• 5018 Citations
  • 35 h-Index
19972020

Research output per year

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Research Output

2020

A novel deep intronic SERPING1 variant as a cause of hereditary angioedema due to C1-inhibitor deficiency

Vatsiou, S., Zamanakou, M., Loules, G., Psarros, F., Parsopoulou, F., Csuka, D., Valerieva, A., Staevska, M., Porebski, G., Obtulowicz, K., Magerl, M., Maurer, M., Speletas, M., Farkas, H. & Germenis, A. E., Jan 1 2020, (Accepted/In press) In : Allergology International.

Research output: Contribution to journalArticle

Open Access

Biological therapy in hereditary angioedema: transformation of a rare disease

Longhurst, H. & Farkas, H., May 3 2020, In : Expert Opinion on Biological Therapy. 20, 5, p. 493-501 9 p.

Research output: Contribution to journalReview article

Changes of coagulation parameters during erythema marginatum in patients with hereditary angioedema

Kőhalmi, K. V., Mező, B., Veszeli, N., Benedek, S., Fehér, A., Holdonner, Á., Jesenak, M., Varga, L. & Farkas, H., Apr 2020, In : International Immunopharmacology. 81, 106293.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Evaluation of the efficacy and safety of home treatment with the recombinant human C1-inhibitor in hereditary angioedema resulting from C1-inhibitor deficiency

Andrási, N., Veszeli, N., Holdonner, Á., Temesszentandrási, G., Kőhalmi, K. V., Varga, L. & Farkas, H., Mar 2020, In : International Immunopharmacology. 80, 106216.

Research output: Contribution to journalArticle

Open Access

Hereditary angioedema attack: what happens to vasoactive mediators?

Ferrara, A. L., Bova, M., Petraroli, A., Veszeli, N., Galdiero, M. R., Braile, M., Marone, G., Cristinziano, L., Marcella, S., Modestino, L., Farkas, H. & Loffredo, S., Jan 2020, In : International Immunopharmacology. 78, 106079.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Hereditary angioedema C1-esterase inhibitor replacement therapy and coexisting autoimmune disorders: Findings from a claims database

Farkas, H., Levy, D., Supina, D., Berger, M., Prusty, S. & Fridman, M., May 27 2020, In : Allergy, Asthma and Clinical Immunology. 16, 1, 42.

Research output: Contribution to journalArticle

Open Access

Long-term efficacy and safety of subcutaneous C1-inhibitor in women with hereditary angioedema: Subgroup analysis from an open-label extension of a phase 3 trial

Levy, D. S., Farkas, H., Riedl, M. A., Hsu, F. I., Brooks, J. P., Cicardi, M., Feuersenger, H., Pragst, I. & Reshef, A., Feb 4 2020, In : Allergy, Asthma and Clinical Immunology. 16, 1, 8.

Research output: Contribution to journalArticle

Open Access

Long-term safety and efficacy of subcutaneous C1-inhibitor in older patients with hereditary angioedema

Bernstein, J. A., Schwartz, L., Yang, W., Baker, J., Anderson, J., Farkas, H., Aygören-Pürsün, E., Bygum, A., Jacobs, I., Feuersenger, H., Pragst, I. & Riedl, M. A., 2020, (Accepted/In press) In : Annals of Allergy, Asthma and Immunology.

Research output: Contribution to journalArticle

Open Access

Patterns of C1-Inhibitor/Plasma Serine Protease Complexes in Healthy Humans and in Hereditary Angioedema Patients

Kajdácsi, E., Jandrasics, Z., Veszeli, N., Makó, V., Koncz, A., Gulyás, D., Köhalmi, K. V., Temesszentandrási, G., Cervenák, L., Gál, P., Dobó, J., de Maat, S., Maas, C., Farkas, H. & Varga, L., May 5 2020, In : Frontiers in immunology. 11, 794.

Research output: Contribution to journalArticle

Open Access
2019

Delayed diagnosis of hereditary angioedema with C1-inhibitor deficiency in iranian children and adolescents

Ayazi, M., Fazlollahi, M. R., Mohammadzadeh, I., Fayezi, A., Nabavi, M., Mahdaviani, S. A., Movahedi, M., Heidarzadeh, M., Saghafi, S., Shokouhi Shoormasti, R., Mohammadian, S., Farkas, H. & Pourpak, Z., May 2019, In : Pediatric Allergy and Immunology. 30, 3, p. 395-398 4 p.

