• 14989 Citations
  • 50 h-Index
1991 …2020

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Article
1991

Retinoic acid receptor transcripts in human umbilical vein endothelial cells

Fesus, L., Nagy, L., Basilion, J. P. & Davies, P. J. A., Aug 30 1991, In : Biochemical and biophysical research communications. 179, 1, p. 32-38 7 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
1995

Activation of retinoid X receptors induces apoptosis in HL-60 cell lines

Nagy, L., Thomázy, V. A., Shipley, G. L., Fésüs, L., Lamph, W., Heyman, R. A., Chandraratna, R. A. S. & Davies, P. J. A., Jul 1995, In : Molecular and cellular biology. 15, 7, p. 3540-3551 12 p.

Research output: Contribution to journalArticle

Open Access
235 Citations (Scopus)
1996

Identification and characterization of a versatile retinoid response element (retinoic acid receptor response element-retinoid X receptor response element) in the mouse tissue transglutaminase gene promoter

Nagy, L., Saydak, M., Shipley, N., Lu, S., Basilion, J. P., Yan, Z. H., Syka, P., Chandraratna, R. A. S., Stein, J. P., Heyman, R. A. & Davies, P. J. A., Feb 23 1996, In : Journal of Biological Chemistry. 271, 8, p. 4355-4365 11 p.

Research output: Contribution to journalArticle

Open Access
123 Citations (Scopus)

Retinoic acid induction of the tissue transglutaminase promoter is mediated by a novel response element

Yan, Z. H., Noonan, S., Nagy, L., Davies, P. J. A. & Stein, J. P., Jul 1 1996, In : Molecular and Cellular Endocrinology. 120, 2, p. 203-212 10 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Retinoid-regulated expression of BCL-2 and tissue transglutaminase during the differentiation and apoptosis of human myeloid leukemia (HL-60) cells

Nagy, L., Thomázy, V. A., Chandraratna, R. A. S., Heyman, R. A. & Davies, P. J. A., Jun 1996, In : Leukemia Research. 20, 6, p. 499-505 7 p.

Research output: Contribution to journalArticle

48 Citations (Scopus)
1997
9 Citations (Scopus)

Nuclear receptor coactivator ACTR is a novel histone acetyltransferase and forms a multimeric activation complex with P/CAF and CBP/p300

Chen, H., Lin, R. J., Schiltz, R. L., Chakravarti, D., Nash, A., Nagy, L., Privalsky, M. L., Nakatani, Y. & Evans, R. M., Aug 8 1997, In : Cell. 90, 3, p. 569-580 12 p.

Research output: Contribution to journalArticle

1209 Citations (Scopus)

Nuclear receptor repression mediated by a complex containing SMRT, mSin3A, and histone deacetylase

Nagy, L., Kao, H. Y., Chakravarti, D., Lin, R. J., Hassig, C. A., Ayer, D. E., Schreiber, S. L. & Evans, R. M., May 2 1997, In : Cell. 89, 3, p. 373-380 8 p.

Research output: Contribution to journalArticle

1066 Citations (Scopus)

The promoter of the mouse tissue transglutaminase gene directs tissue-specific, retinoid-regulated and apoptosis-linked expression

Nagy, L., Thomázy, V. A., Saydak, M. M., Stein, J. P. & Davies, P. J. A., Jan 1 1997, In : Cell Death and Differentiation. 4, 7, p. 534-547 14 p.

Research output: Contribution to journalArticle

Open Access
53 Citations (Scopus)
1998

Oxidized LDL regulates macrophage gene expression through ligand activation of PPARγ

Nagy, L., Tontonoz, P., Alvarez, J. G. A., Chen, H. & Evans, R. M., Apr 17 1998, In : Cell. 93, 2, p. 229-240 12 p.

Research output: Contribution to journalArticle

1466 Citations (Scopus)

PPARγ promotes monocyte/macrophage differentiation and uptake of oxidized LDL

Tontonoz, P., Nagy, L., Alvarez, J. G. A., Thomazy, V. A. & Evans, R. M., Apr 17 1998, In : Cell. 93, 2, p. 241-252 12 p.

Research output: Contribution to journalArticle

1513 Citations (Scopus)

Role of the histone deacetylase complex in acute promyelocytic leukaemia

Lin, R. J., Nagy, L., Inoue, S., Shao, W., Miller, J. & Evans, R. M., Feb 19 1998, In : Nature. 391, 6669, p. 811-814 4 p.

