• 1547 Citations
  • 21 h-Index
19992019

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2019

Copper-free dual labeling of DNA by triazines and cyclopropenes as minimal orthogonal and bioorthogonal functions

Reisacher, U., Ploschik, D., Rönicke, F., Cserép, G. B., Kele, P. & Wagenknecht, H. A., Apr 14 2019, In : Chemical Science. 10, 14, p. 4032-4037 6 p.

Research output: Contribution to journalArticle

Open Access
7 Citations (Scopus)

Triazine-Modified 7-Deaza-2′-deoxyadenosines: Better Suited for Bioorthogonal Labeling of DNA by PCR than 2′-Deoxyuridines

Reisacher, U., Groitl, B., Strasser, R., Cserép, G. B., Kele, P. & Wagenknecht, H. A., Jun 19 2019, In : Bioconjugate Chemistry. 30, 6, p. 1773-1780 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2018

A rapid and concise setup for the fast screening of FRET pairs using bioorthogonalized fluorescent dyes

Petrovics, R., Söveges, B., Egyed, A., Knorr, G., Kormos, A., Imre, T., Török, G., Zeke, A., Kocsmár, É., Lotz, G., Kele, P. & Németh, K., Jan 1 2018, In : Organic and Biomolecular Chemistry. 16, 16, p. 2997-3005 9 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Bioorthogonally Applicable Fluorogenic Cyanine-Tetrazines for No-Wash Super-Resolution Imaging

Knorr, G., Kozma, E., Schaart, J. M., Németh, K., Török, G. & Kele, P., Apr 18 2018, In : Bioconjugate Chemistry. 29, 4, p. 1312-1318 7 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Bistetrazine-Cyanines as Double-Clicking Fluorogenic Two-Point Binder or Crosslinker Probes

Kormos, A., Koehler, C., Fodor, E. A., Rutkai, Z. R., Martin, M. E., Mező, G., Lemke, E. A. & Kele, P., Jan 1 2018, (Accepted/In press) In : Chemistry - A European Journal.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Synthesis of 7-Azido-3-Formylcoumarin - A Key Precursor in Bioorthogonally Applicable Fluorogenic Dye Synthesis

Pünkösti, Z., Kele, P. & Herner, A., Jan 1 2018, (Accepted/In press) In : Journal of Heterocyclic Chemistry.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Tracking down protein-protein interactions: Via a FRET-system using site-specific thiol-labeling

Söveges, B., Imre, T., Póti, A. L., Sok, P., Kele, Z., Alexa, A., Kele, P. & Németh, K., Jan 1 2018, In : Organic and Biomolecular Chemistry. 16, 32, p. 5756-5763 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2017

Bioorthogonal double-fluorogenic siliconrhodamine probes for intracellular super-resolution microscopy

Kozma, E., Estrada Girona, G., Paci, G., Lemke, E. A. & Kele, P., Jan 1 2017, In : Chemical Communications. 53, 50, p. 6696-6699 4 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Bisazide Cyanine Dyes as Fluorogenic Probes for Bis-Cyclooctynylated Peptide Tags and as Fluorogenic Cross-Linkers of Cyclooctynylated Proteins

Demeter, O., Kormos, A., Koehler, C., Mező, G., Németh, K., Kozma, E., Takács, L. B., Lemke, E. A. & Kele, P., May 17 2017, In : Bioconjugate Chemistry. 28, 5, p. 1552-1559 8 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
2016

A Double-Clicking Bis-Azide Fluorogenic Dye for Bioorthogonal Self-Labeling Peptide Tags

Demeter, O., Fodor, E. A., Kállay, M., Mez, G., Németh, K., Szabó, P. T. & Kele, P., Apr 25 2016, In : Chemistry - A European Journal. 22, 18, p. 6382-6388 7 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

A systematic study of protein labeling by fluorogenic probes using cysteine targeting vinyl sulfone-cyclooctyne tags

Söveges, B., Imre, T., Szende, T., Póti, L., Cserép, G. B., Hegedűs, T., Kele, P. & Németh, K., 2016, In : Organic and Biomolecular Chemistry. 14, 25, p. 6071-6078 8 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Cell-free synthesis of functional human epidermal growth factor receptor: Investigation of ligand-independent dimerization in Sf21 microsomal membranes using non-canonical amino acids

