• 14989 Citations
  • 50 h-Index
1991 …2020

Research output per year

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Research Output

2010

Magyar szkizofrénia-biobank a szkizofréniakutatás és a személyre szabott orvoslás szolgálatában

Translated title of the contribution: SCHIZOBANK - The Hungarian national schizophrenia biobank and its role in schizophrenia researchInczédy-Farkas, G., Benkovits, J., Balogh, N., Álmos, P., Scholtz, B., Zahuczky, G., Török, Z., Nagy, K., Réthelyi, J., Makkos, Z., Kassai-Farkas, Á., Igerházy, A., Tuzko, J., Janka, Z., Bitter, I., Németh, G., Nagy, L. & Molnár, M. J., Aug 1 2010, In : Orvosi hetilap. 151, 35, p. 1403-1408 6 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
64 Citations (Scopus)

Research resource: Transcriptome profiling of genes regulated by RXR and its permissive and nonpermissive partners in differentiating monocyte-derived dendritic cells

Széles, L., Póliska, S., Nagy, G., Szatmari, I., Szanto, A., Pap, A., Lindstedt, M., Santegoets, S. J. A. M., Rühl, R., Dezsö, B. & Nagy, L., Nov 1 2010, In : Molecular Endocrinology. 24, 11, p. 2218-2231 14 p.

Research output: Contribution to journalArticle

51 Citations (Scopus)

STAT6 transcription factor is a facilitator of the nuclear receptor PPARγ-regulated gene expression in macrophages and dendritic cells

Szanto, A., Balint, B. L., Nagy, Z. S., Barta, E., Dezso, B., Pap, A., Szeles, L., Poliska, S., Oros, M., Evans, R. M., Barak, Y., Schwabe, J. & Nagy, L., Nov 24 2010, In : Immunity. 33, 5, p. 699-712 14 p.

Research output: Contribution to journalArticle

222 Citations (Scopus)
2009

1,25-Dihydroxyvitamin D3 Is an autonomous regulator of the transcriptional changes leading to a tolerogenic dendritic cell phenotype

Széles, L., Keresztes, G., Töröcsik, D., Balajthy, Z., Krenács, L., Póliska, S., Steinmeyer, A., Zuegel, U., Pruenster, M., Rot, A. & Nagy, L., Feb 15 2009, In : Journal of Immunology. 182, 4, p. 2074-2083 10 p.

Research output: Contribution to journalArticle

141 Citations (Scopus)

Mycobacterium bovis bacillus Calmette-Guérin infection induces TLR2-dependent peroxisome proliferator-activated receptor γ expression and activation: Functions in inflammation, lipid metabolism, and pathogenesis

Almeida, P. E., Silva, A. R., Maya-Monteiro, C. M., Töröcsik, D., D'Ávila, H., Dezsö, B., Magalhães, K. G., Castro-Faria-Neto, H. C., Nagy, L. & Bozza, P. T., Jul 15 2009, In : Journal of Immunology. 183, 2, p. 1337-1345 9 p.

Research output: Contribution to journalArticle

100 Citations (Scopus)

Oxysterol signaling links cholesterol metabolism and inflammation via the liver X receptor in macrophages

Töröcsik, D., Szanto, A. & Nagy, L., Jun 1 2009, In : Molecular Aspects of Medicine. 30, 3, p. 134-152 19 p.

Research output: Contribution to journalReview article

57 Citations (Scopus)

Transient receptor potential vanilloid-1 signaling as a regulator of human sebocyte biology

Tóth, B. I., Géczy, T., Griger, Z., Dózsa, A., Seltmann, H., Kovács, L., Nagy, L., Zouboulis, C. C., Paus, R. & Bíró, T., Feb 1 2009, In : Journal of Investigative Dermatology. 129, 2, p. 329-339 11 p.

Research output: Contribution to journalArticle

57 Citations (Scopus)
2008

Endocannabinoids enhance lipid synthesis and apoptosis of human sebocytes via cannabinoid receptor-2-mediated signaling

Dobrosi, N., Tóth, B. I., Nagy, G., Dózsa, A., Géczy, T., Nagy, L., Zouboulis, C. C., Paus, R., Kovács, L. & Bíró, T., Oct 2008, In : FASEB Journal. 22, 10, p. 3685-3695 11 p.

