• 1382 Citations
  • 21 h-Index
1987 …2019

Research output per year

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Research Output

  • 1382 Citations
  • 21 h-Index
  • 87 Article
  • 4 Review article
  • 1 Comment/debate
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Article
2019
Open Access
1 Citation (Scopus)

Different reactivity to glutathione but similar tumor cell toxicity of chalcones and their quinolinone analogues

d’Oliveira, G. D. C., Custodio, J. M. F., Moura, A. F., Napolitano, H. B., Pérez, C. N., Moraes, M. O., Prókai, L. & Perjési, P., Sep 1 2019, In : Medicinal Chemistry Research. 28, 9, p. 1448-1460 13 p.

Research output: Contribution to journalArticle

Open Access

Investigation of intestinal elimination and biliary excretion of ibuprofen in hyperglycemic rats

Kovács, N. P., Almási, A., Garai, K., Kuzma, M., Vancea, S., Fischer, E. & Perjési, P., Nov 1 2019, In : Canadian journal of physiology and pharmacology. 97, 11, p. 1080-1089 10 p.

Research output: Contribution to journalArticle

Toxicokinetic study of a gastroprotective dose of capsaicin by HPLC-FLD method

Kuzma, M., Fodor, K., Almási, A., Mózsik, G., Past, T. & Perjési, P., Aug 5 2019, In : Molecules. 24, 15, 2848.

Research output: Contribution to journalArticle

Open Access
2018

Changes in hepatic metabolic enzyme activities and biliary excretion of 4-nitrophenol in streptozotocin induced diabetic rats

Almási, A., Pinto, É. D. I. L. N., Kovács, N. P., Fischer, T., Markovics, Z., Fischer, E. & Perjési, P., Jan 1 2018, In : Brazilian Journal of Pharmaceutical Sciences. 54, 1, e17347.

Research output: Contribution to journalArticle

1 Citation (Scopus)

HPLC study on Fenton-reaction initiated oxidation of salicylic acid. Biological relevance of the reaction in intestinal biotransformation of salicylic acid

Nyúl, E., Kuzma, M., Mayer, M., Lakatos, S., Almási, A. & Perjési, P., Jan 1 2018, (Accepted/In press) In : Free Radical Research.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Oxidation of hydroxy- and dihydroxybenzoic acids under the udenfriend's conditions. An HPLC study

Kuzma, M., Kovács, N., Sziva, L., Maász, G., Avar, P. & Perjési, P., Jan 31 2018, In : Open Medicinal Chemistry Journal. 12, p. 13-22 10 p.

Research output: Contribution to journalArticle

Reagent-induced asymmetric induction in addition reaction of reduced glutathione onto bis-Mannich chalcones

Bernardes, A., D'Oliveira, G. D. C., Silezin, A., Kuzma, M., Molnár, S., Noda Pérez, C. & Perjési, P., Jul 1 2018, In : Archiv der Pharmazie. 351, 7, 1700386.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Selected ferrocenyl chalcones as DNA/BSA-interacting agents and inhibitors of DNA topoisomerase I and II activity

Konkoľová, E., Janočková, J., Perjési, P., Vašková, J. & Kožurková, M., Apr 15 2018, In : Journal of Organometallic Chemistry. 861, p. 1-9 9 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2017
2 Citations (Scopus)

Study of reactions of two Mannich bases derived of 4′-hydroxychalcones with glutathione by RP-TLC, RP-HPLC and RP-HPLC-ESI-MS analysis

Bernardes, A., Pérez, C. N., Mayer, M., Da Silva, C. C., Martins, F. T. & Perjési, P., Jun 1 2017, In : Journal of the Brazilian Chemical Society. 28, 6, p. 1048-1062 15 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2016

Chalcone derivatives cause accumulation of colon cancer cells in the G2/M phase and induce apoptosis

Kello, M., Drutovic, D., Pilatova, M. B., Tischlerova, V., Perjési, P. & Mojzis, J., Apr 1 2016, In : Life Sciences. 150, p. 32-38 7 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

HPLC analysis of in vivo intestinal absorption and oxidative metabolism of salicylic acid in the rat

Kuzma, M., Nyúl, E., Mayer, M., Fischer, E. & Perjési, P., Dec 1 2016, In : Biomedical Chromatography. 30, 12, p. 2044-2052 9 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Naturally occurring chalcones and their biological activities

Rozmer, Z. & Perjési, P., Feb 1 2016, In : Phytochemistry Reviews. 15, 1, p. 87-120 34 p.

Research output: Contribution to journalArticle

59 Citations (Scopus)
2015
10 Citations (Scopus)

3-Benzylidene-4-chromanones: A novel cluster of anti-tubercular agents

Das, U., Lorand, T., Dimmock, S. G., Perjesi, P. & Dimmock, J. R., Apr 1 2015, In : Journal of enzyme inhibition and medicinal chemistry. 30, 2, p. 259-263 5 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

A validated HPLC-FLD method for analysis of intestinal absorption and metabolism of capsaicin and dihydrocapsaicin in the rat

Kuzma, M., Fodor, K., Maász, G., Avar, P., Mózsik, G., Past, T., Fischer, E. & Perjési, P., Jan 5 2015, In : Journal of Pharmaceutical and Biomedical Analysis. 103, p. 59-66 8 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Determination of excited singlet-state dipole moments of methoxy and dimethylamino substituted benzylidenebenzosuberones using solvatochromic method

Tomečková, V., Veliká, B., Malhotra, S., Revická, M. & Perjési, P., 2015, In : Spectroscopy Letters. 48, 5, p. 317-323 7 p.

