• 1585 Citations
  • 22 h-Index
19982019

Research output per year

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Research Output

  • 1585 Citations
  • 22 h-Index
  • 55 Article
  • 2 Review article
1998

A General Synthesis of Disubstituted Rubicenes

Smet, M., Shukla, R., Fülöp, L. & Dehaen, W., Jan 1 1998, In : European Journal of Organic Chemistry. 12, p. 2769-2773 5 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)
2001

Synthesis and fluorescent labeling of beta-amyloid peptides

Fülöp, L., Penke, B. & Zarándi, M., Sep 5 2001, In : Journal of Peptide Science. 7, 8, p. 397-401 5 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)
2004

Enhanced G-protein activation by a mixture of Aβ(25-35), Aβ(1-40/42) and zinc

Molnár, Z., Kovács, P., Laczkó, I., Soós, K., Fülöp, L., Penket, B. & Lengyel, I., Jun 1 2004, In : Journal of neurochemistry. 89, 5, p. 1215-1223 9 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

In vitro model of neurotoxicity of Aβ 1-42 and neuroprotection by a pentapeptide: Irreversible events during the first hour

Datki, Z., Papp, R., Zádori, D., Soós, K., Fülöp, L., Juhász, A., Laskay, G., Hetényi, C., Mihalik, E., Zarándi, M. & Penke, B., Dec 1 2004, In : Neurobiology of Disease. 17, 3, p. 507-515 9 p.

Research output: Contribution to journalArticle

51 Citations (Scopus)

β-Amyloid-derived pentapeptide RIIGL a inhibits Aβ 1-42 aggregation and toxicity

Fülöp, L., Zarándi, M., Datki, Z., Soós, K. & Penke, B., Nov 5 2004, In : Biochemical and biophysical research communications. 324, 1, p. 64-69 6 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)
2005

Identification of synaptic plasma membrane proteins co-precipitated with fibrillar β-amyloid peptide

Verdier, Y., Huszár, E., Penke, B., Penke, Z., Woffendin, G., Scigelova, M., Fülöp, L., Szucs, M., Medzihradszky, K. & Janaky, T., Aug 1 2005, In : Journal of neurochemistry. 94, 3, p. 617-628 12 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Pentapeptides derived from Aβ1-42 protect neurons from the modulatory effect of Aβ fibrils-an in vitro and in vivo electrophysiological study

Szegedi, V., Fülöp, L., Farkas, T., Rózsa, E., Robotka, H., Kis, Z., Penke, Z., Horváth, S., Molnár, Z., Datki, Z., Soós, K., Toldi, J., Budai, D., Zarándi, M. & Penke, B., Apr 2005, In : Neurobiology of Disease. 18, 3, p. 499-508 10 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)
2006
100 Citations (Scopus)

Endomorphin-2, an endogenous tetrapeptide, protects against Aβ1-42 in vitro and in vivo

Szegedi, V., Juhá, G., Rózsa, É., Juhász-Vedres, G., Datki, Z., Fülöp, L., Bozsó, Z., Lakatos, A., Laczkó, I., Farkas, T., Kis, Z., Tóth, G., Soós, K., Zarándi, M., Budai, D., Toldi, J. & Penke, B., Jun 1 2006, In : FASEB Journal. 20, 8, p. E324-E333

Research output: Contribution to journalArticle

21 Citations (Scopus)

Non-fibrillar β-amyloid abates spike-timing-dependent synaptic potentiation at excitatory synapses in layer 2/3 of the neocortex by targeting postsynaptic AMPA receptors

Shemer, I., Holmgren, C., Min, R., Fülöp, L., Zilberter, M., Sousa, K. M., Farkas, T., Härtig, W., Penke, B., Burnashev, N., Tanila, H., Zilberter, Y. & Harkany, T., Apr 1 2006, In : European Journal of Neuroscience. 23, 8, p. 2035-2047 13 p.

