• 1939 Citations
  • 21 h-Index
19952018

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

Filter
Article
2017

Impact of CT-apelin and NT-proBNP on identifying non-responders to cardiac resynchronization therapy

Kosztin, A., Széplaki, G., Kovács, A., Földes, G., Szokodi, I., Vivien Nagy, K., Kutyifa, V., Fórizs, É., Végh, E. M., Gellér, L., Becker, D., Aradi, D. & Merkely, B., May 19 2017, In : Biomarkers. 22, 3-4, p. 279-286 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2016

Characterization of apela, a novel endogenous ligand of apelin receptor, in the adult heart

Perjés, Á., Kilpiö, T., Ulvila, J., Magga, J., Alakoski, T., Szabó, Z., Vainio, L., Halmetoja, E., Vuolteenaho, O., Petäjä-Repo, U., Szokodi, I. & Kerkelä, R., Jan 1 2016, In : Basic Research in Cardiology. 111, 1, p. 1-12 12 p., 2.

Research output: Contribution to journalArticle

30 Citations (Scopus)
2014

Apelin increases cardiac contractility via protein kinase Cε- And extracellular signal-regulated kinase-dependent mechanisms

Perjés, Á., Skoumal, R., Tenhunen, O., Kónyi, A., Simon, M., Horváth, I. G., Kerkelä, R., Ruskoaho, H. & Szokodi, I., Apr 2 2014, In : PloS one. 9, 4, e93473.

Research output: Contribution to journalArticle

53 Citations (Scopus)

P38α regulates SERCA2a function

Kaikkonen, L., Magga, J., Ronkainen, V. P., Koivisto, E., Perjes, Á., Chuprun, J. K., Vinge, L. E., Kilpiö, T., Aro, J., Ulvila, J., Alakoski, T., Bibb, J. A., Szokodi, I., Koch, W. J., Ruskoaho, H. & Kerkelä, R., Feb 1 2014, In : Journal of Molecular and Cellular Cardiology. 67, p. 86-93 8 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Prognostic value of N-terminal natriuretic peptides in systemic sclerosis: A single centre study

Költo, G., Vuolteenaho, O., Szokodi, I., Faludi, R., Tornyos, A., Ruskoaho, H., Minier, T., Czirják, L. & Komócsi, A., Jan 1 2014, In : Clinical and experimental rheumatology. 32, p. S75-S81

Research output: Contribution to journalArticle

9 Citations (Scopus)
2013

Regulation of cardiac melusin gene expression by hypertrophic stimuli in the rat

Aro, J., Tokola, H., Ronkainen, V. P., Koivisto, E., Tenhunen, O., Ilves, M., Szokodi, I., Ruskoaho, H. & Rysä, J., Mar 1 2013, In : Acta Physiologica. 207, 3, p. 470-484 15 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2012

Neuronostatin, a novel peptide encoded by somatostatin gene, regulates cardiac contractile function and cardiomyocyte survival

Vainio, L., Perjes, A., Ryti, N., Magga, J., Alakoski, T., Serpi, R., Kaikkonen, L., Piuhola, J., Szokodi, I., Ruskoaho, H. & Kerkelä, R., Feb 10 2012, In : Journal of Biological Chemistry. 287, 7, p. 4572-4580 9 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)
2011

Parthenolide inhibits STAT3 signaling and attenuates angiotensin II-induced left ventricular hypertrophy via modulation of fibroblast activity

Skoumal, R., Tóth, M., Serpi, R., Rysä, J., Leskinen, H., Ulvila, J., Saiho, T., Aro, J., Ruskoaho, H., Szokodi, I. & Kerkelä, R., Apr 1 2011, In : Journal of Molecular and Cellular Cardiology. 50, 4, p. 634-641 8 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Role of reactive oxygen species in the regulation of cardiac contractility

Kubin, A. M., Skoumal, R., Tavi, P., Kónyi, A., Perjés, Á., Leskinen, H., Ruskoaho, H. & Szokodi, I., May 1 2011, In : Journal of Molecular and Cellular Cardiology. 50, 5, p. 884-893 10 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)
2010

