• 712 Citations
  • 15 h-Index
1980 …2006

Research output per year

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Research Output

  • 712 Citations
  • 15 h-Index
  • 55 Article
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Article
2006

Effects of bisphosphonates on prostaglandin E2 and thromboxane B2 production in human whole blood and monocytes stimulated by lipopolysaccharide and A23187

Tuominen, O. M., Ylitalo-Heikkala, R., Vehmas, T. I., Mucha, I., Ylitalo, P. & Riutta, A., Jul 1 2006, In : Methods and Findings in Experimental and Clinical Pharmacology. 28, 6, p. 361-367 7 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)
2004

Revascularization decreases 8-isoprostaglandin F excretion in chronic lower limb ischemia

Rossi, P., Riutta, A., Kuukasjärvi, P., Vehmas, T., Mucha, I. & Salenius, J. P., Aug 1 2004, In : Prostaglandins Leukotrienes and Essential Fatty Acids. 71, 2, p. 97-101 5 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2002

Opposite effects of nicotinic acid and pyridoxine on systemic prostacyclin, thromboxane and leukotriene production in man

Saareks, V., Ylitalo, P., Mucha, I. & Riutta, A., Jul 11 2002, In : Pharmacology and Toxicology. 90, 6, p. 338-342 5 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
2001
4 Citations (Scopus)

Effects of smoking cessation and nicotine substitution on systemic eicosanoid production in man

Saareks, V., Ylitalo, P., Alanko, J., Mucha, I. & Riutta, A., Jan 1 2001, In : Naunyn-Schmiedeberg's Archives of Pharmacology. 363, 5, p. 556-561 6 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)
2000

Clinical pharmacology of eicosanoids, nicotine induced changes in man

Saareks, V., Riutta, A., Alanko, J., Ylitalo, P., Parviainen, M., Mucha, I., Sievi, E. & Vapaatalo, H., Dec 1 2000, In : Journal of Physiology and Pharmacology. 51, 4, p. 631-642 12 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
1999

Amrinone, a phosphodiesterase III inhibitor, and arachidonic acid metabolism in humans

Kerttula, T., Alanko, J., Seppälä, E., Riutta, A., Mucha, I., Sievi, E. & Kaukinen, S., Jan 1 1999, In : Journal of cardiovascular pharmacology. 33, 1, p. 140-143 4 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Exercise enhances vasorelaxation in experimental obesity associated hypertension

Arvola, P., Wu, X., Kähönen, M., Mäkynen, H., Riutta, A., Mucha, I., Solakivi, T., Kainulainen, H. & Pörsti, I., Sep 1 1999, In : Cardiovascular research. 43, 4, p. 992-1002 11 p.

Research output: Contribution to journalArticle

53 Citations (Scopus)

Modulation of arachidonic acid metabolism by phenols: Relation to their structure and antioxidant/prooxidant properties

Alanko, J., Riutta, A., Holm, P., Mucha, I., Vapaatalo, H. & Metsä-Ketelä, T., Jan 1999, In : Free Radical Biology and Medicine. 26, 1-2, p. 193-201 9 p.

Research output: Contribution to journalArticle

96 Citations (Scopus)

Nicotinic acid and pyridoxine modulate arachidonic acid metabolism in vitro and ex vivo in man

Saareks, V., Mucha, I., Sievi, E. & Riutta, A., Jan 1 1999, In : Pharmacology and Toxicology. 84, 6, p. 274-280 7 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Post-partum prolongation of the atrial repolarization in rabbit

Pacher, P., Ungvári, Z., Nánási, P. P., Mucha, I., Kecskeméti, V. & Losonczy, G., Jun 8 1999, In : Acta Physiologica Scandinavica. 166, 1, p. 1-5 5 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
1998

Catechol estrogens as inhibitors of leukotriene synthesis

Alanko, J., Sievi, E., Lähteenmäki, T., Mucha, I., Vapaatalo, H. & Parantainen, J., Jan 1 1998, In : Biochemical Pharmacology. 55, 1, p. 101-104 4 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Nicotine stereoisomers and cotinine stimulate prostaglandin E2 but inhibit thromboxane B2 and leukotriene E4 synthesis in whole blood

Saareks, V., Mucha, I., Sievi, E., Vapaatalo, H. & Riutta, A., Jul 17 1998, In : European Journal of Pharmacology. 353, 1, p. 87-92 6 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)
12 Citations (Scopus)
1997

Experimental fat embolism induces urine 2,3-dinor-6-ketoprostaglandin F(1α) and 11-dehydrothromboxane B2 excretion in pigs

Rautanen, M., Gullichsen, E., Riutta, A., Kuttila, K., Mucha, I., Nelimarkka, O. & Niinikoski, J., Jul 1 1997, In : Critical care medicine. 25, 7, p. 1215-1221 7 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)
8 Citations (Scopus)

Percutaneous translaminal angioplasty increases thromboxane A2 production in claudicants

