• 14989 Citations
  • 50 h-Index
1991 …2020

Research output per year

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Research Output

2015

Oral health-related quality of life after prosthetic rehabilitation: A longitudinal study with the OHIP questionnaire

Jenei, Á., Sándor, J., HegedUs, C., Bágyi, K., Nagy, L., Kiss, C., Szabó, G. & Márton, I. J., Jul 10 2015, In : Health and Quality of Life Outcomes. 13, 1, 99.

Research output: Contribution to journalArticle

7 Citations (Scopus)

PRMT1 and PRMT8 regulate retinoic acid-dependent neuronal differentiation with implications to neuropathology

Simandi, Z., Czipa, E., Horvath, A., Koszeghy, A., Bordas, C., Põliska, S., Juhász, I., Imre, L., Szabõ, G., Dezso, B., Barta, E., Sauer, S., Karolyi, K., Kovacs, I., Hutõczki, G., Bognár, L., Klekner, Á., Szucs, P., Bálint, B. L. & Nagy, L., Mar 1 2015, In : Stem Cells. 33, 3, p. 726-741 16 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

The novel cardiac myosin activator omecamtiv mecarbil increases the calcium sensitivity of force production in isolated cardiomyocytes and skeletal muscle fibres of the rat

Nagy, L., Kovács, Bõdi, B., Pásztor, E. T., Fülöp, G., Tõth, A., Édes, I. & Papp, Z., Sep 1 2015, In : British journal of pharmacology. 172, 18, p. 4506-4518 13 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)
2014

Causes and Pathophysiology of Heart Failure with Preserved Ejection Fraction

Kovács, Á., Papp, Z. & Nagy, L., Jul 2014, In : Heart Failure Clinics. 10, 3, p. 389-398 10 p.

Research output: Contribution to journalReview article

16 Citations (Scopus)

Highly efficient differentiation of embryonic stem cells into adipocytes by ascorbic acid

Cuaranta-Monroy, I., Simandi, Z., Kolostyak, Z., Doan-Xuan, Q. M., Poliska, S., Horvath, A., Nagy, G., Bacso, Z. & Nagy, L., Jul 2014, In : Stem Cell Research. 13, 1, p. 88-97 10 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Inotropes and inodilators for acute heart failure: Sarcomere active drugs in focus

Nagy, L., Pollesello, P. & Papp, Z., Sep 1 2014, In : Journal of cardiovascular pharmacology. 64, 3, p. 199-208 10 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Ligand binding shifts highly mobile retinoid X receptor to the chromatin-bound state in a coactivator-dependent manner, as revealed by single-cell imaging

Brazda, P., Krieger, J., Daniel, B., Jonas, D., Szekeres, T., Langowski, J., Tóth, K., Nagy, L. & Vámosi, G., Apr 2014, In : Molecular and cellular biology. 34, 7, p. 1234-1245 12 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Mapping the genomic binding sites of the activated retinoid X receptor in murine bone marrow-derived macrophages using chromatin immunoprecipitation sequencing

Daniel, B., Balint, B. L., Nagy, Z. S. & Nagy, L., Jan 1 2014, In : Methods in Molecular Biology. 1204, p. 15-24 10 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Measuring expression levels of small regulatory RNA molecules from body fluids and formalin-fixed, paraffin-embedded samples

Gyongyosi, A., Docs, O., Czimmerer, Z., Orosz, L., Horvath, A., Török, O., Mehes, G., Nagy, L. & Balint, B. L., 2014, RNA Mapping: Methods and Protocols. Humana Press Inc., p. 105-119 15 p. (Methods in Molecular Biology; vol. 1182).

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Citations (Scopus)

Myofilament carbonylation modulates contractility in human cardiomyocytes

Balogh, Á., Tot́h, A., Pásztorńe, E. T., Nagy, L., Kov́acs, Á., Kalaśz, J., Contreras, G. A., Édes, I. & Papp, Z., 2014, In : Experimental and Clinical Cardiology. 20, 1, p. 2026-2035 10 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

PPARγ activation but not PPARγ haplodeficiency affects proangiogenic potential of endothelial cells and bone marrow-derived progenitors

Kotlinowski, J., Grochot-Przeczek, A., Taha, H., Kozakowska, M., Pilecki, B., Skrzypek, K., Bartelik, A., Derlacz, R., Horrevoets, A. J. G., Pap, A., Nagy, L., Dulak, J. & Jozkowicz, A., Nov 1 2014, In : Cardiovascular diabetology. 13, 1, 150.

Research output: Contribution to journalArticle

13 Citations (Scopus)

PPARγ-mediated and arachidonic acid-dependent signaling is involved in differentiation and lipid production of human sebocytes

Dozsa, A., Dezso, B., Toth, B. I., Bacsi, A., Poliska, S., Camera, E., Picardo, M., Zouboulis, C. C., Bíró, T., Schmitz, G., Liebisch, G., Rühl, R., Remenyik, E. & Nagy, L., Apr 2014, In : Journal of Investigative Dermatology. 134, 4, p. 910-920 11 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)

The active enhancer network operated by liganded RXR supports angiogenic activity in macrophages

Daniel, B., Nagy, G., Hah, N., Horvath, A., Czimmerer, Z., Poliska, S., Gyuris, T., Keirsse, J., Gysemans, C., Van Ginderachter, J. A., Balint, B. L., Evans, R. M., Barta, E. & Nagy, L., Jul 15 2014, In : Genes and Development. 28, 14, p. 1562-1577 16 p.

Research output: Contribution to journalArticle

52 Citations (Scopus)

The intriguing complexities of mammalian gene regulation: How to link enhancers to regulated genes. Are we there yet?

Daniel, B., Nagy, G. & Nagy, L., Aug 1 2014, In : FEBS letters. 588, 15, p. 2379-2391 13 p.

Research output: Contribution to journalReview article

9 Citations (Scopus)
2013

A funkcionális genomikai eszköztár szerepe az onkológiai kutatásokban

Translated title of the contribution: The place of functional genomics in oncological researchBálint, B. L. & László, N., 2013, In : Magyar onkologia. 57, 1, p. 21-25 5 p.

Research output: Contribution to journalArticle

A novel method to predict regulatory regions based on histone mark landscapes in macrophages

Nagy, G., Dániel, B., Jónás, D., Nagy, L. & Barta, E., Nov 1 2013, In : Immunobiology. 218, 11, p. 1416-1427 12 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

A Versatile Method to Design Stem-Loop Primer-Based Quantitative PCR Assays for Detecting Small Regulatory RNA Molecules

Czimmerer, Z., Hulvely, J., Simandi, Z., Varallyay, E., Havelda, Z., Szabo, E., Varga, A., Dezso, B., Balogh, M., Horvath, A., Domokos, B., Torok, Z., Nagy, L. & Balint, B. L., Jan 31 2013, In : PloS one. 8, 1, e55168.

Research output: Contribution to journalArticle

57 Citations (Scopus)

Correction: Genome wide mapping reveals PDE4B as an IL-2 induced STAT5 target gene in activated human PBMCs and lymphoid cancer cells (PLoS ONE)

Nagy, Z. S., Ross, J. A., Rodriguez, G., Balint, B. L., Szeles, L., Nagy, L. & Kirken, R. A., Feb 27 2013, In : PloS one. 8, 2

Research output: Contribution to journalComment/debate

Genome Wide Mapping Reveals PDE4B as an IL-2 Induced STAT5 Target Gene in Activated Human PBMCs and Lymphoid Cancer Cells

Nagy, Z. S., Ross, J. A., Rodriguez, G., Balint, B. L., Szeles, L., Nagy, L. & Kirken, R. A., Feb 25 2013, In : PloS one. 8, 2, e57326.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Hmgb1 can facilitate activation of the matrilin-1 gene promoter by Sox9 and L-Sox5/Sox6 in early steps of chondrogenesis

Szénási, T., Kénesi, E., Nagy, A., Molnár, A., Bálint, B. L., Zvara, G., Csabai, Z., Deák, F., Boros Oláh, B., Mátés, L., Nagy, L., Puskás, L. G. & Kiss, I., Oct 1 2013, In : Biochimica et Biophysica Acta - Gene Regulatory Mechanisms. 1829, 10, p. 1075-1091 17 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Nuclear receptor mediated mechanisms of macrophage cholesterol metabolism

Nagy, Z. S., Czimmerer, Z. & Nagy, L., Apr 10 2013, In : Molecular and Cellular Endocrinology. 368, 1-2, p. 85-98 14 p.

Research output: Contribution to journalReview article

13 Citations (Scopus)

Nuclear receptors as regulators of stem cell and cancer stem cell metabolism

Simandi, Z., Cuaranta-Monroy, I. & Nagy, L., Dec 2013, In : Seminars in Cell and Developmental Biology. 24, 10-12, p. 716-723 8 p.

Research output: Contribution to journalReview article

8 Citations (Scopus)

Peripheral blood derived gene panels predict response to infliximab in rheumatoid arthritis and Crohn's disease

Mesko, B., Poliska, S., Váncsa, A., Szekanecz, Z., Palatka, K., Hollo, Z., Horvath, A., Steiner, L., Zahuczky, G., Podani, J. & Nagy, L., Jun 28 2013, In : Genome Medicine. 5, 6, 59.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Pharmacogenetics and pharmacogenomics in rheumatology

Szekanecz, Z., Meskó, B., Poliska, S., Váncsa, A., Szamosi, S., Végh, E., Simkovics, E., Laki, J., Kurkó, J., Besenyei, T., Mikecz, K., Glant, T. T. & Nagy, L., Jul 1 2013, In : Immunologic Research. 56, 2-3, p. 325-333 9 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

PPARγ needs a helping hand to make fat

Cuaranta-Monroy, I. & Nagy, L., Dec 1 2013, In : Cell Death and Differentiation. 20, 12, p. 1599-1600 2 p.

Research output: Contribution to journalEditorial

Pro-inflammatory cytokines negatively regulate PPARγ mediated gene expression in both human and murine macrophages via multiple mechanisms

Nagy, Z. S., Czimmerer, Z., Szanto, A. & Nagy, L., Nov 1 2013, In : Immunobiology. 218, 11, p. 1336-1344 9 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

RDH10, RALDH2, and CRABP2 are required components of PPAR γ-directed ATRA synthesis and signaling in human dendritic cells

Gyöngyösi, A., Szatmari, I., Pap, A., Dezso, B., Pos, Z., Széles, L., Varga, T. & Nagy, L., Sep 2013, In : Journal of Lipid Research. 54, 9, p. 2458-2474 17 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Reprogramming of lysosomal gene expression by interleukin-4 and Stat6

Brignull, L. M., Czimmerer, Z., Saidi, H., Daniel, B., Villela, I., Bartlett, N. W., Johnston, S. L., Meira, L. B., Nagy, L. & Nohturfft, A., Dec 5 2013, In : BMC genomics. 14, 1, 853.

Research output: Contribution to journalArticle

12 Citations (Scopus)

The role of lipid-activated nuclear receptors in shaping macrophage and dendritic cell function: From physiology to pathology

Kiss, M., Czimmerer, Z. & Nagy, L., Aug 2013, In : Journal of Allergy and Clinical Immunology. 132, 2, p. 264-286 23 p.

Research output: Contribution to journalReview article

82 Citations (Scopus)

Tissue LyC6- macrophages are generated in the absence of circulating LyC6- monocytes and Nur77 in a model of muscle regeneration

Varga, T., Mounier, R., Gogolak, P., Poliska, S., Chazaud, B. & Nagy, L., Dec 1 2013, In : Journal of Immunology. 191, 11, p. 5695-5701 7 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)
2012
12 Citations (Scopus)

Carboxypeptidase-M is regulated by lipids and CSFs in macrophages and dendritic cells and expressed selectively in tissue granulomas and foam cells

Tsakiris, I., Torocsik, D., Gyongyosi, A., Dozsa, A., Szatmari, I., Szanto, A., Soos, G., Nemes, Z., Igali, L., Marton, I., Takats, Z., Nagy, L. & Dezso, B., Mar 2012, In : Laboratory Investigation. 92, 3, p. 345-361 17 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Ethanol increases phosphate-mediated mineralization and osteoblastic transformation of vascular smooth muscle cells

Oros, M., Zavaczki, E., Vadasz, C., Jeney, V., Tosaki, A., Lekli, I., Balla, G., Nagy, L. & Balla, J., Sep 1 2012, In : Journal of Cellular and Molecular Medicine. 16, 9, p. 2219-2226 8 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Identification of novel markers of alternative activation and potential endogenous PPARγ ligand production mechanisms in human IL-4 stimulated differentiating macrophages

Czimmerer, Z., Varga, T., Poliska, S., Nemet, I., Szanto, A. & Nagy, L., Dec 1 2012, In : Immunobiology. 217, 12, p. 1301-1314 14 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)
123 Citations (Scopus)

Peripheral blood gene expression and IgG glycosylation profiles as markers of tocilizumab treatment in rheumatoid arthritis

