• 4888 Citations
  • 30 h-Index
1986 …2019

Research output per year

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Research Output

  • 4888 Citations
  • 30 h-Index
  • 66 Article
  • 5 Review article
  • 2 Short survey
2019

Dendritic spine morphology and memory formation depend on postsynaptic Caskin proteins

Bencsik, N., Pusztai, S., Borbély, S., Fekete, A., Dülk, M., Kis, V., Pesti, S., Vas, V., Szűcs, A., Buday, L. & Schlett, K., Dec 1 2019, In : Scientific reports. 9, 1, 16843.

Research output: Contribution to journalArticle

Open Access

Significance of the Tks4 scaffold protein in bone tissue homeostasis

Vas, V., Kovács, T., Körmendi, S., Bródy, A., Kudlik, G., Szeder, B., Mező, D., Kállai, D., Koprivanacz, K., Merő, B. L., Dülk, M., Tóvári, J., Vajdovich, P., Şenel, N., Özcan, I., Helyes, Z., Dobó-Nagy, C. & Buday, L., Dec 1 2019, In : Scientific reports. 9, 1, 5781.

Research output: Contribution to journalArticle

Open Access

Structural insights into the tyrosine phosphorylation–mediated inhibition of SH3 domain–ligand interactions

Mero, B., Radnai, L., Gógl, G., To ke, O., Leveles, I., Koprivanacz, K., Szeder, B., Dülk, M., Kudlik, G., Virág Vas, X., Cserkaszky, A., Sipeki, S., Nyitray, L., Vértessy, B. & Buday, L., Jan 1 2019, In : Journal of Biological Chemistry. 294, 12, p. 4608-4620 13 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2018

Disordered Regions of Mixed Lineage Leukemia 4 (MLL4) Protein Are Capable of RNA Binding

Szabó, B., Murvai, N., Abukhairan, R., Schád, É., Kardos, J., Szeder, B., Buday, L. & Tantos, Á., Nov 5 2018, In : International Journal of Molecular Sciences. 19, 11

Research output: Contribution to journalArticle

1 Citation (Scopus)

Dynamic control of RSK complexes by phosphoswitch-based regulation

Gógl, G., Biri-Kovács, B., Póti, Á. L., Vadászi, H., Szeder, B., Bodor, A., Schlosser, G., Ács, A., Turiák, L., Buday, L., Alexa, A., Nyitray, L. & Reményi, A., Jan 2018, In : FEBS Journal. 285, 1, p. 46-71 26 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

EGF Regulates the Interaction of Tks4 with Src through Its SH2 and SH3 Domains

Dülk, M., Szeder, B., Glatz, G., Merö, B. L., Koprivanacz, K., Kudlik, G., Vas, V., Sipeki, S., Cserkaszky, A., Radnai, L. & Buday, L., Jul 17 2018, In : Biochemistry. 57, 28, p. 4186-4196 11 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Enhanced in vitro antitumor activity of gnRH-III-daunorubicin bioconjugates influenced by sequence modification

Schuster, S., Biri-Kovács, B., Szeder, B., Buday, L., Gardi, J., Szabó, Z., Halmos, G. & Mező, G., Dec 1 2018, In : Pharmaceutics. 10, 4, 223.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Synthesis and in vitro biochemical evaluation of oxime bond-linked daunorubicin-GnRH-III conjugates developed for targeted drug delivery

Schuster, S., Biri-Kovács, B., Szeder, B., Farkas, V., Buday, L., Szabó, Z., Halmos, G. & Mező, G., Jan 1 2018, In : Beilstein Journal of Organic Chemistry. 14, p. 756-771 16 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2017

Regulation of the Equilibrium between Closed and Open Conformations of Annexin A2 by N-Terminal Phosphorylation and S100A4-Binding

Ecsédi, P., Kiss, B., Gógl, G., Radnai, L., Buday, L., Koprivanacz, K., Liliom, K., Leveles, I., Vértessy, B., Jeszenői, N., Hetényi, C., Schlosser, G., Katona, G. & Nyitray, L., Aug 1 2017, In : Structure. 25, 8, p. 1195-1207.e5

Research output: Contribution to journalArticle

14 Citations (Scopus)
2016

Mesenchymal stem cells promote macrophage polarization toward M2b-like cells

Kudlik, G., Hegyi, B., Czibula, A., Monostori, E., Buday, L. & Uher, F., Oct 15 2016, In : Experimental Cell Research. 348, 1, p. 36-45 10 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

The scaffold protein Tks4 is required for the differentiation of mesenchymal stromal cells (MSCs) into adipogenic and osteogenic lineages

