• 1392 Citations
  • 24 h-Index
19962019

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Article
2019

Ninjurin1 regulates striated muscle growth and differentiation

Kny, M., Csályi, K. D., Klaeske, K., Busch, K., Meyer, A. M., Merks, A. M., Darm, K., Dworatzek, E., Fliegner, D., Baczko, I., Regitz-Zagrosek, V., Butter, C., Luft, F. C., Panáková, D. & Fielitz, J., May 2019, In : PloS one. 14, 5, e0216987.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Sex differences in the aging human heart: Decreased sirtuins, proinflammatory shift and reduced anti-oxidative defense

de Arellano, M. L. B., Pozdniakova, S., Kühl, A. A., Baczko, I., Ladilov, Y. & Regitz-Zagrosek, V., Apr 15 2019, In : Aging. 11, 7, p. 1918-1933 16 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2018

Comparison of the effects of IK,ACh, IKr, and INa block in conscious dogs with atrial fibrillation and on action potentials in remodeled atrial trabeculae

Juhász, V., Hornyik, T., Benák, A., Nagy, N., Husti, Z., Pap, R., Sághy, L., Virág, L., Varró, A. & Baczkó, I., Jan 1 2018, In : Canadian journal of physiology and pharmacology. 96, 1, p. 18-25 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Identification of optimal reference genes for transcriptomic analyses in normal and diseased human heart

Molina, C. E., Jacquet, E., Ponien, P., Muñoz-Guijosa, C., Baczkó, I., Maier, L. S., Donzeau-Gouge, P., Dobrev, D., Fischmeister, R. & Garnier, A., Feb 1 2018, In : Cardiovascular research. 114, 2, p. 247-258 12 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Localization and functional consequences of a direct interaction between TRIOBP-1 and hERG proteins in the heart

Jones, D. K., Johnson, A. C., Roti, E. C. R., Liu, F., Uelmen, R., Ayers, R. A., Baczkó, I., Tester, D. J., Ackerman, M. J., Trudeau, M. C. & Robertson, G. A., Mar 1 2018, In : Journal of Cell Science. 131, 6, jcs206730.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Long-term endurance training-induced cardiac adaptation in new rabbit and dog animal models of the human athlete's heart

Polyák, A., Kui, P., Morvay, N., Leprán, I., Ágoston, G., Varga, A., Nagy, N., Baczkó, I., Farkas, A., Papp, J. G., Varró, A. & Farkas, A. S., Jan 1 2018, In : Reviews in cardiovascular medicine. 19, 4, p. 135-142 8 p.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Nicotinamide riboside preserves cardiac function in a mouse model of dilated cardiomyopathy

Diguet, N., Trammell, S. A. J., Tannous, C., Deloux, R., Piquereau, J., Mougenot, N., Gouge, A., Gressette, M., Manoury, B., Blanc, J., Breton, M., Decaux, J. F., Lavery, G. G., Baczkó, I., Zoll, J., Garnier, A., Li, Z., Brenner, C. & Mericskay, M., Jan 1 2018, In : Circulation. 137, 21, p. 2256-2273 18 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)
2017

Genomic upregulation of cardiac Cav1.2α and NCX1 by estrogen in women

Papp, R., Bett, G. C. L., Lis, A., Rasmusson, R. L., Baczkó, I., Varró, A. & Salama, G., Aug 14 2017, In : Biology of sex differences. 8, 1, 26.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Increased short-term beat-to-beat QT interval variability in patients with impaired glucose tolerance

Orosz, A., Baczkó, I., Nyiraty, S., Körei, A. E., Putz, Z., Takács, R., Nemes, A., Várkonyi, T., Balogh, L., Ábrahám, G., Kempler, P., Papp, J., Varró, A. & Lengyel, C., Jun 13 2017, In : Frontiers in Endocrinology. 8, JUN, 129.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Inverse remodelling of K2P 3.1 K+ channel expression and action potential duration in left ventricular dysfunction and atrial fibrillation: Implications for patient-specific antiarrhythmic drug therapy

Schmidt, C., Wiedmann, F., Zhou, X. B., Heijman, J., Voigt, N., Ratte, A., Lang, S., Kallenberger, S. M., Campana, C., Weymann, A., De Simone, R., Szabo, G., Ruhparwar, A., Kallenbach, K., Karck, M., Ehrlich, J. R., Baczkó, I., Borggrefe, M., Ravens, U., Dobrev, D. & 2 others, Katus, H. A. & Thomas, D., Jun 7 2017, In : European heart journal. 38, 22, p. 1764-1774 11 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)
2016