Research output: Contribution to journalArticle

88 Citations (Scopus)

Functional ABCG1 expression induces apoptosis in macrophages and other cell types

Seres, L., Cserepes, J., Elkind, N. B., Törocsik, D., Nagy, L., Sarkadi, B. & Homolya, L., Oct 1 2008, In : Biochimica et Biophysica Acta - Biomembranes. 1778, 10, p. 2378-2387 10 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)
47 Citations (Scopus)

Nuclear receptor signalling in dendritic cells connects lipids, the genome and immune function

Szatmari, I. & Nagy, L., Sep 17 2008, In : EMBO Journal. 27, 18, p. 2353-2362 10 p.

Research output: Contribution to journalReview article

58 Citations (Scopus)

Of Vitruvian mice and men

Nagy, L. & Tontonoz, P., Jan 9 2008, In : FEBS letters. 582, 1, 1 p.

Research output: Contribution to journalEditorial

Potential therapeutic use of PPARγ-programed human monocyte-derived dendritic cells in cancer vaccination therapy

Gyöngyösi, A. & Nagy, L., Nov 18 2008, In : PPAR Research. 473804.

Research output: Contribution to journalReview article

Structural basis for the activation of PPARγ by oxidized fatty acids

Itoh, T., Fairall, L., Amin, K., Inaba, Y., Szanto, A., Balint, B. L., Nagy, L., Yamamoto, K. & Schwabe, J. W. R., Sep 1 2008, In : Nature Structural and Molecular Biology. 15, 9, p. 924-931 8 p.

Research output: Contribution to journalArticle

279 Citations (Scopus)

The many faces of PPARγ: Anti-inflammatory by any means?

Szanto, A. & Nagy, L., Nov 6 2008, In : Immunobiology. 213, 9-10, p. 789-803 15 p.

Research output: Contribution to journalReview article

111 Citations (Scopus)
2007
90 Citations (Scopus)

Monoclonal antibody proteomics: Discovery and prevalidation of chronic obstructive pulmonary disease biomarkers in a single step

Csanky, E., Olivova, P., Rajnavolgyi, E., Hempel, W., Tardieu, N., Katalin, E. T., Jullien, A., Malderez-Bloes, C., Kuras, M., Duval, M. X., Nagy, L., Scholtz, B., Hancock, W., Karger, B., Guttman, A. & Takacs, L., Dec 2007, In : ELECTROPHORESIS. 28, 23, p. 4401-4406 6 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

PPARγ in immunity and inflammation: cell types and diseases

Széles, L., Töröcsik, D. & Nagy, L., Aug 1 2007, In : Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1771, 8, p. 1014-1030 17 p.

Research output: Contribution to journalReview article

117 Citations (Scopus)

PPARγ regulates the function of human dendritic cells primarily by altering lipid metabolism

Szatmari, I., Töröcsik, D., Agostini, M., Nagy, T., Gurnell, M., Barta, E., Chatterjee, K. & Nagy, L., Nov 1 2007, In : Blood. 110, 9, p. 3271-3280 10 p.

Research output: Contribution to journalArticle

84 Citations (Scopus)

Ribonucleoprotein-masked nicks at 50-kbp intervals in the eukaryotic genomic DNA

Székvölgyi, L., Rákosy, Z., Bálint, B. L., Kókai, E., Imre, L., Vereb, G., Bacsó, Z., Goda, K., Varga, S., Balázs, M., Dombrádi, V., Nagy, L. & Szabó, G., Sep 18 2007, In : Proceedings of the National Academy of Sciences of the United States of America. 104, 38, p. 14964-14969 6 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)
2006

ChIP-on-beads: Flow-cytometric evaluation of chromatin immunoprecipitation

Székvölgyi, L., Bálint, B. L., Imre, L., Goda, K., Szabó, M., Nagy, L. & Szabó, G., Oct 1 2006, In : Cytometry Part A. 69, 10, p. 1086-1091 6 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Non-DNA binding, dominant-negative, human PPARγ mutations cause lipodystrophic insulin resistance

Agostini, M., Schoenmakers, E., Mitchell, C., Szatmari, I., Savage, D., Smith, A., Rajanayagam, O., Semple, R., Luan, J., Bath, L., Zalin, A., Labib, M., Kumar, S., Simpson, H., Blom, D., Marais, D., Schwabe, J., Barroso, I., Trembath, R., Wareham, N. & 4 others, Nagy, L., Gurnell, M., O'Rahilly, S. & Chatterjee, K., Oct 2006, In : Cell Metabolism. 4, 4, p. 303-311 9 p.

