• 5409 Citations
  • 33 h-Index
19942019

Research output per year

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Research Output

1994
5 Citations (Scopus)
1995
22 Citations (Scopus)
1996

Conformation and self-association of a hybrid peptide of cecropin A and melittin with improved antibiotic activity

Fernandez, I., Ubach, J., Fuxreiter, M., Andreu, J. M., Andreu, D. & Pons, M., Jan 1 1996, In : Angewandte Chemie - International Edition in English. 35, 13-14, p. 838-846 9 p.

Research output: Contribution to journalArticle

Conformation and self-association of a hybrid peptide of cecropin A and melittin with improved antibiotic activity

Fernández, I., Ubach, J., Fuxreiter, M., Andreu, J. M., Andreu, D. & Pons, M., 1996, In : Chemistry - A European Journal. 2, 7, p. 838-846 9 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
1997

Highly substrate selective nucleophilic amination of nitro-substituted 4-(2-hydroxyethylamino)phthalazin-1(2H)-ones

Szabó, A., Fuxreiter, M., Csámpai, A., Körmendy, K. & Császár, J., Jan 1 1997, In : Heterocyclic Communications. 3, 6, p. 555-562 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Role of electrostatics at the catalytic metal binding site in xylose isomerase action: Ca2+-inhibition and metal competence in the double mutant D254E/D256E

Fuxreiter, M., Böcskei, Z., Szeibert, A., Szabó, E., Dallmann, G., Náray-Szabó, G. & Asbóth, B., Jul 14 1997, In : Proteins: Structure, Function and Genetics. 28, 2, p. 183-193 11 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)
1998

Crystallization and preliminary X-ray analysis of porcine muscle prolyl oligopeptidase

Böcskei, Z., Fuxreiter, M., Náray-Szabó, G., Szabó, E. & Polgár, L., 1998, In : Acta Crystallographica Section D: Biological Crystallography. 54, 6 PART II, p. 1414-1415 2 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Origin of the catalytic power of acetylcholinesterase: Computer simulation studies

Fuxreiter, M. & Warshel, A., Jan 14 1998, In : Journal of the American Chemical Society. 120, 1, p. 183-194 12 p.

Research output: Contribution to journalArticle

100 Citations (Scopus)
1999

Comparative redox and pK(a) calculations on cytochrome c3 from several Desulfovibrio species using continuum electrostatic methods

Martel, P. J., Soares, C. M., Baptista, A. M., Fuxreiter, M., Náray-Szabó, G., Louro, R. O. & Carrondo, M. A., Feb 1 1999, In : Journal of Biological Inorganic Chemistry. 4, 1, p. 73-86 14 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Role of active site residues in the glycosylase step of T4 Endonuclease V. Computer simulation studies on ionization states

Fuxreiter, M., Warshel, A. & Osman, R., Jul 27 1999, In : Biochemistry. 38, 30, p. 9577-9589 13 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)
2000

Specificity of damage recognition and catalysis of DNA repair

Osman, R., Fuxreiter, M. & Luo, N., Jan 1 2000, In : Computers and Chemistry. 24, 3-4, p. 331-339 9 p.

Research output: Contribution to journalConference article

22 Citations (Scopus)
2001

Checking nucleic acid crystal structures

Das, U., Chen, S., Fuxreiter, M., Vaguine, A. A., Richelle, J., Berman, H. M. & Wodak, S. J., Jul 4 2001, In : Acta Crystallographica Section D: Biological Crystallography. 57, 6, p. 813-828 16 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Probing the general base catalysis in the first step of BamHI action by computer simulations

Fuxreiter, M. & Osman, R., Dec 11 2001, In : Biochemistry. 40, 49, p. 15017-15023 7 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)
2002

Protein stability indicates divergent evolution of PD-(D/E)XK type II restriction endonucleases

Fuxreiter, M. & Simon, I., Jul 30 2002, In : Protein Science. 11, 8, p. 1978-1983 6 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Role of base flipping in specific recognition of damaged DNA by repair enzymes

Fuxreiter, M., Luo, N., Jedlovszky, P., Simon, I. & Osman, R., Jan 1 2002, In : Journal of molecular biology. 323, 5, p. 823-834 12 p.

Research output: Contribution to journalArticle

53 Citations (Scopus)

Role of stabilization centers in 4 helix bundle proteins

Fuxreiter, M. & Simon, I., Aug 1 2002, In : Proteins: Structure, Function and Genetics. 48, 2, p. 320-326 7 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

The role of hydrophobic microenvironments in modulating pKa shifts in proteins

Mehler, E. L., Fuxreiter, M., Simon, I. & Garcia-Moreno E, B., Aug 1 2002, In : Proteins: Structure, Function and Genetics. 48, 2, p. 283-292 10 p.