Dülk, M., Kudlik, G., Fekete, A., Ernszt, D., Kvell, K., Pongrácz, J., Mero, B. L., Szeder, B., Radnai, L., Geiszt, M., Csécsy, D. E., Kovács, T., Uher, F., Lányi, A., Vas, V. & Buday, L., Oct 6 2016, In : Scientific Reports. 6, 34280.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2015

Accumulation of the PX domain mutant Frank-ter Haar syndrome protein Tks4 in aggresomes

Ádám, C., Fekete, A., Bogel, G., Németh, Z., Tokési, N., Ovádi, J., Liliom, K., Pesti, S., Geiszt, M. & Buday, L., Jul 17 2015, In : Cell Communication and Signaling. 13, 1, 33.

Research output: Contribution to journalArticle

2 Citations (Scopus)

K153R polymorphism in myostatin gene increases the rate of promyostatin activation by furin

Szláma, G., Trexler, M., Buday, L. & Patthy, L., Jan 30 2015, In : FEBS letters. 589, 3, p. 295-301 7 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

T cell specific adaptor protein (TSAd) promotes interaction of Nck with Lck and SLP-76 in T cells

Hem, C. D., Sundvold-Gjerstad, V., Granum, S., Koll, L., Abrahamsen, G., Buday, L. & Spurkland, A., Jul 11 2015, In : Cell Communication and Signaling. 13, 1, 31.

Research output: Contribution to journalArticle

10 Citations (Scopus)
2014

Dynamics of re-constitution of the human nuclear proteome after cell division is regulated by NLS-adjacent phosphorylation

Róona, G., Borsos, M., Ellis, J. J., Mehdi, A. M., Christie, M., Köornyei, Z., Neubrandt, M., Tóoth, J., Bozóoky, Z., Buday, L., Madaráasz, E., Bodáen, M., Kobe, B. & Véertessy, B. G., Nov 15 2014, In : Cell Cycle. 13, 22, p. 3551-3564 14 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)
2013

EGF regulates tyrosine phosphorylation and membrane-translocation of the scaffold protein Tks5

Fekete, A., Bogel, G., Pesti, S., Péterfi, Z., Geiszt, M. & Buday, L., Aug 7 2013, In : Journal of Molecular Signaling. 8, 8.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Phosphorylation adjacent to the nuclear localization signal of human dUTPase abolishes nuclear import: Structural and mechanistic insights

Róna, G., Marfori, M., Borsos, M., Scheer, I., Takács, E., Tóth, J., Babos, F., Magyar, A., Erdei, A., Bozóky, Z., Buday, L., Kobe, B. & Vértessy, B. G., Dec 1 2013, In : Acta Crystallographica Section D: Biological Crystallography. 69, 12, p. 2495-2505 11 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Silicon carbide quantum dots for bioimaging

Beke, D., Szekrényes, Z., Pálfi, D., Róna, G., Balogh, I., Maák, P. A., Katona, G., Czigány, Z., Kamarás, K., Rózsa, B., Buday, L., Vértessy, B. & Gali, A., Jan 28 2013, In : Journal of Materials Research. 28, 2, p. 205-209 5 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)
2012

Complex formation of EphB1/Nck/Caskin1 leads to tyrosine phosphorylation and structural changes of the Caskin1 SH3 domain

Pesti, S., Balázs, A., Udupa, R., Szabó, B., Fekete, A., Bögel, G. & Buday, L., Dec 1 2012, In : Cell Communication and Signaling. 10, 36.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Frank-ter Haar syndrome protein Tks4 regulates epidermal growth factor-dependent cell migration

Bögel, G., Gujdár, A., Geiszt, M., Lányi, Á., Fekete, A., Sipeki, S., Downward, J. & Buday, L., Sep 7 2012, In : Journal of Biological Chemistry. 287, 37, p. 31321-31329 9 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)
2011

Isoenzyme selective phosphoinositide 3-kinase inhibition: What do the stones kill?

Buday, L. & Sipeki, S., Sep 1 2011, In : Current Signal Transduction Therapy. 6, 3, p. 405-410 6 p.

Research output: Contribution to journalArticle

The homolog of the five SH3-domain protein (HOFI/SH3PXD2B) regulates lamellipodia formation and cell spreading

Lányi, Á., Baráth, M., Péterfi, Z., Bögel, G., Orient, A., Simon, T., Petrovszki, E., Kis-Tóth, K., Sirokmány, G., Rajnavölgyi, É., Terhorst, C., Buday, L. & Geiszt, M., Aug 23 2011, In : PloS one. 6, 8, e23653.

