• 5409 Citations
  • 33 h-Index
19942019

Research output per year

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Research Output

Active site residue involvement in monoamine or diamine oxidation catalysed by pea seedling amine oxidase

Di Paolo, M. L., Lunelli, M., Fuxreiter, M., Rigo, A., Simon, I. & Scarpa, M., Apr 1 2011, In : FEBS Journal. 278, 8, p. 1232-1243 12 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

A Derived Allosteric Switch Underlies the Evolution of Conditional Cooperativity between HOXA11 and FOXO1

Nnamani, M. C., Ganguly, S., Erkenbrack, E. M., Lynch, V. J., Mizoue, L. S., Tong, Y., Darling, H. L., Fuxreiter, M., Meiler, J. & Wagner, G. P., Jun 7 2016, In : Cell Reports. 15, 10, p. 2097-2108 12 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Altered dynamics may drift pathological fibrillization in membraneless organelles

Tüű-Szabó, B., Hoffka, G., Duro, N. & Fuxreiter, M., Oct 2019, In : Biochimica et Biophysica Acta - Proteins and Proteomics. 1867, 10, p. 988-998 11 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Alternative splicing of intrinsically disordered regions and rewiring of protein interactions

Buljan, M., Chalancon, G., Dunker, A. K., Bateman, A., Balaji, S., Fuxreiter, M. & Babu, M. M., Jun 1 2013, In : Current Opinion in Structural Biology. 23, 3, p. 443-450 8 p.

Research output: Contribution to journalReview article

100 Citations (Scopus)

An EcoRI-RsrI chimeric restriction endonuclease retains parental sequence specificity

Chuluunbaatar, T., Ivanenko-Johnston, T., Fuxreiter, M., Meleshko, R., Raskó, T., Simon, I., Heitman, J. & Kiss, A., May 1 2007, In : Biochimica et Biophysica Acta - Proteins and Proteomics. 1774, 5, p. 583-594 12 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Checking nucleic acid crystal structures

Das, U., Chen, S., Fuxreiter, M., Vaguine, A. A., Richelle, J., Berman, H. M. & Wodak, S. J., Jul 4 2001, In : Acta Crystallographica Section D: Biological Crystallography. 57, 6, p. 813-828 16 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Classification of intrinsically disordered regions and proteins

Van Der Lee, R., Buljan, M., Lang, B., Weatheritt, R. J., Daughdrill, G. W., Dunker, A. K., Fuxreiter, M., Gough, J., Gsponer, J., Jones, D. T., Kim, P. M., Kriwacki, R. W., Oldfield, C. J., Pappu, R. V., Tompa, P., Uversky, V. N., Wright, P. E. & Babu, M. M., Jul 9 2014, In : Chemical reviews. 114, 13, p. 6589-6631 43 p.

Research output: Contribution to journalReview article

697 Citations (Scopus)

Close encounters of the third kind: Disordered domains and the interactions of proteins

Tompa, P., Fuxreiter, M., Oldfield, C. J., Simon, I., Dunker, A. K. & Uversky, V. N., Apr 27 2009, In : BioEssays. 31, 3, p. 328-335 8 p.

Research output: Contribution to journalArticle

181 Citations (Scopus)

Comparative redox and pK(a) calculations on cytochrome c3 from several Desulfovibrio species using continuum electrostatic methods

Martel, P. J., Soares, C. M., Baptista, A. M., Fuxreiter, M., Náray-Szabó, G., Louro, R. O. & Carrondo, M. A., Feb 1 1999, In : Journal of Biological Inorganic Chemistry. 4, 1, p. 73-86 14 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Computational analyses of the effect of novel amino acid clusters of human transglutaminase 2 on its structure and function

Thangaraju, K., Király, R., Mótyán, J. A., Ambrus, V. A., Fuxreiter, M. & Fésüs, L., Mar 1 2017, In : Amino Acids. 49, 3, p. 605-614 10 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
3 Citations (Scopus)

Computational approaches to restriction endonucleases

Fuxreiter, M., Osman, R. & Simon, I., Dec 29 2003, In : Journal of Molecular Structure: THEOCHEM. 666-667, p. 469-479 11 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Conformation and self-association of a hybrid peptide of cecropin A and melittin with improved antibiotic activity

Fernandez, I., Ubach, J., Fuxreiter, M., Andreu, J. M., Andreu, D. & Pons, M., Jan 1 1996, In : Angewandte Chemie - International Edition in English. 35, 13-14, p. 838-846 9 p.

Research output: Contribution to journalArticle

Conformation and self-association of a hybrid peptide of cecropin A and melittin with improved antibiotic activity

Fernández, I., Ubach, J., Fuxreiter, M., Andreu, J. M., Andreu, D. & Pons, M., 1996, In : Chemistry - A European Journal. 2, 7, p. 838-846 9 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Crystallization and preliminary X-ray analysis of porcine muscle prolyl oligopeptidase

Böcskei, Z., Fuxreiter, M., Náray-Szabó, G., Szabó, E. & Polgár, L., 1998, In : Acta Crystallographica Section D: Biological Crystallography. 54, 6 PART II, p. 1414-1415 2 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Disordered proteinaceous machines

Fuxreiter, M., Tóth-Petróczy, Á., Kraut, D. A., Matouschek, A. T., Lim, R. Y. H., Xue, B., Kurgan, L. & Uversky, V. N., Jul 9 2014, In : Chemical reviews. 114, 13, p. 6806-6843 38 p.