A novel p38 MAPK target dyxin is rapidly induced by mechanical load in the heart

Luosujrvi, H., Aro, J., Tokola, H., Leskinen, H., Tenhunen, O., Skoumal, R., Szokodi, I., Ruskoaho, H. & Rys, J., Mar 8 2010, In : Blood pressure. 19, 1, p. 54-63 10 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Prolactin-releasing peptide regulates cardiac contractility

Kónyi, A., Skoumal, R., Kubin, A. M., Füredi, G., Perjés, Á., Farkasfalvi, K., Sárszegi, Z., Horkay, F., Horváth, I. G., Tóth, M., Ruskoaho, H. & Szokodi, I., Jan 8 2010, In : Regulatory Peptides. 159, 1-3, p. 9-13 5 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2008

Adaptive or maladaptive response to adenoviral adrenomedullin gene transfer is context-dependent in the heart

Leskinen, H., Rauma-Pinola, T., Szokodi, I., Kerkelä, R., Pikkarainen, S., Uusimaa, P., Hautala, T., Vuolteenaho, O. & Ruskoaho, H., Aug 1 2008, In : Journal of Gene Medicine. 10, 8, p. 867-877 11 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Functionally opposing roles of extracellular signal-regulated kinase 1/2 and p38 mitogen-activated protein kinase in the regulation of cardiac contractility

Szokodi, I., Kerkelä, R., Kubin, A. M., Sármán, B., Pikkarainen, S., Kónyi, A., Horváth, I. G., Papp, L., Tóth, M., Skoumal, R. & Ruskoaho, H., Nov 14 2008, In : Circulation. 118, 16, p. 1651-1658 8 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)
2007

Direct effects of apelin on cardiomyocyte contractility and electrophysiology

Farkasfalvi, K., Stagg, M. A., Coppen, S. R., Siedlecka, U., Lee, J., Soppa, G. K., Marczin, N., Szokodi, I., Yacoub, M. H. & Terracciano, C. M. N., Jun 15 2007, In : Biochemical and biophysical research communications. 357, 4, p. 889-895 7 p.

Research output: Contribution to journalArticle

105 Citations (Scopus)
6 Citations (Scopus)

Involvement of endogenous ouabain-like compound in the cardiac hypertrophic process in vivo

Skoumal, R., Szokodi, I., Aro, J., Földes, G., Göoz, M., Seres, L., Sármán, B., Lakó-Futó, Z., Papp, L., Vuolteenaho, O., Leppäluoto, J., deChâtel, R., Ruskoaho, H. & Tóth, M., Mar 13 2007, In : Life Sciences. 80, 14, p. 1303-1310 8 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Nuclear factor-κB signaling contributes to severe, but not moderate, angiotensin II-induced left ventricular remodeling

Sármán, B., Skoumal, R., Leskinen, H., Rysä, J., Ilves, M., Soini, Y., Tuukkanen, J., Pikkarainen, S., Lakó-Futó, Z., Sármán, B., Papp, L., DeChâtel, R., Tóth, M., Ruskoaho, H. & Szokodi, I., Sep 1 2007, In : Journal of hypertension. 25, 9, p. 1927-1939 13 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)
2005

Posttranscriptional activation of BNP gene expression in response to increased left ventricular wall stress: Role of calcineurin and PKC

Tenhunen, O., Szokodi, I. & Ruskoaho, H., Jun 30 2005, In : Regulatory Peptides. 128, 3, p. 187-196 10 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2004

Ghrelin induces vasoconstriction in the rat coronary vasculature without altering cardiac peptide secretion

Pemberton, C. J., Tokola, H., Bagi, Z., Koller, A., Pöntinen, J., Ola, A., Vuolteenaho, O., Szokodi, I. & Ruskoaho, H., Oct 1 2004, In : American Journal of Physiology - Heart and Circulatory Physiology. 287, 4 56-4, p. H1522-H1529

Research output: Contribution to journalArticle

54 Citations (Scopus)

Mitogen-activated protein kinases p38 and ERK 1/2 mediate the wall stress-induced activation of GATA-4 binding in adult heart

Tenhunen, O., Sármán, B., Kerkelä, R., Szokodi, I., Papp, L., Tóth, M. & Ruskoaho, H., Jun 4 2004, In : Journal of Biological Chemistry. 279, 23, p. 24852-24860 9 p.

