• 14989 Citations
  • 50 h-Index
1991 …2020

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

Filter
Article
Article

1,25-Dihydroxyvitamin D3 Is an autonomous regulator of the transcriptional changes leading to a tolerogenic dendritic cell phenotype

Széles, L., Keresztes, G., Töröcsik, D., Balajthy, Z., Krenács, L., Póliska, S., Steinmeyer, A., Zuegel, U., Pruenster, M., Rot, A. & Nagy, L., Feb 15 2009, In : Journal of Immunology. 182, 4, p. 2074-2083 10 p.

Research output: Contribution to journalArticle

141 Citations (Scopus)

9-cis-13,14-Dihydroretinoic Acid Is an Endogenous Retinoid Acting as RXR Ligand in Mice

Rühl, R., Krzyżosiak, A., Niewiadomska-Cimicka, A., Rochel, N., Szeles, L., Vaz, B., Wietrzych-Schindler, M., Álvarez, S., Szklenar, M., Nagy, L., de Lera, A. R. & Krężel, W., Jul 1 2015, In : PLoS genetics. 11, 6, e1005213.

Research output: Contribution to journalArticle

51 Citations (Scopus)

Accelerated recovery of 5-fluorouracil-damaged bone marrow after rosiglitazone treatment

Djazayeri, K., Szilvássy, Z., Peitl, B., Németh, J., Nagy, L., Kiss, A., Szabó, B. & Benko, I., Oct 17 2005, In : European Journal of Pharmacology. 522, 1-3, p. 122-129 8 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Activation of liver X receptor sensitizes human dendritic cells to inflammatory stimuli

Töröcsik, D., Baráth, M., Benko, S., Széles, L., Dezso, B., Póliska, S., Hegyi, Z., Homolya, L., Szatmári, I., Lányi, Á. & Nagy, L., May 15 2010, In : Journal of Immunology. 184, 10, p. 5456-5465 10 p.

Research output: Contribution to journalArticle

47 Citations (Scopus)
118 Citations (Scopus)

Activation of retinoic acid receptor signaling coordinates lineage commitment of spontaneously differentiating mouse embryonic stem cells in embryoid bodies

Simandi, Z., Balint, B. L., Poliska, S., Ruhl, R. & Nagy, L., Jul 1 2010, In : FEBS letters. 584, 14, p. 3123-3130 8 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Activation of retinoid X receptors induces apoptosis in HL-60 cell lines

Nagy, L., Thomázy, V. A., Shipley, G. L., Fésüs, L., Lamph, W., Heyman, R. A., Chandraratna, R. A. S. & Davies, P. J. A., Jul 1995, In : Molecular and cellular biology. 15, 7, p. 3540-3551 12 p.

Research output: Contribution to journalArticle

Open Access
235 Citations (Scopus)

A funkcionális genomikai eszköztár szerepe az onkológiai kutatásokban

Translated title of the contribution: The place of functional genomics in oncological researchBálint, B. L. & László, N., 2013, In : Magyar onkologia. 57, 1, p. 21-25 5 p.

Research output: Contribution to journalArticle

Analyses of association between PPAR gamma and EPHX1 polymorphisms and susceptibility to COPD in a Hungarian cohort, a case-control study

Penyige, A., Poliska, S., Csanky, E., Scholtz, B., Dezso, B., Schmelczer, I., Kilty, I., Takacs, L. & Nagy, L., Nov 4 2010, In : BMC Medical Genetics. 11, 1, 152.