Quast, R. B., Ballion, B., Stech, M., Sonnabend, A., Varga, B. R., Wüstenhagen, D. A., Kele, P., Schiller, S. M. & Kubick, S., Sep 27 2016, In : Scientific Reports. 6, 34048.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Hydrophilic trans-Cyclooctenylated Noncanonical Amino Acids for Fast Intracellular Protein Labeling

Kozma, E., Nikić, I., Varga, B. R., Aramburu, I. V., Kang, J. H., Fackler, O. T., Lemke, E. A. & Kele, P., Aug 17 2016, In : ChemBioChem. p. 1518-1524 7 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Inside Cover: Hydrophilic trans-Cyclooctenylated Noncanonical Amino Acids for Fast Intracellular Protein Labeling (ChemBioChem 16/2016)

Kozma, E., Nikić, I., Varga, B. R., Aramburu, I. V., Kang, J. H., Fackler, O. T., Lemke, E. A. & Kele, P., Aug 17 2016, In : ChemBioChem. 17, 16, p. 1483 1 p.

Research output: Contribution to journalArticle

New Red-Emitting Tetrazine-Phenoxazine Fluorogenic Labels for Live-Cell Intracellular Bioorthogonal Labeling Schemes

Knorr, G., Kozma, E., Herner, A., Lemke, E. A. & Kele, P., 2016, (Accepted/In press) In : Chemistry - A European Journal.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Polarity Sensitive Bioorthogonally Applicable Far-Red Emitting Labels for Postsynthetic Nucleic Acid Labeling by Copper-Catalyzed and Copper-Free Cycloaddition

Eördögh, Á., Steinmeyer, J., Peewasan, K., Schepers, U., Wagenknecht, H. A. & Kele, P., Feb 17 2016, In : Bioconjugate Chemistry. 27, 2, p. 457-464 8 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Scope and Limitations of Typical Copper-Free Bioorthogonal Reactions with DNA: Reactive 2′-Deoxyuridine Triphosphates for Postsynthetic Labeling

Merkel, M., Arndt, S., Ploschik, D., Cserép, G. B., Wenge, U., Kele, P. & Wagenknecht, H. A., Sep 2 2016, In : Journal of Organic Chemistry. 81, 17, p. 7527-7538 12 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)
2015

Designer amphiphilic proteins as building blocks for the intracellular formation of organelle-like compartments

Huber, M. C., Schreiber, A., Von Olshausen, P., Varga, B. R., Kretz, O., Joch, B., Barnert, S., Schubert, R., Eimer, S., Kele, P. & Schiller, S. M., Jan 1 2015, In : Nature Materials. 14, 1, p. 125-132 8 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)

Synthesis and Evaluation of Nicotinic Acid Derived Tetrazines for Bioorthogonal Labeling

Cserép, G. B., Demeter, O., Bätzner, E., Kállay, M., Wagenknecht, H. A. & Kele, P., Sep 16 2015, In : Synthesis (Germany). 47, 18, p. 2738-2744 7 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)
2014

2′-Deoxyuridine conjugated with a reactive monobenzocyclooctyne as a DNA building block for copper-free click-type postsynthetic modification of DNA

Stubinitzky, C., Cserép, G. B., Bätzner, E., Kele, P. & Wagenknecht, H. A., Jan 1 2014, In : Chemical Communications. 50, 76, p. 11218-11221 4 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Fluorogenic tagging of peptides via Cys residues using thiol-specific vinyl sulfone affinity tags

Cserép, G. B., Baranyai, Z., Komáromy, D., Horváti, K., Bosze, S. & Kele, P., Sep 2 2014, In : Tetrahedron. 70, 35, p. 5961-5965 5 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

New generation of bioorthogonally applicable fluorogenic dyes with visible excitations and large stokes shifts

Herner, A., Estrada Girona, G., Nikić, I., Kállay, M., Lemke, E. A. & Kele, P., Jul 16 2014, In : Bioconjugate Chemistry. 25, 7, p. 1370-1374 5 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)
2013

