• 5176 Citations
  • 25 h-Index
19942019

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Article
2019

Covalently modified carboxyl side chains on cell surface leads to a novel method toward topology analysis of transmembrane proteins

Müller, A., Langó, T., Turiák, L., Ács, A., Várady, G., Kucsma, N., Drahos, L. & Tusnády, G. E., Dec 1 2019, In : Scientific reports. 9, 1, 15729.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Sequential, Structural and Functional Properties of Protein Complexes Are Defined by How Folding and Binding Intertwine

Mészáros, B., Dobson, L., Fichó, E., Tusnády, G. E., Dosztányi, Z. & Simon, I., Nov 8 2019, In : Journal of molecular biology. 431, 22, p. 4408-4428 21 p.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)

The TMCrys server for supporting crystallization of transmembrane proteins

Varga, J. K., Tusnády, G. E. & Valencia, A., Oct 15 2019, In : Bioinformatics. 35, 20, p. 4203-4204 2 p.

Research output: Contribution to journalArticle

Open Access
2018

NGS of virus-derived small RNAs as a diagnostic method used to determine viromes of Hungarian Vineyards

Czotter, N., Molnar, J., Szabó, E., Demian, E., Kontra, L., Baksa, I., Szittya, G., Kocsis, L., Deak, T., Bisztray, G., Tusnady, G. E., Burgyan, J. & Varallyay, E., Feb 6 2018, In : Frontiers in Microbiology. 9, FEB, 122.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Small RNA NGS revealed the presence of cherry virus A and little cherry virus 1 on apricots in hungary

Baráth, D., Jaksa-Czotter, N., Molnár, J., Varga, T., Balássy, J., Szabó, L. K., Kirilla, Z., Tusnády, G. E., Preininger, É. & Várallyay, É., Jun 11 2018, In : Viruses. 10, 6, 318.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Structural Principles Governing Disease-Causing Germline Mutations

Dobson, L., Mészáros, B. & Tusnády, G., Jan 1 2018, (Accepted/In press) In : Journal of Molecular Biology.

Research output: Contribution to journalArticle

3 Citations (Scopus)

TMCrys: Predict propensity of success for transmembrane protein crystallization

Varga, J. K. & Tusnády, G., Jan 1 2018, In : Bioinformatics. 34, 18, p. 3126-3130 5 p.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)
2017
5 Citations (Scopus)

TSTMP: Target selection for structural genomics of human transmembrane proteins

Varga, J., Dobson, L., Reményi, I. & Tusnády, G., Jan 1 2017, In : Nucleic Acids Research. 45, D1, p. D325-D330

Research output: Contribution to journalArticle

3 Citations (Scopus)
2016

A comprehensive survey of the mutagenic impact of common cancer cytotoxics

Szikriszt, B., PótiÁdám, Pipek, O., Krzystanek, M., Kanu, N., Molnár, J., Ribli, D., Szeltner, Z., Tusnády, G. E., Csabai, I., Szallasi, Z., Swanton, C. & Szüts, D., May 9 2016, In : Genome biology. 17, 1, p. 1-16 16 p., 99.

Research output: Contribution to journalArticle

76 Citations (Scopus)

Characterization of disease-associated mutations in human transmembrane proteins

Molnár, J., Szakács, G. & Tusnády, G. E., Mar 2016, In : PloS one. 11, 3, e0151760.

Research output: Contribution to journalArticle

17 Citations (Scopus)
2015

CCTOP: A Consensus Constrained TOPology prediction web server

Dobson, L., Reményi, I. & Tusnády, G. E., Jan 1 2015, In : Nucleic acids research. 43, W1, p. W408-W412

Research output: Contribution to journalArticle

117 Citations (Scopus)

Disordered regions in transmembrane proteins

Tusnády, G. E., Dobson, L. & Tompa, P., Nov 15 2015, In : Biochimica et Biophysica Acta - Biomembranes. 1848, 11, p. 2839-2848 10 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Expediting topology data gathering for the TOPDB database

Dobson, L., Langó, T., Reményi, I. & Tusnády, G. E., Jan 28 2015, In : Nucleic acids research. 43, D1, p. D283-D289

Research output: Contribution to journalArticle

23 Citations (Scopus)

Role of the N-terminal transmembrane domain in the endo-lysosomal targeting and function of the human ABCB6 protein

Kiss, K., Kucsma, N., Brozik, A., Tusnady, G. E., Bergam, P., Van Niel, G. & Szakacs, G., Apr 1 2015, In : Biochemical Journal. 467, 1, p. 127-139 13 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

The human transmembrane proteome

Dobson, L., Reményi, I. & Tusnády, G. E., May 28 2015, In : Biology Direct. 10, 1, 31.