Research output: Contribution to journalArticle

62 Citations (Scopus)
87 Citations (Scopus)
2007

Synthesis of Aβ(1-42) and its derivatives with improved efficiency

Zarándi, M., Soós, K., Fülöp, L., Bozsó, Z., Datki, Z., Tóth, G. K. & Penke, B., Feb 1 2007, In : Journal of Peptide Science. 13, 2, p. 94-99 6 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)
2008

Aggregation of Aβ(1-42) in the presence of short peptides: Conformational studies

Laczkó, I., Vass, E., Soós, K., FüLöp, L., Zarándi, M. & Penke, B., Jun 1 2008, In : Journal of Peptide Science. 14, 6, p. 731-741 11 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Characterization of the interaction between Aβ 1-42 and glyceraldehyde phosphodehydrogenase

Verdier, Y., Földi, I., Sergeant, N., Fülöp, L., Penke, Z., Janáky, T., Szücs, M. & Penke, B., Jun 1 2008, In : Journal of Peptide Science. 14, 6, p. 755-762 8 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Ligand-induced flocculation of neurotoxic fibrillar aβ (1-42) by noncovalent crosslinking

Hetényi, A., Fülöp, L., Martinek, T. A., Wéber, E., Soós, K. & Penke, B., Mar 25 2008, In : ChemBioChem. 9, 5, p. 748-757 10 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2009

Amyloid β-induced neuronal hyperexcitability triggers progressive epilepsy

Minkeviciene, R., Rheims, S., Dobszay, M. B., Zilberter, M., Hartikainen, J., Fülöp, L., Penke, B., Zilberter, Y., Harkany, T., Pitkänen, A. & Tanila, H., Mar 18 2009, In : Journal of Neuroscience. 29, 11, p. 3453-3462 10 p.

Research output: Contribution to journalArticle

321 Citations (Scopus)
16 Citations (Scopus)
2010
52 Citations (Scopus)

Controlled in situ preparation of Aβ(1-42) oligomers from the isopeptide "iso-Aβ(1-42)", physicochemical and biological characterization

Bozso, Z., Penke, B., Simon, D., Laczkó, I., Juhász, G., Szegedi, V., Kasza, Á., Soós, K., Hetényi, A., Wéber, E., Tóháti, H., Csete, M., Zarándi, M. & Fülöp, L., Feb 1 2010, In : Peptides. 31, 2, p. 248-256 9 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Effect of nanogold particles on coupled plasmon resonance on biomolecule covered prepatterned multilayers

Sipos, Á., Tóháti, H., Mathesz, A., Szalai, A., Budai, J., Deli, M. A., Fülöp, L., Köházi-Kis, A., Csete, M. & Bor, Z., Jun 1 2010, In : Sensor Letters. 8, 3, p. 512-520 9 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Fibrillar Aβ1-42enhances NMDA receptor sensitivity via the integrin signaling pathway

Juhász, G., Barkóczi, B., Vass, G., Datki, Z., Hunya, Á., Fülöp, L., Budai, D., Penke, B. & Szegedi, V., Jan 1 2010, In : Journal of Alzheimer's Disease. 19, 3, p. 1055-1067 13 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Functionalization of gold nanoparticles with amino acid, β-amyloid peptides and fragment

Majzik, A., Fülöp, L., Csapó, E., Bogár, F., Martinek, T., Penke, B., Bíró, G. & Dékány, I., Nov 1 2010, In : Colloids and Surfaces B: Biointerfaces. 81, 1, p. 235-241 7 p.

Research output: Contribution to journalArticle

99 Citations (Scopus)

Intranasal delivery of human β-amyloid peptide in rats: Effective brain targeting

Sipos, E., Kurunczi, A., Fehér, A., Penke, Z., Fülöp, L., Kasza, Á., Horváth, J., Horvát, S., Veszelka, S., Balogh, G., Kürti, L., Eros, I., Szabó-Révész, P., Párducz, Á., Penke, B. & Deli, M. A., Apr 1 2010, In : Cellular and Molecular Neurobiology. 30, 3, p. 405-413 9 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Protection of the blood-brain barrier by pentosan against amyloid-β-induced toxicity

Deli, M. A., Veszelka, S., Csiszár, B., Tóth, A., Kittel, Á., Csete, M., Sipos, Á., Szalai, A., Fülöp, L., Penke, B., Ábrahám, C. S. & Niwa, M., 2010, In : Journal of Alzheimer's Disease. 22, 3, p. 777-794 18 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Two pyridine derivatives as potential Cu(ii) and Zn(ii) chelators in therapy for Alzheimer's disease

Lakatos, A., Zsigó, É., Hollender, D., Nagy, N. V., Fülöp, L., Simon, D., Bozsó, Z. & Kiss, T., Feb 22 2010, In : Dalton Transactions. 39, 5, p. 1302-1315 14 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)
2011

