• 1676 Citations
  • 25 h-Index
1973 …2018

Research output per year

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Research Output

  • 1676 Citations
  • 25 h-Index
  • 103 Article
  • 3 Review article
  • 2 Conference article
  • 1 Editorial
2018

Dissimilar flexibility of aα and β subunits of human adult hemoglobin influences the protein dynamics and its alteration induced by allosteric effectors

Schay, G., Kaposi, A., Smeller, L., Szigeti, K., Fidy, J. & Herenyi, L., Mar 1 2018, In : PLoS One. 13, 3, e0194994.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2016

Without Binding ATP, Human Rad51 Does Not Form Helical Filaments on ssDNA

Schay, G., Borka, B., Kernya, L., Bulyáki, É., Kardos, J., Fekete, M. & Fidy, J., Mar 17 2016, In : Journal of Physical Chemistry B. 120, 9, p. 2165-2178 14 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2013

Role of domain interactions in the collective motion of phosphoglycerate kinase

Schay, G., Herényi, L., Fidy, J. & Osváth, S., Feb 5 2013, In : Biophysical journal. 104, 3, p. 677-682 6 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2012

Comparison of binding ability and location of two mesoporphyrin derivatives in liposomes explored with conventional and site-selective fluorescence spectroscopy

Veres, D., Böcskei-Antal, B., Voszka, I., Módos, K., Csík, G., Kaposi, A. D., Fidy, J. & Herenyi, L., Aug 16 2012, In : Journal of Physical Chemistry B. 116, 32, p. 9644-9652 9 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Microtubule assembly-derived by dimerization of TPPP/p25. Evaluation of thermodynamic parameters for multiple equilibrium system from ITC data

Oláh, J., Zotter, Á., Hlavanda, E., Szunyogh, S., Orosz, F., Szigeti, K., Fidy, J. & Ovádi, J., Jul 1 2012, In : Biochimica et Biophysica Acta - General Subjects. 1820, 7, p. 785-794 10 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
2011

Ligand chirality effects on the dynamics of human 3-phosphoglycerate kinase: Comparison between D- and L-nucleotides

Palmai, Z., Perahia, D., Lionne, C., Fidy, J., Balog, E. & Chaloin, L., Jul 2011, In : Archives of Biochemistry and Biophysics. 511, 1-2, p. 88-100 13 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Millisecond time-scale protein dynamics exists prior to the activation of the bulk solvent matrix

Schay, G., Herényi, L., Kellermayer, M., Módos, K., Yonetani, T. & Fidy, J., May 19 2011, In : Journal of Physical Chemistry B. 115, 19, p. 5707-5715 9 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Zn 2+-induced rearrangement of the disordered TPPP/p25 affects its microtubule assembly and GTPase activity

Zotter, Á., Oláh, J., Hlavanda, E., Bodor, A., Perczel, A., Szigeti, K., Fidy, J. & Ovádi, J., Nov 8 2011, In : Biochemistry. 50, 44, p. 9568-9578 11 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)
2010

Recovery of functional enzyme from amyloid fibrils

Agócs, G., Solymosi, K., Varga, A., Módos, K., Kellermayer, M., Závodszky, P., Fidy, J. & Osváth, S., Mar 1 2010, In : FEBS letters. 584, 6, p. 1139-1142 4 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2009

Location of mesoporphyrin in liposomes determined by site-selective fluorescence spectroscopy

Herenyi, L., Veres, D., Békási, S., Voszka, I., Modos, K., Csík, G., Kaposi, Á. D. & Fidy, J., May 28 2009, In : Journal of Physical Chemistry B. 113, 21, p. 7716-7724 9 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Mechanism of lysophosphatidic acid-induced amyloid fibril formation of β2-microglobulin in vitro under physiological conditions

Pál-Gábor, H., Gombos, L., Micsonai, A., Kovács, E., Petrik, É., Kovács, J., Gráf, L., Fidy, J., Naiki, H., Goto, Y., Liliom, K. & Kardos, J., Jun 23 2009, In : Biochemistry. 48, 24, p. 5689-5699 11 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Substrate binding modifies the hinge bending characteristics of human 3-phosphoglycerate kinase: A molecular dynamics study

Palmai, Z., Chaloin, L., Lionne, C., Fidy, J., Perahia, D. & Balog, E., Nov 1 2009, In : Proteins: Structure, Function and Bioinformatics. 77, 2, p. 319-329 11 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)
2008

Interaction of antagonists with calmodulin: Insights from molecular dynamics simulations

