• 834 Citations
  • 18 h-Index
1992 …2019

Research output per year

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Research Output

  • 834 Citations
  • 18 h-Index
  • 60 Article
  • 1 Comment/debate
  • 1 Letter
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Article
2019

(±)-trans-Dihydronarciclasine and (±)-trans-dihydrolycoricidine analogues modified in their ring A: Evaluation of their anticancer activity and a SAR study

Varró, G., Pálchuber, P., Pogrányi, B., Simon, A., Hegedûs, L. & Kádas, I., Jul 1 2019, In : European Journal of Medicinal Chemistry. 173, p. 76-89 14 p.

Research output: Contribution to journalArticle

Open Access

Recent achievements in the hydrogenation of nitriles catalyzed by transitional metals

Lévay, K. & Hegedűs, L., Jan 1 2019, In : Current Organic Chemistry. 23, 18, p. 1881-1900 20 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)
2018

Green synthesis and cytotoxic activity of dibenzyl α-hydroxyphosphonates and α-hydroxyphosphonic acids

Rádai, Z., Szeles, P., Kiss, N. Z., Hegedûs, L., Windt, T., Nagy, V. & Keglevich, G., Jan 1 2018, (Accepted/In press) In : Heteroatom Chemistry.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Highly Stereoselective Synthesis of trans -Dihydronarciclasine Analogues

Varró, G., Mattyasovszky, L., Grün, A., Simon, A., Hegedûs, L. & Kádas, I., Feb 1 2018, In : Synthesis (Germany). 50, 3, p. 625-643 19 p., ss-2017-t0559-op.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Poisoning and Reuse of Supported Precious Metal Catalysts in the Hydrogenation of N-Heterocycles Part I: Ruthenium-Catalysed Hydrogenation of 1-Methylpyrrole

Hegedűs, L., Szőke-Molnár, K., Sajó, I. E., Srankó, D. F. & Schay, Z., May 11 2018, (Accepted/In press) In : Catalysis Letters. p. 1-12 12 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Selective heterogeneous catalytic hydrogenation of nitriles to primary amines

Lévay, K. & Hegedûs, L., Nov 20 2018, In : Periodica Polytechnica Chemical Engineering. 62, 4, p. 476-488 13 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Stereoselective synthesis of trans-dihydronarciclasine derivatives containing a 1,4-benzodioxane moiety

Varró, G., Pogrányi, B., Grün, A., Simon, A., Hegedûs, L. & Kádas, I., Dec 1 2018, In : Monatshefte fur Chemie. 149, 12, p. 2265-2285 21 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Synthesis and recovery of pyridine-and piperidine-based camphorsulfonamide organocatalysts used for michael addition reaction

Kisszékelyi, P., Nagy, S., Tóth, B., Zeller, B., Hegedûs, L., Mátravölgyi, B., Grün, A., Németh, T., Huszthy, P. & Kupai, J., Nov 20 2018, In : Periodica Polytechnica Chemical Engineering. 62, 4, p. 489-496 8 p.

Research output: Contribution to journalArticle

Treatments of Lignocellulosic Hydrolysates and Continuous-Flow Hydrogenation of Xylose to Xylitol

Fehér, A., Fehér, C., Rozbach, M., Rácz, G., Fekete, M., Hegedûs, L. & Barta, Z., Mar 1 2018, In : Chemical Engineering and Technology. 41, 3, p. 496-503 8 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2017

The First Enantioselective Total Synthesis of (-)-Trans-Dihydronarciclasine

Varró, G., Hegedûs, L., Simon, A., Balogh, A., Grün, A., Leveles, I., Vértessy, B. & Kádas, I., Jun 23 2017, In : Journal of Natural Products. 80, 6, p. 1909-1917 9 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2016

An efficient stereoselective total synthesis of (±)-trans-dihydronarciclasine

Varró, G., Hegedûs, L., Simon, A. & Kádas, I., Apr 6 2016, In : Tetrahedron Letters. 57, 14

Research output: Contribution to journalArticle

7 Citations (Scopus)

Anomalous products in the halogenation reactions of Vinca alkaloids

Keglevich, A., Hegedûs, L., Péter, L., Gyenese, J., Szántay, C., Dubrovay, Z., Dékány, M., Szigetvári, Á., Martins, A., Molnár, J., Hunyadi, A., Keglevich, P. & Hazai, L., Oct 1 2016, In : Current Organic Chemistry. 20, 24, p. 2639-2646 8 p.

