• 1113 Citations
  • 19 h-Index
1987 …2020
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Research Output 1987 2020

  • 1113 Citations
  • 19 h-Index
  • 148 Article
  • 4 Review article
  • 2 Chapter
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Article
2020

Development, validation and application of LC–MS/MS method for quantification of amino acids, kynurenine and serotonin in human plasma

Virág, D., Király, M., Drahos, L., Édes, A. E., Gecse, K., Bagdy, G., Juhász, G., Antal, I., Klebovich, I., Dalmadi Kiss, B. & Ludányi, K., Feb 20 2020, In : Journal of Pharmaceutical and Biomedical Analysis. 180, 113018.

Research output: Contribution to journalArticle

Open Access
Plasma (human)
Kynurenine
Serotonin
Amino Acids
Trifluoroacetic Acid
2019

Physicochemical Profiling of Baicalin Along with the Development and Characterization of Cyclodextrin Inclusion Complexes

Jakab, G., Bogdán, D., Mazák, K., Deme, R., Mucsi, Z., Mándity, I., Noszál, B., Kállai-Szabó, N. & Antal, I., Sep 16 2019, In : AAPS PharmSciTech. 20, 8, 1 p.

Research output: Contribution to journalArticle

Open Access
Cyclodextrins
Solubility
flavone
Drug Delivery Systems
Biological Availability

Skin-on-a-chip device for ex vivo monitoring of transdermal delivery of drugs—design, fabrication, and testing

Lukács, B., Bajza, Á., Kocsis, D., Csorba, A., Antal, I., Iván, K., Laki, A. J. & Erdő, F., Sep 2019, In : Pharmaceutics. 11, 9, 445.

Research output: Contribution to journalArticle

Open Access
Equipment and Supplies
Drug Compounding
Skin
Microfluidics
Drug Costs
1 Citation (Scopus)

Validation of an in vitro-in vivo assay system for evaluation of transdermal delivery of caffeine

Farner, F., Bors, L., Bajza, Á., Karvaly, G., Antal, I. & Erdő, F., Jan 1 2019, In : Drug Delivery Letters. 9, 1, p. 15-20 6 p.

Research output: Contribution to journalArticle

Caffeine
Assays
Skin
Microdialysis
Pharmaceutical Preparations
2018

A transzmukozalis hatoanyagbevitel biofarmaciai es formulalasi szempontjai

Translated title of the contribution: Biophar-maceutical and formulations aspects of transmucosal drug deliveryEdit, P. Z., Dora, F., Livia, B., Emese, B. & Antal, I., Jan 1 2018, In : Acta pharmaceutica Hungarica. 88, 4, p. 227-235 9 p.

Research output: Contribution to journalArticle

Mucus
Drug Delivery Systems
Pharmaceutical Preparations
Architectural Accessibility
Gastrointestinal Tract
1 Citation (Scopus)

Baicalin is a substrate of OATP2B1 and OATP1B3

Kalapos-Kovács, B., Juhász, V., Temesszentandrási-Ambrus, C., Magda, B., Szabó, P., Antal, I., Klebovich, I. & Krajcsi, P., Aug 1 2018, In : Phytotherapy Research. 32, 8, p. 1647-1650 4 p.

Research output: Contribution to journalArticle

baicalin
2 Citations (Scopus)

Optimization of quality attributes and atomic force microscopy imaging of reconstituted nanodroplets in baicalin loaded self-nanoemulsifying formulations

Jakab, G., Fülöp, V., Bozó, T., Balogh, E., Kellermayer, M. & Antal, I., Dec 1 2018, In : Pharmaceutics. 10, 4, 275.

Research output: Contribution to journalArticle

Atomic Force Microscopy
Drug Delivery Systems
Solubility
baicalin
Water
1 Citation (Scopus)

Study on process parameters and optimization of microencapsulation based on phase separation

Lengyel, M., Balogh, E., Szerőczei, D., Dobó-Nagy, C., Pápay, Z., Stömmer, V., Klebovich, I. & Antal, I., Sep 15 2018, In : European Journal of Pharmaceutical Sciences. 122, p. 273-280 8 p.