Research output: Contribution to journalArticle

108 Citations (Scopus)
2003

Computational approaches to restriction endonucleases

Fuxreiter, M., Osman, R. & Simon, I., Dec 29 2003, In : Journal of Molecular Structure: THEOCHEM. 666-667, p. 469-479 11 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2004
5 Citations (Scopus)

Preformed structural elements feature in partner recognition by intrinsically unstructured proteins

Fuxreiter, M., Simon, I., Friedrich, P. & Tompa, P., May 14 2004, In : Journal of molecular biology. 338, 5, p. 1015-1026 12 p.

Research output: Contribution to journalArticle

406 Citations (Scopus)
2005
55 Citations (Scopus)

Interfacial water as a "hydration fingerprint" in the noncognate complex of BamHI

Fuxreiter, M., Mezei, M., Simon, I. & Osman, R., Aug 2005, In : Biophysical journal. 89, 2, p. 903-911 9 p.

Research output: Contribution to journalArticle

47 Citations (Scopus)

Type II restriction endonucleases: Structure and mechanism

Pingoud, A., Fuxreiter, M., Pingoud, V. & Wende, W., Mar 1 2005, In : Cellular and Molecular Life Sciences. 62, 6, p. 685-707 23 p.

Research output: Contribution to journalReview article

337 Citations (Scopus)
2006
30 Citations (Scopus)
2007

An EcoRI-RsrI chimeric restriction endonuclease retains parental sequence specificity

Chuluunbaatar, T., Ivanenko-Johnston, T., Fuxreiter, M., Meleshko, R., Raskó, T., Simon, I., Heitman, J. & Kiss, A., May 1 2007, In : Biochimica et Biophysica Acta - Proteins and Proteomics. 1774, 5, p. 583-594 12 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
20 Citations (Scopus)

Flexible segments modulate co-folding of dUTPase and nucleocapsid proteins

Németh-Pongrácz, V., Barabás, O., Fuxreiter, M., Simon, I., Pichová, I., Rumlová, M., Zábranská, H., Svergun, D., Petoukhov, M., Harmat, V., Klement, É., Hunyadi-Gulyás, É., Medzihradszky, K. F., Kónya, E. & Vértessy, B. G., Jan 1 2007, In : Nucleic acids research. 35, 2, p. 495-505 11 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)

Local structural disorder imparts plasticity on linear motifs

Fuxreiter, M., Tompa, P. & Simon, I., Apr 15 2007, In : Bioinformatics. 23, 8, p. 950-956 7 p.

Research output: Contribution to journalArticle

306 Citations (Scopus)

Metal-binding sites at the active site of restriction endonuclease BamHI can conform to a one-ion mechanism

Mones, L., Simon, I. & Fuxreiter, M., Jan 1 2007, In : Biological Chemistry. 388, 1, p. 73-78 6 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Probing the two-metal ion mechanism in the restriction endonuclease BamHI

Mones, L., Kulhánek, P., Florián, J., Simon, I. & Fuxreiter, M., Dec 18 2007, In : Biochemistry. 46, 50, p. 14514-14523 10 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)
2008

Fuzzy complexes: polymorphism and structural disorder in protein-protein interactions

Tompa, P. & Fuxreiter, M., Jan 1 2008, In : Trends in Biochemical Sciences. 33, 1, p. 2-8 7 p.

Research output: Contribution to journalArticle

625 Citations (Scopus)

Malleable machines in transcription regulation: The Mediator complex

Tóth-Petróczy, Á., Oldfield, C. J., Simon, I., Takagi, Y., Dunker, A. K., Uversky, V. N. & Fuxreiter, M., Dec 2008, In : PLoS computational biology. 4, 12, e1000243.

Research output: Contribution to journalArticle

78 Citations (Scopus)

Malleable machines take shape in eukaryotic transcriptional regulation

Fuxreiter, M., Tompa, P., Simon, I., Uversky, V. N., Hansen, J. C. & Asturias, F. J., Dec 2008, In : Nature Chemical Biology. 4, 12, p. 728-737 10 p.

Research output: Contribution to journalReview article

145 Citations (Scopus)
2009

Close encounters of the third kind: Disordered domains and the interactions of proteins

Tompa, P., Fuxreiter, M., Oldfield, C. J., Simon, I., Dunker, A. K. & Uversky, V. N., Apr 27 2009, In : BioEssays. 31, 3, p. 328-335 8 p.

Research output: Contribution to journalArticle

181 Citations (Scopus)

Disordered tails of homeodomains facilitate DNA recognition by providing a trade-off between folding and specific binding

Tóth-Petróczy, Á., Simon, I., Fuxreiter, M. & Levy, Y., Oct 28 2009, In : Journal of the American Chemical Society. 131, 42, p. 15084-15085 2 p.