A new family of bioorthogonally applicable fluorogenic labels

Herner, A., Nikić, I., Kállay, M., Lemke, E. A. & Kele, P., May 28 2013, In : Organic and Biomolecular Chemistry. 11, 20, p. 3297-3306 10 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

New luminescent ruthenium probes for detection of diacetyl

Kele, P., Li, X. & Duerkop, A., May 1 2013, In : Microchemical Journal. 108, p. 156-160 5 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

NIR mega-stokes fluorophores for bioorthogonal labeling and energy transfer systems - An efficient quencher for daunomycin

Cserép, G. B., Enyedi, K. N., Demeter, A., Mezo, G. & Kele, P., Feb 1 2013, In : Chemistry - An Asian Journal. 8, 2, p. 494-502 9 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Tyrosine specific sequential labeling of proteins

Cserép, G. B., Herner, A., Wolfbeis, O. S. & Kele, P., Nov 1 2013, In : Bioorganic and Medicinal Chemistry Letters. 23, 21, p. 5776-5778 3 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)
2012

A non-fluorinated monobenzocyclooctyne for rapid copper-free click reactions

Varga, B. R., Kállay, M., Hegyi, K., Béni, S. & Kele, P., Jan 16 2012, In : Chemistry - A European Journal. 18, 3, p. 822-828 7 p.

Research output: Contribution to journalArticle

51 Citations (Scopus)
2011

Brightly fluorescent purple and blue labels for amines and proteins

Link, M., Kele, P., Achatz, D. E. & Wolfbeis, O. S., Sep 15 2011, In : Bioorganic and Medicinal Chemistry Letters. 21, 18, p. 5538-5542 5 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2010

Clickable long-wave "mega-stokes" fluorophores for orthogonal chemoselective labeling of cells

Nagy, K., Orbán, E., Bosze, S. & Kele, P., Apr 1 2010, In : Chemistry - An Asian Journal. 5, 4, p. 773-777 5 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Determination of propylenethiourea, the main metabolite of propineb, in tomato by HILIC-MS

Tölgyesi, L., Kele, P. & Torkos, K., Jun 1 2010, In : Chromatographia. 71, SUPPL. 1, p. S75-S80

Research output: Contribution to journalArticle

10 Citations (Scopus)

New far-red and near-infrared fluorescent probes with large stokes shifts for dual covalent labeling of DNA

Ehrenschwender, T., Varga, B. R., Kele, P. & Wagenknecht, H. A., Aug 2 2010, In : Chemistry - An Asian Journal. 5, 8, p. 1761-1764 4 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)
2009

Clickable fluorophores for biological Labeling - With or without copper

Kele, P., Li, X., Link, M., Nagy, K., Herner, A., Lrincz, K., Béni, S. & Wolfbeis, O. S., Sep 25 2009, In : Organic and Biomolecular Chemistry. 7, 17, p. 3486-3490 5 p.

Research output: Contribution to journalArticle

56 Citations (Scopus)

Comparison of a nucleosidic vs non-nucleosidic postsynthetic "click" modification of DNA with base-labile fluorescent probes

Berndl, S., Herzig, N., Kele, P., Lachmann, D., Li, X., Wolfbeis, O. S. & Wagenknecht, H. A., Mar 2009, In : Bioconjugate Chemistry. 20, 3, p. 558-564 7 p.

Research output: Contribution to journalArticle

83 Citations (Scopus)

Dual labeling of biomolecules by using click chemistry: A sequential approach

Kele, P., Mezö, G., Achatz, D. & Wolfbeis, O. S., Jan 2 2009, In : Angewandte Chemie - International Edition. 48, 2, p. 344-347 4 p.

Research output: Contribution to journalArticle

99 Citations (Scopus)

Probing the activity of matrix metalloproteinase II with a sequentially click-labeled silica nanoparticle FRET probe

Achatz, D. E., Mezo, G., Kele, P. & Wolfbeis, O. S., Sep 21 2009, In : ChemBioChem. 10, 14, p. 2316-2320 5 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)

The sequential Sonogashira-click reaction: A versatile route to 4-aryl-1,2,3-triazoles

Lörincz, K., Kele, P. & Novák, Z., Dec 21 2009, In : Synthesis. 20, p. 3527-3532 6 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)
2008

Fluorescent silica nanoparticles

Mader, H., Li, X., Saleh, S., Link, M., Kele, P. & Wolfbeis, O. S., May 2008, In : Annals of the New York Academy of Sciences. 1130, p. 218-223 6 p.