Research output: Contribution to journalArticle

Drug Compounding
Microspheres
Surface-Active Agents
Drug Carriers
Freeze Drying
1 Citation (Scopus)

Study on the dissolution improvement of albendazole using reconstitutable dry nanosuspension formulation

Fülöp, V., Jakab, G., Bozó, T., Tóth, B., Endrésik, D., Balogh, E., Kellermayer, M. & Antal, I., Oct 15 2018, In : European Journal of Pharmaceutical Sciences. 123, p. 70-78 9 p.

Research output: Contribution to journalArticle

Albendazole
Rumen
Powders
Solubility
Hydrodynamics
2017
13 Citations (Scopus)

Development and characterization of the voriconazole loaded lipid-based nanoparticles

Füredi, P., Pápay, Z. E., Kovács, K., Kiss, B. D., Ludányi, K., Antal, I. & Klebovich, I., Jan 5 2017, In : Journal of Pharmaceutical and Biomedical Analysis. 132, p. 184-189 6 p.

Research output: Contribution to journalArticle

Nanoparticles
Lipids
Mycoses
Particle Size
Solubility

Önemulgeáló hatóanyag-felszabadító rendszerek, mikroemulziók és nanoemulziók formulálási lehetoségei

Translated title of the contribution: Formulation possibilities of self-emulsifying drug delivery systems, microemulsions and nanoemulsionsGéza, J., Viktor, F., Konrád, S., Debóra, S., Emese, B. & Antal, I., Jan 1 2017, In : Acta Pharmaceutica Hungarica. 87, 1, p. 27-34 8 p.

Research output: Contribution to journalArticle

Drug Delivery Systems
Lipids
Excipients
Biological Availability
Water
2 Citations (Scopus)

Physicochemical analysis in the evaluation of reconstituted dry emulsion tablets

Niczinger, N. A., Kállai-Szabó, B., Lengyel, M., Gordon, P., Klebovich, I. & Antal, I., Feb 5 2017, In : Journal of Pharmaceutical and Biomedical Analysis. 134, p. 86-93 8 p.

Research output: Contribution to journalArticle

Emulsions
Tablets
Oils
Excipients
Nephelometry and Turbidimetry
15 Citations (Scopus)

Study on the Pulmonary Delivery System of Apigenin-Loaded Albumin Nanocarriers with Antioxidant Activity

Pápay, Z. E., Kósa, A., Böddi, B., Merchant, Z., Saleem, I. Y., Zariwala, M. G., Klebovich, I., Somavarapu, S. & Antal, I., Aug 1 2017, In : Journal of Aerosol Medicine and Pulmonary Drug Delivery. 30, 4, p. 274-288 15 p.

Research output: Contribution to journalArticle

Apigenin
Albumins
Antioxidants
Nanoparticles
Lung
3 Citations (Scopus)

Use of antibiotic-impregnated bone grafts in a rabbit osteomyelitis model

Zahar, A., Kocsis, G., Citak, M., Puskás, G., Domahidy, M., Hajdú, M., Antal, I. & Szendrői, M., Jan 1 2017, In : Technology and Health Care. 25, 5, p. 929-938 10 p.

Research output: Contribution to journalArticle

Antibiotics
Osteomyelitis
Grafts
Bone
Anti-Bacterial Agents
2016

A nanogyógyszerek és nanotechnológia f ormulálási vonatkozásai I. Bevezetés, biofarmáciai szempontok

Translated title of the contribution: Formulation aspects of nanopharmaceuticals and nanotechnology I. Introduction, biopharmaceutical aspectsViktor, F., Emese, B., Géza, J. & Antal, I., 2016, In : Acta Pharmaceutica Hungarica. 86, 2, p. 43-52 10 p.

Research output: Contribution to journalArticle

Nanotechnology
Pharmaceutical Preparations
Nanoparticles
Nanomedicine
Biological Availability
1 Citation (Scopus)

Assessment of distribution of pellets in tablets by non-destructive microfocus X-ray imaging and image analysis technique

Csobán, Z., Kállai-Szabó, B., Kállai-Szabó, N., Takács, T., Hurtony, T., Gordon, P., Zelkó, R. & Antal, I., Nov 1 2016, In : Powder Technology. 301, p. 228-233 6 p.