Kövesi, I., Menyhárd, D. K., Laberge, M. & Fidy, J., Jun 12 2008, In : Journal of Medicinal Chemistry. 51, 11, p. 3081-3093 13 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Methylene substitution at the α-β bridging position within the phosphate chain of dUDP profoundly perturbs ligand accommodation into the dUTPase active site

Kovári, J., Barabás, O., Varga, B., Békési, A., Tölgyesi, F., Fidy, J., Nagy, J. & Vértessy, B. G., Apr 1 2008, In : Proteins: Structure, Function and Genetics. 71, 1, p. 308-319 12 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

Structure and dynamics of the antifungal molecules Syringotoxin-B and Syringopeptin-25A from molecular dynamics simulation

Mátyus, E., Blaskó, K., Fidy, J. & Tieleman, D. P., Apr 1 2008, In : European Biophysics Journal. 37, 4, p. 495-502 8 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

The structure of horseradish peroxidase C characterized as a molten globule state after Ca2+ depletion

Szigeti, K., Smeller, L., Osváth, S., Majer, Z. & Fidy, J., Dec 1 2008, In : Biochimica et Biophysica Acta - Proteins and Proteomics. 1784, 12, p. 1965-1974 10 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2007

Active site closure facilitates juxtaposition of reactant atoms for initiation of catalysis by human dUTPase

Varga, B., Barabás, O., Kovári, J., Tóth, J., Hunyadi-Gulyás, É., Klement, É., Medzihradszky, K. F., Tölgyesi, F., Fidy, J. & Vértessy, B. G., Oct 2 2007, In : FEBS letters. 581, 24, p. 4783-4788 6 p.

Research output: Contribution to journalArticle

48 Citations (Scopus)
10 Citations (Scopus)
21 Citations (Scopus)
2006

Allosteric effectors influence the tetramer stability of both R- and T-states of hemoglobin A

Schay, G., Smeller, L., Tsuneshige, A., Yonetani, T. & Fidy, J., Sep 8 2006, In : Journal of Biological Chemistry. 281, 36, p. 25972-25983 12 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Domain interactions direct misfolding and amyloid formation of yeast phosphoglycerate kinase

Osváth, S., Jäckel, M., Agócs, G., Závodszky, P., Köhler, G. & Fidy, J., Mar 1 2006, In : Proteins: Structure, Function and Genetics. 62, 4, p. 909-917 9 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Hierarchic finite level energy landscape model: To describe the refolding kinetics of phosphoglycerate kinase

Osváth, S., Herényi, L., Závodszky, P., Fidy, J. & Köhler, G., Aug 25 2006, In : Journal of Biological Chemistry. 281, 34, p. 24375-24380 6 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)
5 Citations (Scopus)

Normal mode analysis of the horseradish peroxidase collective motions: Correlation with spectroscopically observed heme distortions

Laberge, M., Kovesi, I., Yonetani, T. & Fidy, J., Jul 1 2006, In : Biopolymers. 82, 4, p. 425-429 5 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Role of domain interactions during the amyloid formation of yeast phosphoglycerate kinase

Agócs, G., Jäckel, M., Fidy, J. & Osváth, S., Dec 1 2006, In : Acta Biologica Szegediensis. 50, 1-2, p. 45-48 4 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Structural investigation of syringomycin-E using molecular dynamics simulation and NMR

Mátyus, E., Monticelli, L., Kövér, K. E., Xu, Z., Blaskó, K., Fidy, J. & Tieleman, D. P., Aug 1 2006, In : European Biophysics Journal. 35, 6, p. 459-467 9 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2005

Asymmetric effect of domain interactions on the kinetics of folding in yeast phosphoglycerate kinase

Osváth, S., Köhler, G., Závodszky, P. & Fidy, J., Jun 1 2005, In : Protein Science. 14, 6, p. 1609-1616 8 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Heat perturbation of bovine eye lens α-crystallin probed by covalently attached ratiometric fluorescent dye 4′-diethylamino-3- hydroxyflavone

Avilov, S. V., Bode, C., Tolgyesi, F. G., Klymchenko, A. S., Fidy, J. & Demchenko, A. P., Aug 15 2005, In : Biopolymers. 78, 6, p. 340-348 9 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Modeling Protein-Lipid Interactions: Recent Advances

Laberge, M., Sugár, I. P. & Fidy, J., Dec 1 2005, In : Advances in Planar Lipid Bilayers and Liposomes. 2, C, p. 187-235 49 p.

