradi, A., Cornic, L., Balogh, M., Király, K., Cseko, K., Mousa, S. A., Hosztafi, S., Schäfer, M., Zádori, Z. S., Helyes, Z., Ferdinándy, P., Fürst, S. & Al-Khrasani, M., Oct 2016, In : Journal of Pharmacology and Experimental Therapeutics. 359, 1, p. 171-181 11 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)
2015

A new potent analgesic agent with reduced liability to produce morphine tolerance

Kiraly, K., Caputi, F. F., Hanuska, A., Kató, E., Balogh, M., Köles, L., Palmisano, M., Riba, P., Hosztafi, S., Romualdi, P., Candeletti, S., Ferdinandy, P., Fürst, S. & Al-Khrasani, M., Aug 1 2015, In : Brain Research Bulletin. 117, p. 32-38 7 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)
2013

Az addikció kialakulásának új neurobiológiai mechanizmusai

Translated title of the contribution: New approach to the neurobiological mechanisms of addictionFurst, S., Riba, P. & Al-Khrasani, M., Dec 1 2013, In : Neuropsychopharmacologia Hungarica. 15, 4, p. 189-205 17 p.

Research output: Contribution to journalReview article

5 Citations (Scopus)

Functionalization of the carbonyl group in position 6 of morphinan-6-ones. development of novel 6-amino and 6-guanidino substituted 14-alkoxymorphinans

Schmidhammer, H., Spetea, M., Windisch, P., Schütz, J., Riba, P., Al-Khrasani, M. & Fürst, S., Dec 1 2013, In : Current pharmaceutical design. 19, 42, p. 7391-7399 9 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Peripheral antinociceptive efficacy and potency of a novel opioid compound 14-O-MeM6SU in comparison to known peptide and non-peptide opioid agonists in a rat model of inflammatory pain

Khalefa, B. I., Mousa, S. A., Shaqura, M., Lackó, E., Hosztafi, S., Riba, P., Schäfer, M., Ferdinandy, P., Fürst, S. & Al-Khrasani, M., Jun 4 2013, In : European Journal of Pharmacology. 713, 1-3, p. 54-57 4 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Spinal interaction between the highly selective μ agonist DAMGO and several δ opioid receptor ligands in naive and morphine-tolerant mice

Szentirmay, A. K., Király, K. P., Lenkey, N., Lackó, E., Al-Khrasani, M., Friedmann, T., Timár, J., Gyarmati, S., Tóth, G., Fürst, S. & Riba, P., Jan 1 2013, In : Brain Research Bulletin. 90, 1, p. 66-71 6 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Viselkedési vizsgálatok a gesztációs-laktációs ido{double acute}szakban morfn-kezelt patkányon

Translated title of the contribution: Behavioural studies during the gestational-lactation period in morphine treated ratsMelinda, S., Júlia, T., Pál, R., Király, K. P., Al-Khrasani, M., Zsuzsanna, G. & Zsuzsanna, F., Dec 1 2013, In : Neuropsychopharmacologia Hungarica. 15, 4, p. 239-251 13 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2012

A novel μ-opioid receptor ligand with high in vitro and in vivo agonist efficacy

Lackó, E., Váradi, A., Rapavi, R., Zádor, F., Riba, P., Benyhe, S., Borsodi, A., Hosztafi, S., Timár, J., Noszál, B., Fürst, S. & Al-Khrasani, M., Jan 1 2012, In : Current medicinal chemistry. 19, 27, p. 4699-4707 9 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)
9 Citations (Scopus)

The central versus peripheral antinociceptive effects of μ-opioid receptor agonists in the new model of rat visceral pain

Al-Khrasani, M., Lackó, E., Riba, P., Király, K., Sobor, M., Timár, J., Mousa, S., Schäfer, M. & Fürst, S., Feb 10 2012, In : Brain Research Bulletin. 87, 2-3, p. 238-243 6 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)
2011

Effects of opioid agonist and antagonist in dams exposed to morphine during the perinatal period

Sobor, M., Timar, J., Riba, P., Friedmann, T., Király, K. P., Gyarmati, S., Al-Khrasani, M. & Fürst, S., Jan 15 2011, In : Brain Research Bulletin. 84, 1, p. 53-60 8 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Synthesis and pharmacological activities of 6-glycine substituted 14-phenylpropoxymorphinans, a novel class of opioids with high opioid receptor affinities and antinociceptive potencies