Research output: Contribution to journalArticle

Image analysis
Tablets
Imaging techniques
X rays
Potassium Chloride
1 Citation (Scopus)

Biológiai gyógyszerek analitikai vonatkozásai és tömegspektrometriás vizsgálata

Translated title of the contribution: Analytical aspects of biopharmaceuticals and their study by mass spectrometryDávid, V., Borbála, D. K., Vékey, K., Drahos, L., Antal, I., Klebovich, I. & Ludányi, K., Jan 1 2016, In : Acta Pharmaceutica Hungarica. 86, 4, p. 141-150 10 p.

Research output: Contribution to journalArticle

Mass Spectrometry
Biosimilar Pharmaceuticals
Protein Multimerization
Pharmaceutical Preparations
Post Translational Protein Processing
19 Citations (Scopus)

Comparative evaluation of the effect of cyclodextrins and pH on aqueous solubility of apigenin

Pápay, Z. E., Sebestyén, Z., Ludányi, K., Kállai, N., Balogh, E., Kósa, A., Somavarapu, S., Böddi, B. & Antal, I., Jan 5 2016, In : Journal of Pharmaceutical and Biomedical Analysis. 117, p. 210-216 7 p.

Research output: Contribution to journalArticle

Apigenin
Cyclodextrins
Flavonoids
Solubility
Derivatives
7 Citations (Scopus)

Development and characterization of voriconazole loaded nanoparticles for parenteral delivery

Füredi, P., Kovács, K., Ludányi, K., Antal, I. & Klebovich, I., Aug 20 2016, In : International Journal of Pharmaceutics. 510, 1, p. 159-163 5 p.

Research output: Contribution to journalArticle

Nanoparticles
Pharmaceutical Preparations
Particle Size
Solubility
Albumins
2 Citations (Scopus)

Tömegspektrometria: múlt és jelen

Translated title of the contribution: Mass spectrometry: Past and presentMárton, K., Borbála, D. K., Károly, V., István, A. & Krisztina, L., 2016, In : Acta Pharmaceutica Hungarica. 86, 1, p. 3-11 9 p.

Research output: Contribution to journalArticle

Mass Spectrometry
Technology
Tandem Mass Spectrometry
Molecular Structure
Complex Mixtures

Tömegspektrometria alkalmazása a fehérjék vizsgálatában

Translated title of the contribution: Application of mass spectrometry in proteomicsMárton, K., Borbála, D. K., Drahos, L., Vékey, K., Antal, I. & Ludányi, K., 2016, In : Acta Pharmaceutica Hungarica. 86, 2, p. 61-67 7 p.

Research output: Contribution to journalArticle

Proteomics
Mass Spectrometry
Proteins
Protein Sequence Analysis
Post Translational Protein Processing
2015
2 Citations (Scopus)

Application of droplet size analysis for the determination of the required HLB of lemon oil in O/W emulsion

Niczinger, N. A., Kállai-Szabó, N., Dredán, J., Budai, L., Hajdú, M. & Antal, I., Jan 1 2015, In : Current Pharmaceutical Analysis. 11, 1, p. 11-15 5 p.

Research output: Contribution to journalArticle

Emulsions
Oils
Emulsifying Agents
Water
Polysorbates

Funkcionális élelmiszerek típusai, eloállitási módszerei és minoségbiztosításuk

Translated title of the contribution: Introduction of functional foods-types, manufacturing methods and quality assuranceAnna, B. K., Balázs, H., Antal, I. & Zelkó, R., 2015, In : Acta Pharmaceutica Hungarica. 85, 3, p. 97-110 14 p.

Research output: Contribution to journalArticle

Functional Food
Technology
Prebiotics
Drug Compounding
Food Handling
5 Citations (Scopus)

Improvement of mechanical properties of pellet containing tablets by thermal treatment

Csobán, Z., Kállai-Szabó, B., Kállai-Szabó, N., Sebe, I., Gordon, P. & Antal, I., Dec 30 2015, In : International Journal of Pharmaceutics. 496, 2, p. 489-496 8 p.