Mesko, B., Poliska, S., Szamosi, S., Szekanecz, Z., Podani, J., Varadi, C., Guttman, A. & Nagy, L., May 1 2012, In : Journal of Rheumatology. 39, 5, p. 916-928 13 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

The triad of success in personalised medicine: Pharmacogenomics, biotechnology and regulatory issues from a Central European perspective

Mesko, B., Zahuczky, G. & Nagy, L., Sep 15 2012, In : New Biotechnology. 29, 6, p. 741-750 10 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Would eating carrots protect your liver? A new role involving NKT cells for retinoic acid in hepatitis

Nagy, L., Jul 1 2012, In : European journal of immunology. 42, 7, p. 1677-1680 4 p.

Research output: Contribution to journalComment/debate

7 Citations (Scopus)
2011

Chronic obstructive pulmonary disease-specific gene expression signatures of alveolar macrophages as well as peripheral blood monocytes overlap and correlate with lung function

Poliska, S., Csanky, E., Szanto, A., Szatmari, I., Mesko, B., Szeles, L., Dezso, B., Scholtz, B., Podani, J., Kilty, I., Takacs, L. & Nagy, L., May 1 2011, In : Respiration. 81, 6, p. 499-510 12 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Gene expression profiles in peripheral blood for the diagnosis of autoimmune diseases

Mesko, B., Poliska, S. & Nagy, L., Apr 1 2011, In : Trends in Molecular Medicine. 17, 4, p. 223-233 11 p.

Research output: Contribution to journalReview article

30 Citations (Scopus)

Live-cell fluorescence correlation spectroscopy dissects the role of coregulator exchange and chromatin binding in retinoic acid receptor mobility

Brazda, P., Szekeres, T., Bravics, B., Tóth, K., Vámosi, G. & Nagy, L., Nov 1 2011, In : Journal of cell science. 124, 21, p. 3631-3642 12 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)

Peroxisome proliferator-activated receptor γ-regulated cathepsin D is required for lipid antigen presentation by dendritic cells

Nakken, B., Varga, T., Szatmari, I., Szeles, L., Gyongyosi, A., Illarionov, P. A., Dezso, B., Gogolak, P., Rajnavolgyi, E. & Nagy, L., Jul 1 2011, In : Journal of Immunology. 187, 1, p. 240-247 8 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

PPARs are a unique set of fatty acid regulated transcription factors controlling both lipid metabolism and inflammation

Varga, T., Czimmerer, Z. & Nagy, L., Aug 1 2011, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1812, 8, p. 1007-1022 16 p.

Research output: Contribution to journalReview article

373 Citations (Scopus)

Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery

Oberoi, J., Fairall, L., Watson, P. J., Yang, J. C., Czimmerer, Z., Kampmann, T., Goult, B. T., Greenwood, J. A., Gooch, J. T., Kallenberger, B. C., Nagy, L., Neuhaus, D. & Schwabe, J. W. R., Feb 1 2011, In : Nature Structural and Molecular Biology. 18, 2, p. 177-185 9 p.

Research output: Contribution to journalArticle

87 Citations (Scopus)
2010

Activation of liver X receptor sensitizes human dendritic cells to inflammatory stimuli

Töröcsik, D., Baráth, M., Benko, S., Széles, L., Dezso, B., Póliska, S., Hegyi, Z., Homolya, L., Szatmári, I., Lányi, Á. & Nagy, L., May 15 2010, In : Journal of Immunology. 184, 10, p. 5456-5465 10 p.

Research output: Contribution to journalArticle

47 Citations (Scopus)

Activation of retinoic acid receptor signaling coordinates lineage commitment of spontaneously differentiating mouse embryonic stem cells in embryoid bodies

Simandi, Z., Balint, B. L., Poliska, S., Ruhl, R. & Nagy, L., Jul 1 2010, In : FEBS letters. 584, 14, p. 3123-3130 8 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Analyses of association between PPAR gamma and EPHX1 polymorphisms and susceptibility to COPD in a Hungarian cohort, a case-control study

Penyige, A., Poliska, S., Csanky, E., Scholtz, B., Dezso, B., Schmelczer, I., Kilty, I., Takacs, L. & Nagy, L., Nov 4 2010, In : BMC Medical Genetics. 11, 1, 152.

Research output: Contribution to journalArticle

21 Citations (Scopus)
21 Citations (Scopus)