Research output: Contribution to journalArticle

75 Citations (Scopus)
2003

Circulating and cardiac levels of apelin, the novel ligand of the orphan receptor APJ, in patients with heart failure

Földes, G., Horkay, F., Szokodi, I., Vuolteenaho, O., Ilves, M., Lindstedt, K. A., Mäyränpää, M., Sármán, B., Seres, L., Skoumal, R., Lakó-Futó, Z., DeChâtel, R., Ruskoaho, H. & Tóth, M., Aug 29 2003, In : Biochemical and biophysical research communications. 308, 3, p. 480-485 6 p.

Research output: Contribution to journalArticle

197 Citations (Scopus)

Dual role of endothelin-1 via ETA and ETB receptors in regulation of cardiac contractile function in mice

Piuhola, J., Mäkinen, M., Szokodi, I. & Ruskoaho, H., Jul 1 2003, In : American Journal of Physiology - Heart and Circulatory Physiology. 285, 1 54-1, p. H112-H118

Research output: Contribution to journalArticle

31 Citations (Scopus)

Endothelin-1 contributes to the Frank-Starling response in hypertrophic rat hearts

Piuhola, J., Szokodi, I., Kinnunen, P., Ilves, M., DeChâtel, R., Vuolteenaho, O. & Ruskoaho, H., Jan 1 2003, In : Hypertension. 41, 1, p. 93-98 6 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

Evidence for a Functional Role of Angiotensin II Type 2 Receptor in the Cardiac Hypertrophic Process in Vivo in the Rat Heart

Lakó-Futó, Z., Szokodi, I., Sármán, B., Földes, G., Tokola, H., Ilves, M., Leskinen, H., Vuolteenaho, O., Skoumal, R., DeChâtel, R., Ruskoaho, H. & Tóth, M., Nov 11 2003, In : Circulation. 108, 19, p. 2414-2422 9 p.

Research output: Contribution to journalArticle

41 Citations (Scopus)
2002

Apelin, the novel endogenous ligand of the orphan receptor APJ, regulates cardiac contractility

Szokodi, I., Tavi, P., Földes, G., Voutilainen-Myllylä, S., Ilves, M., Tokola, H., Pikkarainen, S., Piuhola, J., Rysä, J., Tóth, M. & Ruskoaho, H., Sep 6 2002, In : Circulation research. 91, 5, p. 434-440 7 p.

Research output: Contribution to journalArticle

452 Citations (Scopus)

Direct left ventricular wall stretch activates GATA4 binding in perfused rat heart: Involvement of autocrine/paracrine pathways

Hautala, N., Tenhunen, O., Szokodi, I. & Ruskoaho, H., Feb 5 2002, In : Pflugers Archiv European Journal of Physiology. 443, 3, p. 362-369 8 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)

Posttranscriptional control of BNP gene expression in angiotensin II-induced hypertension

Suo, M., Hautala, N., Földes, G., Szokodi, I., Tóth, M., Leskinen, H., Uusimaa, P., Vuolteenaho, O., Nemer, M. & Ruskoaho, H., Apr 6 2002, In : Hypertension. 39, 3, p. 803-808 6 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)
2001

AM reverses pressor response to ET-1 independently of NO in rat coronary circulation

Kinnunen, P., Piuhola, J., Ruskoaho, H. & Szokodi, I., Oct 1 2001, In : American Journal of Physiology - Heart and Circulatory Physiology. 281, 3 50-3, p. H1178-H1183

Research output: Contribution to journalArticle

8 Citations (Scopus)

Endothelin-1-independent and angiotensin II-independent induction of adrenomedullin gene expression

Romppanen, H., Puhakka, J., Földes, G., Szokodi, I., Vuolteenaho, O., Tokola, H., Tóth, M. & Ruskoaho, H., Jan 1 2001, In : Hypertension. 37, 1, p. 84-90 7 p.