Research output: Contribution to journalReview article

63 Citations (Scopus)

Disordered tails of homeodomains facilitate DNA recognition by providing a trade-off between folding and specific binding

Tóth-Petróczy, Á., Simon, I., Fuxreiter, M. & Levy, Y., Oct 28 2009, In : Journal of the American Chemical Society. 131, 42, p. 15084-15085 2 p.

Research output: Contribution to journalArticle

53 Citations (Scopus)

Dynamic protein-DNA recognition: Beyond what can be seen

Fuxreiter, M., Simon, I. & Bondos, S., Aug 1 2011, In : Trends in Biochemical Sciences. 36, 8, p. 415-423 9 p.

Research output: Contribution to journalReview article

104 Citations (Scopus)

Dynamics: A key to protein function

Fuxreiter, M., Jan 1 2014, Computational Approaches to Protein Dynamics: From Quantum to Coarse-Grained Methods. CRC Press, p. 3-38 36 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Editorial overview: Dynamic protein interactions — from complexes to molecular machines

Fuxreiter, M. & Panchenko, A., Jun 2019, In : Current Opinion in Structural Biology. 56, p. vi-viii

Research output: Contribution to journalEditorial

20 Citations (Scopus)

Erratum: Correction to disordered proteinaceous machines (Chemical Reviews (2014) 114:13 (6806-6843) DOI 10.0121/cr4007329)

Fuxreiter, M., Tóth-Petróczy, Á., Kraut, D. A., Matouschek, A., Lim, R. Y. H., Xue, B., Kurgan, L. & Uversky, V. N., Apr 8 2015, In : Chemical reviews. 115, 7, 1 p.

Research output: Contribution to journalComment/debate

Evaluating boundary dependent errors in QM/MM simulations

Solt, I., Kulhánek, P., Simon, I., Winfield, S., Payne, M. C., Csányi, G. & Fuxreiter, M., Apr 30 2009, In : Journal of Physical Chemistry B. 113, 17, p. 5728-5735 8 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)

Experimental Characterization of Fuzzy Protein Assemblies: Interactions of Paramyxoviral NTAIL Domains With Their Functional Partners

Troilo, F., Bignon, C., Gianni, S., Fuxreiter, M. & Longhi, S., 2018, Methods in Enzymology. Rhoades, E. (ed.). Academic Press Inc., p. 137-192 56 p. (Methods in Enzymology; vol. 611).

Research output: Chapter in Book/Report/Conference proceedingChapter

5 Citations (Scopus)
55 Citations (Scopus)

Flexible segments modulate co-folding of dUTPase and nucleocapsid proteins

Németh-Pongrácz, V., Barabás, O., Fuxreiter, M., Simon, I., Pichová, I., Rumlová, M., Zábranská, H., Svergun, D., Petoukhov, M., Harmat, V., Klement, É., Hunyadi-Gulyás, É., Medzihradszky, K. F., Kónya, E. & Vértessy, B. G., Jan 1 2007, In : Nucleic acids research. 35, 2, p. 495-505 11 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)

Fold or not to fold upon binding — does it really matter?

Fuxreiter, M., Feb 1 2019, In : Current Opinion in Structural Biology. 54, p. 19-25 7 p.

Research output: Contribution to journalReview article

33 Citations (Scopus)
5 Citations (Scopus)
48 Citations (Scopus)

Fuzziness: Linking regulation to protein dynamics

Fuxreiter, M., Jan 1 2012, In : Molecular BioSystems. 8, 1, p. 168-177 10 p.

Research output: Contribution to journalReview article

108 Citations (Scopus)

Fuzziness enables context dependence of protein interactions

Miskei, M., Gregus, A., Sharma, R., Duro, N., Zsolyomi, F. & Fuxreiter, M., Sep 2017, In : FEBS letters. 591, 17, p. 2682-2695 14 p.

Research output: Contribution to journalReview article

23 Citations (Scopus)

Fuzziness endows viral motif-mimicry

Duro, N., Miskei, M. & Fuxreiter, M., Aug 1 2015, In : Molecular BioSystems. 11, 10, p. 2821-2829 9 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Fuzziness in Protein Interactions—A Historical Perspective

Fuxreiter, M., Aug 3 2018, In : Journal of molecular biology. 430, 16, p. 2278-2287 10 p.

Research output: Contribution to journalReview article

46 Citations (Scopus)

Fuzzy complexes: Specific binding without complete folding

Sharma, R., Raduly, Z., Miskei, M. & Fuxreiter, M., Sep 14 2015, In : FEBS letters. 589, 19, p. 2533-2542 10 p.