Spetea, M., Windisch, P., Guo, Y., Bileviciute-Ljungar, I., Schütz, J., Asim, M. F., Berzetei-Gurske, I. P., Riba, P., Kiraly, K., Fürst, S., Al-Khrasani, M. & Schmidhammer, H., Feb 24 2011, In : Journal of Medicinal Chemistry. 54, 4, p. 980-988 9 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2010
7 Citations (Scopus)

Headache-type adverse effects of NO donors: Vasodilation and beyond

Bagdy, G., Riba, P., Kecskeméti, V., Chase, D. & Juhász, G., May 2010, In : British journal of pharmacology. 160, 1, p. 20-35 16 p.

Research output: Contribution to journalReview article

20 Citations (Scopus)

Idebenone: A guide to its use in Alzheimers disease, other age-related cognitive disorders and Friedreichs ataxia

Deary, I., Corley, J., Gow, A., Adkins, J., Noble, S., Gillis, J., Benfield, P., McTavish, D., Tsou, A., Friedman, L., Wilson, R., Boni, J., Maugeri, A., Zingali, G., Bergamasco, B., Scarzella, L., La Commare, P., Senin, U., Parnetti, L., Barbagallo-Sangiorgi, G. & 58 others, Weyer, G., Babej-Dlle, R., Hadler, D., Weyer, G., Erzigkeit, H., Hadler, D., Voronkova, K., Meleshkov, M., Guztmann, H., Khl, K., Hadler, D., Bergamasco, B., Villardita, C., Coppi, R., Marigliano, V., Abate, G., Barbagallo-Sangiorgi, G., Lingetti, M., Porfido, F., Ciarimboli, M., Nappi, G., Bono, G., Merlo, P., Kadota, I., Matsuoka, M., Shirakawa, S., Takauchi, S., Miyoshi, K., Di Prospero, N., Baker, A., Jeffries, N., Mariotti, C., Solari, A., Torta, D., Artuch, R., Aracil, A., Mas, A., Buyse, G., Mertens, L., Di Salvo, G., Hausse, A., Aggoun, Y., Bonnet, D., Pineda, M., Arpa, J., Montero, R., Riba, P., Pousset, F., Tanguy, M., Rinaldi, C., Tucci, T., Maione, S., Sival, D., De Marchie Sarvass, C., Brouwer, O., Trujillo-Martn, M., Serrano-Aguilar, P. & Monton-Alvarez, F., 2010, In : Drugs and Therapy Perspectives. 26, 2, p. 1-5 5 p.

Research output: Contribution to journalArticle

Novel approach to demonstrate high efficacy of μ opioids in the rat vas deferens: A simple model of predictive value

Riba, P., Friedmann, T., Király, K. P., Al-Khrasani, M., Sobor, M., Asim, M. F., Spetea, M., Schmidhammer, H. & Furst, S., Jan 15 2010, In : Brain Research Bulletin. 81, 1, p. 178-184 7 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Peri, pre and postnatal morphine exposure: Exposure-induced effects and sex differences in the behavioural consequences in rat offspring

Timár, J., Sobor, M., Király, K. P., Gyarmati, S., Riba, P., Al-Khrasani, M. & Fürst, S., Feb 1 2010, In : Behavioural Pharmacology. 21, 1, p. 58-68 11 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)
2007
30 Citations (Scopus)

Serotonin and epilepsy

Bagdy, G., Kecskemeti, V., Riba, P. & Jakus, R., Feb 1 2007, In : Journal of neurochemistry. 100, 4, p. 857-873 17 p.