Research output: Contribution to journalArticle

Synthesis and determination of pKa values of new enantiopure pyridino- and piperidino-18-crown-6 ethers

Kupai, J., Kisszékelyi, P., Rojik, E., Dargó, G., Hegedûs, L., Bezzegh, D., Maszler, P., Szabó, L., Németh, T., Balogh, G. T. & Huszthy, P., 2016, In : Arkivoc. 2016, 4, p. 130-151 22 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2015

Asymmetric Michael Addition of Malonates to Enones Catalyzed by an α- D -Glucopyranoside-Based Crown Ether

Bakó, P., Rapi, Z., Grün, A., Nemcsok, T., Hegedus, L. & Keglevich, G., Aug 12 2015, In : Synlett. 26, 13, p. 1847-1851 5 p., st-2015-b0142-l.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Synthesis and application of new, optically active compounds as catalysts and Ligands in Enantioselective reactions

Mátravölgyi, B., Kovács, E., Hegedűs, L., Jászay, Z., Thurner, A., Deák, S., Erdélyi, Z., Pham, T. S., Gönczi, K., Sólyom, S., Tőke, L. & Faigl, F., Jan 1 2015, In : Periodica Polytechnica Chemical Engineering. 59, 1, p. 38-50 13 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
2014

Chiral resolution of racemic cyclopropanecarboxylic acids in supercritical carbon dioxide

Varga, D., Bánsághi, G., Pérez, J. A. M., Miskolczi, S., Hegedus, L., Simándi, B. & Székely, E., Nov 1 2014, In : Chemical Engineering and Technology. 37, 11, p. 1885-1890 6 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2 Citations (Scopus)
2013

Cinchona based squaramide catalysed enantioselective Michael addition of α-nitrophosphonates to aryl acrylates: Enantioselective synthesis of quaternary α-aminophosphonates

Pham, T. S., Gönczi, K., Kardos, G., Süle, K., Hegedus, L., Kállay, M., Kubinyi, M., Szabó, P., Petneházy, I., Toke, L. & Jászay, Z., Dec 31 2013, In : Tetrahedron Asymmetry. 24, 24, p. 1605-1614 10 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)
10 Citations (Scopus)
2011

Hydrogenolysis of N-protected aminooxetanes over palladium: An efficient method for a one-step ring opening and debenzylation reaction

Kovács, E., Thurner, A., Farkas, F., Faigl, F. & Hegeds, L., Apr 1 2011, In : Journal of Molecular Catalysis A: Chemical. 339, 1-2, p. 32-36 5 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Microwave-assisted esterification of phosphinic acids

Keglevich, G., Bálint, E., Kiss, N. Z., Jablonkai, E., Hegedüs, L., Grün, A. & Greiner, I., Jun 2011, In : Current Organic Chemistry. 15, 11, p. 1802-1810 9 p.

Research output: Contribution to journalArticle

53 Citations (Scopus)

Novel methods for the stereoselective synthesis of oxetane, azetidine and pyrrolidine derivatives

Faigl, F., Kovács, E., Turczel, G., Hegedus, L., Thurner, A., Farkas, F. & Szöllosy, Á., Nov 9 2011, In : IFMBE Proceedings. 37, p. 1366-1369 4 p.

Research output: Contribution to journalArticle

2010

Asymmetric epoxidation of substituted chalcones and chalcone analogues catalyzed by α-d-glucose- and α-d-mannose-based crown ethers

Makó, A., Rapi, Z., Keglevich, G., Szöllsy, Á., Drahos, L., Hegeds, L. & Bakó, P., Jun 11 2010, In : Tetrahedron Asymmetry. 21, 8, p. 919-925 7 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)

Hydrogenation of (±)-trans-2-arylnitrocyclohexane derivatives over palladium

Szántó, G., Kádas, I., Kárpáti, T. & Hegedűs, L., Feb 2010, In : Reaction Kinetics, Mechanisms and Catalysis. 99, 1, p. 85-92 8 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2009

An expedient total synthesis of ent-(-)-7-deoxy-trans-dihydronarciclasine

Szántó, G., Hegedus, L., Mattyasovszky, L., Simon, A., Simon, Á., Bitter, I., Tóth, G., Toke, L. & Kádas, I., Oct 3 2009, In : Tetrahedron. 65, 40, p. 8412-8417 6 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)

Hydrogenolysis of O-protected hydroxyoxetanes over palladium: An efficient method for a one-step ring opening and detritylation reaction

Farkas, F., Thurner, A., Kovács, E., Faigl, F. & Hegedus, L., Jan 25 2009, In : Catalysis Communications. 10, 5, p. 635-639 5 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Stereoselective total synthesis of (±)-7-deoxy-trans-dihydronarciclasine, a potent antineoplastic phenanthridone alkaloid

Szántó, G., Hegedus, L., Mattyasovszky, L., Simon, A., Simon, Á. & Kádas, I., Jun 17 2009, In : Tetrahedron Letters. 50, 24, p. 2857-2859 3 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)
2008

A rational synthesis of trans-2-(3-phenylprop-1-yl)cyclohexylamino-2-oxazoline enantiomers

Schindler, J., Faigl, F., Hegedus, L., Pálovics, E. & Fogassy, E., Apr 17 2008, In : Tetrahedron Asymmetry. 19, 7, p. 773-778 6 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
33 Citations (Scopus)
2006

A new, aluminium oxy-hydrate supported NiAl skeleton catalyst

Petró, J., Hegedus, L. & Sajó, I. E., Jul 10 2006, In : Applied Catalysis A: General. 308, p. 50-55 6 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
12 Citations (Scopus)
2005
62 Citations (Scopus)
2004