A novel transgenic rabbit model with reduced repolarization reserve: Long QT syndrome caused by a dominant-negative mutation of the KCNE1 gene

Major, P., Baczkó, I., Hiripi, L., Odening, K. E., Juhász, V., Kohajda, Z., Horváth, A., Seprényi, G., Kovács, M., Virág, L., Jost, N., Prorok, J., Ördög, B., Doleschall, Z., Nattel, S., Varró, A. & Bõsze, Z., Jun 1 2016, In : British journal of pharmacology. 173, 12, p. 2046-2061 16 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Effects of aging on cardiac extracellular matrix in men and women

Dworatzek, E., Baczkó, I. & Kararigas, G., Jan 1 2016, In : Proteomics - Clinical Applications. 10, 1, p. 84-91 8 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Modulation of vascular reactivity by novel synthetic benzopyran analogues in rat aortas

Petrus, A., Sturza, A., Utu, D., Duicu, O., Bedreag, O., Kiss, L., Baczkó, I., Muntean, D. & Jost, N., 2016, In : Revista de Chimie. 67, 5, p. 908-910 3 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
8 Citations (Scopus)

Sarcolemmal Ca2+-entry through L-type Ca2+ channels controls the profile of Ca2+-activated Cl- current in canine ventricular myocytes

Horváth, B., Váczi, K., Hegyi, B., Gönczi, M., Dienes, B., Kistamás, K., Bányász, T., Magyar, J., Baczkó, I., Varró, A., Seprényi, G., Csernoch, L., Nánási, P. & Szentandrássy, N., Aug 1 2016, In : Journal of Molecular and Cellular Cardiology. 97, p. 125-139 15 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

The potential impact of new generation transgenic methods on creating rabbit models of cardiac diseases

Bösze, Z., Major, P., Baczkó, I., Odening, K. E., Bodrogi, L., Hiripi, L. & Varró, A., Jan 14 2016, (Accepted/In press) In : Progress in Biophysics and Molecular Biology.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2015

Atp-sensitive potassium channel modulators and cardiac arrhythmias: An update

Muntean, D. M., Kiss, L., Jost, N. & Baczkó, I., Jan 1 2015, In : Current pharmaceutical design. 21, 8, p. 1091-1102 12 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Combined inhibition of key potassium currents has different effects on cardiac repolarization reserve and arrhythmia susceptibility in dogs and rabbits

Husti, Z., Tábori, K., Juhász, V., Hornyik, T., Varró, A. & Baczkó, I., Mar 11 2015, In : Canadian journal of physiology and pharmacology. 93, 7, p. 535-544 10 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Future perspectives in the pharmacological treatment of atrial fibrillation and ventricular arrhythmias in heart failure

Baczkó, I., Leprán, I., Kiss, L., Muntean, D. M. & Light, P. E., Jan 1 2015, In : Current pharmaceutical design. 21, 8, p. 1011-1029 19 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Increased short-term beat-to-beat variability of QT interval in patients with acromegaly

Orosz, A., Csajbók, É., Czékus, C., Gavallér, H., Magony, S., Valkusz, Z., Várkonyi, T. T., Nemes, A., Baczkó, I., Forster, T., Wittmann, T., Papp, J. G., Varró, A. & Lengyel, C., Apr 27 2015, In : PloS one. 10, 4, e0125639.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2 Citations (Scopus)

Modulation of mitochondrial respiratory function and ROS production by novel benzopyran analogues

Petruş, A., Duicu, O. M., Sturza, A., Noveanu, L., Kiss, L., Dănilă, M., Baczkó, I., Muntean, D. M. & Jost, N., Apr 15 2015, In : Canadian journal of physiology and pharmacology. 93, 9, p. 811-818 8 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Resveratrol and derivatives for the treatment of atrial fibrillation

Baczkó, I. & Light, P. E., Jan 1 2015, In : Annals of the New York Academy of Sciences. 1348, 1, p. 68-74 7 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
4 Citations (Scopus)

Upregulation of K2P 3.1 K + Current Causes Action Potential Shortening in Patients with Chronic Atrial Fibrillation

Schmidt, C., Wiedmann, F., Voigt, N., Zhou, X. B., Heijman, J., Lang, S., Albert, V., Kallenberger, S., Ruhparwar, A., Szabó, G., Kallenbach, K., Karck, M., Borggrefe, M., Biliczki, P., Ehrlich, J. R., Baczkó, I., Lugenbiel, P., Schweizer, P. A., Donner, B. C., Katus, H. A. & 2 others, Dobrev, D. & Thomas, D., Jul 14 2015, In : Circulation. 132, 2, p. 82-92 11 p.