Research output: Contribution to journalLetter

Flow-mediated vasodilation assay indicates no endothelial dysfunction in hereditary angioedema patients with C1-inhibitor deficiency

Nebenführer, Z., Szabó, E., Kajdácsi, E., Kőhalmi, K. V., Karádi, I., Zsáry, A., Farkas, H. & Cervenák, L., Jan 1 2019, In : Annals of Allergy, Asthma and Immunology. 122, 1, p. 86-92 7 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Hereditary angioedema: examining the landscape of therapies and preclinical therapeutic targets

Farkas, H., Jun 3 2019, In : Expert Opinion on Therapeutic Targets. 23, 6, p. 457-459 3 p.

Research output: Contribution to journalEditorial

Open Access
6 Citations (Scopus)

Recombinant human C1 esterase inhibitor treatment for hereditary angioedema attacks in children

Reshef, A., Grivcheva-Panovska, V., Kessel, A., Kivity, S., Klimaszewska-Rembiasz, M., Moldovan, D., Farkas, H., Gutova, V., Fritz, S., Relan, A., Giannetti, B. & Magerl, M., Aug 2019, In : Pediatric Allergy and Immunology. 30, 5, p. 562-568 7 p.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)

Serum fetuin-A, tumor necrosis factor alpha and C-reactive protein concentrations in patients with hereditary angioedema with C1-inhibitor deficiency

Márkus, B., Veszeli, N., Temesszentandrási, G., Farkas, H. & Kalabay, L., Mar 18 2019, In : Orphanet journal of rare diseases. 14, 1, 67.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)
2018

Antibody-mediated inhibition of FXIIa blocks downstream bradykinin generation

Cao, H., Biondo, M., Lioe, H., Busfield, S., Rayzman, V., Nieswandt, B., Bork, K., Harrison, L. C., Auyeung, P., Farkas, H., Csuka, D., Pelzing, M., Dower, S., Wilson, M. J., Nash, A., Nolte, M. W. & Panousis, C., Oct 2018, In : Journal of Allergy and Clinical Immunology. 142, 4, p. 1355-1358 4 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Complete kinetic follow-up of symptoms and complement parameters during a hereditary angioedema attack

Veszeli, N., Kőhalmi, K. V., Kajdácsi, E., Gulyás, D., Temesszentandrási, G., Cervenak, L., Farkas, H. & Varga, L., Feb 1 2018, In : Allergy: European Journal of Allergy and Clinical Immunology. 73, 2, p. 516-520 5 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Diagnostyka wrodzonego obrzȩku naczynioruchowego

Translated title of the contribution: Diagnosis of hereditary angioedemaKoőhalmi, K. V., Cervenák, L. & Farkas, H., Dec 1 2018, In : Alergia Astma Immunologia. 23, 4, p. 168-174 7 p.

Research output: Contribution to journalArticle

Health-Related Quality of Life with Subcutaneous C1-Inhibitor for Prevention of Attacks of Hereditary Angioedema

Lumry, W. R., Craig, T., Zuraw, B., Longhurst, H., Baker, J., Li, H. H., Bernstein, J. A., Anderson, J., Riedl, M. A., Manning, M. E., Keith, P. K., Levy, D. S., Caballero, T., Banerji, A., Gower, R. G., Farkas, H., Lawo, J. P., Pragst, I., Machnig, T. & Watson, D. J., Sep 1 2018, In : Journal of Allergy and Clinical Immunology: In Practice. 6, 5, p. 1733-1741.e3

Research output: Contribution to journalArticle

16 Citations (Scopus)
6 Citations (Scopus)

Idiopathic Nonhistaminergic Acquired Angioedema Versus Hereditary Angioedema

Andrási, N., Veszeli, N., Kőhalmi, K. V., Csuka, D., Temesszentandrási, G., Varga, L. & Farkas, H., Jul 1 2018, In : Journal of Allergy and Clinical Immunology: In Practice. 6, 4, p. 1205-1208 4 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Investigational drugs in phase I and phase II clinical trials for hereditary angioedema

Farkas, H., Debreczeni, M. L. & Kőhalmi, K. V., Jan 2 2018, In : Expert Opinion on Investigational Drugs. 27, 1, p. 87-103 17 p.

Research output: Contribution to journalReview article

4 Citations (Scopus)

Lanadelumab for the Prophylactic Treatment of Hereditary Angioedema with C1 Inhibitor Deficiency: A Review of Preclinical and Phase I Studies

Busse, P. J., Farkas, H., Banerji, A., Lumry, W. R., Longhurst, H. J., Sexton, D. J. & Riedl, M. A., Jan 1 2018, (Accepted/In press) In : BioDrugs.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Pharmacological Management of Hereditary Angioedema with C1-Inhibitor Deficiency in Pediatric Patients

Farkas, H., Apr 1 2018, In : Pediatric Drugs. 20, 2, p. 135-151 17 p.