Research output: Contribution to journalArticle

Tensile Strength
Tablets
Hot Temperature
Lactose
Caffeine
5 Citations (Scopus)

Microstructural analysis of the fast gelling freeze-dried sodium hyaluronate

Krüger-Szabó, A., Aigner, Z., Balogh, E., Sebe, I., Zelkó, R. & Antal, I., Feb 1 2015, In : Journal of Pharmaceutical and Biomedical Analysis. 104, p. 12-16 5 p.

Research output: Contribution to journalArticle

Hyaluronic Acid
Gels
Positron annihilation
Freeze Drying
Free volume
24 Citations (Scopus)

Multiple ABC Transporters Efflux Baicalin

Kalapos-Kovács, B., Magda, B., Jani, M., Fekete, Z., Szabó, P., Antal, I., Krajcsi, P. & Klebovich, I., Dec 1 2015, In : Phytotherapy Research. 29, 12, p. 1987-1990 4 p.

Research output: Contribution to journalArticle

ATP-Binding Cassette Transporters
Enterocytes
Inhibitory Concentration 50
Hepatocytes
baicalin

The influence of selected excipients on the rheological behaviour of chitosan based ocular pharmaceutical systems

Budai, L., Szabadi, E., Hajdú, M., Budai, M., Klebovich, I. & Antal, I., Apr 15 2015, In : Journal of Physics: Conference Series. 602, 1, 012041.

Research output: Contribution to journalArticle

steam
gels
propylene
glycols
castor oil
2014
2 Citations (Scopus)

Comparative dissolution study of drug and inert isomalt based core material from layered pellets

Kállai-Szabó, N., Luhn, O., Bernard, J., Kállai-Szabó, B., Zelkó, R. & Antal, I., 2014, In : Journal of Pharmaceutical and Biomedical Analysis. 98, p. 339-344 6 p.

Research output: Contribution to journalArticle

Dissolution
Diclofenac
Pharmaceutical Preparations
Refractometry
Coatings
1 Citation (Scopus)

Tracking of the solubility enhancement and drug release stability of melt extrudates containing mebendazole

Kállai-Szabó, B., Sinka, M., Stiedl, B., Sebe, I., Antal, I. & Zelkó, R., Sep 1 2014, In : Journal of Drug Delivery Science and Technology. 24, 5, p. 514-518 5 p.

Research output: Contribution to journalArticle

Mebendazole
Drug Stability
Solubility
Polymers
Plasticizers
2013
4 Citations (Scopus)

Dohányzás-gyógyszer interakciók jelento{combining double acute accent}sége a korszeru{combining double acute accent} gyógyszerkutatásban

Translated title of the contribution: Importance of drug interactions with smoking in modern drug researchSzilvia, L., Bernadett, K. K., Antal, I. & Klebovich, I., 2013, In : Acta Pharmaceutica Hungarica. 83, 4, p. 107-120 14 p.

Research output: Contribution to journalArticle

Drug Interactions
Smoking
Research
Pharmaceutical Preparations
Cytochrome P-450 CYP1A2
17 Citations (Scopus)

Liposomes for topical use: A physico-chemical comparison of vesicles prepared from egg or soy lecithin

Budai, L., Kaszás, N., Gróf, P., Lenti, K., Maghami, K., Antal, I., Klebovich, I., Petrikovics, I. & Budai, M., 2013, In : Scientia Pharmaceutica. 81, 4, p. 1151-1166 16 p.

Research output: Contribution to journalArticle

Lecithins
Liposomes
Ovum
Caffeine
Membrane Fluidity

Multipartikuláris gyógyszerhordozó rendszer formulálása tablettába préselt pelletek alkalmazásával

Translated title of the contribution: Formulation of multiparticular drug delivery systems by compressing pellets into tabletsZsombor, C., Nikolett, K., Ádám, P. & Antal, I., 2013, In : Acta Pharmaceutica Hungarica. 83, 4, p. 134-142 9 p.

Research output: Contribution to journalArticle

Excipients
Drug Delivery Systems
Tablets
Pressure
Therapeutics
7 Citations (Scopus)

Structural elucidation of hyaluronic acid gels after heat sterilisation

Szabó, A., Szabó, B., Balogh, E., Zelkó, R. & Antal, I., 2013, In : Polymer Testing. 32, 8, p. 1322-1325 4 p.