Research output: Contribution to journalReview article

196 Citations (Scopus)
2006

Alterations in prodynorphin gene expression and dynorphin levels in different brain regions after chronic administration of 14-methoxymetopon and oxycodone-6-oxime

Király, K. P., Riba, P., D'Addario, C., Di Benedetto, M., Landuzzi, D., Candeletti, S., Romualdi, P. & Furst, S., Jul 31 2006, In : Brain Research Bulletin. 70, 3, p. 233-239 7 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)
2005

Norfluoxetine and fluoxetine have similar anticonvulsant and Ca 2+ channel blocking potencies

Kecskeméti, V., Rusznák, Z., Riba, P., Pál, B., Wagner, R., Harasztosi, C., Nánási, P. P. & Szûcs, G., Sep 30 2005, In : Brain Research Bulletin. 67, 1-2, p. 126-132 7 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

Peripheral versus central antinociceptive actions of 6-amino acid-substituted derivatives of 14-O-methyloxymorphone in acute and inflammatory pain in the rat

Fürst, S., Riba, P., Friedmann, T., Tímar, J., Al-Khrasani, M., Obara, I., Makuch, W., Spetea, M., Schütz, J., Przewlocki, R., Przewlocka, B. & Schmidhammer, H., Feb 2005, In : Journal of Pharmacology and Experimental Therapeutics. 312, 2, p. 609-618 10 p.

Research output: Contribution to journalArticle

60 Citations (Scopus)
2004

In vitro opioid activity profiles of 6-amino acid substituted derivatives of 14-O-methyloxymorphone

Spetea, M., Friedmann, T., Riba, P., Schütz, J., Wunder, G., Langer, T., Schmidhammer, H. & Fürst, S., Jan 12 2004, In : European Journal of Pharmacology. 483, 2-3, p. 301-308 8 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)
2003

Effects of structural modifications of N-CPM-normorphine derivatives on agonist and antagonist activities in isolated organs

Riba, P., Tóth, Z., Hosztafi, S., Friedman, T. & Fürst, S., 2003, In : Acta biologica Hungarica. 54, 2, p. 177-181 5 p.

Research output: Contribution to journalArticle

2002

[Dmt1]DALDA is highly selective and potent at μ opioid receptors, but is not cross-tolerant with systemic morphine

Riba, P., Ben, Y., Nguyen, T. M. D., Furst, S., Schiller, P. W. & Lee, N. M., Jan 1 2002, In : Current medicinal chemistry. 9, 1, p. 31-39 9 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)

Morphine tolerance in spinal cord is due to interaction between μ- and δ-receptors

Riba, P., Ben, Y., Smith, A. P., Furst, S. & Lee, N. M., Jan 12 2002, In : Journal of Pharmacology and Experimental Therapeutics. 300, 1, p. 265-272 8 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)
2001

Morphine tolerance in mice is independent of polymorphisms in opioid receptor sequences

Gant, T. M., Riba, P. & Lee, N. M., May 1 2001, In : Brain Research Bulletin. 55, 1, p. 59-63 5 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Reactions of morphine derivatives with phenyliodo(III)diacetate (PIDA): Synthesis of new morphine analogues+,++

Garadnay, S., Herczegh, P., Makleit, S., Friedmann, T., Riba, P. & Fürst, S., Jan 1 2001, In : Current medicinal chemistry. 8, 6, p. 621-626 6 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
1997

In vitro and in vivo pharmacology of novel naltrindole-related compounds

Ronai, A. Z., Gyires, K., Schmidhammer, H., Hosztafi, S., Borsodi, A., Spetea, M., Friedmann, T., Riba, P. & Furst, Z., Jan 1 1997, In : Medical Science Monitor. 3, 1, p. 1-5 5 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
1996
3 Citations (Scopus)

Glucose formation from methylglyoxal in hepatocytes from streptozotocin-induced diabetic mice: The effect of insulin

Kalapos, M. P., Riba, P., Garzó, T. & Mandl, J., Jan 1 1996, In : Experientia. 52, 8, p. 827-830 4 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
1994

Methylglyoxal and cell viability

Braun, L., Garzó, T., Riba, P., Mandl, J. & Kalapos, M. P., Aug 1994, In : International Journal of Biochemistry. 26, 8, p. 987-990 4 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

The role of the different types of opioid receptors in the effects of N-cyclopropylmethyl homologues of morphine

Friedmann, T., Riba, P., Tóth, Z., Hosztafi, S. & Fürst, S., Sep 1994, In : European Neuropsychopharmacology. 4, 3, 1 p.

Research output: Contribution to journalArticle

1992
3 Citations (Scopus)

The effect of A23187 on glucose production from methylglyoxal and pyruvate in isolated murine hepatocytes

Kalapos, M. P., Riba, P., Garzó, T. Á., Antoni, F. & Mandl, J., Mar 1992, In : International Journal of Biochemistry. 24, 3, p. 411-414 4 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)