Research output: Contribution to journalReview article

6 Citations (Scopus)

Secreted phospholipases A2 in hereditary angioedema with C1-inhibitor deficiency

Loffredo, S., Ferrara, A. L., Bova, M., Borriello, F., Suffritti, C., Veszeli, N., Petraroli, A., Galdiero, M. R., Varricchi, G., Granata, F., Zanichelli, A., Farkas, H., Cicardi, M., Lambeau, G. & Marone, G., Jul 23 2018, In : Frontiers in immunology. 9, JUL, 1721.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Targeted next-generation sequencing for the molecular diagnosis of hereditary angioedema due to C1-inhibitor deficiency

Loules, G., Zamanakou, M., Parsopoulou, F., Vatsiou, S., Psarros, F., Csuka, D., Porebski, G., Obtulowicz, K., Valerieva, A., Staevska, M., López-Lera, A., López-Trascasa, M., Moldovan, D., Magerl, M., Maurer, M., Speletas, M., Farkas, H. & Germenis, A. E., Aug 15 2018, In : Gene. 667, p. 76-82 7 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Wybrane aspekty genotypowania wrodzonego obrzȩku naczynioruchowego w erze NGS: Gen F12

Translated title of the contribution: Aspects of hereditary angioedema genotyping in the era of NGS: The case of F12 geneVatsiou, S., Zamanakou, M., Loules, G., González-Quevedo, T., Porȩbski, G., Juchacz, A., Bova, M., Suffritti, C., Firinu, D., Csuka, D., Manousakis, E., Valerieva, A., Staevska, M., Magerl, M., Farkas, H. & Germenis, A. E., Dec 2018, In : Alergia Astma Immunologia. 23, 4, p. 205-210 6 p.

Research output: Contribution to journalArticle

2017

A novel prophylaxis with C1-inhibitor concentrate in hereditary angioedema during erythema marginatum

Kőhalmi, K. V., Veszeli, N., Cervenak, L., Varga, L. & Farkas, H., Sep 2017, In : Immunology letters. 189, p. 90-93 4 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Cleaved kininogen as a biomarker for bradykinin release in hereditary angioedema

Hofman, Z. L. M., de Maat, S., van Doorn, C., Sebastian, S. A. E., Pasterkamp, G., Maas, C., Hofman, Z. L. M., Hack, C. E., Suffritti, C., Zanichelli, A., Cicardi, M., Veszeli, N., Csuka, D., Farkas, H., Renné, T. & Renné, T., Dec 1 2017, In : Journal of Allergy and Clinical Immunology. 140, 6, p. 1700-1703.e8

Research output: Contribution to journalArticle

17 Citations (Scopus)

Genetic determinants of C1 inhibitor deficiency angioedema age of onset

Gianni, P., Loules, G., Zamanakou, M., Kompoti, M., Csuka, D., Psarros, F., Magerl, M., Moldovan, D., Maurer, M., Speletas, M. G., Farkas, H. & Germenis, A. E., Jan 1 2017, In : International archives of allergy and immunology. 174, 3-4, p. 200-204 5 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Glucocorticoid receptor gene polymorphisms in hereditary angioedema with C1-inhibitor deficiency

Zotter, Z., Nagy, Z., Patócs, A., Csuka, D., Veszeli, N., Kohalmi, K. V. & Farkas, H., Jan 10 2017, In : Orphanet journal of rare diseases. 12, 1, 5.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Health-related quality of life among children with hereditary angioedema

Engel-Yeger, B., Farkas, H., Kivity, S., Veszeli, N., Kőhalmi, K. V. & Kessel, A., Jun 1 2017, In : Pediatric Allergy and Immunology. 28, 4, p. 370-376 7 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)
65 Citations (Scopus)

Reply

Joseph, K., Constantino-Silva, R. N., Grumach, A. S., Feldweg, A., Wright, L., Frank, N., Vuzman, D., Sharma, R., Suffritti, C., Cicardi, M., Varga, L., Farkas, H., Bork, K. & Kaplan, A. P., May 2017, In : Journal of Allergy and Clinical Immunology. 139, 5, p. 1720-1721 2 p.

Research output: Contribution to journalLetter

2 Citations (Scopus)

The relationship between anxiety and quality of life in children with hereditary angioedema

Kessel, A., Farkas, H., Kivity, S., Veszeli, N., Kőhalmi, K. V. & Engel-Yeger, B., Nov 1 2017, In : Pediatric Allergy and Immunology. 28, 7, p. 692-698 7 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

The role of the complement system in hereditary angioedema

Csuka, D., Veszeli, N., Varga, L., Prohászka, Z. & Farkas, H., Sep 2017, In : Molecular Immunology. 89, p. 59-68 10 p.