Research output: Contribution to journalReview article

93 Citations (Scopus)

Fuzzy complexes: A more stochastic view of protein function

Fuxreiter, M. & Tompa, P., Apr 19 2012, Fuzziness: Structural Disorder in Protein Complexes. p. 1-14 14 p. (Advances in Experimental Medicine and Biology; vol. 725).

Research output: Chapter in Book/Report/Conference proceedingChapter

131 Citations (Scopus)

Fuzzy complexes: polymorphism and structural disorder in protein-protein interactions

Tompa, P. & Fuxreiter, M., Jan 1 2008, In : Trends in Biochemical Sciences. 33, 1, p. 2-8 7 p.

Research output: Contribution to journalArticle

625 Citations (Scopus)

Fuzzy interactome: the limitations of models in molecular biology

Fuxreiter, M. & Tompa, P., Jan 1 2009, In : Trends in Biochemical Sciences. 34, 1, 1 p.

Research output: Contribution to journalLetter

8 Citations (Scopus)

Fuzzy regions in an intrinsically disordered protein impair protein-protein interactions

Gruet, A., Dosnon, M., Blocquel, D., Brunel, J., Gerlier, D., Das, R. K., Bonetti, D., Gianni, S., Fuxreiter, M., Longhi, S. & Bignon, C., Feb 1 2016, In : FEBS Journal. 283, 4, p. 576-594 19 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Genomic variants reveal differential evolutionary constraints on human transglutaminases and point towards unrecognized significance of transglutaminase 2

Thangaraju, K., Király, R., Demény, M. A., Mótyán, J. A., Fuxreiter, M. & Fésüs, L., Mar 1 2017, In : PLoS One. 12, 3, e0172189.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Highly substrate selective nucleophilic amination of nitro-substituted 4-(2-hydroxyethylamino)phthalazin-1(2H)-ones

Szabó, A., Fuxreiter, M., Csámpai, A., Körmendy, K. & Császár, J., Jan 1 1997, In : Heterocyclic Communications. 3, 6, p. 555-562 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Identification of a specific one amino acid change in recombinant human transglutaminase 2 that regulates its activity and calcium sensitivity

Kanchan, K., Ergülen, E., Király, R., Simon-Vecsei, Z., Fuxreiter, M. & Fésüs, L., Nov 1 2013, In : Biochemical Journal. 455, 3, p. 261-272 12 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Interactions via intrinsically disordered regions: What kind of motifs?

Pancsa, R. & Fuxreiter, M., Jun 1 2012, In : IUBMB life. 64, 6, p. 513-520 8 p.

Research output: Contribution to journalReview article

50 Citations (Scopus)

Interfacial water as a "hydration fingerprint" in the noncognate complex of BamHI

Fuxreiter, M., Mezei, M., Simon, I. & Osman, R., Aug 2005, In : Biophysical journal. 89, 2, p. 903-911 9 p.

Research output: Contribution to journalArticle

47 Citations (Scopus)

Intrinsically disordered proteins and their recognition functions

Uversky, V. N., Fuxreiter, M., Oldfield, C. J., Dunker, A. K. & Tompa, P., Jan 1 2009, Computational Protein-Protein Interactions. CRC Press, p. 223-252 30 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)

Intrinsically disordered segments affect protein half-life in the cell and during evolution

van der Lee, R., Lang, B., Kruse, K., Gsponer, J., de Groot, N. S., Huynen, M. A., Matouschek, A., Fuxreiter, M. & Babu, M. M., Sep 25 2014, In : Cell Reports. 8, 6, p. 1832-1844 13 p.

Research output: Contribution to journalArticle

84 Citations (Scopus)

Local structural disorder imparts plasticity on linear motifs

Fuxreiter, M., Tompa, P. & Simon, I., Apr 15 2007, In : Bioinformatics. 23, 8, p. 950-956 7 p.

Research output: Contribution to journalArticle

306 Citations (Scopus)

Malleable machines in transcription regulation: The Mediator complex

Tóth-Petróczy, Á., Oldfield, C. J., Simon, I., Takagi, Y., Dunker, A. K., Uversky, V. N. & Fuxreiter, M., Dec 2008, In : PLoS computational biology. 4, 12, e1000243.

Research output: Contribution to journalArticle

78 Citations (Scopus)

Malleable machines take shape in eukaryotic transcriptional regulation

Fuxreiter, M., Tompa, P., Simon, I., Uversky, V. N., Hansen, J. C. & Asturias, F. J., Dec 2008, In : Nature Chemical Biology. 4, 12, p. 728-737 10 p.

Research output: Contribution to journalReview article

145 Citations (Scopus)

Metal-binding sites at the active site of restriction endonuclease BamHI can conform to a one-ion mechanism

Mones, L., Simon, I. & Fuxreiter, M., Jan 1 2007, In : Biological Chemistry. 388, 1, p. 73-78 6 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
22 Citations (Scopus)