Research output: Contribution to journalArticle

Open Access
19 Citations (Scopus)

Factors derived from adrenals are required for activation of cardiac gene expression in angiotensin II-induced hypertension

Földes, G., Suo, M., Szokodi, I., Lakó-Futó, Z., Dechâtel, R., Vuolteenaho, O., Huttunen, P., Ruskoaho, H. & Tóth, M., Jan 1 2001, In : Endocrinology. 142, 10, p. 4256-4263 8 p.

Research output: Contribution to journalArticle

Open Access
17 Citations (Scopus)
2000

Enhanced accumulation of pericardial fluid ferritin in patients with coronary artery disease

Selmeci, L., Antal, M., Horkay, F., Merkely, B., Szokodi, I., Bíró, L., Székely, M., Jobbágy, J., Szépvölgyi, J. & Tóth, M., Mar 22 2000, In : Coronary Artery Disease. 11, 1, p. 53-56 4 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Impact of NO on ET-1- and AM-induced inotropic responses: Potentiation by combined administration

Kinnunen, P., Szokodi, I., Nicholls, M. G. & Ruskoaho, H., Sep 20 2000, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 279, 2 48-2, p. R569-R575

Research output: Contribution to journalArticle

19 Citations (Scopus)
1998

Bradycardia increases the arrhythmogenic effect of endothelin

Tóth, M., Solti, F., Merkely, B., Kékesi, V., Szokodi, I., Horkay, F. & Juhász-Nagy, A., Jan 1 1998, In : Journal of cardiovascular pharmacology. 31, SUPPL. 1, p. S431-S433

Research output: Contribution to journalArticle

5 Citations (Scopus)

Characterization of canine pericardial fluid endothelin-1 levels

Szokodi, I., Horkay, F., Kiss, P., Selmeci, L., Horváth, I., Vuolteenaho, O., Ruskoaho, H., Juhász-Nagy, A. & Tóth, M., Jan 1 1998, In : Journal of cardiovascular pharmacology. 31, SUPPL. 1, p. S399-S400

Research output: Contribution to journalArticle

10 Citations (Scopus)

Electrophysiological effects of intrapericardial infusion of endothelin-1

Gellér, L., Merkely, B., Szokodi, I., Szabó, T., Vecsey, T., Juhász-Nagy, A., Tóth, M. & Horkay, F., Jan 1 1998, In : PACE - Pacing and Clinical Electrophysiology. 21, 1 II, p. 151-156 6 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Endothelin does not interact with angiotensin II in the coronary vascular bed of anesthetized dogs

Kiss, P., Horváth, I., Szokodi, I., Tóth, P., Kékesi, V., Juhász-Nagy, A. & Tóth, M., Jan 1 1998, In : Journal of cardiovascular pharmacology. 31, SUPPL. 1, p. S103-S105

Research output: Contribution to journalArticle

3 Citations (Scopus)

Evidence for cAMP-independent mechanisms mediating the effects of adrenomedullin, a new inotropic peptide

Szokodi, I., Kinnunen, P., Tavi, P., Weckström, M., Tóth, M. & Ruskoaho, H., Mar 24 1998, In : Circulation. 97, 11, p. 1062-1070 9 p.