Research output: Contribution to journalArticle

21 Citations (Scopus)

A novel method to predict regulatory regions based on histone mark landscapes in macrophages

Nagy, G., Dániel, B., Jónás, D., Nagy, L. & Barta, E., Nov 1 2013, In : Immunobiology. 218, 11, p. 1416-1427 12 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

A pharmacogenetic approach to the treatment of patients with PPARG mutations

Agostini, M., Schoenmakers, E., Beig, J., Fairall, L., Szatmari, I., Rajanayagam, O., Muskett, F. W., Adams, C., Marais, A. D., O’Rahilly, S., Semple, R. K., Nagy, L., Majithia, A. R., Schwabe, J. W. R., Blom, D. J., Murphy, R., Chatterjee, K. & Savage, D. B., Jun 1 2018, In : Diabetes. 67, 6, p. 1086-1092 7 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Apoptosis-linked in vivo regulation of the tissue transglutaminase gene promoter

Szegezdi, É., Szondy, Z., Nagy, L., Nemes, Z., Friis, R. R., Davies, P. J. A. & Fésüs, L., Dec 1 2000, In : Cell Death and Differentiation. 7, 12, p. 1225-1233 9 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

A PPARγ-LXR-ABCA1 pathway in macrophages is involved in cholesterol efflux and atherogenesis

Chawla, A., Boisvert, W. A., Lee, C. H., Laffitte, B. A., Barak, Y., Joseph, S. B., Liao, D., Nagy, L., Edwards, P. A., Curtiss, L. K., Evans, R. M. & Tontonoz, P., Jan 1 2001, In : Molecular Cell. 7, 1, p. 161-171 11 p.

Research output: Contribution to journalArticle

1037 Citations (Scopus)

Arginine methylation provides epigenetic transcription memory for retinoid-induced differentiation in myeloid cells

Balint, B. L., Szanto, A., Madi, A., Bauer, U. M., Gabor, P., Benko, S., Puskás, L. G., Davies, P. J. A. & Nagy, L., Jul 2005, In : Molecular and cellular biology. 25, 13, p. 5648-5663 16 p.

Research output: Contribution to journalArticle

45 Citations (Scopus)

Arginine methyltransferase PRMT8 provides cellular stress tolerance in aging motoneurons

Simandi, Z., Pajer, K., Karolyi, K., Sieler, T., Jiang, L. L., Kolostyak, Z., Sari, Z., Fekecs, Z., Pap, A., Patsalos, A., Contreras, G. A., Reho, B., Papp, Z., Guo, X., Horvath, A., Kiss, G., Keresztessy, Z., Vámosi, G., Hickman, J., Xu, H. & 5 others, Dormann, D., Hortobagyi, T., Antal, M., Nógrádi, A. & Nagy, L., Aug 29 2018, In : Journal of Neuroscience. 38, 35, p. 7683-7700 18 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
12 Citations (Scopus)

A szkizofrénia multilókusz genetikai vizsgálata az idegfejlödés és az immunrendszer zavarának oki szerepére utal(hat)

Translated title of the contribution: Multilocus genetic analysis implicates neurodevelopment and immune system in the etiology of schizophreniaPulay, A. J., Koller, J., Nagy, L., Molnár, M. J. & Réthelyi, J., Mar 30 2017, In : Ideggyogyaszati Szemle. 70, 3-4, p. 115-126 12 p.

Research output: Contribution to journalArticle

Atherosclerosis and lipid peroxidation

Nagy, L. & Spiteller, G., Nov 1 2005, In : Molecular Nutrition and Food Research. 49, 11, p. 989-991 3 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

A Versatile Method to Design Stem-Loop Primer-Based Quantitative PCR Assays for Detecting Small Regulatory RNA Molecules

Czimmerer, Z., Hulvely, J., Simandi, Z., Varallyay, E., Havelda, Z., Szabo, E., Varga, A., Dezso, B., Balogh, M., Horvath, A., Domokos, B., Torok, Z., Nagy, L. & Balint, B. L., Jan 31 2013, In : PloS one. 8, 1, e55168.

