• 2957 Citations
  • 30 h-Index
1964 …2014

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

2014

A flexible, interactive software tool for fitting the parameters of neuronal models

Friedrich, P., Vella, M., Gulyás, A. I., Freund, T. F. & Káli, S., Jul 10 2014, In : Frontiers in Neuroinformatics. 8, JULY, 63.

Research output: Contribution to journalArticle

13 Citations (Scopus)
2012

CalpB modulates border cell migration in Drosophila egg chambers

Kákai, E., Páldy, F. S., Somogyi, K., Chougule, A., Pál, M., Kerekes, É., Deák, P., Friedrich, P., Dombrádi, V. & Ádám, G., Sep 19 2012, In : BMC developmental biology. 12, 20.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)
2011

Calpain-catalyzed proteolysis of human dutpase specifically removes the nuclear localization signal peptide

Bozóky, Z., Róna, G., Klement, É., Medzihradszky, K. F., Merényi, G., Vértessy, B. G. & Friedrich, P., May 26 2011, In : PloS one. 6, 5, e19546.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2010

Conservation of male-specific expression of novel phosphoprotein phosphatases in Drosophila

Ádám, C., Henn, L., Miskei, M., Erdélyi, M., Friedrich, P. & Dombrádi, V., Sep 1 2010, In : Development Genes and Evolution. 220, 3-4, p. 123-128 6 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2009

Cold stability of intrinsically disordered proteins

Tantos, A., Friedrich, P. & Tompa, P., Jan 22 2009, In : FEBS letters. 583, 2, p. 465-469 5 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)

Folding transitions in calpain activator peptides studied by solution NMR spectroscopy

Toke, O., Bánóczi, Z., Tárkányi, G., Friedrich, P. & Hudecz, F., Jul 13 2009, In : Journal of Peptide Science. 15, 6, p. 404-410 7 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Identifying calpain substrates in intact S2 cells of Drosophila

Bozoky, Z., Alexa, A., Dancsok, J., Gogl, G., Klement, E., Medzihradszky, K. F. & Friedrich, P., Jan 15 2009, In : Archives of Biochemistry and Biophysics. 481, 2, p. 219-225 7 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Regulation of calpain B from Drosophila melanogaster by phosphorylation

Kovács, L., Alexa, A., Klement, E., Kókai, E., Tantos, Á., Gógl, G., Sperka, T., Medzihradszky, K. F., Tözsér, J., Dombrádi, V. & Friedrich, P., Sep 1 2009, In : FEBS Journal. 276, 17, p. 4959-4972 14 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2008

Calcium-induced tripartite binding of intrinsically disordered calpastatin to its cognate enzyme, calpain

Kiss, R., Bozoky, Z., Kovács, D., Róna, G., Friedrich, P., Dvortsák, P., Weisemann, R., Tompa, P. & Perczel, A., Jun 25 2008, In : FEBS letters. 582, 15, p. 2149-2154 6 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)

Corrigendum to "Calcium-induced tripartite binding of intrinsically disordered calpastatin to its cognate enzyme, calpain" [FEBS Lett. 582 (2008) 2149-2154] (DOI:10.1016/j.febslet.2008.05.032)

Kiss, R., Bozoky, Z., Kovács, D., Róna, G., Friedrich, P., Dvortsák, P., Weisemann, R., Tompa, P. & Perczel, A., Aug 6 2008, In : FEBS letters. 582, 18, 1 p.

Research output: Contribution to journalComment/debate

Novel cell-penetrating calpain substrate

Bánóczi, Z., Alexa, A., Farkas, A., Friedrich, P. & Hudecz, F., Jul 1 2008, In : Bioconjugate Chemistry. 19, 7, p. 1375-1381 7 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Synthetic calpain activator boosts neuronal excitability without extra Ca2+

Világi, I., Kiss, D. S., Farkas, A., Borbély, S., Tárnok, K., Halasy, K., Bánóczi, Z., Hudecz, F. & Friedrich, P., Aug 4 2008, In : Molecular and Cellular Neuroscience. 38, 4, p. 629-636 8 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2007

Synthesis of cell-penetrating conjugates of calpain activator peptides

Bánoczi, Z., Tantos, Á., Farkas, A., Tompa, P., Friedrich, P. & Hudecz, F., Jan 1 2007, In : Bioconjugate Chemistry. 18, 1, p. 130-137 8 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
2006

A novel two-dimensional electrophoresis technique for the identification of intrinsically unstructured proteins

Csizmók, V., Szollosi, E., Friedrich, P. & Tompa, P., Feb 1 2006, In : Molecular and Cellular Proteomics. 5, 2, p. 265-273 9 p.

