• 1949 Citations
  • 20 h-Index
1973 …2020

Research output per year

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Research Output

  • 1949 Citations
  • 20 h-Index
  • 119 Article
  • 11 Review article
  • 2 Comment/debate
  • 1 Editorial
2020

NCX activity generates spontaneous Ca2+ oscillations in the astrocytic leaflet microdomain

Héja, L. & Kardos, J., Mar 2020, In : Cell Calcium. 86, 102137.

Research output: Contribution to journalArticle

Open Access
2019

Connexin 43 differentially regulates epileptiform activity in models of convulsive and non-convulsive epilepsies

Vincze, R., Péter, M., Szabó, Z., Kardos, J., Héja, L. & Kovács, Z., Apr 12 2019, In : Frontiers in Cellular Neuroscience. 13, 173.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Feedback adaptation of synaptic excitability via Glu:Na+ symport driven astrocytic GABA and Gln release

Héja, L., Simon, Á., Szabó, Z. & Kardos, J., Dec 15 2019, In : Neuropharmacology. 161, 107629.

Research output: Contribution to journalReview article

1 Citation (Scopus)

Molecular Plasticity of the Nucleus Accumbens Revisited—Astrocytic Waves Shall Rise

Kardos, J., Dobolyi, Á., Szabó, Z., Simon, Á., Lourmet, G., Palkovits, M. & Héja, L., Dec 1 2019, In : Molecular Neurobiology. 56, 12, p. 7950-7965 16 p.

Research output: Contribution to journalReview article

Open Access
2 Citations (Scopus)
2018

Copper signalling: Causes and consequences 06 Biological Sciences 0601 Biochemistry and Cell Biology

Kardos, J., Héja, L., Simon, Á., Jablonkai, I., Kovács, R. & Jemnitz, K., Oct 22 2018, In : Cell Communication and Signaling. 16, 1, 71.

Research output: Contribution to journalReview article

10 Citations (Scopus)
1 Citation (Scopus)
2017

Extensive astrocyte synchronization advances neuronal coupling in slow wave activity in vivo

Szabó, Z., Héja, L., Szalay, G., Kékesi, O., Füredi, A., Szebényi, K., Dobolyi, Á., Orbán, T. I., Kolacsek, O., Tompa, T., Miskolczy, Z., Biczók, L., Rózsa, B., Sarkadi, B. & Kardos, J., Dec 1 2017, In : Scientific reports. 7, 1, 6018.

Research output: Contribution to journalArticle

16 Citations (Scopus)

The nature of early astroglial protection—Fast activation and signaling

Kardos, J., Héja, L., Jemnitz, K., Kovács, R. & Palkóvits, M., Jun 1 2017, In : Progress in Neurobiology. 153, p. 86-99 14 p.

Research output: Contribution to journalReview article

9 Citations (Scopus)
2016

Astrocyte sodium signaling and the regulation of neurotransmission

Kirischuk, S., Héja, L., Kardos, J. & Billups, B., Oct 1 2016, In : Glia. 64, 10, p. 1655-1666 12 p.

Research output: Contribution to journalReview article

32 Citations (Scopus)

Framing Neuro-Glia Coupling in Antiepileptic Drug Design

Kardos, J., Szabó, Z. & Héja, L., Feb 11 2016, In : Journal of Medicinal Chemistry. 59, 3, p. 777-787 11 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Straightforward and effective synthesis of γ-aminobutyric acid transporter subtype 2-selective acyl-substituted azaspiro[4.5]decanes

Ma, X., Lubin, H., Ioja, E., Kékesi, O., Simon, Á., Apáti, Á., Orbán, T. I., Héja, L., Kardos, J. & Markó, I. E., Jan 15 2016, In : Bioorganic and Medicinal Chemistry Letters. 26, 2, p. 417-423 7 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2015

Appearance of fast astrocytic component in voltage-sensitive dye imaging of neural activity

Pál, I., Kardos, J., Dobolyi, Á. & Héja, L., Jun 5 2015, In : Molecular brain. 8, 1, 35.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Bilayer Charge Reversal and Modification of Lipid Organization by Dendrimers as Observed by Sum-Frequency Vibrational Spectroscopy

Keszthelyi, T., Holló, G., Nyitrai, G., Kardos, J. & Héja, L., Jul 21 2015, In : Langmuir. 31, 28, p. 7815-7825 11 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2 Citations (Scopus)

How membrane proteins work giving autonomous traverse pathways?

Kardos, J. & Héja, L., Dec 1 2015, In : Structural Chemistry. 26, 5-6, p. 1405-1410 6 p.