Research output: Contribution to journalArticle

Development and validation of an HPLC-DAD analysis for pharmacopoeial qualification of industrial Capsicum extracts

Kuzma, M., Fodor, K., Boros, B. & Perjési, P., Jan 1 2015, In : Journal of chromatographic science. 53, 1, p. 16-23 8 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Effect of experimental diabetes and insulin replacement on intestinal metabolism and excretion of 4-nitrophenol in rats

Fischer, E., Almási, A., Bojcsev, S., Fischer, T., Kovács, N. P. & Perjési, P., Feb 26 2015, In : Canadian journal of physiology and pharmacology. 93, 6, p. 459-464 6 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Some ferrocenyl chalcones as useful candidates for cancer treatment

Janka, V., Žatko, D., Ladislav, V., Pál, P., Janka, P. & Gabriela, M., Oct 1 2015, In : In Vitro Cellular and Developmental Biology - Animal. 51, 9, p. 964-974 11 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Synthesis and antiproliferative activity of cyclic arylidene ketones: a direct comparison of monobenzylidene and dibenzylidene derivatives

Huber, I., Zupkó, I., Kovács, I. J., Minorics, R., Gulyás-Fekete, G., Maász, G. & Perjési, P., Jun 28 2015, In : Monatshefte fur Chemie. 146, 6, p. 973-981 9 p., 1426.

Research output: Contribution to journalArticle

12 Citations (Scopus)
2014

Different effects of two cyclic chalcone analogues on redox status of Jurkat T cells

Rozmer, Z., Berki, T., Maász, G. & Perjési, P., Dec 2014, In : Toxicology in Vitro. 28, 8, p. 1359-1365 7 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
5 Citations (Scopus)

Spectroscopic Study on the Interaction of 4-dimethylaminochalcones with Phospholipids

Tomečková, V., Revická, M., Sassen, A., Veliká, B., Stupák, M. & Perjési, P., Jan 1 2014, In : Journal of Applied Spectroscopy. 81, 5, p. 812-819 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2013
1 Citation (Scopus)

Cyclic chalcone analogue KRP6 as a potent modulator of cell proliferation: An in vitro study in HUVECs

Ivanova, L., Varinska, L., Pilatova, M., Gal, P., Solar, P., Perjesi, P., Smetana, K., Ostro, A. & Mojzis, J., Jul 2013, In : Molecular Biology Reports. 40, 7, p. 4571-4580 10 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Effect of selected dimethylaminochalcones on some mitochondrial activities

Vašková, J., Reisch, R., Vaško, L., Poškrobová, M., Kron, I., Guzy, J. & Perjési, P., May 1 2013, In : In Vitro Cellular and Developmental Biology - Animal. 49, 5, p. 354-359 6 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Investigation of drug metabolism in various segments of small intestine in the rat

Bojcsev, S., Almási, A., Simon, H., Perjési, P. & Fischer, E., Mar 1 2013, In : Acta physiologica Hungarica. 100, 1, p. 115-123 9 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Metabolic enzyme activities and drug excretion in the small intestine and in the liver in the rat

Almási, A., Bojcsev, S., Fischer, T., Simon, H., Perjési, P. & Fischer, E., Dec 1 2013, In : Acta physiologica Hungarica. 100, 4, p. 478-488 11 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2012

(E)-2-Benzylidenebenzocyclanones: Part VII. Investigation of the conjugation reaction of two cytotoxic cyclic chalcone analogues with glutathione: An HPLC-MS study

Perjési, P., Maász, G., Reisch, R. & Benko, A., Aug 1 2012, In : Monatshefte fur Chemie. 143, 8, p. 1107-1114 8 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

(E)-2-Benzylidenebenzocyclanones, part VIII: Spectrophotometric determination of pK a values of some natural and synthetic chalcones and their cyclic analogues

Kron, I., Pudychová-Chovanová, Z., Veliká, B., Guzy, J. & Perjési, P., Jan 1 2012, In : Monatshefte fur Chemie. 143, 1, p. 13-17 5 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Anti-angiogenic activity of the flavonoid precursor 4-hydroxychalcone

Varinska, L., Van Wijhe, M., Belleri, M., Mitola, S., Perjesi, P., Presta, M., Koolwijk, P., Ivanova, L. & Mojzis, J., Sep 15 2012, In : European Journal of Pharmacology. 691, 1-3, p. 125-133 9 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)
12 Citations (Scopus)

Structural studies of seven homoisoflavonoids, six thiohomoisoflavonoids, and four structurally related compounds

