• 938 Citations
  • 19 h-Index
1975 …2015

Research output per year

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Research Output

  • 938 Citations
  • 19 h-Index
  • 51 Article
  • 2 Review article
  • 1 Comment/debate
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Article
2015

Synthesis and serum protein binding of novel ring-substituted harmine derivatives

Domonkos, C., Zsila, F., Fitos, I., Visy, J., Kassai, R., Bálint, B. & Kotschy, A., Jan 1 2015, In : RSC Advances. 5, 66, p. 53809-53818 10 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
2014
6 Citations (Scopus)
2013

Fatty acid modulated human serum albumin binding of the β-carboline alkaloids norharmane and harmane

Domonkos, C., Fitos, I., Visy, J. & Zsila, F., Dec 2 2013, In : Molecular Pharmaceutics. 10, 12, p. 4706-4716 11 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)
2012

Assessing toxicity of polyamidoamine dendrimers by neuronal signaling functions

Nyitrai, G., Kékesi, O., Pál, I., Keglevich, P., Csíki, Z., Fügedi, P., Simon, Á., Fitos, I., Németh, K., Visy, J., Tárkányi, G. & Kardos, J., Sep 1 2012, In : Nanotoxicology. 6, 6, p. 576-586 11 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
7 Citations (Scopus)
13 Citations (Scopus)
2008

Organogold complexes probe a large β-barrel cavity for human serum α1-acid glycoprotein

Zsila, F., Bikádi, Z., Hazai, E., Simon, Á., Fitos, I. & Mády, G., Jul 1 2008, In : Biochimica et Biophysica Acta - Proteins and Proteomics. 1784, 7-8, p. 1106-1114 9 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Selective plasma protein binding of antimalarial drugs to α1-acid glycoprotein

Zsila, F., Visy, J., Mády, G. & Fitos, I., Apr 1 2008, In : Bioorganic and Medicinal Chemistry. 16, 7, p. 3759-3772 14 p.

Research output: Contribution to journalArticle

41 Citations (Scopus)
2007
16 Citations (Scopus)
2006

Chromatographic analysis of allosteric effects between ibuprofen and benzodiazepines on human serum albumin

Chen, J., Fitos, I. & Hage, D. S., Jan 9 2006, In : Chirality. 18, 1, p. 24-36 13 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Selective binding of coumarin enantiomers to human α1-acid glycoprotein genetic variants

Hazai, E., Visy, J., Fitos, I., Bikádi, Z. & Simonyi, M., Mar 15 2006, In : Bioorganic and Medicinal Chemistry. 14, 6, p. 1959-1965 7 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)
47 Citations (Scopus)
2004

In vitro plasma protein binding and aqueous aggregation behavior of astaxanthin dilysinate tetrahydrochloride

Zsila, F., Fitos, I., Bikádi, Z., Simonyi, M., Jackson, H. L. & Lockwood, S. F., Nov 1 2004, In : Bioorganic and Medicinal Chemistry Letters. 14, 21, p. 5357-5366 10 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)
36 Citations (Scopus)
2002

Enantioselective plasma protein binding of bimoclomol

Visy, J., Fitos, I., Mády, G., Ürge, L., Krajcsi, P. & Simonyi, M., Aug 3 2002, In : Chirality. 14, 8, p. 638-642 5 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)
39 Citations (Scopus)

Stereoselective kinetics of warfarin binding to human serum albumin: Effect of an allosteric interaction

Fitos, I., Visy, J. & Kardos, J., May 20 2002, In : Chirality. 14, 5, p. 442-448 7 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)
1999

Stereoselective allosteric binding interaction on human serum albumin between ibuprofen and lorazepam acetate

Fitos, I., Visy, J., Simonyi, M. & Hermansson, J., Feb 3 1999, In : Chirality. 11, 2, p. 115-120 6 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)
1998

Covalent protein binding of a minor deramciclane metabolite in dog plasma

Visy, J., Fitos, I., Mády, G., Simonyi, M., Ludányi, K., Szunyog, J. & Klebovich, I., Dec 1 1998, In : Pharmacy and Pharmacology Communications. 4, 12, p. 587-590 4 p.

Research output: Contribution to journalArticle

1996

Plasma protein binding of deramciclane in different species

Visy, J., Fitos, I., Mady, G., Simonyi, M. & Klebovich, I., Dec 1 1996, In : Pharmaceutical Sciences. 2, 7, p. 315-318 4 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
1995

Separation of enantiomers of benzodiazepines on the Chiral-AGP column

Fitos, I., Visy, J., Simonyi, M. & Hermansson, J., Aug 18 1995, In : Journal of Chromatography A. 709, 2, p. 265-273 9 p.