Research output: Contribution to journalReview article

3 Citations (Scopus)

Recurrent seizure-like events are associated with coupled astroglial synchronization

Kékesi, O., Ioja, E., Szabó, Z., Kardos, J. & Héja, L., Jun 18 2015, In : Frontiers in Cellular Neuroscience. 9, JUNE, 215.

Research output: Contribution to journalArticle

15 Citations (Scopus)

The janus facet of nanomaterials

Kardos, J., Jemnitz, K., Jablonkai, I., Bóta, A., Varga, Z., Visy, J. & Héja, L., Jan 1 2015, In : BioMed research international. 2015, 317184.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2014
3 Citations (Scopus)
2013

Neuronal and Astroglial Correlates Underlying Spatiotemporal Intrinsic Optical Signal in the Rat Hippocampal Slice

Pál, I., Nyitrai, G., Kardos, J. & Héja, L., Mar 1 2013, In : PloS one. 8, 3, e57694.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Polyamidoamine dendrimer impairs mitochondrial oxidation in brain tissue

Nyitrai, G., Héja, L., Jablonkai, I., Pál, I., Visy, J. & Kardos, J., Apr 4 2013, In : Journal of Nanobiotechnology. 11, 1, 9.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Sodium selective ion channel formation in living cell membranes by polyamidoamine dendrimer

Nyitrai, G., Keszthelyi, T., Bóta, A., Simon, Á., Toke, O., Horváth, G., Pál, I., Kardos, J. & Héja, L., May 9 2013, In : Biochimica et Biophysica Acta - Biomembranes. 1828, 8, p. 1873-1880 8 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)
2012

Assessing toxicity of polyamidoamine dendrimers by neuronal signaling functions

Nyitrai, G., Kékesi, O., Pál, I., Keglevich, P., Csíki, Z., Fügedi, P., Simon, Á., Fitos, I., Németh, K., Visy, J., Tárkányi, G. & Kardos, J., Sep 1 2012, In : Nanotoxicology. 6, 6, p. 576-586 11 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Astrocytes convert network excitation to tonic inhibition of neurons

Héja, L., Nyitrai, G., Kékesi, O., Dobolyi, Á., Szabó, P., Fiáth, R., Ulbert, I., Pál-Szenthe, B., Palkovits, M. & Kardos, J., Mar 15 2012, In : BMC Biology. 10, 26.

Research output: Contribution to journalArticle

89 Citations (Scopus)
2011
8 Citations (Scopus)

Calcium signals in the nucleus accumbens: Activation of astrocytes by ATP and succinate

Molnár, T., Dobolyi, Á., Nyitrai, G., Barabás, P., Héja, L., Emri, Z., Palkovits, M. & Kardos, J., Oct 3 2011, In : BMC neuroscience. 12, 57.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Uridine function in the central nervous system

Dobolyi, A., Juhász, G., Kovács, Z. & Kardos, J., Apr 25 2011, In : Current topics in medicinal chemistry. 11, 8, p. 1058-1067 10 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)
2010
10 Citations (Scopus)

Glutamate uptake shapes low-[Mg2+] induced epileptiform activity in juvenile rat hippocampal slices

Nyitrai, G., Lasztóczi, B. & Kardos, J., Jan 14 2010, In : Brain research. 1309, p. 172-178 7 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2009

Endogenous nitric oxide is a key promoting factor for initiation of seizure-like events in hippocampal and entorhinal cortex slices

Kovács, R., Rabanus, A., Otáhal, J., Patzak, A., Kardos, J., Albus, K., Heinemann, U. & Kann, O., Jul 1 2009, In : Journal of Neuroscience. 29, 26, p. 8565-8577 13 p.

Research output: Contribution to journalArticle

63 Citations (Scopus)

Glutamate uptake triggers transporter-mediated GABA release from astrocytes

Héja, L., Barabás, P., Nyitrai, G., Kékesi, K. A., Lasztóczi, B., Töke, O., Tárkányi, G., Madsen, K., Schousboe, A., Dobolyi, Á., Palkovits, M. & Kardos, J., Sep 24 2009, In : PloS one. 4, 9, e7153.

Research output: Contribution to journalArticle

73 Citations (Scopus)

Substrate-Na+ complex formation: Coupling mechanism for γ-aminobutyrate symporters

Palló, A., Simon, Á., Bencsura, Á., Héja, L. & Kardos, J., Jul 24 2009, In : Biochemical and biophysical research communications. 385, 2, p. 210-214 5 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Synchronization of GABAergic inputs to CA3 pyramidal cells precedes seizure-like event onset in juvenile rat hippocampal slices

Lasztóczi, B., Nyitrai, G., Héja, L. & Kardos, J., Oct 1 2009, In : Journal of Neurophysiology. 102, 4, p. 2538-2553 16 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)
2008

Cyclothiazide binding to the GABAA receptor

Szárics, É., Simon, Á., Visy, J., Simon-Trompler, E., Banka, Z., Héja, L., Hársing, L. G., Blaskó, G. & Kardos, J., Jul 4 2008, In : Neuroscience Letters. 439, 1, p. 66-69 4 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Emerging the role of the structure of brain membrane targets recognizing glutamate

Simon, Á., Bencsura, Á., Palló, A., Héja, L. & Kardos, J., Mar 1 2008, In : Current drug discovery technologies. 5, 1, p. 70-74 5 p.