Research output: Contribution to journalArticle

79 Citations (Scopus)
2014

Characterization of a novel multifunctional resveratrol derivative for the treatment of atrial fibrillation

Baczko, I., Liknes, D., Yang, W., Hamming, K. C., Searle, G., Jaeger, K., Husti, Z., Juhasz, V., Klausz, G., Pap, R., Saghy, L., Varro, A., Dolinsky, V., Wang, S., Rauniyar, V., Hall, D., Dyck, J. R. B. & Light, P. E., Jan 1 2014, In : British journal of pharmacology. 171, 1, p. 92-106 15 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Coxsackie and adenovirus receptor is a modifier of cardiac conduction and arrhythmia vulnerability in the setting of myocardial ischemia

Marsman, R. F. J., Bezzina, C. R., Freiberg, F., Verkerk, A. O., Adriaens, M. E., Podliesna, S., Chen, C., Purfürst, B., Spallek, B., Koopmann, T. T., Baczko, I., Dos Remedios, C. G., George, A. L., Bishopric, N. H., Lodder, E. M., De Bakker, J. M. T., Fischer, R., Coronel, R., Wilde, A. A. M., Gotthardt, M. & 1 others, Remme, C. A., Feb 18 2014, In : Journal of the American College of Cardiology. 63, 6, p. 549-559 11 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Genome-wide identification of expression Quantitative Trait Loci (eQTLs) in human heart

Koopmann, T. T., Adriaens, M. E., Moerland, P. D., Marsman, R. F., Westerveld, M. L., Lal, S., Zhang, T., Simmons, C. Q., Baczko, I., Dos Remedios, C., Bishopric, N. H., Varro, A., George, A. L., Lodder, E. M. & Bezzina, C. R., May 20 2014, In : PloS one. 9, 5, e97380.

Research output: Contribution to journalArticle

33 Citations (Scopus)

Sex-dependent regulation of fibrosis and inflammation in human left ventricular remodelling under pressure overload

Kararigas, G., Dworatzek, E., Petrov, G., Summer, H., Schulze, T. M., Baczko, I., Knosalla, C., Golz, S., Hetzer, R. & Regitz-Zagrosek, V., Nov 1 2014, In : European journal of heart failure. 16, 11, p. 1160-1167 8 p.

Research output: Contribution to journalArticle

59 Citations (Scopus)
2013

Altered expression of genes for kir ion channels in dilated cardiomyopathy

Szuts, V., Ménesi, D., Varga-Orvos, Z., Zvara, Á., Houshmand, N., Bitay, M., Bogáts, G., Virág, L., Baczkó, I., Szalontai, B., Geramipoor, A., Cotella, D., Wettwer, E., Ravens, U., Deák, F., Puskás, L. G., Papp, J. G., Kiss, I., Varró, A. & Jost, N., Aug 1 2013, In : Canadian journal of physiology and pharmacology. 91, 8, p. 648-656 9 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)
2012

Diclofenac Prolongs Repolarization in Ventricular Muscle with Impaired Repolarization Reserve

Kristóf, A., Husti, Z., Koncz, I., Kohajda, Z., Szél, T., Juhász, V., Biliczki, P., Jost, N., Baczkó, I., Papp, J. G., Varró, A. & Virág, L., Dec 31 2012, In : PloS one. 7, 12, e53255.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Transcriptome characterization of estrogen-treated human myocardium identifies myosin regulatory light chain interacting protein as a sex-specific element influencing contractile function

Kararigas, G., Bito, V., Tinel, H., Becher, E., Baczko, I., Knosalla, C., Albrecht-Kpper, B., Sipido, K. R. & Regitz-Zagrosek, V., Jan 24 2012, In : Journal of the American College of Cardiology. 59, 4, p. 410-417 8 p.

Research output: Contribution to journalArticle

55 Citations (Scopus)
2011

Atrial remodeling and novel pharmacological strategies for antiarrhythmic therapy in atrial fibrillation

Jost, N., Kohajda, Z., Kristóf, A., Kovács, P. P., Husti, Z., Juhász, V., Kiss, L., Varró, A., Virág, L. & Baczkó, I., Aug 1 2011, In : Current medicinal chemistry. 18, 24, p. 3675-3694 20 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Class I/B antiarrhythmic property of ranolazine, a novel antianginal agent, in dog and human cardiac preparations