Research output: Contribution to journalArticle

20 Citations (Scopus)

The signaling pathway of Campylobacter jejuni-induced Cdc42 activation: Role of fibronectin, integrin beta1, tyrosine kinases and guanine exchange factor Vav2

Krause-Gruszczynska, M., Boehm, M., Rohde, M., Tegtmeyer, N., Takahashi, S., Buday, L., Oyarzabal, O. A. & Backert, S., Dec 1 2011, In : Cell Communication and Signaling. 9, 32.

Research output: Contribution to journalArticle

38 Citations (Scopus)
2010

Accessory proteins in signal transduction: Scaffold proteins and beyond

Buday, L. & Tompa, P., Nov 1 2010, In : FEBS Journal. 277, 21, 1 p.

Research output: Contribution to journalShort survey

5 Citations (Scopus)

Affinity, avidity, and kinetics of target sequence binding to LC8 dynein light chain isoforms

Radnai, L., Rapali, P., Hódi, Z., Süveges, D., Molnár, T., Kiss, B., Bécsi, B., Erdödi, F., Buday, L., Kardos, J., Kovács, M. & Nyitray, L., Dec 3 2010, In : Journal of Biological Chemistry. 285, 49, p. 38649-38657 9 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

Angiotensin II-induced expression of brain-derived neurotrophic factor in human and rat adrenocortical cells

Szekeres, M., Nádasy, G. L., Turu, G., Süpeki, K., Szidonya, L., Buday, L., Chaplin, T., Clark, A. J. L. & Hunyady, L., Apr 1 2010, In : Endocrinology. 151, 4, p. 1695-1703 9 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Functional classification of scaffold proteins and related molecules

Buday, L. & Tompa, P., Nov 1 2010, In : FEBS Journal. 277, 21, p. 4348-4355 8 p.

Research output: Contribution to journalShort survey

49 Citations (Scopus)

Small-molecule inhibitors of NADPH oxidase 4

Borbély, G., Szabadkai, I., Horváth, Z., Markó, P., Varga, Z., Breza, N., Baska, F., Vántus, T., Huszár, M., Geiszt, M., Hunyady, L., Buday, L., Örfi, L. & Kéri, G., Sep 23 2010, In : Journal of Medicinal Chemistry. 53, 18, p. 6758-6762 5 p.

Research output: Contribution to journalArticle

41 Citations (Scopus)

The ERK1/2-hepatocyte nuclear factor 4α axis regulates human ABCC6 gene expression in hepatocytes

De Boussac, H., Ratajewski, M., Sachrajda, I., Köblös, G., Tordai, A., Pulaski, L., Buday, L., Váradi, A. & Arányi, T., Jul 23 2010, In : Journal of Biological Chemistry. 285, 30, p. 22800-22808 9 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)
2009

Detection of hydrogen peroxide by lactoperoxidase-mediated dityrosine formation

Donkó, Á., Orient, A., Szabó, P. T., Németh, G., Vántus, T., Kéri, G., Örfi, L., Hunyady, L., Buday, L. & Geiszt, M., Jul 20 2009, In : Free Radical Research. 43, 5, p. 440-445 6 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

High levels of structural disorder in scaffold proteins as exemplified by a novel neuronal protein, CASK-interactive protein1

Balázs, A., Csizmok, V., Buday, L., Rakács, M., Kiss, R., Bokor, M., Udupa, R., Tompa, K. & Tompa, P., Jul 2009, In : FEBS Journal. 276, 14, p. 3744-3756 13 p.

Research output: Contribution to journalArticle

52 Citations (Scopus)

Intrinsic structural disorder confers cellular viability on oncogenic fusion proteins

Hegyi, H., Buday, L. & Tompa, P., Oct 1 2009, In : PLoS computational biology. 5, 10, e1000552.

Research output: Contribution to journalArticle

56 Citations (Scopus)

Specific tyrosine phosphorylation of focal adhesion kinase mediated by Fer tyrosine kinase in suspended hepatocytes

Oh, M. A., Choi, S., Lee, M. J., Choi, M. C., Lee, S. A., Ko, W., Cance, W. G., Oh, E. S., Buday, L., Kim, S. H. & Lee, J. W., May 1 2009, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1793, 5, p. 781-791 11 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2008

Many faces of Ras activation

Buday, L. & Downward, J., Dec 1 2008, In : Biochimica et Biophysica Acta - Reviews on Cancer. 1786, 2, p. 178-187 10 p.