Research output: Contribution to journalArticle

949 Citations (Scopus)

TNF-α modulates expression of the tissue transglutaminase gene in liver cells

Kuncio, G. S., Tsyganskaya, M., Zhu, J., Liu, S. L., Nagy, L., Thomazy, V., Davies, P. J. A. & Zern, M. A., Jan 1 1998, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 274, 2 37-2, p. G240-G245

Research output: Contribution to journalArticle

92 Citations (Scopus)
1999

Essential roles of retinoic acid signaling in interdigital apoptosis and control of BMP-7 expression in mouse autopods

Dupé, V., Ghyselinck, N. B., Thomazy, V., Nagy, L., Davies, P. J. A., Chambon, P. & Mark, M., Apr 1 1999, In : Developmental Biology. 208, 1, p. 30-43 14 p.

Research output: Contribution to journalArticle

91 Citations (Scopus)

Mechanism of corepressor binding and release from nuclear hormone receptors

Nagy, L., Kao, H. Y., Love, J. D., Li, C., Banayo, E., Gooch, J. T., Krishna, V., Chatterjee, K., Evans, R. M. & Schwabe, J. W. R., Dec 15 1999, In : Genes and Development. 13, 24, p. 3209-3216 8 p.

Research output: Contribution to journalArticle

326 Citations (Scopus)
2000

Apoptosis-linked in vivo regulation of the tissue transglutaminase gene promoter

Szegezdi, É., Szondy, Z., Nagy, L., Nemes, Z., Friis, R. R., Davies, P. J. A. & Fésüs, L., Dec 1 2000, In : Cell Death and Differentiation. 7, 12, p. 1225-1233 9 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

Role for peroxisome proliferator-activated receptor α in oxidized phospholipid-induced synthesis of monocyte chemotactic protein-1 interleukin-8 by endothelial cells

Lee, H., Shi, W., Tontonoz, P., Wang, S., Subbanagounder, G., Hedrick, C. C., Hama, S., Borromeo, C., Evans, R. M., Berliner, J. A. & Nagy, L., Sep 15 2000, In : Circulation research. 87, 6, p. 516-521 6 p.

Research output: Contribution to journalArticle

Open Access
258 Citations (Scopus)

Transcriptional repression by nuclear receptors: Mechanisms and role in disease

Love, J. D., Gooch, J. T., Nagy, L., Chatterjee, V. K. K. & Schwabe, J. W. R., Jan 1 2000, In : Biochemical Society transactions. 28, 4, p. 390-396 7 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)
2001

A PPARγ-LXR-ABCA1 pathway in macrophages is involved in cholesterol efflux and atherogenesis

Chawla, A., Boisvert, W. A., Lee, C. H., Laffitte, B. A., Barak, Y., Joseph, S. B., Liao, D., Nagy, L., Edwards, P. A., Curtiss, L. K., Evans, R. M. & Tontonoz, P., Jan 1 2001, In : Molecular Cell. 7, 1, p. 161-171 11 p.

Research output: Contribution to journalArticle

1037 Citations (Scopus)

Differential effects of rexinoids and thiazolidinediones on metabolic gene expression in diabetic rodents

Ahuja, H. S., Liu, S., Crombie, D. L., Boehm, M., Leibowitz, M. D., Heyman, R. A., Depre, C., Nagy, L., Tontonoz, P. & Davies, P. J. A., Jan 1 2001, In : Molecular pharmacology. 59, 4, p. 765-773 9 p.

Research output: Contribution to journalArticle

101 Citations (Scopus)

PPAR-γ dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation

Chawla, A., Barak, Y., Nagy, L., Liao, D., Tontonoz, P. & Evans, R. M., Feb 5 2001, In : Nature medicine. 7, 1, p. 48-52 5 p.

Research output: Contribution to journalArticle

904 Citations (Scopus)
2002

The structural basis for the specificity of retinoid-X receptor-selective agonists: New insights into the role of helix H12

Love, J. D., Gooch, J. T., Benko, S., Li, C., Nagy, L., Krishna K Chatterjee, V., Evans, R. M. & Schwabe, J. W. R., Mar 29 2002, In : Journal of Biological Chemistry. 277, 13, p. 11385-11391 7 p.