Research output: Contribution to journalArticle

R-state hemoglobin bound to heterotropic effectors: Models of the DPG, IHP and RSR13 binding sites

Laberge, M., Kövesi, I., Yonetani, T. & Fidy, J., Jan 31 2005, In : FEBS letters. 579, 3, p. 627-632 6 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)
17 Citations (Scopus)
2004

Aging dynamics in globular proteins: Summary and analysis of experimental results and simulation by a modified trap model

Herenyi, L., Szigeti, K., Fidy, J., Temesvari, T., Schlichter, J. & Friedrich, J., Feb 1 2004, In : European Biophysics Journal. 33, 1, p. 68-75 8 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Hg2+ reacts with different components of the NADPH:protochlorophyllide oxidoreductase macrodomains

Solymosi, K., Lenti, K., Myśliwa-Kurdziel, B., Fidy, J., Strzałka, K. & Böddi, B., May 2004, In : Plant Biology. 6, 3, p. 358-368 11 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Maximum-entropy decomposition of fluorescence correlation spectroscopy data: Application to liposome-human serum albumin association

Módos, K., Galántai, R., Bárdos-Nagy, I., Wachsmuth, M., Tóth, K., Fidy, J. & Langowski, J., Feb 1 2004, In : European Biophysics Journal. 33, 1, p. 59-67 9 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Pressure activation of the chaperone function of small heat shock proteins.

Tölgyesi, E., Böde, C. S., Smelleri, L., Kim, D. R., Kim, K. K., Heremans, K. & Fidy, J., Jun 2004, In : Cellular and molecular biology (Noisy-le-Grand, France). 50, 4, p. 361-369 9 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
9 Citations (Scopus)

The Charge Transfer Band in Horseradish Peroxidase Correlates with Heme In-Plane Distortions Induced by Calcium Removal

Laberge, M., Szigeti, K. & Fidy, J., May 1 2004, In : Biopolymers. 74, 1-2, p. 41-45 5 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)
2003
12 Citations (Scopus)

Chaperone-like activity of α-crystallin is enhanced by high-pressure treatment

Böde, C., Tölgyesi, F. G., Smeller, L., Heremans, K., Avilov, S. V. & Fidy, J., Mar 15 2003, In : Biochemical Journal. 370, 3, p. 859-866 8 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Effect of trehalose on the nonbond associative interactions between small unilamellar vesicles and human serum albumin and on the aging process

Bárdos-Nagy, I., Galántai, R., Laberge, M. & Fidy, J., Jan 7 2003, In : Langmuir. 19, 1, p. 146-153 8 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)
27 Citations (Scopus)

Hsp90 inhibition accelerates cell lysis: Anti-Hsp90 ribozyme reveals a complex mechanism of Hsp90 inhibitors involving both superoxide- and Hsp90-dependent events

Sreedhar, A. S., Mihály, K., Pató, B., Schnaider, T., Steták, A., Kis-Petik, K., Fidy, J., Simonics, T., Maráz, A. & Csermely, P., Sep 12 2003, In : Journal of Biological Chemistry. 278, 37, p. 35231-35240 10 p.

Research output: Contribution to journalArticle

73 Citations (Scopus)

Normal coordinate structural decomposition of the heme distortions of hemoglobin in various quaternary states and bound to allosteric effectors

Laberge, M., Yonetani, T. & Fidy, J., Dec 1 2003, In : Molecular Diversity. 7, 1, p. 15-23 9 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Resonance Raman spectroscopy study of change of iron spin state in horseradish peroxidase C induced by removal of calcium

Huang, Q., Laberge, M., Szigeti, K., Fidy, J. & Schweitzer-Stenner, R., Jul 22 2003, In : Biopolymers - Biospectroscopy Section. 72, 4, p. 241-248 8 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Structural disorder of native horseradish peroxidase C probed by resonance Raman and low-temperature optical absorption spectroscopy

Huang, Q., Szigeti, K., Fidy, J. & Schweitzer-Stenner, R., Mar 27 2003, In : Journal of Physical Chemistry B. 107, 12, p. 2822-2830 9 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

The endogenous calcium ions of horseradish peroxidase C are required to maintain the functional nonplanarity of the heme

Laberge, M., Huang, Q., Schweitzer-Stenner, R. & Fidy, J., Apr 1 2003, In : Biophysical journal. 84, 4, p. 2542-2552 11 p.

Research output: Contribution to journalArticle

Open Access
40 Citations (Scopus)
2002
6 Citations (Scopus)

Aggregation and gel formation of proteins after combined pressuretemperature treatment

Smeller, L., Meersman, F., Fidy, J. & Heremans, K., Dec 1 2002, In : Progress in Biotechnology. 19, C, p. 95-100 6 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)