Research output: Contribution to journalArticle

54 Citations (Scopus)

CG15031/PPYR1 is an intrinsically unstructured protein that interacts with protein phosphatase Y

Kókai, E., Tantos, Á., Vissi, E., Szöor, B., Tompa, P., Gausz, J., Alphey, L., Friedrich, P. & Dombrádi, V., Jul 1 2006, In : Archives of Biochemistry and Biophysics. 451, 1, p. 59-67 9 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2005

Digestive versus regulatory proteases: On calpain action in vivo

Friedrich, P. & Bozóky, Z., Oct 24 2005, In : Biological Chemistry. 386, 7, p. 609-612 4 p.

Research output: Contribution to journalShort survey

32 Citations (Scopus)

Enhancement of synaptic strength in the somatosensory cortex following nerve injury does not parallel behavioural alterations

Világi, I., Bárdos, G., Dénes, K., Farkas, B. & Friedrich, P., Jan 30 2005, In : Brain Research Bulletin. 64, 6, p. 463-469 7 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

FEBS Letters Budapest issue

Friedrich, P., Jun 13 2005, In : FEBS letters. 579, 15, 1 p.

Research output: Contribution to journalEditorial

Multiple interactions of the 'transducer' govern its function in calpain activation by Ca2+

Bozóky, Z., Alexa, A., Tompa, P. & Friedrich, P., Jun 15 2005, In : Biochemical Journal. 388, 3, p. 741-744 4 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

NMR relaxation studies on the hydrate layer of intrinsically unstructured proteins

Bokor, M., Csizmók, V., Kovács, D., Bánki, P., Friedrich, P., Tompa, P. & Tompa, K., Mar 2005, In : Biophysical journal. 88, 3, p. 2030-2037 8 p.

Research output: Contribution to journalArticle

63 Citations (Scopus)

Primary contact sites in intrinsically unstructured proteins: The case of calpastatin and microtubule-associated protein 2

Csizmók, V., Bokor, M., Bánki, P., Klement, É., Medzihradszky, K. F., Friedrich, P., Tompa, K. & Tompa, P., Mar 15 2005, In : Biochemistry. 44, 10, p. 3955-3964 10 p.

Research output: Contribution to journalArticle

83 Citations (Scopus)
2004

Autolytic activation and localization in Schneider cells (S2) of calpain B from Drosophila

Farkas, A., Tompa, P., Schád, É., Sinka, R., Jékely, G. & Friedrich, P., Mar 1 2004, In : Biochemical Journal. 378, 2, p. 299-305 7 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Calpain as a multi-site regulator of cell cycle

Jánossy, J., Ubezio, P., Apáti, Á., Magócsi, M., Tompa, P. & Friedrich, P., Apr 15 2004, In : Biochemical Pharmacology. 67, 8, p. 1513-1521 9 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)

Contribution of Distinct Structural Elements to Activation of Calpain by Ca2+ Ions

Alexa, A., Bozóky, Z., Farkas, A., Tompa, P. & Friedrich, P., May 7 2004, In : Journal of Biological Chemistry. 279, 19, p. 20118-20126 9 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Differential distribution of calpain small subunit 1 and 2 in rat brain

Friedrich, P., Papp, H., Halasy, K., Farkas, A., Farkas, B., Tompa, P. & Kása, P., Apr 2004, In : European Journal of Neuroscience. 19, 7, p. 1819-1825 7 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

DUK114, tin Drosophila orthologue of bovine brain calpain activator protein, is a molecular chaperone

Farkas, A., Nardai, G., Csermely, P., Tompa, P. & Friedrich, P., Oct 1 2004, In : Biochemical Journal. 383, 1, p. 165-170 6 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Ischemia-induced increase in long-term potentiation is warded off by specific calpain inhibitor PD150606

Farkas, B., Tantos, A., Schlett, K., Világi, I. & Friedrich, P., Oct 22 2004, In : Brain research. 1024, 1-2, p. 150-158 9 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

On the sequential determinants of calpain cleavage

Tompa, P., Buzder-Lantos, P., Tantos, A., Farkas, A., Szilágyi, A., Bánóczi, Z., Hudecz, F. & Friedrich, P., May 14 2004, In : Journal of Biological Chemistry. 279, 20, p. 20775-20785 11 p.

Research output: Contribution to journalArticle

243 Citations (Scopus)

Preformed structural elements feature in partner recognition by intrinsically unstructured proteins

Fuxreiter, M., Simon, I., Friedrich, P. & Tompa, P., May 14 2004, In : Journal of molecular biology. 338, 5, p. 1015-1026 12 p.

Research output: Contribution to journalArticle

397 Citations (Scopus)

The calpain-system of Drosophila melanogaster: Coming of age

Friedrich, P., Tompa, P. & Farkas, A., Oct 1 2004, In : BioEssays. 26, 10, p. 1088-1096 9 p.

Research output: Contribution to journalReview article

29 Citations (Scopus)

The intriguing Ca 2+ requirement of calpain activation

Friedrich, P., Oct 29 2004, In : Biochemical and Biophysical Research Communications. 323, 4, p. 1131-1133 3 p.