Research output: Contribution to journalArticle

62 Citations (Scopus)
2003

Molecular Determinants of the Balance between Co-repressor and Co-activator Recruitment to the Retinoic Acid Receptor

Benko, S., Love, J. D., Beládi, M., Schwabe, J. W. R. & Nagy, L., Oct 31 2003, In : Journal of Biological Chemistry. 278, 44, p. 43797-43806 10 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)
2004
118 Citations (Scopus)

Transcriptional regulation of human CYP27 integrates retinoid, peroxisome proliferator-activated receptor, and liver X receptor signaling in macrophages

Szanto, A., Benko, S., Szatmari, I., Balint, B. L., Furtos, I., Rühl, R., Molnar, S., Csiba, L., Garuti, R., Calandra, S., Larsson, H., Diczfalusy, U. & Nagy, L., Sep 2004, In : Molecular and cellular biology. 24, 18, p. 8154-8166 13 p.

Research output: Contribution to journalArticle

97 Citations (Scopus)
2005

Accelerated recovery of 5-fluorouracil-damaged bone marrow after rosiglitazone treatment

Djazayeri, K., Szilvássy, Z., Peitl, B., Németh, J., Nagy, L., Kiss, A., Szabó, B. & Benko, I., Oct 17 2005, In : European Journal of Pharmacology. 522, 1-3, p. 122-129 8 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Arginine methylation provides epigenetic transcription memory for retinoid-induced differentiation in myeloid cells

Balint, B. L., Szanto, A., Madi, A., Bauer, U. M., Gabor, P., Benko, S., Puskás, L. G., Davies, P. J. A. & Nagy, L., Jul 2005, In : Molecular and cellular biology. 25, 13, p. 5648-5663 16 p.

Research output: Contribution to journalArticle

45 Citations (Scopus)

Atherosclerosis and lipid peroxidation

Nagy, L. & Spiteller, G., Nov 1 2005, In : Molecular Nutrition and Food Research. 49, 11, p. 989-991 3 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
17 Citations (Scopus)

Genome-wide localization of histone 4 arginine 3 methylation in a differentiation primed myeloid leukemia cell line

Balint, B. L., Gabor, P. & Nagy, L., Aug 19 2005, In : Immunobiology. 210, 2-4, p. 141-152 12 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
71 Citations (Scopus)
43 Citations (Scopus)

Roles for lipid-activated transcription factors in atherosclerosis

Nagy, L. & Szanto, A., Nov 1 2005, In : Molecular Nutrition and Food Research. 49, 11, p. 1072-1074 3 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
2006

ChIP-on-beads: Flow-cytometric evaluation of chromatin immunoprecipitation

Székvölgyi, L., Bálint, B. L., Imre, L., Goda, K., Szabó, M., Nagy, L. & Szabó, G., Oct 1 2006, In : Cytometry Part A. 69, 10, p. 1086-1091 6 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Non-DNA binding, dominant-negative, human PPARγ mutations cause lipodystrophic insulin resistance

Agostini, M., Schoenmakers, E., Mitchell, C., Szatmari, I., Savage, D., Smith, A., Rajanayagam, O., Semple, R., Luan, J., Bath, L., Zalin, A., Labib, M., Kumar, S., Simpson, H., Blom, D., Marais, D., Schwabe, J., Barroso, I., Trembath, R., Wareham, N. & 4 others, Nagy, L., Gurnell, M., O'Rahilly, S. & Chatterjee, K., Oct 2006, In : Cell Metabolism. 4, 4, p. 303-311 9 p.

Research output: Contribution to journalArticle

129 Citations (Scopus)
136 Citations (Scopus)

PPARγ controls CD1d expression by turning on retinoic acid synthesis in developing human dendritic cells

Szatmari, I., Pap, A., Rühl, R., Ma, J. X., Illarionov, P. A., Besra, G. S., Rajnavolgyi, E., Dezso, B. & Nagy, L., 2006, In : Journal of Experimental Medicine. 203, 10, p. 2351-2362 12 p.

Research output: Contribution to journalArticle

147 Citations (Scopus)

SLAM/SLAM interactions inhibit CD40-induced production of inflammatory cytokines in monocyte-derived dendritic cells

Réthi, B., Gogolák, P., Szatmari, I., Veres, Á., Erdõs, E., Nagy, L., Rajnavölgyi, É., Terhorst, C. & Lányi, Á., Apr 1 2006, In : Blood. 107, 7, p. 2821-2829 9 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)

Twenty years of nuclear receptors: Conference on nuclear receptors: From chromatin to disease

Nagy, L., Schüle, R. & Gronemeyer, H., Jun 1 2006, In : EMBO Reports. 7, 6, p. 579-584 6 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2007
90 Citations (Scopus)

Monoclonal antibody proteomics: Discovery and prevalidation of chronic obstructive pulmonary disease biomarkers in a single step

Csanky, E., Olivova, P., Rajnavolgyi, E., Hempel, W., Tardieu, N., Katalin, E. T., Jullien, A., Malderez-Bloes, C., Kuras, M., Duval, M. X., Nagy, L., Scholtz, B., Hancock, W., Karger, B., Guttman, A. & Takacs, L., Dec 2007, In : ELECTROPHORESIS. 28, 23, p. 4401-4406 6 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

PPARγ regulates the function of human dendritic cells primarily by altering lipid metabolism

Szatmari, I., Töröcsik, D., Agostini, M., Nagy, T., Gurnell, M., Barta, E., Chatterjee, K. & Nagy, L., Nov 1 2007, In : Blood. 110, 9, p. 3271-3280 10 p.