Research output: Contribution to journalArticle

57 Citations (Scopus)

Carboxypeptidase-M is regulated by lipids and CSFs in macrophages and dendritic cells and expressed selectively in tissue granulomas and foam cells

Tsakiris, I., Torocsik, D., Gyongyosi, A., Dozsa, A., Szatmari, I., Szanto, A., Soos, G., Nemes, Z., Igali, L., Marton, I., Takats, Z., Nagy, L. & Dezso, B., Mar 1 2012, In : Laboratory Investigation. 92, 3, p. 345-361 17 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

ChIP-on-beads: Flow-cytometric evaluation of chromatin immunoprecipitation

Székvölgyi, L., Bálint, B. L., Imre, L., Goda, K., Szabó, M., Nagy, L. & Szabó, G., Oct 1 2006, In : Cytometry Part A. 69, 10, p. 1086-1091 6 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Chronic obstructive pulmonary disease-specific gene expression signatures of alveolar macrophages as well as peripheral blood monocytes overlap and correlate with lung function

Poliska, S., Csanky, E., Szanto, A., Szatmari, I., Mesko, B., Szeles, L., Dezso, B., Scholtz, B., Podani, J., Kilty, I., Takacs, L. & Nagy, L., May 1 2011, In : Respiration. 81, 6, p. 499-510 12 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

CLA-supplemented diet accelerates experimental colorectal cancer by inducing TGF-β-producing macrophages and T cells

Moreira, T. G., Horta, L. S., Gomes-Santos, A. C., Oliveira, R. P., Queiroz, N. M. G. P., Mangani, D., Daniel, B., Vieira, A. T., Liu, S., Rodrigues, A. M., Gomes, D. A., Gabriely, G., Ferreira, E., Weiner, H. L., Rezende, R. M., Nagy, L. & Faria, A. M. C., Jan 1 2019, In : Mucosal Immunology. 12, 1, p. 188-199 12 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
17 Citations (Scopus)

Combination of IgG N-glycomics and corresponding transcriptomics data to identify anti-TNF-α treatment responders in inflammatory diseases

Váradi, C., Holló, Z., Póliska, S., Nagy, L., Szekanecz, Z., Váncsa, A., Palatka, K. & Guttman, A., Jun 1 2015, In : ELECTROPHORESIS. 36, 11-12, p. 1330-1335 6 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Consumption of conjugated linoleic acid (CLA)-supplemented diet during colitis development ameliorates gut inflammation without causing steatosis in mice

Moreira, T. G., Gomes-Santos, A. C., Horta, L. S., Goncalves, M. C., Santiago, A. F., Lauar, J. G., dos Reis, D. S., Castro-Junior, A. B., Lemos, L., Guimarães, M., Aguilar, E. C., Pap, A., Amaral, J. F., Alvarez-Leite, J. I., Cara, D. C., Rezende, R. M., Nagy, L., Faria, A. M. C. & Maioli, T. U., Jul 2018, In : Journal of Nutritional Biochemistry. 57, p. 238-245 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Decreased peroxisome proliferator-activated receptor γ level and signalling in sebaceous glands of patients with acne vulgaris

Dozsa, A., Mihaly, J., Dezső, B., Csizmadia, E., Keresztessy, T., Marko, L., Rühl, R., Remenyik, E. & Nagy, L., Jul 1 2016, In : Clinical and Experimental Dermatology. 41, 5, p. 547-551 5 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Differential effects of rexinoids and thiazolidinediones on metabolic gene expression in diabetic rodents

Ahuja, H. S., Liu, S., Crombie, D. L., Boehm, M., Leibowitz, M. D., Heyman, R. A., Depre, C., Nagy, L., Tontonoz, P. & Davies, P. J. A., Jan 1 2001, In : Molecular pharmacology. 59, 4, p. 765-773 9 p.

Research output: Contribution to journalArticle

101 Citations (Scopus)
90 Citations (Scopus)

Dynamic changes to lipid mediators support transitions among macrophage subtypes during muscle regeneration

Giannakis, N., Sansbury, B. E., Patsalos, A., Hays, T. T., Riley, C. O., Han, X., Spite, M. & Nagy, L., May 1 2019, In : Nature Immunology. 20, 5, p. 626-636 11 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Dynamic transcriptional control of macrophage miRNA signature via inflammation responsive enhancers revealed using a combination of next generation sequencing-based approaches