Szél, T., Koncz, I., Jost, N., Baczkó, I., Husti, Z., Virág, L., Bussek, A., Wettwer, E., Ravens, U., Papp, J. G. & Varró, A., Jul 15 2011, In : European Journal of Pharmacology. 662, 1-3, p. 31-39 9 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Electrophysiological effects of ivabradine in dog and human cardiac preparations: Potential antiarrhythmic actions

Koncz, I., Szél, T., Bitay, M., Cerbai, E., Jaeger, K., Fülöp, F., Jost, N., Virág, L., Orvos, P., Tálosi, L., Kristóf, A., Baczkó, I., Papp, J. G. & Varró, A., Oct 15 2011, In : European Journal of Pharmacology. 668, 3, p. 419-426 8 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)

Increased short-term variability of the qt interval in professional soccer players: Possible implications for arrhythmia prediction

Lengyel, C., Orosz, A., Hegyi, P., Komka, Z., Udvardy, A., Bosnyák, E., Trájer, E., Pavlik, G., Tóth, M., Wittmann, T., Papp, J. G., Varró, A. & Baczkó, I., Apr 25 2011, In : PloS one. 6, 4, e18751.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Sarcolemmal KATP channel modulators and cardiac arrhythmias

Baczkó, I., Husti, Z., Lang, V., Leprán, I. & Light, P. E., Aug 1 2011, In : Current medicinal chemistry. 18, 24, p. 3640-3661 22 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Selective pharmacological inhibition of the pacemaker channel isoforms (HCN1-4) as new possible therapeutical targets

Koncz, I., Szél, T., Jaeger, K., Baczkó, I., Cerbai, E., Romanelli, M. N., Papp, J. G. & Varró, A., Aug 1 2011, In : Current medicinal chemistry. 18, 24, p. 3662-3674 13 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)
2010

Mechanisms of ventricular rate adaptation as a predictor of arrhythmic risk

Pueyo, E., Husti, Z., Hornyik, T., Baczkó, I., Laguna, P., Varró, A. & Rodríguez, B., May 1 2010, In : American Journal of Physiology - Heart and Circulatory Physiology. 298, 5, p. H1577-H1587

Research output: Contribution to journalArticle

58 Citations (Scopus)
2009
27 Citations (Scopus)

Distinct early signaling events resulting from the expression of the PRKAG2 R302Q mutant of AMPK contribute to increased myocardial glycogen

Folmes, K. D., Chan, A. Y. M., Koonen, D. P. Y., Pulinilkunnil, T. C., Baczkó, I., Hunter, B. E., Thorn, S., Allard, M. F., Roberts, R., Gollob, M. H., Light, P. E. & Dyck, J. R. B., Oct 1 2009, In : Circulation: Cardiovascular Genetics. 2, 5, p. 457-466 10 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)
2008

Diastolic calcium is elevated in metabolic recovery of cardiomyocytes expressing elevated levels of the Na+/H+ exchanger

Baczkó, I., Mraiche, F., Light, P. E. & Fliegel, L., Dec 1 2008, In : Canadian journal of physiology and pharmacology. 86, 12, p. 850-859 10 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Inhibition of matrix metalloproteinases prevents peroxynitrite-induced contractile dysfunction in the isolated cardiac myocyte

León, H., Baczkó, I., Sawicki, G., Light, P. E. & Schulz, R., Feb 1 2008, In : British journal of pharmacology. 153, 4, p. 676-683 8 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)
2007
70 Citations (Scopus)
39 Citations (Scopus)
2006

Inhibition of cardiac voltage-gated sodium channels by grape polyphenols

Wallace, C. H. R., Baczkó, I., Jones, L., Fercho, M. & Light, P. E., Nov 3 2006, In : British journal of pharmacology. 149, 6, p. 657-665 9 p.

Research output: Contribution to journalArticle

50 Citations (Scopus)
15 Citations (Scopus)

Metabolic regulation of sodium-calcium exchange by intracellular acyl CoAs

Riedel, M. J., Baczkó, I., Searle, G. J., Webster, N., Fercho, M., Jones, L., Lang, J., Lytton, J., Dyck, J. R. B. & Light, P. E., Oct 4 2006, In : EMBO Journal. 25, 19, p. 4605-4614 10 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)
2005

Plasma membrane KATP channel-mediated cardioprotection involves posthypoxic reductions in calcium overload and contractile dysfunction: Mechanistic insights into cardioplegia

Baczkó, I., Jones, L., McGuigan, C. F., Fox, J. E. M., Gandhi, M., Giles, W. R., Clanachan, A. S. & Light, P. E., Jun 1 2005, In : FASEB Journal. 19, 8, p. 980-982 3 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)
2004
56 Citations (Scopus)