Research output: Contribution to journalReview article

127 Citations (Scopus)
2007

Roles of cortactin in tumor pathogenesis

Buday, L. & Downward, J., Jun 1 2007, In : Biochimica et Biophysica Acta - Reviews on Cancer. 1775, 2, p. 263-273 11 p.

Research output: Contribution to journalReview article

78 Citations (Scopus)
2006

Cortactin is required for integrin-mediated cell spreading

Illés, A., Enyedi, B., Tamás, P., Balázs, A., Bogel, G., Melinda, Lukács & Buday, L., Apr 15 2006, In : Immunology letters. 104, 1-2, p. 124-130 7 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Differential β-arrestin binding of AT1 and AT2 angiotensin receptors

Turu, G., Szidonya, L., Gáborik, Z., Buday, L., Spät, A., Clark, A. J. L. & Hunyady, L., Jan 9 2006, In : FEBS letters. 580, 1, p. 41-45 5 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)

Inducible phosphorylation of cortactin is not necessary for cortactin-mediated actin polymerisation

Illés, A., Enyedi, B., Tamás, P., Balázs, A., Bogel, G. & Buday, L., Jun 1 2006, In : Cellular Signalling. 18, 6, p. 830-840 11 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)
2005
191 Citations (Scopus)

Selective cellular effects of overexpressed pleckstrin-homology domains that recognize Ptdlns(3,4,5)P3 suggest their interaction with protein binding partners

Várni, P., Bondeva, T., Tamás, P., Tóth, B., Buday, L., Hunyady, L. & Balla, T., Oct 15 2005, In : Journal of cell science. 118, 20, p. 4879-4888 10 p.

Research output: Contribution to journalArticle

103 Citations (Scopus)

Structural disorder throws new light on moonlighting

Tompa, P., Szász, C. & Buday, L., Sep 2005, In : Trends in Biochemical Sciences. 30, 9, p. 484-489 6 p.

Research output: Contribution to journalArticle

357 Citations (Scopus)
2004

Protein kinase C modulates negatively the hepatocyte growth factor-induced migration, integrin expression and phosphatidylinositol 3-kinase activation

Gujdár, A., Sipeki, S., Bander, E., Buday, L. & Faragó, A., Apr 2004, In : Cellular Signalling. 16, 4, p. 505-513 9 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2003

Mechanism of epidermal growth factor regulation of Vav2, a guanine nucleotide exchange factor for Rac

Tamás, P., Solti, Z., Bauer, P., Illés, A., Sipeki, S., Bauer, A., Faragó, A., Downward, J. & Buday, L., Feb 14 2003, In : Journal of Biological Chemistry. 278, 7, p. 5163-5171 9 p.

Research output: Contribution to journalArticle

92 Citations (Scopus)
15 Citations (Scopus)
2002

The Nck family of adapter proteins: Regulators of actin cytoskeleton

Buday, L., Wunderlich, L. & Tamás, P., Jun 17 2002, In : Cellular Signalling. 14, 9, p. 723-731 9 p.

Research output: Contribution to journalReview article

171 Citations (Scopus)
2001

Membrane-targeting is critical for the phosphorylation of Vav2 by activated EGF receptor

Tamás, P., Solti, Z. & Buday, L., Jun 27 2001, In : Cellular Signalling. 13, 7, p. 475-481 7 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)
1999

Association of Nck with tyrosine-phosphorylated SLP-76 in activated T lymphocytes

Wunderlich, L., Faragó, A., Downward, J. & Buday, L., Apr 19 1999, In : European journal of immunology. 29, 4, p. 1068-1075 8 p.

Research output: Contribution to journalArticle

74 Citations (Scopus)

Characterization of interactions of Nck with Sos and dynamin

Wunderlich, L., Faragó, A. & Buday, L., Jan 1 1999, In : Cellular Signalling. 11, 1, p. 25-29 5 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

Membrane-targeting of signalling molecules by SH2/SH3 domain-containing adaptor proteins

Buday, L., Jul 6 1999, In : Biochimica et Biophysica Acta - Reviews on Biomembranes. 1422, 2, p. 187-204 18 p.

Research output: Contribution to journalReview article

122 Citations (Scopus)

Phosphatidylinositol 3-kinase contributes to Erk1/Erk2 MAP kinase activation associated with hepatocyte growth factor-induced cell scattering

Sipeki, S., Bander, E., Buday, L., Farkas, G., Bácsy, E., Ways, D. K. & Faragó, A., Dec 1 1999, In : Cellular Signalling. 11, 12, p. 885-890 6 p.

Research output: Contribution to journalArticle

55 Citations (Scopus)