Research output: Contribution to journalArticle

53 Citations (Scopus)

Evaluating boundary dependent errors in QM/MM simulations

Solt, I., Kulhánek, P., Simon, I., Winfield, S., Payne, M. C., Csányi, G. & Fuxreiter, M., Apr 30 2009, In : Journal of Physical Chemistry B. 113, 17, p. 5728-5735 8 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)

Fuzzy interactome: the limitations of models in molecular biology

Fuxreiter, M. & Tompa, P., Jan 1 2009, In : Trends in Biochemical Sciences. 34, 1, 1 p.

Research output: Contribution to journalLetter

8 Citations (Scopus)

Intrinsically disordered proteins and their recognition functions

Uversky, V. N., Fuxreiter, M., Oldfield, C. J., Dunker, A. K. & Tompa, P., Jan 1 2009, Computational Protein-Protein Interactions. CRC Press, p. 223-252 30 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)

On the Divalent Metal Ion Dependence of DNA Cleavage by Restriction Endonucleases of the EcoRI Family

Pingoud, V., Wende, W., Friedhoff, P., Reuter, M., Alves, J., Jeltsch, A., Mones, L., Fuxreiter, M. & Pingoud, A., Oct 16 2009, In : Journal of molecular biology. 393, 1, p. 140-160 21 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)

The energy gap as a universal reaction coordinate for the simulation of chemical reactions

Mones, L., Kulhánek, P., Simon, I., Laio, A. & Fuxreiter, M., Jun 4 2009, In : Journal of Physical Chemistry B. 113, 22, p. 7867-7873 7 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)
2011

Active site residue involvement in monoamine or diamine oxidation catalysed by pea seedling amine oxidase

Di Paolo, M. L., Lunelli, M., Fuxreiter, M., Rigo, A., Simon, I. & Scarpa, M., Apr 1 2011, In : FEBS Journal. 278, 8, p. 1232-1243 12 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Dynamic protein-DNA recognition: Beyond what can be seen

Fuxreiter, M., Simon, I. & Bondos, S., Aug 1 2011, In : Trends in Biochemical Sciences. 36, 8, p. 415-423 9 p.

Research output: Contribution to journalReview article

104 Citations (Scopus)
2012

Fuzziness: Linking regulation to protein dynamics

Fuxreiter, M., Jan 1 2012, In : Molecular BioSystems. 8, 1, p. 168-177 10 p.

Research output: Contribution to journalReview article

108 Citations (Scopus)

Fuzzy complexes: A more stochastic view of protein function

Fuxreiter, M. & Tompa, P., Apr 19 2012, Fuzziness: Structural Disorder in Protein Complexes. p. 1-14 14 p. (Advances in Experimental Medicine and Biology; vol. 725).

Research output: Chapter in Book/Report/Conference proceedingChapter

131 Citations (Scopus)

Interactions via intrinsically disordered regions: What kind of motifs?

Pancsa, R. & Fuxreiter, M., Jun 1 2012, In : IUBMB life. 64, 6, p. 513-520 8 p.

Research output: Contribution to journalReview article

50 Citations (Scopus)

Preface

Fuxreiter, M. & Tompa, P., Apr 19 2012, Fuzziness: Structural Disorder in Protein Complexes. p. ix-xiii (Advances in Experimental Medicine and Biology; vol. 725).

Research output: Chapter in Book/Report/Conference proceedingForeword/postscript

4 Citations (Scopus)

QM/MM simulation of liquid water with an adaptive quantum region

Bernstein, N., Várnai, C., Solt, I., Winfield, S. A., Payne, M. C., Simon, I., Fuxreiter, M. & Csányi, G., Jan 14 2012, In : Physical Chemistry Chemical Physics. 14, 2, p. 646-656 11 p.

Research output: Contribution to journalArticle

61 Citations (Scopus)

Tissue-Specific Splicing of Disordered Segments that Embed Binding Motifs Rewires Protein Interaction Networks

Buljan, M., Chalancon, G., Eustermann, S., Wagner, G. P., Fuxreiter, M., Bateman, A. & Babu, M. M., Jun 29 2012, In : Molecular Cell. 46, 6, p. 871-883 13 p.

Research output: Contribution to journalArticle

226 Citations (Scopus)
2013

Alternative splicing of intrinsically disordered regions and rewiring of protein interactions

Buljan, M., Chalancon, G., Dunker, A. K., Bateman, A., Balaji, S., Fuxreiter, M. & Babu, M. M., Jun 1 2013, In : Current Opinion in Structural Biology. 23, 3, p. 443-450 8 p.

Research output: Contribution to journalReview article

100 Citations (Scopus)

Identification of a specific one amino acid change in recombinant human transglutaminase 2 that regulates its activity and calcium sensitivity

Kanchan, K., Ergülen, E., Király, R., Simon-Vecsei, Z., Fuxreiter, M. & Fésüs, L., Nov 1 2013, In : Biochemical Journal. 455, 3, p. 261-272 12 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)