Research output: Contribution to journalArticle

129 Citations (Scopus)
136 Citations (Scopus)

PPARγ, a lipid-activated transcription factor as a regulator of dendritic cell function

Szatmari, I., Rajnavolgyi, E. & Nagy, L., Nov 2006, Neuroendocrine and Immune Crosstalk. Blackwell Publishing Inc., p. 207-218 12 p. (Annals of the New York Academy of Sciences; vol. 1088).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

47 Citations (Scopus)

PPARγ controls CD1d expression by turning on retinoic acid synthesis in developing human dendritic cells

Szatmari, I., Pap, A., Rühl, R., Ma, J. X., Illarionov, P. A., Besra, G. S., Rajnavolgyi, E., Dezso, B. & Nagy, L., 2006, In : Journal of Experimental Medicine. 203, 10, p. 2351-2362 12 p.

Research output: Contribution to journalArticle

147 Citations (Scopus)

Selective modulators of PPAR activity as new therapeutic tools in metabolic diseases

Balint, B. L. & Nagy, L., Mar 2006, In : Endocrine, Metabolic and Immune Disorders - Drug Targets. 6, 1, p. 33-43 11 p.

Research output: Contribution to journalReview article

56 Citations (Scopus)

SLAM/SLAM interactions inhibit CD40-induced production of inflammatory cytokines in monocyte-derived dendritic cells

Réthi, B., Gogolák, P., Szatmari, I., Veres, Á., Erdõs, E., Nagy, L., Rajnavölgyi, É., Terhorst, C. & Lányi, Á., Apr 1 2006, In : Blood. 107, 7, p. 2821-2829 9 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)

Twenty years of nuclear receptors: Conference on nuclear receptors: From chromatin to disease

Nagy, L., Schüle, R. & Gronemeyer, H., Jun 1 2006, In : EMBO Reports. 7, 6, p. 579-584 6 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2005

Accelerated recovery of 5-fluorouracil-damaged bone marrow after rosiglitazone treatment

Djazayeri, K., Szilvássy, Z., Peitl, B., Németh, J., Nagy, L., Kiss, A., Szabó, B. & Benko, I., Oct 17 2005, In : European Journal of Pharmacology. 522, 1-3, p. 122-129 8 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Arginine methylation provides epigenetic transcription memory for retinoid-induced differentiation in myeloid cells

Balint, B. L., Szanto, A., Madi, A., Bauer, U. M., Gabor, P., Benko, S., Puskás, L. G., Davies, P. J. A. & Nagy, L., Jul 2005, In : Molecular and cellular biology. 25, 13, p. 5648-5663 16 p.

Research output: Contribution to journalArticle

45 Citations (Scopus)

Atherosclerosis and lipid peroxidation

Nagy, L. & Spiteller, G., Nov 1 2005, In : Molecular Nutrition and Food Research. 49, 11, p. 989-991 3 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
17 Citations (Scopus)

Genome-wide localization of histone 4 arginine 3 methylation in a differentiation primed myeloid leukemia cell line

Balint, B. L., Gabor, P. & Nagy, L., Aug 19 2005, In : Immunobiology. 210, 2-4, p. 141-152 12 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
71 Citations (Scopus)
43 Citations (Scopus)

Roles for lipid-activated transcription factors in atherosclerosis

Nagy, L. & Szanto, A., Nov 1 2005, In : Molecular Nutrition and Food Research. 49, 11, p. 1072-1074 3 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Spotlight on...Laszlo Nagy: Editor of FEBS Letters since 2005

Nagy, L., Nov 7 2005, In : FEBS letters. 579, 27, 1 p.