Research output: Contribution to journalShort survey

47 Citations (Scopus)
2003

Binding-induced folding transitions in calpastatin subdomains A and C

Mucsi, Z., Hudecz, F., Hollósi, M., Tompa, P. & Friedrich, P., Oct 1 2003, In : Protein Science. 12, 10, p. 2327-2336 10 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)

Molecular cloning and RNA expression of a novel Drosophila calpain, Calpain C

Spadoni, C., Farkas, A., Sinka, R., Tompa, P. & Friedrich, P., Mar 28 2003, In : Biochemical and biophysical research communications. 303, 1, p. 343-349 7 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Revisiting ubiquity and tissue specificity of human calpains

Farkas, A., Tompa, P. & Friedrich, P., Jun 1 2003, In : Biological Chemistry. 384, 6, p. 945-949 5 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)
2002

A novel human small subunit of calpains

Schád, É., Farkas, A., J́ekely, G., Tompa, P. & Friedrich, P., Mar 1 2002, In : Biochemical Journal. 362, 2, p. 383-388 6 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Calpastatin subdomains A and C are activators of calpain

Tompa, P., Mucsi, Z., Orosz, G. & Friedrich, P., Mar 15 2002, In : Journal of Biological Chemistry. 277, 11, p. 9022-9026 5 p.

Research output: Contribution to journalArticle

45 Citations (Scopus)

The phosphorylation state of threonine-220, a uniquely phosphatase-sensitive protein kinase a site in microtubule-associated protein MAP2c, regulates microtubule binding and stability

Alexa, A., Schmidt, G., Tompa, P., Ogueta, S., Vázquez, J., Kulcsár, P., Kovács, J., Dombrádi, V. & Friedrich, P., Oct 15 2002, In : Biochemistry. 41, 41, p. 12427-12435 9 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

The role of dimerization in prion replication

Tompa, P., Tusnády, G. E., Friedrich, P. & Simon, I., Jan 1 2002, In : Biophysical journal. 82, 4, p. 1711-1718 8 p.

Research output: Contribution to journalArticle

Open Access
43 Citations (Scopus)
2001

Domain III of calpain is a Ca2+-regulated phospholipid-binding domain

Tompa, P., Emori, Y., Sorimachi, H., Suzuki, K. & Friedrich, P., Jan 1 2001, In : Biochemical and biophysical research communications. 280, 5, p. 1333-1339 7 p.

Research output: Contribution to journalArticle

128 Citations (Scopus)

Frequency decoding of fast calcium oscillations by calpain

Tompa, P., Töth-Boconádi, R. & Friedrich, P., Jan 1 2001, In : Cell Calcium. 29, 3, p. 161-170 10 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)
2000
3 Citations (Scopus)
1 Citation (Scopus)

Inhibitory effect of a brain derived peptide preparation on the Ca++-dependent protease, calpain

Wronski, R., Tompa, P., Hutter-Paier, B., Crailsheim, K., Friedrich, P. & Windisch, M., Feb 24 2000, In : Journal of neural transmission. 107, 2, p. 145-157 13 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)

Kinetic analysis of human mu-calpain autolysis.

Tompa, P. & Friedrich, P., 2000, In : Methods in molecular biology (Clifton, N.J.). 144, p. 129-136 8 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
1999

Characterization of two recombinant Drosophila calpains. Calpa and a novel homolog, CALPB

Jékely, G. & Friedrich, P., Aug 20 1999, In : Journal of Biological Chemistry. 274, 34, p. 23893-23900 8 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

The evolution of the calpain family as reflected in paralogous chromosome regions

Jékely, G. & Friedrich, P., Aug 9 1999, In : Journal of Molecular Evolution. 49, 2, p. 272-281 10 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)
1998

Prion proteins as memory molecules: An hypothesis

Tompa, P. & Friedrich, P., Jan 1 1998, In : Neuroscience. 86, 4, p. 1037-1043 7 p.

Research output: Contribution to journalComment/debate

38 Citations (Scopus)

Synaptic metaplasticity and the local charge effect in postsynaptic densities

Tompa, P. & Friedrich, P., Mar 1 1998, In : Trends in Neurosciences. 21, 3, p. 97-102 6 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

TER94, a Drosophila homolog of the membrane fusion protein CDC48/p97, is accumulated in nonproliferating cells: In the reproductive organs and in the brain of the imago

Pintér, M., Jékely, G., Szepesi, R. J., Farkas, A., Theopold, U., Meyer, H. E., Lindholm, D., Nässel, D. R., Hultmark, D. & Friedrich, P., Feb 1 1998, In : Insect Biochemistry and Molecular Biology. 28, 2, p. 91-98 8 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)
1996

Autolysis parallels activation of μ-calpain

Baki, A., Tompa, P., Alexa, A., Molnar, O. & Friedrich, P., Jan 1 1996, In : Biochemical Journal. 318, 3, p. 897-901 5 p.

Research output: Contribution to journalArticle

91 Citations (Scopus)