• 3482 Citations
  • 32 h-Index
19952020

Research output per year

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Research Output

2020

Brain-dead donor heart conservation with a preservation solution supplemented by a conditioned medium from mesenchymal stem cells improves graft contractility after transplantation

Korkmaz-Icöz, S., Li, K., Loganathan, S., Ding, Q., Ruppert, M., Radovits, T., Brlecic, P., Sayour, A. A., Karck, M. & Szabó, G., Jan 1 2020, (Accepted/In press) In : American Journal of Transplantation.

Research output: Contribution to journalArticle

Open Access

Machine perfusion of circulatory determined death hearts: A scoping review

Saemann, L., Guo, Y., Ding, Q., