• 1589 Citations
  • 23 h-Index
1977 …2019

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

  • 1589 Citations
  • 23 h-Index
  • 109 Article
  • 21 Review article
  • 2 Letter
  • 1 Chapter
Filter
Article
2019

An update of SGLT1 and SGLT2 inhibitors in early phase diabetes-type 2 clinical trials

Adeghate, E., Mohsin, S., Adi, F., Ahmed, F., Yahya, A., Kalász, H., Tekes, K. & Adeghate, E. A., Sep 2 2019, In : Expert Opinion on Investigational Drugs. 28, 9, p. 811-820 10 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

An update on therapies for the treatment of diabetes-induced osteoporosis

Mohsin, S., Baniyas, M. M. Y. H., AlDarmaki, R. S. M. H., Tekes, K., Kalász, H. & Adeghate, E. A., Jan 1 2019, In : Expert Opinion on Biological Therapy.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Circulating nociceptin and CGRP in medication-overuse headache

Munksgaard, S. B., Ertsey, C., Frandsen, E., Bendtsen, L., Tekes, K. & Jensen, R. H., Mar 2019, In : Acta Neurologica Scandinavica. 139, 3, p. 269-275 7 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Dose-dependent tissue distribution of K117, a bis-pyridinium aldoxime, in rats

Kalász, H., Karvaly, G., Musilek, K., Kuca, K., Young-Sik, J., Malawska, B., Adeghate, E. A., Nurulain, S. M., Szepesy, J., Zelles, T. & Tekes, K., Jan 1 2019, In : Open Medicinal Chemistry Journal. 13, 1, p. 1-6 6 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Pharmacokinetics of K117 and K127, two novel antidote candidates to treat Tabun poisoning

Tekes, K., Karvaly, G., Nurulain, S., Kuca, K., Musilek, K., Adeghate, E., Jung, Y. S. & Kalász, H., Sep 1 2019, In : Chemico-Biological Interactions. 310, 108737.

Research output: Contribution to journalArticle

2018

Effect of nociceptin on insulin release in normal and diabetic rat pancreas

Adeghate, E., Saeed, Z., D’Souza, C., Tariq, S., Kalász, H., Tekes, K. & Adeghate, E. A., Dec 1 2018, In : Cell And Tissue Research. 374, 3, p. 517-529 13 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2017

Effects on sperms’ quality of selegiline in aged rats

Kalász, H., Thuróczy, J., Karvaly, G., Balogh, L., Gyertyán, I., Molnár, E. T., Adeghate, E. & Tekes, K., Nov 1 2017, In : Open Medicinal Chemistry Journal. 11, p. 138-145 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

HPLC analysis and blood-brain penetration of 20-hydroxyecdysone diacetonide

Kalasz, H., Hunyadi, A., Tekes, K., Dolesal, R. & Karvaly, G., Sep 2017, In : Acta Chromatographica. 29, 3, p. 375-383 9 p.

Research output: Contribution to journalArticle

Monitoring the level of 14C-labelled selegiline following oral administration

Kalász, H., Tekes, K., Faigl, E. B., Pöstényi, Z., Berekméri, E., Karvaly, G. & Adeghate, E., Jan 1 2017, In : Open Medicinal Chemistry Journal. 11, p. 1-8 8 p.

Research output: Contribution to journalArticle

2016

Diabetes-induced changes in the morphology and nociceptinergic innervation of the rat uterus

Tariq, S., Nurulain, S. M., Rashed, H., Lotfy, M., Emerald, S. B., Koturan, S., Tekes, K. & Adeghate, E., Feb 1 2016, In : Journal of Molecular Histology. 47, 1, p. 21-33 13 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Pharmacokinetics of selegiline in a rabbit model

Kalász, H., Tekes, K., Pöstényi, Z., Vizvári, E., Sótonyi, P., Szabó, D. & Tóth-Molnár, E., Oct 1 2016, In : Letters in Drug Design and Discovery. 13, 8, p. 752-756 5 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2015

Distribution of N-methyl-14C-labeled selegiline in the rat

Tekes, K., Pöstényi, Z., Faigl, E. B., Magyar, K., Polyák, A., Trencsényi, G., Balogh, L. & Kalász, H., Jul 1 2015, In : Journal of Pharmaceutical and Biomedical Analysis. 111, p. 147-152 6 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Distribution of nociceptin in pancreatic islet cells of normal and diabetic rats

Tariq, S., Rashed, H., Nurulain, S. M., Emerald, B. S., Koturan, S., Tekes, K. & Adeghate, E., May 25 2015, In : Pancreas. 44, 4, p. 602-607 6 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Efficacy of N-Acetylcysteine, Glutathione, and Ascorbic Acid in Acute Toxicity of Paraoxon to Wistar Rats: Survival Study

Nurulain, S. M., Ojha, S., Tekes, K., Shafiullah, M., Kalasz, H. & Adem, A., Jan 1 2015, In : Oxidative medicine and cellular longevity. 2015, 329306.

Research output: Contribution to journalArticle

4 Citations (Scopus)

HPLC analysis of blood-brain barrier penetration of 4-fluorodeprenyl

Pöstényi, Z., Tekes, K., Tóth-Molnár, E. & Kalász, H., Jan 5 2015, In : Journal of Pharmaceutical and Biomedical Analysis. 102, p. 529-534 6 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2014

HPLC analysis and detection of L-deprenyl

Csomor, V., Laufer, R., Pöstényi, Z., Kalász, H., Adeghate, E., Nurulain, S. M., Tekes, K. & Adem, A., Dec 1 2014, In : Acta Chromatographica. 26, 4, p. 649-656 8 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

HPLC determination of brain biogenic amines following treatment with bispyridinium aldoxime K203

Hashemi, F., Laufer, R., Szegi, P., Csomor, V., Kalász, H. & Tekes, K., Mar 1 2014, In : Acta physiologica Hungarica. 101, 1, p. 40-46 7 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2013
26 Citations (Scopus)

HPLC analysis in drug level monitoring of K027

Nurulain, S., Kalász, H., Szegi, P., Kuca, K., Adem, A., Hasan, M., Hashemi, F. & Tekes, K., Dec 1 2013, In : Acta Chromatographica. 25, 4, p. 703-710 8 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Medicinal chemistry of antimigraine drugs

Tekes, K., Szegi, P., Hashemi, F., Laufer, R., Kalász, H., Siddiq, A. & Ertsey, C., Sep 1 2013, In : Current medicinal chemistry. 20, 26, p. 3300-3316 17 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Nociceptinergic system as potential target in Parkinson's disease

Tekes, K., Tariq, S., Adeghate, E., Laufer, R., Hashemi, F., Siddiq, A. & Kalasz, H., Aug 20 2013, In : Mini-Reviews in Medicinal Chemistry. 13, 10, p. 1389-1397 9 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Nocistatin inhibits pregnant rat uterine contractions in vitro: Roles of calcitonin gene-related peptide and calcium-dependent potassium channel

Deák, B. H., Klukovits, A., Tekes, K., Ducza, E., Falkay, G. & Gáspár, R., Jan 1 2013, In : European Journal of Pharmacology. 714, 1-3, p. 96-104 9 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Study on medicinal chemistry of k203 in wistar rats and beagle dogs

Kalász, H., Szegi, P., Jánoki, G., Balogh, L., Pöstényi, Z., Musilek, K., Petroianu, G. A., Siddiq, A. & Tekes, K., May 1 2013, In : Current medicinal chemistry. 20, 16, p. 2137-2144 8 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2011

Aliphatic and aromatic oxidations, epoxidation and s-oxidation of prodrugs that yield active drug metabolites

Tekes, K., Kalász, H., Hasan, M. Y., Adeghate, E., Darvas, F., Ram, N. & Adem, A., Nov 1 2011, In : Current medicinal chemistry. 18, 32, p. 4885-4900 16 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Antidepresszánsok és aktív metabolitjaik sorsa a szervezetben

Translated title of the contribution: Prodrugs and active metabolites among antidepressive compoundsTekes, K., Hashemi, F., Szegi, P., Sótonyi, P., Laufer, R. & Kalász, H., Jun 1 2011, In : Neuropsychopharmacologia Hungarica. 13, 2, p. 103-110 8 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Effect of perinatal stress on the biogenic amine neurotransmitter level of the adult rat's brain

Tekes, K., Szegi, P., Laufer, R., Hantos, M. & Csaba, G., Apr 1 2011, In : International Journal of Developmental Neuroscience. 29, 2, p. 171-175 5 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Plasma nociceptin/orphanin FQ levels are lower in patients with chronic ischemic cardiovascular diseases-A pilot study

Krepuska, M., Sótonyi, P., Csobay-Novák, C., Szeberin, Z., Hartyánszky, I., Zima, E., Szilágyi, N., Horkay, F., Merkely, B., Acsády, G. & Tekes, K., Aug 8 2011, In : Regulatory Peptides. 169, 1-3, p. 1-5 5 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
2010

Activation of 5-HT3 receptors leads to altered responses 6 months after MDMA treatment

Gyongyosi, N., Balogh, B., Katai, Z., Molnar, E., Laufer, R., Tekes, K. & Bagdy, G., Mar 1 2010, In : Journal of neural transmission. 117, 3, p. 285-292 8 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Medicinal chemistry of antiviral/anticancer prodrugs subjected to phosphate conjugation