Research output: Contribution to journalReview article

1 Citation (Scopus)

Validation of high-affinity binding sites for succinic acid through distinguishable binding of gamma-hydroxybutyric acid receptor-specific NCS 382 antipodes

Molnár, T., Visy, J., Simon, Á., Moldvai, I., Temesvári-Major, E., Dörnyei, G., Fekete, E. K. & Kardos, J., Dec 1 2008, In : Bioorganic and Medicinal Chemistry Letters. 18, 23, p. 6290-6292 3 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

γ-Hydroxybutyrate binds to the synaptic site recognizing succinate monocarboxylate: A new hypothesis on astrocyte-neuron interaction via the protonation of succinate

Molnár, T., Barabás, P., Héja, L., Fekete, E. K., Lasztóczi, B., Szabó, P., Nyitrai, G., Simon-Trompler, E., Hajós, F., Palkovits, M. & Kardos, J., May 15 2008, In : Journal of Neuroscience Research. 86, 7, p. 1566-1576 11 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)
2007

Characterization of specific succinate binding site in brain synaptic membranes.

Molnár, T., Fekete, E. K., Kardos, J. & Palkovits, M., Mar 30 2007, In : Ideggyógyászati szemle. 60, 3-4, p. 201-204 4 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Comparison of the binding modes of TT-232 in somatostatin receptors type 1 and 4

Simon, Á., Kéri, G. & Kardos, J., Aug 20 2007, In : Journal of Molecular Structure: THEOCHEM. 816, 1-3, p. 73-76 4 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Dimerization of (+)-lysergic acid esters

Moldvai, I., Gács-Baitz, E., Termesvári-Major, E., Russo, L., Pápai, I., Rissanen, K., Szárics, É., Kardos, J. & Szántay, C., May 1 2007, In : Heterocycles. 71, 5, p. 1075-1094 20 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Major human γ-aminobutyrate transporter: In silico prediction of substrate efficacy

Palló, A., Bencsura, Á., Héja, L., Beke, T., Perczel, A., Kardos, J. & Simon, Á., Dec 28 2007, In : Biochemical and Biophysical Research Communications. 364, 4, p. 952-958 7 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)
2006

Ca2+ ion accumulation precedes formation of O•-2. in isolated brain mitochondria

Szárics, É., Kovács, R., Hajós, F. & Kardos, J., Nov 1 2006, In : Neuroreport. 17, 17, p. 1767-1771 5 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Cyclothiazide prolongs low [Mg2+]-induced seizure-like events

Lasztóczi, B. & Kardos, J., Dec 1 2006, In : Journal of Neurophysiology. 96, 6, p. 3538-3544 7 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Editorial

Kardos, J., May 1 2006, In : Current topics in medicinal chemistry. 6, 10, p. 927-928 2 p.

Research output: Contribution to journalEditorial

15 Citations (Scopus)
11 Citations (Scopus)

Role of GABA and Glu plasma membrane transporters in the interplay of inhibitory and excitatory neurotransmission

Héja, L., Karacs, K. & Kardos, J., May 1 2006, In : Current topics in medicinal chemistry. 6, 10, p. 989-995 7 p.

Research output: Contribution to journalReview article

19 Citations (Scopus)

Structural determinants of phosphodiesterase 6 response on binding catalytic site inhibitors

Simon, Á., Barabás, P. & Kardos, J., Aug 1 2006, In : Neurochemistry international. 49, 3, p. 215-222 8 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
8 Citations (Scopus)

Target structure-based modeling of the glutamate transporter pharmacophore

Simon, Á., Bencsura, Á. & Kardos, J., Jul 10 2006, In : Letters in Drug Design and Discovery. 3, 5, p. 293-297 5 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2005

Mitochondrial calcium ion and membrane potential transients follow the pattern of epileptiform discharges in hippocampal slice cultures

Kovács, R., Kardos, J., Heinemann, U. & Kann, O., Apr 27 2005, In : Journal of Neuroscience. 25, 17, p. 4260-4269 10 p.

Research output: Contribution to journalArticle

71 Citations (Scopus)