Rossi, P., Kuukasjärvi, P., Salenius, J. P., Tarkka, M., Kerttula, T., Alanko, J., Mucha, I. & Riutta, A., May 1997, In : Prostaglandins Leukotrienes and Essential Fatty Acids. 56, 5, p. 369-372 4 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Theophylline infusion modulates prostaglandin and leukotriene production in man

Kerttula, T., Kaukinen, S., Seppälä, E., Riutta, A., Mucha, I., Ylitalo, P. & Alanko, J., Dec 1997, In : Prostaglandins Leukotrienes and Essential Fatty Acids. 57, 6, p. 555-560 6 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
1996

Effects of corticotropin-releasing hormone on ACTH, cortisol and 13,14-dihydro-15-keto prostaglandin E2 in patients with diabetes insipidus before and after captopril treatment

Zacharieva, S., Andreeva, M., Orbetzova, M., Wippermann, M., Mucha, I., Andonova, K. & Sheitanova, S., Jun 1996, In : Prostaglandins Leukotrienes and Essential Fatty Acids. 54, 6, p. 433-437 5 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Prostacyclin and thromboxane A2 synthesis are increased in acute lowe limb ischaemia

Rossi, P., Kuukasjärvi, P., Riutta, A., Salenius, J. P., Tarkka, M., Mucha, I., Kerttula, T. & Alanko, J., Dec 1996, In : Prostaglandins Leukotrienes and Essential Fatty Acids. 55, 6, p. 433-436 4 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

The vasoconstrictor effects of L-NAME, a nitric oxide synthase inhibitor, in pregnant rabbits

Losonczy, G., Mucha, I., Müller, V., Kriston, T., Ungvári, Z., Tornóci, L., Rosivall, L. & Venuto, R., Jan 1 1996, In : British journal of pharmacology. 118, 4, p. 1012-1018 7 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
1995

Effect of NO-donors, SIN-1 and GEA 3175 on prostacyclin and cGMP synthesis in cultured rat endothelial cells

Alanko, J., Sievi, E., Lahteenmaki, T., Mucha, I., Riutta, A. & Vapaatalo, H., Jan 1 1995, In : Agents and Actions. 45, SUPPL. I, p. 195-199 5 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Effects of indomethacin and meclofenamate on kallikrein activity and a stable metabolite of prostaglandin E2 in healthy subjects

Orbetzova, M., Zacharieva, S., Angelova-Gateva, P., Mucha, I. & Andonova, K., Mar 1 1995, In : Endocrinology and Metabolism. 2, 1, p. 33-37 5 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Effects of noradrenaline and dopamine infusions on arachidonic acid metabolism in man

Kerttula, T., Kaukinen, S., Riutta, A., Seppälä, E., Mucha, I., Vapaatalo, H. & Alanko, J., Oct 15 1995, In : Thrombosis research. 80, 2, p. 169-178 10 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Endotoxin inhibits glucuronidation in the liver. An effect mediated by intercellular communication

Bánhegyi, G., Mucha, I., Garzó, T., Antoni, F. & Mandl, J., Jan 6 1995, In : Biochemical Pharmacology. 49, 1, p. 65-68 4 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Lack of a specific effect of corticotropin-releasing hormone (CRH) on plasma levels of 13,14-dihydro-15-keto-prostaglandin E2 in normal subjects

Zacharieva, S., Muchá, I., Wippermann, M., Sheitanova, S. & Andonova, K., Jan 1995, In : Prostaglandins, Leukotrienes and Essential Fatty Acids. 52, 1, p. 55-57 3 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Pregnancy enhances the pressor response to thromboxane analogues in rabbits

Losonczy, G., Singh, J. P., Schoenl, M., Mucha, I. & Venuto, R. C., Jan 1 1995, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 269, 3 38-3, p. R720-R725

Research output: Contribution to journalArticle

11 Citations (Scopus)

Smoking cessation and nicotine substitution modulate eicosanoid synthesis ex vivo in man

Riutta, A., Saareks, V., Mucha, I., Alanko, J., Parviainen, M. & Vapaatalo, H., Jul 1995, In : Naunyn-Schmiedeberg's Archives of Pharmacology. 352, 1, p. 102-107 6 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)
1994

Effects of Trolox C and SIN-1 on arachidonic acid metabolism and on cyclic GMP formation in leukocytes

Riutta, A., Alanko, J., Mucha, I. & Vapaatalo, H., Sep 12 1994, In : European Journal of Pharmacology. 262, 3, p. 217-222 6 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Selective Solid-Phase Extraction of Urinary 2,3-Dinor-6-ketoprostaglandin F for Determination with Radioimmunoassay

Riutta, A., Nurmi, E., Weber, C., Hansson, G., Vapaatalo, H. & Mucha, I., Aug 1 1994, In : Analytical Biochemistry. 220, 2, p. 351-359 9 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)
1993

Indomethacin and meclofenamate do not alter ACTH and cortisol responses to corticotropin-releasing hormone (CRH) in normal subjects.