Czimmerer, Z., Horvath, A., Daniel, B., Nagy, G., Cuaranta-Monroy, I., Kiss, M., Kolostyak, Z., Poliska, S., Steiner, L., Giannakis, N., Varga, T. & Nagy, L., Jan 2018, In : Biochimica et Biophysica Acta - Gene Regulatory Mechanisms. 1861, 1, p. 14-28 15 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Endocannabinoids enhance lipid synthesis and apoptosis of human sebocytes via cannabinoid receptor-2-mediated signaling

Dobrosi, N., Tóth, B. I., Nagy, G., Dózsa, A., Géczy, T., Nagy, L., Zouboulis, C. C., Paus, R., Kovács, L. & Bíró, T., Oct 2008, In : FASEB Journal. 22, 10, p. 3685-3695 11 p.

Research output: Contribution to journalArticle

88 Citations (Scopus)

Erratum: PPARγ activation but not PPARγ haplodeficiency affects proangiogenic potential of endothelial cells and bone marrow-derived progenitors [Cardiovasc Diabetol 13, (2014), 150]

Kotlinowski, J., Grochot-Przeczek, A., Taha, H., Kozakowska, M., Pilecki, B., Skrzypek, K., Zimoch, J., Bartelik, A., Derlacz, R., Horrevoets, A. J., Pap, A., Nagy, L., Dulak, J. & Jozkowicz, A., May 29 2015, In : Cardiovascular diabetology. 14, 1, 65.

Research output: Contribution to journalArticle

Essential roles of retinoic acid signaling in interdigital apoptosis and control of BMP-7 expression in mouse autopods

Dupé, V., Ghyselinck, N. B., Thomazy, V., Nagy, L., Davies, P. J. A., Chambon, P. & Mark, M., Apr 1 1999, In : Developmental Biology. 208, 1, p. 30-43 14 p.

Research output: Contribution to journalArticle

91 Citations (Scopus)

Ethanol increases phosphate-mediated mineralization and osteoblastic transformation of vascular smooth muscle cells

Oros, M., Zavaczki, E., Vadasz, C., Jeney, V., Tosaki, A., Lekli, I., Balla, G., Nagy, L. & Balla, J., Sep 1 2012, In : Journal of Cellular and Molecular Medicine. 16, 9, p. 2219-2226 8 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Extensive and functional overlap of the STAT6 and RXR cistromes in the active enhancer repertoire of human CD14+ monocyte derived differentiating macrophages

Czimmerer, Z., Nagy, Z. S., Nagy, G., Horvath, A., Silye-Cseh, T., Kriston, A., Jonas, D., Sauer, S., Steiner, L., Daniel, B., Deleuze, J. F. & Nagy, L., Aug 15 2018, In : Molecular and Cellular Endocrinology. 471, p. 63-74 12 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
21 Citations (Scopus)

Functional ABCG1 expression induces apoptosis in macrophages and other cell types

Seres, L., Cserepes, J., Elkind, N. B., Törocsik, D., Nagy, L., Sarkadi, B. & Homolya, L., Oct 1 2008, In : Biochimica et Biophysica Acta - Biomembranes. 1778, 10, p. 2378-2387 10 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Gene expression analysis of vascular pathophysiology related to anti-TNF treatment in rheumatoid arthritis

Póliska, S., Besenyei, T., Végh, E., Hamar, A., Pusztai, A., Váncsa, A., Bodnár, N., Szamosi, S., Csumita, M., Kerekes, G., Szabó, Z., Nagy, Z., Szucs, G., Szántó, S., Zahuczky, G., Nagy, L. & Szekanecz, Z., Apr 15 2019, In : Arthritis Research and Therapy. 21, 1, 94.