Research output: Contribution to journalEditorial

2004
118 Citations (Scopus)

Mechanism of the nuclear receptor molecular switch

Nagy, L. & Schwabe, J. W. R., Jun 1 2004, In : Trends in Biochemical Sciences. 29, 6, p. 317-324 8 p.

Research output: Contribution to journalReview article

266 Citations (Scopus)

Review retinoid x receptors: X-ploring their (patho)physiological functions

Szanto, A., Narkar, V., Shen, Q., Uray, I. P., Davies, P. J. A. & Nagy, L., Jan 1 2004, In : Cell Death and Differentiation. 11, p. S126-S143

Research output: Contribution to journalReview article

184 Citations (Scopus)

Transcriptional regulation of human CYP27 integrates retinoid, peroxisome proliferator-activated receptor, and liver X receptor signaling in macrophages

Szanto, A., Benko, S., Szatmari, I., Balint, B. L., Furtos, I., Rühl, R., Molnar, S., Csiba, L., Garuti, R., Calandra, S., Larsson, H., Diczfalusy, U. & Nagy, L., Sep 2004, In : Molecular and cellular biology. 24, 18, p. 8154-8166 13 p.

Research output: Contribution to journalArticle

97 Citations (Scopus)
2003

Molecular Determinants of the Balance between Co-repressor and Co-activator Recruitment to the Retinoic Acid Receptor

Benko, S., Love, J. D., Beládi, M., Schwabe, J. W. R. & Nagy, L., Oct 31 2003, In : Journal of Biological Chemistry. 278, 44, p. 43797-43806 10 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

The retinoid X receptor and its ligands: Versatile regulators of metabolic function, cell differentiation and cell death

Ahuja, H. S., Szanto, A., Nagy, L. & Davies, P. J. A., Jan 1 2003, In : Journal of Biological Regulators and Homeostatic Agents. 17, 1, p. 29-45 17 p.

Research output: Contribution to journalReview article

104 Citations (Scopus)
2002

The structural basis for the specificity of retinoid-X receptor-selective agonists: New insights into the role of helix H12

Love, J. D., Gooch, J. T., Benko, S., Li, C., Nagy, L., Krishna K Chatterjee, V., Evans, R. M. & Schwabe, J. W. R., Mar 29 2002, In : Journal of Biological Chemistry. 277, 13, p. 11385-11391 7 p.

Research output: Contribution to journalArticle

62 Citations (Scopus)
2001

A PPARγ-LXR-ABCA1 pathway in macrophages is involved in cholesterol efflux and atherogenesis

Chawla, A., Boisvert, W. A., Lee, C. H., Laffitte, B. A., Barak, Y., Joseph, S. B., Liao, D., Nagy, L., Edwards, P. A., Curtiss, L. K., Evans, R. M. & Tontonoz, P., Jan 1 2001, In : Molecular Cell. 7, 1, p. 161-171 11 p.

Research output: Contribution to journalArticle

1037 Citations (Scopus)

Differential effects of rexinoids and thiazolidinediones on metabolic gene expression in diabetic rodents

Ahuja, H. S., Liu, S., Crombie, D. L., Boehm, M., Leibowitz, M. D., Heyman, R. A., Depre, C., Nagy, L., Tontonoz, P. & Davies, P. J. A., Jan 1 2001, In : Molecular pharmacology. 59, 4, p. 765-773 9 p.

Research output: Contribution to journalArticle

101 Citations (Scopus)

PPAR-γ dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation

Chawla, A., Barak, Y., Nagy, L., Liao, D., Tontonoz, P. & Evans, R. M., Feb 5 2001, In : Nature medicine. 7, 1, p. 48-52 5 p.

Research output: Contribution to journalArticle

904 Citations (Scopus)
2000

Apoptosis-linked in vivo regulation of the tissue transglutaminase gene promoter

Szegezdi, É., Szondy, Z., Nagy, L., Nemes, Z., Friis, R. R., Davies, P. J. A. & Fésüs, L., Dec 1 2000, In : Cell Death and Differentiation. 7, 12, p. 1225-1233 9 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)