Protein array based interactome analysis of amyloid-β indicates an inhibition of protein translation

Virok, D. P., Simon, D., Bozsó, Z., Rajkó, R., Datki, Z., Bálint, É., Szegedi, V., Janáky, T., Penke, B. & Fülöp, L., Apr 1 2011, In : Journal of Proteome Research. 10, 4, p. 1538-1547 10 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)
2012

A foldamer-dendrimer conjugate neutralizes synaptotoxic β-amyloid oligomers

Fülöp, L., Mándity, I. M., Juhász, G., Szegedi, V., Hetényi, A., Wéber, E., Bozsó, Z., Simon, D., Benko, M., Király, Z. & Martinek, T. A., Jul 30 2012, In : PloS one. 7, 7, e39485.

Research output: Contribution to journalArticle

31 Citations (Scopus)

Conformational dynamics of titin PEVK explored with FRET spectroscopy

Huber, T., Grama, L., Hetényi, C., Schay, G., Fülöp, L., Penke, B. & Kellermayer, M. S. Z., Oct 3 2012, In : Biophysical journal. 103, 7, p. 1480-1489 10 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Histidine-rich branched peptides as Cu(ii) and Zn(ii) chelators with potential therapeutic application in Alzheimer's disease

Lakatos, A., Gyurcsik, B., Nagy, N. V., Csendes, Z., Wéber, E., Fülöp, L. & Kiss, T., Feb 14 2012, In : Dalton Transactions. 41, 6, p. 1713-1726 14 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)

The formation of amyloid-like fibrils of αchymotrypsin in different aqueous organic solvents

Simon, L. M., Laczkó, I., Demcsák, A., Tóth, D., Kotormán, M. & Fülöp, L., May 1 2012, In : Protein and Peptide Letters. 19, 5, p. 544-550 7 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2013

Complement receptor type 1 (CR1, CD35) is a potent inhibitor of B-cell functions in rheumatoid arthritis patients

Kremlitzka, M., Polgár, A., Fülöp, L., Kiss, E., Poór, G. & Erdei, A., Jan 1 2013, In : International Immunology. 25, 1, p. 25-33 9 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Dietary energy substrates reverse early neuronal hyperactivity in a mouse model of Alzheimer's disease

Zilberter, M., Ivanov, A., Ziyatdinova, S., Mukhtarov, M., Malkov, A., Alpár, A., Tortoriello, G., Botting, C. H., Fülöp, L., Osypov, A. A., Pitkänen, A., Tanila, H., Harkany, T. & Zilberter, Y., Apr 1 2013, In : Journal of neurochemistry. 125, 1, p. 157-171 15 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)

Docosahexaenoic acid reduces amyloid-β induced toxicity in cells of the neurovascular unit

Veszelka, S., Tóth, A. E., Walter, F. R., Datki, Z., Mózes, E., Fülöp, L., Bozsó, Z., Hellinger, É., Vastag, M., Orsolits, B., Környei, Z., Penke, B. & Deli, M. A., 2013, In : Journal of Alzheimer's Disease. 36, 3, p. 487-501 15 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)
2014

Abeta(1-42) enhances neuronal excitability in the CA1 via NR2B subunit-containing NMDA receptors

Varga, E., Juhász, G., Bozsó, Z., Penke, B., Fülöp, L. & Szegedi, V., Jan 1 2014, In : Neural Plasticity. 2014, 584314.

Research output: Contribution to journalArticle

13 Citations (Scopus)
23 Citations (Scopus)

IKKβ deficiency in myeloid cells ameliorates Alzheimer's disease-related symptoms and pathology

Liu, Y., Liu, X., Hao, W., Decker, Y., Schomburg, R., Fülöp, L., Pasparakis, M., Menger, M. D. & Fassbender, K., Sep 24 2014, In : Journal of Neuroscience. 34, 39, p. 12982-12999 18 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)
13 Citations (Scopus)
2015
12 Citations (Scopus)

Amyloid-like fibril formation by trypsin in aqueous ethanol. inhibition of fibrillation by PEG

Kotormán, M., Simon, L. M., Borics, A., Szabó, M. R., Szabó, K., Szögi, T. & Fülöp, L., Dec 1 2015, In : Protein and Peptide Letters. 22, 12, p. 1104-1110 7 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Amyloid-β1-42 Disrupts Synaptic Plasticity by Altering Glutamate Recycling at the Synapse