Research output: Contribution to journalArticle

41 Citations (Scopus)

Stereoselective binding of benzodiazepines and related compounds on calmodulin‐sepharose

Fitos, I., Visy, J., Kardos, J. & Simonyi, M., 1995, In : Chirality. 7, 2, p. 69-73 5 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
1993
6 Citations (Scopus)
15 Citations (Scopus)
1992
37 Citations (Scopus)
14 Citations (Scopus)
1991

Binding of vinca alkaloid analogues to human serum albumin and to α1-acid glycoprotein

Fitos, I., Visy, J. & Simonyi, M., Feb 1 1991, In : Biochemical Pharmacology. 41, 3, p. 377-383 7 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)
1990

Demonstration of stereoselective disposition of warfarin enantiomers by whole-body autoradiography

Szinai, I., Simonyi, M., Fitos, I., Tegyey, Z. & Magyar, A., Apr 1 1990, In : European Journal of Drug Metabolism and Pharmacokinetics. 15, 2, p. 103-107 5 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
12 Citations (Scopus)
1989

Inverse stereoselectivity in the binding of acenocoumarol to human serum albumin and to α1-acid glycoprotein

Fitos, I., Visy, J., Magyar, A., Kajtár, J. & Simonyi, M., Jul 15 1989, In : Biochemical Pharmacology. 38, 14, p. 2259-2262 4 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)
1988
12 Citations (Scopus)
1986

Binding of 3‐Alkyl‐1,4‐benzodiazepin‐2‐one Stereoisomers to Human Serum Albumin

Fitos, I., Simonyi, M., Tegyey, Z., Kajtár, M. & Ötvös, L., 1986, In : Archiv der Pharmazie. 319, 8, p. 744-749 6 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
67 Citations (Scopus)

Investigation on the binding of tryptophan enantiomers to human serum albumin.

Fitos, I. & Simonyi, M., Dec 1 1986, In : Acta biochimica et biophysica Hungarica. 21, 3, p. 237-245 9 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Stereoselective binding of 3-acetoxy-, and 3-hydroxy-1,4-benzodiazepine-2-ones to human serum albumin. Selective allosteric interaction with warfarin enantiomers

Fitos, I., Tegyey, Z., Simonyi, M., Sjöholm, I., Larsson, T. & Lagercrantz, C., Jan 15 1986, In : Biochemical Pharmacology. 35, 2, p. 263-269 7 p.

Research output: Contribution to journalArticle

56 Citations (Scopus)
1983

Resolution by affinity chromatography: stereoselective binding of racemic oxazepam esters to human serum albumin

Fitos, I., Simonyi, M., Tegyey, Z., Ötvös, L., Kajtár, J. & Kajtár, M., 1983, In : Journal of Chromatography A. 259, C, p. 494-498 5 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Stereoselective binding of 4,5-dihydrodiazepam to human serum albumin

Fitos, I. & Simonyi, M., Jun 1 1983, In : Experientia. 39, 6, p. 591-592 2 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
21 Citations (Scopus)
1982

Application of ultrafiltration and CD spectroscopy for studying stereoselective binding of racemic ligands

Simonyi, M., Fitos, I., Kajtár, J. & Kajtár, M., Dec 15 1982, In : Biochemical and biophysical research communications. 109, 3, p. 851-857 7 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
1980

Stationary ultrafiltration: A radio-tracer technique for studying stereoselective binding of racemic ligands

Simonyi, M., Fitos, I., Tegyey, Z. & Ötvös, L., Jan 1 1980, In : Topics in Catalysis. 97, 1, p. 1-7 7 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
7 Citations (Scopus)
1979

Binding study of 4-methylumbelliferyl α-D-mannopyranoside to dimeric concanavalin-A under high pressure

Fitos, I., Heremans, K. & Loontiens, F. G., Dec 1 1979, In : Reaction Kinetics and Catalysis Letters. 12, 4, p. 393-397 5 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Kinetic investigation of glutamate dehydrogenase self-association under high pressure

Fitos, I. & Heremans, K., Dec 1 1979, In : Reaction Kinetics and Catalysis Letters. 12, 4, p. 399-403 5 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
1978
3 Citations (Scopus)
1977
5 Citations (Scopus)
1976
1 Citation (Scopus)
1975

Kinetic deuterium isotope effect and hydrogen bonding

Simonyi, M., Kardos, J., Fitos, I., Kovács, I., Holly, S. & Pospišil, J., 1975, In : Tetrahedron Letters. 16, 8, p. 565-568 4 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
6 Citations (Scopus)