Research output: Contribution to journalArticle

37 Citations (Scopus)

TMFoldRec: A statistical potential-based transmembrane protein fold recognition tool

Kozma, D. & Tusnády, G., Jun 30 2015, In : BMC Bioinformatics. 16, 1, 201.

Research output: Contribution to journalArticle

7 Citations (Scopus)

TMFoldWeb: A web server for predicting transmembrane protein fold class

Kozma, D. & Tusnády, G. E., Sep 17 2015, In : Biology Direct. 10, 1, 54.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2014

The genome of the chicken DT40 bursal lymphoma cell line

Molnár, J., Póti, Á., Pipek, O., Krzystanek, M., Kanu, N., Swanton, C., Tusnády, G. E., Szallasi, Z., Csabai, I. & Szüts, D., Jan 1 2014, In : G3: Genes, Genomes, Genetics. 4, 11, p. 2231-2240 10 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)
2013

PDBTM: Protein data bank of transmembrane proteins after 8 years

Kozma, D., Simon, I. & Tusnády, G. E., Jan 1 2013, In : Nucleic acids research. 41, D1, p. D524-D529

Research output: Contribution to journalArticle

134 Citations (Scopus)
2012

CMWeb: An interactive on-line tool for analysing residue-residue contacts and contact prediction methods

Kozma, D., Simon, I. & Tusnády, G. E., Jul 2012, In : Nucleic acids research. 40, W1, p. W329-W333

Research output: Contribution to journalArticle

15 Citations (Scopus)
2010

methGraph: A genome visualization tool for PCR-based methylation assays

Lefever, S., Hoebeeck, J., Pattyn, F., Tusnády, G., de Paepe, A., Speleman, F., Aarányi, T. & Vandesompele, J., Feb 2010, In : Epigenetics. 5, 2, p. 159-163 5 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Topology prediction of Helical Transmembrane proteins: How far have we reached?

Tusnády, G. E. & Simon, I., Dec 1 2010, In : Current Protein and Peptide Science. 11, 7, p. 550-561 12 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)
2009

New structural arrangement of the extracellular regions of the phosphate transporter SLC20A1, the receptor for gibbon ape leukemia virus

Farrell, K. B., Tusnady, G. E. & Eiden, M. V., Oct 23 2009, In : Journal of Biological Chemistry. 284, 43, p. 29979-29987 9 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)
2008

TOPDB: Topology data bank of transmembrane proteins

Tusnády, G. E., Kalmár, L. & Simon, I., Jan 2008, In : Nucleic acids research. 36, SUPPL. 1, p. D234-D239

Research output: Contribution to journalArticle

60 Citations (Scopus)

TOPDOM: Database of domains and motifs with conservative location in transmembrane proteins

Tusnády, G. E., Kalmár, L., Hegyi, H., Tompa, P. & Simon, I., Jun 2008, In : Bioinformatics. 24, 12, p. 1469-1470 2 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)
2006

The BiSearch web server

Arányi, T., Váradi, A., Simon, I. & Tusnády, G. E., Oct 5 2006, In : BMC bioinformatics. 7, 431.

Research output: Contribution to journalArticle

61 Citations (Scopus)
2005
Open Access
117 Citations (Scopus)

PDB_TM: Selection and membrane localization of transmembrane proteins in the protein data bank

Tusnády, G. E., Dosztányi, Z. & Simon, I., Jan 1 2005, In : Nucleic acids research. 33, DATABASE ISS., p. D275-D278

Research output: Contribution to journalArticle

219 Citations (Scopus)

SRide: A server for identifying stabilizing residues in proteins

Magyar, C., Gromiha, M. M., Pujadas, G., Tusnády, G. E. & Simon, I., Jul 2005, In : Nucleic acids research. 33, SUPPL. 2, p. W303-W305

Research output: Contribution to journalArticle

96 Citations (Scopus)

TMDET: Web server for detecting transmembrane regions of proteins by using their 3D coordinates

Tusnády, G. E., Dosztányi, Z. & Simon, I., Apr 1 2005, In : Bioinformatics. 21, 7, p. 1276-1277 2 p.