Hydrogenation of a 4-benzylpyridine derivative over supported precious metal catalysts

Proszenyák, Á., Ágai, B., Hegedus, L. & Faigl, F., Aug 18 2004, In : Applied Catalysis A: General. 269, 1-2, p. 249-253 5 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Novel 2-Phosphabicyclo[2.2.2]oct-5-ene Derivatives and Their Use in Phosphinylations

Keglevich, G., Kovács, J., Körtvélyesi, C., Parlagh, G., Imre, T., Ludányi, K., Hegedus, L., Hanusz, M., Simon, K., Márton, A., Marosi, G. & Toke, L., May 11 2004, In : Heteroatom Chemistry. 15, 2, p. 97-106 10 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2003

The first enantioselective synthesis of α-aminophosphinates

Szabó, A., Jászay, Z. M., Hegedus, L., Toke, L. & Petneházy, I., Jun 9 2003, In : Tetrahedron Letters. 44, 24, p. 4603-4606 4 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)
2002

Hydrogenation of pyrrole derivatives - Part V. Poisoning effect of nitrogen on precious metal on carbon catalysts

Hegedus, L. & Máthé, T., Mar 28 2002, In : Applied Catalysis A: General. 226, 1-2, p. 319-322 4 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)
2001

HPLC analysis of complete BZ systems. Evolution of the chemical composition in cerium and ferroin catalysed batch oscillators: Experiments and model calculations

Hegedűs, L., Wittmann, M., Noszticzius, Z., Yan, S., Sirimungkala, A., Försterling, H. D. & Field, R. J., Jan 1 2001, In : Faraday Discussions. 120, p. 21-38 18 p.

Research output: Contribution to journalArticle

68 Citations (Scopus)
2000
12 Citations (Scopus)

Chemical mechanism of the radical feedback loop in the classical BZ reaction. Malonyl bromite and oxalic acid as flow-through intermediates

Hegedus, L., Forsterling, H. D., Kokai, E., Pelle, K., Taba, G., Wittmann, M. & Noszticzius, Z., Sep 15 2000, In : Physical Chemistry Chemical Physics. 2, 18, p. 4023-4028 6 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Diastereoselective heterogeneous catalytic hydrogenation of N-heterocycles. Part I. Hydrogenation of pyridines

Hegedus, L., Háda, V., Tungler, A., Máthé, T. & Szepesy, L., Jun 26 2000, In : Applied Catalysis A: General. 201, 1, p. 107-114 8 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)

Effect of carbon support properties on enantioselective hydrogenation of isophorone over palladium catalysts modified with (-)-dihydroapovincaminic acid ethyl ester

Farkas, G., Hegedus, L., Tungler, A., Máthé, T., Figueiredo, J. L. & Freitas, M., Mar 10 2000, In : Journal of Molecular Catalysis A: Chemical. 153, 1-2, p. 215-219 5 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

Selective hydrogenation of exocyclic α,β-unsaturated ketones: Part I. Hydrogenations over palladium

Fogassy, G., Hegedus, L., Tungler, A., Lévai, A. & Máthé, T., Mar 20 2000, In : Journal of Molecular Catalysis A: Chemical. 154, 1-2, p. 237-241 5 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
20 Citations (Scopus)
1999

Alternative Reaction Channels and Carbene Intermediates in the Ce4+ - Malonic Acid and Ce4+ - Bromomalonic Acid Reactions. 1. CO2 Measurements

Nagygyory, S., Wittmann, M., Pintér, S., Visegrády, A., Dancsó, A., Thuy, N. B., Noszticzius, Z., Hegedus, L. & Försterling, H. D., Dec 1 1999, In : Journal of Physical Chemistry A. 103, 25, p. 4885-4892 8 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Diastereoselective and enantioselective heterogeneous catalytic hydrogenation of aminocinnamic acid derivatives

Tungler, A., Fürcht, Á., Karancsi, Z. P., Tóth, G., Máthé, T., Hegedús, L. & Sándi, Á., Mar 5 1999, In : Journal of Molecular Catalysis A: Chemical. 139, 2-3, p. 239-244 6 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Nonlinear effects of electrolyte diodes and transistors in a polymer gel medium

Hegedüs, L., Kirschner, N., Wittmann, M., Simon, P., Noszticzius, Z., Amemiya, T., Ohmori, T. & Yamaguchi, T., Jun 1999, In : Chaos. 9, 2, p. 283-297 15 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)
1998

Electrolyte transistors: Ionic reaction - Diffusion systems with amplifying properties

Hegedus, L., Kirschner, N., Wittmann, M. & Noszticzius, Z., Aug 6 1998, In : Journal of Physical Chemistry A. 102, 32, p. 6491-6497 7 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)

Failure tests of two-storey steel frames

Ivanyi, M., Hegedûs, L., Ivanyi, M. & Varga, G., Apr 1998, In : Journal of Constructional Steel Research. 46, 1-3, p. 86 1 p.

Research output: Contribution to journalArticle