Research output: Contribution to journalArticle

Open Access
6 Citations (Scopus)

Genomewide effects of peroxisome proliferator-activated receptor gamma in macrophages and dendritic cells - Revealing complexity through systems biology

Cuaranta-Monroy, I., Kiss, M., Simandi, Z. & Nagy, L., Sep 1 2015, In : European Journal of Clinical Investigation. 45, 9, p. 964-975 12 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Genome-wide localization of histone 4 arginine 3 methylation in a differentiation primed myeloid leukemia cell line

Balint, B. L., Gabor, P. & Nagy, L., Aug 19 2005, In : Immunobiology. 210, 2-4, p. 141-152 12 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Genome Wide Mapping Reveals PDE4B as an IL-2 Induced STAT5 Target Gene in Activated Human PBMCs and Lymphoid Cancer Cells

Nagy, Z. S., Ross, J. A., Rodriguez, G., Balint, B. L., Szeles, L., Nagy, L. & Kirken, R. A., Feb 25 2013, In : PloS one. 8, 2, e57326.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Glucocorticoids counteract hypertrophic effects of myostatin inhibition in dystrophic muscle

Hammers, D. W., Hart, C. C., Patsalos, A., Matheny, M. K., Wright, L. A., Nagy, L. & Sweeney, H. L., Jan 1 2020, In : JCI Insight. 5, 1, e133276.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Hepatocyte-Macrophage Acetoacetate Shuttle Protects against Tissue Fibrosis

Puchalska, P., Martin, S. E., Huang, X., Lengfeld, J. E., Daniel, B., Graham, M. J., Han, X., Nagy, L., Patti, G. J. & Crawford, P. A., Feb 5 2019, In : Cell Metabolism. 29, 2, p. 383-398.e7

Research output: Contribution to journalArticle

10 Citations (Scopus)

Highly dynamic transcriptional signature of distinct macrophage subsets during sterile inflammation, resolution, and tissue repair

Varga, T., Mounier, R., Horvath, A., Cuvellier, S., Dumont, F., Poliska, S., Ardjoune, H., Juban, G., Nagy, L. & Chazaud, B., Jun 1 2016, In : Journal of Immunology. 196, 11, p. 4771-4782 12 p.

Research output: Contribution to journalArticle

57 Citations (Scopus)

Highly efficient differentiation of embryonic stem cells into adipocytes by ascorbic acid

Cuaranta-Monroy, I., Simandi, Z., Kolostyak, Z., Doan-Xuan, Q. M., Poliska, S., Horvath, A., Nagy, G., Bacso, Z. & Nagy, L., Jul 2014, In : Stem Cell Research. 13, 1, p. 88-97 10 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Hmgb1 can facilitate activation of the matrilin-1 gene promoter by Sox9 and L-Sox5/Sox6 in early steps of chondrogenesis

Szénási, T., Kénesi, E., Nagy, A., Molnár, A., Bálint, B. L., Zvara, G., Csabai, Z., Deák, F., Boros Oláh, B., Mátés, L., Nagy, L., Puskás, L. G. & Kiss, I., Oct 1 2013, In : Biochimica et Biophysica Acta - Gene Regulatory Mechanisms. 1829, 10, p. 1075-1091 17 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Identification and characterization of a novel anti-inflammatory lipid isolated from Mycobacterium vaccae, a soil-derived bacterium with immunoregulatory and stress resilience properties

Smith, D. G., Martinelli, R., Besra, G. S., Illarionov, P. A., Szatmari, I., Brazda, P., Allen, M. A., Xu, W., Wang, X., Nagy, L., Dowell, R. D., Rook, G. A. W., Rosa Brunet, L. & Lowry, C. A., May 1 2019, In : Psychopharmacology. 236, 5, p. 1653-1670 18 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Identification and characterization of a versatile retinoid response element (retinoic acid receptor response element-retinoid X receptor response element) in the mouse tissue transglutaminase gene promoter

Nagy, L., Saydak, M., Shipley, N., Lu, S., Basilion, J. P., Yan, Z. H., Syka, P., Chandraratna, R. A. S., Stein, J. P., Heyman, R. A. & Davies, P. J. A., Feb 23 1996, In : Journal of Biological Chemistry. 271, 8, p. 4355-4365 11 p.

Research output: Contribution to journalArticle

Open Access
123 Citations (Scopus)
71 Citations (Scopus)