Zacharieva, S., Wippermann, M., Muchá, I., Andonova, K. & Jankova, G., 1993, In : Clinical physiology and biochemistry. 10, 1, p. 28-32 5 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Modulation of arachidonic acid metabolism by phenols: Relation to positions of hydroxyl groups and peroxyl radical scavenging properties

Alanko, J., Riutta, A., Mucha, I., Vapaatalo, H. & Metsä-Ketelä, T., Jan 1993, In : Free Radical Biology and Medicine. 14, 1, p. 19-25 7 p.

Research output: Contribution to journalArticle

46 Citations (Scopus)

Nicotine and cotinine modulate eicosanoid production in human leukocytes and platelet rich plasma

Saareks, V., Riutta, A., Mucha, I., Alanko, J. & Vapaatalo, H., Dec 1 1993, In : European Journal of Pharmacology: Environmental Toxicology and. 248, 4, p. 345-349 5 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Potentiation of reduced uteroplacental perfusion pressure hypertension in pregnant rabbits

Losonczy, G. & Mucha, I., Jan 1 1993, In : Hypertension in Pregnancy. 12, 3, p. 475-485 11 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

The effect of pregnancy on the response to the TxA2/PGH2 analogue U- 46619 in rabbits

Losonczy, G., Mucha, I., DiPirro, J., Sweeney, J., Brown, G., Brentjens, J. & Venuto, R., 1993, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 265, 4 34-4, p. R772-R780

Research output: Contribution to journalArticle

9 Citations (Scopus)
1992

Adrenaline stimulates thromboxane and inhibits leukotriene synthesis in man

Alanko, J., Riutta, A., Mucha, I., Kerttula, T., Kaukinen, S., Vapaatalo, H., Metsa-Ketela, T. & Seppala, E., Dec 1 1992, In : Eicosanoids. 5, 3-4, p. 169-175 7 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)
1 Citation (Scopus)

Solid-phase extraction of urinary 11-dehydrothromboxane B2 for reliable determination with radioimmunoassay

Riutta, A., Mucha, I. & Vapaatalo, H., May 1 1992, In : Analytical Biochemistry. 202, 2, p. 299-305 7 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)
1991

Catecholamines decrease leukotriene B4 and increase thromboxane B2 synthesis in A23187-stimulated human whole blood

Alanko, J., Riutta, A., Vapaatalo, H. & Mucha, I., Sep 1991, In : Prostaglandins. 42, 3, p. 279-287 9 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)
8 Citations (Scopus)

Seperation of 125I-labelled derivatives of 5-hydroxy-6,8,11,14-ecosatetraenoic acid

Mucha, I., Paluska-Ferencz, I. & Tóth, G., 1991, In : Journal of Chromatography A. 543, C, p. 307-314 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
1990

Changes of arterial prostaglandin e2 during haemodialysis

Losonczy, G. Y., Walter, J., Mucha, I. & Taraba, I., Jan 1 1990, In : Nephrology Dialysis Transplantation. 5, 11, p. 937-941 5 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Prostaglandin E2 adn gestational hypotension in rabbits

Mucha, I. & Losonczy, G., Aug 1990, In : Prostaglandins. 40, 2, p. 143-153 11 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
1989

Adsorption chromatographic separation of 125I-labelled derivatives of 3′-azido-3′-deoxythymidine

Mucha, I., Tanacs, B. & Toth, G., 1989, In : Journal of Chromatography A. 478, C, p. 280-283 4 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
8 Citations (Scopus)

Separation of 125I-labelled prostanoid derivatives by reversed-phase high-performance liquid chromatography

Mucha, I. & Tóth, G., 1989, In : Journal of Chromatography A. 483, C, p. 419-426 8 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
1988

cAMP dependent inhibition of thromboxane A2, prostacyclin and PGF synthesis in mouse hepatocytes

Mandl, J., Mucha, I., Bánhegyi, G., Mészáros, G., Faragó, A., Spolarics, Z., Machovich, R., Antoni, F. & Garzó, T., Dec 1988, In : Prostaglandins. 36, 6, p. 761-772 12 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
4 Citations (Scopus)
1987

Inhibitory effect of A 23187 on protein synthesis in isolated murine hepatocytes

Kalapos, M. P., Garzo, T., Banhegyi, G., Mucha, I., Antoni, F. & Mandl, J., Oct 15 1987, In : Acta biochimica et biophysica Hungarica. 22, 1, p. 59-66 8 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Prostanoid synthesis in isolated parenchymal and nonparenchymal mouse liver cells in the presence of arachioonic acid

Spolarics, Z., Mucha, I., Mandl, J., Machovich, R., Bánhegyi, G., Antonio, F. & Garzó, T., Oct 1987, In : Prostaglandins, Leukotrienes and Medicine. 29, 2-3, p. 113-127 15 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)