Varga, E., Juhász, G., Bozsó, Z., Penke, B., Fülöp, L. & Szegedi, V., Jan 1 2015, In : Journal of Alzheimer's Disease. 45, 2, p. 449-456 8 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Opposite effect of Ca2+/Mg2+ ions on the aggregation of native and precursor-derived Aβ42

Bogár, F., Simon, D., Bozsó, Z., Janáky, T., Veszelka, S., Tóth, A. E., Deli, M. A., Borics, A., Násztor, Z., Gyebrovszki, A., Penke, B. & Fülöp, L., Dec 1 2015, In : Structural Chemistry. 26, 5-6, p. 1389-1403 15 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2016
21 Citations (Scopus)

Reversible Opening of Intercellular Junctions of Intestinal Epithelial and Brain Endothelial Cells with Tight Junction Modulator Peptides

Bocsik, A., Walter, F. R., Gyebrovszki, A., Fülöp, L., Blasig, I., Dabrowski, S., Ötvös, F., Tóth, A., Rákhely, G., Veszelka, S., Vastag, M., Szabó-Révész, P. & Deli, M., Feb 1 2016, In : Journal of Pharmaceutical Sciences. 105, 2, p. 754-765 12 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)
2017

Biotin and glutathione targeting of solid nanoparticles to cross human brain endothelial cells

Veszelka, S., Mészáros, M., Kiss, L., Kóta, Z., Páli, T., Hoyk, Z., Bozsó, Z., Fülöp, L., Tóth, A., Rákhely, G. & Deli, M. A., Aug 1 2017, In : Current pharmaceutical design. 23, 28, p. 4198-4205 8 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

New small-size peptides modulators of the exosite of BACE1 obtained from a structure-based design

Gutierrez, L. J., Angelina, E., Gyebrovszki, A., Fülöp, L., Peruchena, N., Baldoni, H. A., Penke, B. & Enriz, R. D., Jan 25 2017, In : Journal of Biomolecular Structure and Dynamics. 35, 2, p. 413-426 14 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Studies for improving a rat model of Alzheimer's disease: ICV administration of well-characterized β-amyloid 1-42 oligomers induce dysfunction in spatial memory

Kasza, Á., Penke, B., Frank, Z., Bozsó, Z., Szegedi, V., Hunya, Á., Németh, K., Kozma, G. & Fülöp, L., Nov 2017, In : Molecules. 22, 11, 2007.

Research output: Contribution to journalArticle

16 Citations (Scopus)
2018

Exceptional in vivo catabolism of neurodegeneration-related aggregates

Datki, Z., Olah, Z., Hortobagyi, T., Macsai, L., Zsuga, K., Fulop, L., Bozso, Z., Galik, B., Acs, E., Foldi, A., Szarvas, A. & Kalman, J., Jan 1 2018, In : Zoological Letters. 4, 1, 6.

Research output: Contribution to journalArticle

3 Citations (Scopus)

GABAA receptor subunit deregulation in the hippocampus of human foetuses with Down syndrome

Milenkovic, I., Stojanovic, T., Aronica, E., Fülöp, L., Bozsó, Z., Máté, Z., Yanagawa, Y., Adle-Biassette, H., Lubec, G., Szabó, G., Harkany, T., Kovács, G. G. & Keimpema, E., Apr 1 2018, In : Brain Structure and Function. 223, 3, p. 1501-1518 18 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Niosomes decorated with dual ligands targeting brain endothelial transporters increase cargo penetration across the blood-brain barrier

Mészáros, M., Porkoláb, G., Kiss, L., Pilbat, A. M., Kóta, Z., Kupihár, Z., Kéri, A., Galbács, G., Siklós, L., Tóth, A., Fülöp, L., Csete, M., Sipos, Á., Hülper, P., Sipos, P., Páli, T., Rákhely, G., Szabó-Révész, P., Deli, M. A. & Veszelka, S., Oct 15 2018, In : European Journal of Pharmaceutical Sciences. 123, p. 228-240 13 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Peripheral cyclic β-amino acids balance the stability and edge-protection of β-sandwiches

Olajos, G., Hetényi, A., Wéber, E., Szögi, T., Fülöp, L. & Martinek, T. A., Jan 1 2018, In : Organic and Biomolecular Chemistry. 16, 30, p. 5492-5499 8 p.

Research output: Contribution to journalArticle