Valkonen, A., Laihia, K., Kolehmainen, E., Kauppinen, R. & Perjési, P., Feb 1 2012, In : Structural Chemistry. 23, 1, p. 209-217 9 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)
2011
12 Citations (Scopus)

Applicazione di biomarkers molecolari epidemiologici mediante il monitoraggiodegli effetti del trattamento nel cancro colorettale durante uno studio di follow

Translated title of the contribution: Application of molecular epidemiological biomarkers by monitoring the effects of treatment in colorectal cancer during follow-up studyEmber, Á., Budán, F., Nowrasteh, G., Varjas, T., Prantner, I., Gobel, G., Horvath, Ö. P., Illényi, L., Cseh, J., Perjési, P., Orsós, Z., Gergely, P., Fehér, K., Ember, I. & Kiss, I., Jun 1 2011, In : European Journal of Oncology. 16, 2, p. 99-104 6 p.

Research output: Contribution to journalArticle

HPLC quantification of 4-nitrophenol and its conjugated metabolites from bile

Almási, A., Fischer, E. & Perjési, P., Nov 29 2011, In : Scientia Pharmaceutica. 79, 4, p. 837-847 11 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
10 Citations (Scopus)
2010

Activation of oxidative stress response by hydroxyl substituted chalcones and cyclic chalcone analogues in mitochondria

Guzy, J., Vašková-Kubálková, J., Rozmer, Z., Fodor, K., Mareková, M., Poškrobová, M. & Perjési, P., Feb 5 2010, In : FEBS letters. 584, 3, p. 567-570 4 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

In vitro antiproliferative and antiangiogenic effects of synthetic chalcone analogues

Pilatova, M., Varinska, L., Perjesi, P., Sarissky, M., Mirossay, L., Solar, P., Ostro, A. & Mojzis, J., Aug 1 2010, In : Toxicology in Vitro. 24, 5, p. 1347-1355 9 p.

Research output: Contribution to journalArticle

54 Citations (Scopus)
2009

Assessment of the effect of cyclic chalcone analogues on mitochondrial membrane and DNA

Kubálková, J., Tomečková, V., Perjési, P. & Guzy, J., Mar 1 2009, In : Central European Journal of Biology. 4, 1, p. 90-96 7 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Early modification of c-myc, Ha-ras and p53 expressions by chemical carcinogens (DMBA, MNU)

Budán, F., Varjas, T., Nowrasteh, G., Prantner, I., Varga, Z., Ember, Á., Cseh, J., Gombos, K., Pázsit, E., Gobel, G., Bauer, M., Gracza, T., Arany, I., Perjési, P. Á. L., Ember, I. & Kiss, I., Jul 1 2009, In : In Vivo. 23, 4, p. 591-598 8 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Some fluorescence properties of dimethylaminochalcone and its novel cyclic analogues

Tomečkova, V., Poškrobova, M., Štefanišinova, M. & Perjési, P., Dec 2009, In : Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy. 74, 5, p. 1242-1246 5 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2008

Comparison of effects of some cyclic chalcone analogues on selected mitochondrial functions

Perjési, P., Kubálková, J., Chovanová, Z., Mareková, M., Rozmer, Z., Fodor, K., Chavková, Z., Tomečková, V. & Guzy, J., Dec 1 2008, In : Pharmazie. 63, 12, p. 899-903 5 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Design, synthesis and antiproliferative activity of some 3-benzylidene-2,3-dihydro-1-benzopyran-4-ones which display selective toxicity for malignant cells

Perjési, P., Das, U., De Clercq, E., Balzarini, J., Kawase, M., Sakagami, H., Stables, J. P., Lorand, T., Rozmer, Z. & Dimmock, J. R., Apr 1 2008, In : European Journal of Medicinal Chemistry. 43, 4, p. 839-845 7 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)

Early modification of c-myc, Ha-ras and p53 expressions by N-methyl-N-nitrosourea

Budán, F., Varjas, T., Nowrasteh, G., Varga, Z., Boncz, I., Cseh, J., Prantner, I., Antal, T., Pázsit, E., Góbel, G., Bauer, M., Gracza, T., Perjési, P., Ember, I. & Gyóngyi, Z., Nov 1 2008, In : In Vivo. 22, 6, p. 793-798 6 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Mechanistic investigations on the antioxidant action of a neuroprotective estrogen derivative

Prokai-Tatrai, K., Perjesi, P., Rivera-Portalatin, N. M., Simpkins, J. W. & Prokai, L., Mar 1 2008, In : Steroids. 73, 3, p. 280-288 9 p.

Research output: Contribution to journalArticle

56 Citations (Scopus)
2006
27 Citations (Scopus)

Comparison of the effects of selected chalcones, dihydrochalcones and some cyclic flavonoids on mitochondrial outer membrane determined by fluorescence spectroscopy

Tomečková, V., Guzy, J., Kušnír, J., Fodor, K., Mareková, M., Chavková, Z. & Perjési, P., Nov 30 2006, In : Journal of biochemical and biophysical methods. 69, 1-2, p. 143-150 8 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)