Research output: Contribution to journalArticle

Hyaluronic acid
Hyaluronic Acid
Gels
Hydrogels
Microstructure
4 Citations (Scopus)

Supramolecular elucidation of the quality attributes of microcrystalline cellulose and isomalt composite pellet cores

Antal, I., Kállai, N., Luhn, O., Bernard, J., Nagy, Z. K., Szabó, B., Klebovich, I. & Zelkó, R., Oct 2013, In : Journal of Pharmaceutical and Biomedical Analysis. 84, p. 124-128 5 p.

Research output: Contribution to journalArticle

Composite materials
Sugar Alcohols
Positron annihilation
Tensile Strength
Free volume
2012
2 Citations (Scopus)

Dissolution profile of novel composite pellet cores based on different ratios of microcrystalline cellulose and isomalt

Luhn, O., Kállai, N., Nagy, Z. K., Kovács, K., Fritzsching, B., Klebovich, I. & Antal, I., Aug 2012, In : Journal of Pharmaceutical Sciences. 101, 8, p. 2675-2680 6 p.

Research output: Contribution to journalArticle

Diclofenac
Pharmaceutical Preparations
Osmolar Concentration
Gastrointestinal Tract
Polymers

Hosszú hatóanyag-leadású antibiotikus csontgraftok alkalmazása állatkísérletes osteomyelitis modellben: Másodközlés

Translated title of the contribution: Use of bone grafts impregnated with long acting antibiotic in rabbit osteomyelitis model. Second communicationÁkos, Z., György, K., Béla, L., Gábor, P., Mónika, L., Mária, H. & Antal, I., Jul 2012, In : Magyar Allatorvosok Lapja. 134, 7, p. 417-422 6 p.

Research output: Contribution to journalArticle

osteomyelitis
Osteomyelitis
animal communication
drug delivery systems
Vancomycin

Intraorális gyógyszerformák fejlesztési leheto{combining double acute accent}ségei

Translated title of the contribution: Formulation strategies of intraoral dosage formsNikolett, K., Zita, S., Barnab́as, S., Viktória, S., Antal, I. & Zelkó, R., 2012, In : Acta Pharmaceutica Hungarica. 82, 3, p. 95-103 9 p.

Research output: Contribution to journalArticle

Dosage Forms
Drug Delivery Systems
Deglutition
Patient Compliance
Deglutition Disorders
2 Citations (Scopus)

Módosított hatóanyagleadású intraartikuláris készítmények.

Translated title of the contribution: [Modified release intra-articular drug delivery systems].Szabó, A., Szabó, B., Balogh, E., Zelkó, R. & Antal, I., 2012, In : Acta Pharmaceutica Hungarica. 82, 2, p. 69-74 6 p.

Research output: Contribution to journalArticle

Drug Delivery Systems
Joints
Injections
Hydrogels
Hyaluronic Acid
8 Citations (Scopus)

Natural oils and waxes: studies on stick bases.

Budai, L., Antal, I., Klebovich, I. & Budai, M., Mar 2012, In : Journal of Cosmetic Science. 63, 2, p. 93-101 9 p.

Research output: Contribution to journalArticle

Waxes
Hardness
Oils
Castor Oil
Hot Temperature
8 Citations (Scopus)

Petroselinum crispum kivonatának gyógyszerészeti vonatkozásai és formulálási lehetocombining double acute accentségei

Translated title of the contribution: Pharmaceutical and formulation aspects of Petroselinum crispum extractPápay, Z. E., Kósa, A., Boldizsár, I., Ruszkai, Á., Balogh, E., Klebovich, I. & Antal, I., 2012, In : Acta Pharmaceutica Hungarica. 82, 1, p. 3-14 12 p.

Research output: Contribution to journalArticle

Petroselinum
Apigenin
Drug Compounding
Flavonoids
Spices
2011
3 Citations (Scopus)

A HLB-érték jelentosége a gyó gyszertechnológiában

Translated title of the contribution: Importance of the HLB-value in the drug-technologyNiczinger, N. A., Hajdú, M., Budai, L., Dredán, J. & Antal, I., 2011, In : Acta Pharmaceutica Hungarica. 81, 4, p. 151-163 13 p.