Research output: Contribution to journalReview article

19 Citations (Scopus)

Treatment Effect and Safety of Icatibant in Pediatric Patients with Hereditary Angioedema

Farkas, H., Reshef, A., Aberer, W., Caballero, T., McCarthy, L., Hao, J., Nothaft, W., Schranz, J., Bernstein, J. A. & Li, H. H., Nov 2017, In : Journal of Allergy and Clinical Immunology: In Practice. 5, 6, p. 1671-1678.e2

Research output: Contribution to journalArticle

20 Citations (Scopus)
2016

Assessment of inhibitory antibodies in patients with hereditary angioedema treated with plasma-derived C1 inhibitor

Farkas, H., Varga, L., Moldovan, D., Obtulowicz, K., Shirov, T., Machnig, T., Feuersenger, H., Edelman, J., Williams-Herman, D. & Rojavin, M., Nov 1 2016, In : Annals of Allergy, Asthma and Immunology. 117, 5, p. 508-513 6 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Atrial natriuretic peptide as a novel biomarker of hereditary angioedema

Kajdácsi, E., Varga, L., Prohászka, Z., Farkas, H. & Cervenák, L., Apr 1 2016, In : Clinical Immunology. 165, p. 45-46 2 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Bacteriuria increases the risk of edematous attacks in hereditary angioedema with C1-inhibitor deficiency

Zotter, Z., Veszeli, N., Kőhalmi, K. V., Varga, L., Imreh, Kovács, G., Nallbani, M. & Farkas, H., Dec 1 2016, In : Allergy: European Journal of Allergy and Clinical Immunology. 71, 12, p. 1791-1793 3 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Conestat alfa: An orphan drug for the treatment of hereditary angioedema

Farkas, H., Apr 2 2016, In : Expert Opinion on Orphan Drugs. 4, 4, p. 443-452 10 p.

Research output: Contribution to journalArticle

Erythema marginatum as an early symptom of hereditary angioedema: Case report of 2 newborns

Martinez-Saguer, I. & Farkas, H., Feb 2016, In : Pediatrics. 137, 2, e20152411.

Research output: Contribution to journalArticle

15 Citations (Scopus)

First report of icatibant treatment in a pregnant patient with hereditary angioedema

Farkas, H., Kőhalmi, K. V., Veszeli, N., Tóth, F. & Varga, L., Aug 1 2016, In : Journal of Obstetrics and Gynaecology Research. 42, 8, p. 1026-1028 3 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Icatibant as acute treatment for hereditary angioedema in adults

Farkas, H., May 14 2016, (Accepted/In press) In : Expert Review of Clinical Pharmacology. p. 1-10 10 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Novel Vasoregulatory Aspects of Hereditary Angioedema: the Role of Arginine Vasopressin, Adrenomedullin and Endothelin-1

Kajdácsi, E., Jani, P. K., Csuka, D., Varga, L., Prohászka, Z., Farkas, H. & Cervenak, L., Feb 1 2016, In : Journal of Clinical Immunology. 36, 2, p. 160-170 11 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Psychometric Field Study of Hereditary Angioedema Quality of Life Questionnaire for Adults: HAE-QoL

Prior, N., Remor, E., Pérez-Fernández, E., Caminoa, M., Gómez-Traseira, C., Gayá, F., Aabom, A., Aberer, W., Betschel, S., Boccon-Gibod, I., Bouillet, L., Bygum, A., Csuka, D., Farkas, H., Gomide, M., Grumach, A., Leibovich, I., Malbran, A., Moldovan, D., Mihaly, E. & 9 others, Obtulowicz, K., Perpén, C., Peveling-Oberhag, A., Porebski, G., Chavannes, C. R., Reshef, A., Staubach, P., Wiednig, M. & Caballero, T., May 1 2016, In : Journal of Allergy and Clinical Immunology: In Practice. 4, 3, p. 464-473.e4

Research output: Contribution to journalArticle

19 Citations (Scopus)

Risk of thromboembolism in patients with hereditary angioedema treated with plasma-derived C1-inhibitor

Farkas, H., Kohalmi, K. V., Veszeli, N., Zotter, Z., Várnai, K. & Varga, L., Mar 1 2016, In : Allergy and Asthma Proceedings. 37, 2, p. 164-170 7 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

The effect of long-term danazol treatment on haematological parameters in hereditary angioedema Rare immune deficiencies

Kohalmi, K. V., Veszeli, N., Zotter, Z., Csuka, D., Benedek, S., Imreh, É., Varga, L. & Farkas, H., Feb 25 2016, In : Orphanet journal of rare diseases. 11, 1, 18.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Thromboembolierisiko bei hereditärem Angioödem unter Therapie mit plasmatischem C1-Esterase-Inhibitor

Farkas, H., Köhalmi, K. V., Veszeli, N., Zotter, Z., Värnai, K. & Varga, L., Mar 1 2016, In : Vasomed. 28, 2, p. 72-73 2 p.

Research output: Contribution to journalArticle