Research output: Contribution to journalArticle

Open Access
179 Citations (Scopus)

High pericardial fluid levels of endothelin are not caused by altered neutral endopeptidase activity in cardiac patients

Turbucz, P., Kiss, P., Horkay, F., Szokodi, I., DeChâtel, R., Selmeci, L., Juhász-Nagy, A., Karádi, I. & Tóth, M., Jan 1 1998, In : Journal of cardiovascular pharmacology. 31, SUPPL. 1, p. S287-S289

Research output: Contribution to journalArticle

5 Citations (Scopus)

Intrapericardial infusion of endothelin-1 induces ventricular arrhythmias in dogs

Szokodi, I., Horkay, F., Merkely, B., Solti, F., Gellér, L., Kiss, P., Selmeci, L., Kékesi, V., Vuolteenaho, O., Ruskoaho, H., Juhász-Nagy, A. & Tóth, M., May 1 1998, In : Cardiovascular research. 38, 2, p. 356-364 9 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)

Potential pathophysiologic role of endothelin-1 in canine pericardial fluid

Horkay, F., Szokodi, I., Merkely, B., Solti, F., Gellér, L., Kiss, P., Selmeci, L., Horváth, I., Kékesi, V., Juhász-Nagy, A. & Tóth, M., Jan 1 1998, In : Journal of cardiovascular pharmacology. 31, SUPPL. 1, p. S401-S402

Research output: Contribution to journalArticle

8 Citations (Scopus)

Verapamil reduces the arrhythmogenic effect of endothelin

Solti, F., Tóth, M., Merkely, B., Kékesi, V., Gellér, L., Szokodi, I., Horkay, F. & Juhász-Nagy, A., Jan 1 1998, In : Journal of cardiovascular pharmacology. 31, SUPPL. 1, p. S386-S387

Research output: Contribution to journalArticle

7 Citations (Scopus)
1997

Adrenomedullin gene expression in the rat heart is stimulated by acute pressure overload: Blunted effect in experimental hypertension

Romppanen, H., Marttila, M., Magga, J., Vuolteenaho, O., Kinnunen, P., Szokodi, I. & Ruskoaho, H., Jun 2 1997, In : Endocrinology. 138, 6, p. 2636-2639 4 p.

Research output: Contribution to journalArticle

66 Citations (Scopus)

Characterization and stimuli for production of pericardial, fluid atrial natriuretic peptide in dogs

Szokodi, I., Horkay, F., Kiss, P., Selmeci, L., Merkely, B., Kékesi, V., Vuolteenaho, O., Leppäluoto, J., Ruskoaho, H., Juhász-Nagy, A. & Tóth, M., Nov 29 1997, In : Life Sciences. 61, 14, p. 1349-1359 11 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Presence of immunoreactive endothelin-1 and atrial natriuretic peptide in human pericardial fluid

Horkay, F., Szokodi, I., Selmeci, L., Merkely, B., Kekesi, V., Vecsey, T., Vuolteenaho, O., Ruskoaho, H., Juhasz-Nagy, A. & Toth, M., Dec 12 1997, In : Life Sciences. 62, 3, p. 267-274 8 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)
1996

A sensitive microplate-based continuous-monitoring (kinetic) assay for serum neutral endopeptidase (EC 3.4.24.11) activity

Selmeci, L., Szokodi, I. & Horvát-Karajz, K., Jan 15 1996, In : Clinica Chimica Acta. 244, 1, p. 111-116 6 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Inotropic effect of adrenomedullin in the isolated perfused rat heart

Szokodi, I., Kinnunen, P. & Ruskoaho, H., Jan 1 1996, In : Acta Physiologica Scandinavica. 156, 2, p. 151-152 2 p.

Research output: Contribution to journalArticle

62 Citations (Scopus)
1995

Human pericardial fluid contains the highest amount of endothelin-1 of all mammalian biologic fluids thus far tested

Horkay, F., Laine, M., Szokodi, I., Leppäluoto, J., Vuolteenaho, O., Ruskoaho, H., Juhász-Nagy, A. & Tóth, M., Jan 1 1995, In : Journal of cardiovascular pharmacology. 26, p. S502-S504

Research output: Contribution to journalArticle

25 Citations (Scopus)
26 Citations (Scopus)