Research output: Contribution to journalArticle

Surface-Active Agents
Technology
Pharmaceutical Preparations
Research
3 Citations (Scopus)

Determination of gentamicin released from orthopedic carrier system by a novel HPLC method

Laki, M., Ludányi, K., Hajdú, M., Zahár, Á., Szendrői, M., Klebovich, I. & Antal, I., Mar 2011, In : Journal of Chromatographic Science. 49, 3, p. 177-181 5 p.

Research output: Contribution to journalArticle

Orthopedics
Gentamicins
Calibration
Ammonia
Pharmaceutical Preparations
8 Citations (Scopus)

Evaluation of the impact of mixing speed on the compressibility and compactibility of paracetamol-isomalt containing granules with factorial design

Sáska, Z., Dredán, J., Luhn, O., Balogh, E., Shafir, G. & Antal, I., Nov 10 2011, In : Powder Technology. 213, 1, p. 132-140 9 p.

Research output: Contribution to journalArticle

Acetaminophen
Compressibility
Tablets
Compaction
Binders
13 Citations (Scopus)

Improved therapeutic entities derived from known generics as an unexplored source of innovative drug products

Stegemann, S., Klebovich, I., Antal, I., Blume, H. H., Magyar, K., Németh, G., Paál, T. L., Stumptner, W., Thaler, G., Van De Putte, A. & Shah, V. P., Nov 20 2011, In : European Journal of Pharmaceutical Sciences. 44, 4, p. 447-454 8 p.

Research output: Contribution to journalArticle

Life Cycle Stages
Pharmaceutical Preparations
Investigational Therapies
Dosage Forms
Drug Industry
11 Citations (Scopus)

New formulation of in situ gelling Metolose-based liquid suppository

Pásztor, E., Makó, Á., Csóka, G., Fenyvesi, Z., Benko, R., Prosszer, M., Marton, S., Antal, I. & Klebovich, I., Jan 2011, In : Drug Development and Industrial Pharmacy. 37, 1, p. 1-7 7 p.

Research output: Contribution to journalArticle

Suppositories
Temperature
Liquids
Gelation
Salts
1 Citation (Scopus)

Reumás megbetegedések kezelése intraartikuláris készítménnyel

Translated title of the contribution: Treatment of rheumatic diseases with intraarticular drug delivery systemsSzabó, A., Zelkó, R. & Antal, I., 2011, In : Acta Pharmaceutica Hungarica. 81, 2, p. 77-86 10 p.

Research output: Contribution to journalArticle

Drug Delivery Systems
Rheumatic Diseases
Joints
Intra-Articular Injections
Hyaluronic Acid
19 Citations (Scopus)

Schizophrenia: Redox regulation and volume neurotransmission

Bókkon, I. & Antal, I., Jun 2011, In : Current Neuropharmacology. 9, 2, p. 289-300 12 p.

Research output: Contribution to journalArticle

Synaptic Transmission
Oxidation-Reduction
Schizophrenia
Dopamine
Neuronal Plasticity
35 Citations (Scopus)

Spontaneous and visible light-induced ultraweak photon emission from rat eyes

Wang, C., Bókkon, I., Dai, J. & Antal, I., Oct 19 2011, In : Brain Research. 1369, p. 1-9 9 p.

Research output: Contribution to journalArticle

Photons
Light
Phosphenes
Noise
Vitreous Body
19 Citations (Scopus)

Visible light induced ocular delayed bioluminescence as a possible origin of negative afterimage

Bókkon, I., Vimal, R. L. P., Wang, C., Dai, J., Salari, V., Grass, F. & Antal, I., May 3 2011, In : Journal of Photochemistry and Photobiology, B: Biology. 103, 2, p. 192-199 8 p.

Research output: Contribution to journalArticle

afterimages
Afterimage
bioluminescence
Photons
Light
2010
2 Citations (Scopus)
High performance liquid chromatography
Ciprofloxacin
Mass spectrometry
Fats
Drug interactions