Research output: Contribution to journalArticle

84 Citations (Scopus)

Ribonucleoprotein-masked nicks at 50-kbp intervals in the eukaryotic genomic DNA

Székvölgyi, L., Rákosy, Z., Bálint, B. L., Kókai, E., Imre, L., Vereb, G., Bacsó, Z., Goda, K., Varga, S., Balázs, M., Dombrádi, V., Nagy, L. & Szabó, G., Sep 18 2007, In : Proceedings of the National Academy of Sciences of the United States of America. 104, 38, p. 14964-14969 6 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)
2008

Endocannabinoids enhance lipid synthesis and apoptosis of human sebocytes via cannabinoid receptor-2-mediated signaling

Dobrosi, N., Tóth, B. I., Nagy, G., Dózsa, A., Géczy, T., Nagy, L., Zouboulis, C. C., Paus, R., Kovács, L. & Bíró, T., Oct 2008, In : FASEB Journal. 22, 10, p. 3685-3695 11 p.

Research output: Contribution to journalArticle

88 Citations (Scopus)

Functional ABCG1 expression induces apoptosis in macrophages and other cell types

Seres, L., Cserepes, J., Elkind, N. B., Törocsik, D., Nagy, L., Sarkadi, B. & Homolya, L., Oct 1 2008, In : Biochimica et Biophysica Acta - Biomembranes. 1778, 10, p. 2378-2387 10 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Structural basis for the activation of PPARγ by oxidized fatty acids

Itoh, T., Fairall, L., Amin, K., Inaba, Y., Szanto, A., Balint, B. L., Nagy, L., Yamamoto, K. & Schwabe, J. W. R., Sep 1 2008, In : Nature Structural and Molecular Biology. 15, 9, p. 924-931 8 p.

Research output: Contribution to journalArticle

279 Citations (Scopus)
2009

1,25-Dihydroxyvitamin D3 Is an autonomous regulator of the transcriptional changes leading to a tolerogenic dendritic cell phenotype

Széles, L., Keresztes, G., Töröcsik, D., Balajthy, Z., Krenács, L., Póliska, S., Steinmeyer, A., Zuegel, U., Pruenster, M., Rot, A. & Nagy, L., Feb 15 2009, In : Journal of Immunology. 182, 4, p. 2074-2083 10 p.

Research output: Contribution to journalArticle

141 Citations (Scopus)

Mycobacterium bovis bacillus Calmette-Guérin infection induces TLR2-dependent peroxisome proliferator-activated receptor γ expression and activation: Functions in inflammation, lipid metabolism, and pathogenesis

Almeida, P. E., Silva, A. R., Maya-Monteiro, C. M., Töröcsik, D., D'Ávila, H., Dezsö, B., Magalhães, K. G., Castro-Faria-Neto, H. C., Nagy, L. & Bozza, P. T., Jul 15 2009, In : Journal of Immunology. 183, 2, p. 1337-1345 9 p.

Research output: Contribution to journalArticle

100 Citations (Scopus)

Transient receptor potential vanilloid-1 signaling as a regulator of human sebocyte biology

Tóth, B. I., Géczy, T., Griger, Z., Dózsa, A., Seltmann, H., Kovács, L., Nagy, L., Zouboulis, C. C., Paus, R. & Bíró, T., Feb 1 2009, In : Journal of Investigative Dermatology. 129, 2, p. 329-339 11 p.

Research output: Contribution to journalArticle

57 Citations (Scopus)
2010

Activation of liver X receptor sensitizes human dendritic cells to inflammatory stimuli

Töröcsik, D., Baráth, M., Benko, S., Széles, L., Dezso, B., Póliska, S., Hegyi, Z., Homolya, L., Szatmári, I., Lányi, Á. & Nagy, L., May 15 2010, In : Journal of Immunology. 184, 10, p. 5456-5465 10 p.

Research output: Contribution to journalArticle

47 Citations (Scopus)