Kalász, H., Adem, A., Hasan, M. Y., Adeghate, E., Ram, N., Gulyás, Z. & Tekes, K., Jan 1 2010, In : Mini-Reviews in Medicinal Chemistry. 10, 9, p. 822-845 24 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Nociceptin inhibits uterine contractions in term-pregnant rats by signaling through multiple pathways

Klukovits, A., Tekes, K., Gündüz Çinar, Ö., Benyhe, S., Borsodi, A., Deák, B. H., Hajagos-Tóth, J., Verli, J., Falkay, G. & Gáspár, R., Jul 2010, In : Biology of Reproduction. 83, 1, p. 36-41 6 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Pyridinium aldoxime analysis by HPLC: The method for studies on pharmacokinetics and stability

Szegi, P., Kalász, H., Laufer, R., Kuca, K. & Tekes, K., May 1 2010, In : Analytical and Bioanalytical Chemistry. 397, 2, p. 579-586 8 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Synthesis, antidotal effects and HPLC behavior of some novel pyridinium aldoximes

Laufer, R., Kalász, H., Musilek, K., Szegi, P., Darvas, F., Kuca, K. & Tekes, K., Jul 30 2010, In : Current Organic Chemistry. 14, 5, p. 447-456 10 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
2009

Analysis of pralidoxime in serum, brain and CSF of rats

Kalász, H., Szöko, É., Tábi, T., Petroianu, G. A., Lorke, D. E., Omar, A., Alafifi, S., Jasem, A. & Tekes, K., Sep 18 2009, In : Medicinal Chemistry. 5, 3, p. 237-241 5 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)
11 Citations (Scopus)

HPLC monitoring of the microsomal stability of rutin and quercetin

Szöke, É., Petroianu, G., Tekes, K., Benko, B., Szegi, P., Laufer, R. & Veress, G., Sep 1 2009, In : Acta Chromatographica. 21, 3, p. 399-410 12 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
37 Citations (Scopus)
11 Citations (Scopus)

Lipophilicity determination using both TLC and calculations

Kalász, H., Benko, B., Gulyás, Z. & Tekes, K., Oct 19 2009, In : Journal of Liquid Chromatography and Related Technologies. 32, 9, p. 1342-1358 17 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Monitoring by HPLC of chamomile flavonoids exposed to rat liver microsomal metabolism

Petroianu, G., Szoke, É., Kalász, H., Szegi, P., Laufer, R., Benkco, B., Darvas, F. & Tekes, K., Sep 24 2009, In : Open Medicinal Chemistry Journal. 3, p. 1-7 7 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Monitoring the pharmacokinetics of pyridinium aldoximes in the body

Kalász, H., Furész, J. & Tekes, K., Sep 21 2009, In : Mini-Reviews in Medicinal Chemistry. 9, 5, p. 596-610 15 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
30 Citations (Scopus)
2008
Open Access
14 Citations (Scopus)

HPLC study of the pharmacokinetics of K-203

Kalász, H., Laufer, R., Szegi, P., Kuca, K., Musilek, K. & Tekes, K., Dec 1 2008, In : Acta Chromatographica. 20, 4, p. 575-584 10 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Nocistatin and nociceptin given centrally induce opioid-mediated gastric mucosal protection

Zádori, Z. S., Shujaa, N., Köles, L., Király, K. P., Tekes, K. & Gyires, K., Dec 1 2008, In : Peptides. 29, 12, p. 2257-2265 9 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)
2007
8 Citations (Scopus)

Effect of β-endorphin imprinting during late pregnancy on the brain serotonin and plasma nocistatin levels of adult male rats

Tekes, K., Cyenge, M., Hantos, M. & Csaba, C., Jul 1 2007, In : Hormone and Metabolic Research. 39, 7, p. 479-481 3 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

In vitro and in vivo metabolisms of K-48

Benkő, B., Kalász, H., Ludányi, K., Petroianu, G., Kuca, K., Darvas, F. & Tekes, K., Oct 2007, In : Analytical and Bioanalytical Chemistry. 389, 4, p. 1243-1247 5 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Measurement of K-27, an oxime-type cholinesterase reactivator by high-performance liquid chromatography with electrochemical detection from different biological samples

Gyenge, M., Kalász, H., Petroianu, G. A., Laufer, R., Kuca, K. & Tekes, K., Aug 17 2007, In : Journal of Chromatography A. 1161, 1-2, p. 146-151 6 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Metabolism of moexipril to moexiprilat: Determination of in vitro metabolism using HPLC-ES-MS

Kalász, H., Petroianu, G., Tekes, K., Klebovich, I., Ludányi, K. & Gulyás, Z., Jan 1 2007, In : Medicinal Chemistry. 3, 1, p. 101-106 6 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Perinatal alcohol exposure enhances nocistatin levels in adulthood

Tekes, K., Hantos, M., Gyenge, M. & Csaba, G., Jun 1 2007, In : Addiction Biology. 12, 2, p. 173-175 3 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)