Research output: Contribution to journalArticle

103 Citations (Scopus)
2004

Transmembrane proteins in the Protein Data Bank: Identification and classification

Tusnády, G. E., Dosztányi, Z. & Simon, I., Nov 22 2004, In : Bioinformatics. 20, 17, p. 2964-2972 9 p.

Research output: Contribution to journalArticle

175 Citations (Scopus)
2003

PSORT-B: Improving protein subcellular localization prediction for Gram-negative bacteria

Gardy, J. L., Spencer, C., Wang, K., Ester, M., Tusnády, G. E., Simon, I., Hua, S., deFays, K., Lambert, C., Nakai, K. & Brinkman, F. S. L., Jul 1 2003, In : Nucleic acids research. 31, 13, p. 3613-3617 5 p.

Research output: Contribution to journalArticle

330 Citations (Scopus)

SCide: Identification of stabilization centers in proteins

Dosztányi, Z., Magyar, C., Tusnády, G. E. & Simon, I., May 1 2003, In : Bioinformatics. 19, 7, p. 899-900 2 p.

Research output: Contribution to journalArticle

94 Citations (Scopus)

Servers for sequence-structure relationship analysis and prediction

Dosztányi, Z., Magyar, C., Tusnády, G. E., Cserzo, M., Fiser, A. & Simon, I., Jul 1 2003, In : Nucleic acids research. 31, 13, p. 3359-3363 5 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
2002

The role of dimerization in prion replication

Tompa, P., Tusnády, G. E., Friedrich, P. & Simon, I., Jan 1 2002, In : Biophysical journal. 82, 4, p. 1711-1718 8 p.

Research output: Contribution to journalArticle

Open Access
43 Citations (Scopus)
2001

Prion protein: Evolution caught en route

Tompa, P., Tusnády, G. E., Cserzo, M. & Simon, I., Apr 10 2001, In : Proceedings of the National Academy of Sciences of the United States of America. 98, 8, p. 4431-4436 6 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

The HMMTOP transmembrane topology prediction server

Tusnády, G. E. & Simon, I., Jan 1 2001, In : Bioinformatics. 17, 9, p. 849-850 2 p.

Research output: Contribution to journalArticle

Open Access
1401 Citations (Scopus)

Topology of membrane proteins

Tusnády, G. E. & Simon, I., Mar 1 2001, In : Journal of Chemical Information and Computer Sciences. 41, 2, p. 364-368 5 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)
2000

Characterization of the amino-terminal regions in the human multidrug resistance protein (MRP1)

Bakos, E., Evers, R., Calenda, G., Tusnády, G. E., Szakács, G., Váradi, A. & Sarkadi, B., Dec 1 2000, In : Journal of cell science. 113, 24, p. 4451-4461 11 p.

Research output: Contribution to journalArticle

91 Citations (Scopus)
1999

Functional multidrug resistance protein (MRP1) lacking the N-terminal transmembrane domain

Bakos, É., Evers, R., Szakács, G., Tusnády, G. E., Welker, E., Szabó, K., De Haas, M., Van Deemter, L., Borst, P., Váradi, A. & Sarkadi, B., Nov 27 1999, In : Journal of Biological Chemistry. 273, 48, p. 32167-32175 9 p.

Research output: Contribution to journalArticle

245 Citations (Scopus)
1998
3 Citations (Scopus)
915 Citations (Scopus)
1997
212 Citations (Scopus)
1996

Membrane topology and glycosylation of the human multidrug resistance-associated proteins

Bakos, É., Hegedüs, T., Holló, Z., Welker, E., Tusnády, G. E., Zaman, G. J. R., Flens, M. J., Váradi, A. & Sarkadi, B., Jan 1 1996, In : Journal of Biological Chemistry. 271, 21, p. 12322-12326 5 p.

Research output: Contribution to journalArticle

Open Access
190 Citations (Scopus)
1995

Independence divergence-generated binary trees of amino acids

Tusnády, G. E., Tusnády, G. & Simon, I., May 1 1995, In : Protein Engineering, Design and Selection. 8, 5, p. 417-423 7 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
1994

Chaos game representation of protein structures

Fiser, A., Tusnády, G. E. & Simon, I., Dec 1994, In : Journal of Molecular Graphics. 12, 4, p. 302-304 3 p.

Research output: Contribution to journalArticle

63 Citations (Scopus)