Research output: Contribution to journalArticle

45 Citations (Scopus)

Substituent dependent fluorescence response of diazacrown-based PET sensors

Nagy, K., Béni, S., Szakács, Z., Bényei, A. C., Noszál, B., Kele, P. & Kotschy, A., Jun 30 2008, In : Tetrahedron. 64, 27, p. 6191-6195 5 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2006

Spectroscopic detection of Saxitoxin: An alternative to mouse bioassay

Kele, P., Orbulescu, J., Gawley, R. E. & Leblanc, R. M., Apr 6 2006, In : Chemical Communications. 14, p. 1494-1496 3 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

The development of conformational-dynamics-based sensors

Kele, P., Nagy, K. & Kotschy, A., Apr 10 2006, In : Angewandte Chemie - International Edition. 45, 16, p. 2565-2567 3 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2005

Synthesis and spectroscopy of coumarin derivatives for saxitoxin detection!

Orbulescu, J., Kele, P., Kotschy, A. & Leblanc, R. M., Aug 14 2005, In : Journal of Materials Chemistry. 15, 30, p. 3084-3088 5 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2003

Analysis of matrix metalloproteinase triple-helical peptidase activity with substrates incorporating fluorogenic L- or D-amino acids

Lauer-Fields, J. L., Kele, P., Sui, G., Nagase, H., Leblanc, R. M. & Fields, G. B., Oct 1 2003, In : Analytical Biochemistry. 321, 1, p. 105-115 11 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)
2002

Coumaryl crown ether based chemosensors: Selective detection of saxitoxin in the presence of sodium and potassium ions

Kele, P., Orbulescu, J., Calhoun, T. L., Gawley, R. E. & Leblanc, R. M., Jun 17 2002, In : Tetrahedron Letters. 43, 25, p. 4413-4416 4 p.

Research output: Contribution to journalArticle

51 Citations (Scopus)

Langmuir monolayer and Langmuir-Blodgett film studies of an amphiphilic coumaryl crown ether

Kele, P., Orbulescu, J., Calhoun, T. L., Gawley, R. E. & Leblanc, R. M., Oct 29 2002, In : Langmuir. 18, 22, p. 8523-8526 4 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)
2001

A new fluorescent chemosensor for copper ions based on tripeptide glycyl-histidyl-lysine (GHK)

Zheng, Y., Huo, Q., Kele, P., Andreopoulos, F. M., Pham, S. M. & Leblanc, R. M., Oct 18 2001, In : Organic Letters. 3, 21, p. 3277-3280 4 p.

Research output: Contribution to journalArticle

129 Citations (Scopus)

Langmuir and Langmuir-Blodgett film characterization of a new amphiphilic coumarin derivative

Kele, P., Orbulescu, J., Mello, S. V., Mabrouki, M. & Leblanc, R. M., Nov 13 2001, In : Langmuir. 17, 23, p. 7286-7290 5 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Metal complexation with langmuir monolayers of histidyl peptide lipids

Huo, Q., Sui, G., Zheng, Y., Kele, P., Leblanc, R. M., Hasegawa, T., Nishijo, J. & Umemura, J., Nov 19 2001, In : Chemistry - A European Journal. 7, 22, p. 4796-4804 9 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Reexamination of the monolayer properties of a fluorescein amphiphile in Langmuir and Langmuir-Schaefer films

Orbulescu, J., Mello, S. V., Huo, Q., Sui, G., Kele, P. & Leblanc, R. M., Mar 6 2001, In : Langmuir. 17, 5, p. 1525-1528 4 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Synthesis of a coumarin based fluorescent amino acid

Sui, G., Kele, P., Orbulescu, J., Huo, Q. & Leblanc, R. M., Jan 2001, In : Letters in Peptide Science. 8, 1, p. 47-51 5 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)
2000

Combinatorial surface chemistry - Is it possible?

Huo, Q., Sui, G., Kele, P. & Leblanc, R. M., May 15 2000, In : Angewandte Chemie - International Edition. 39, 10, p. 1854-1857 4 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)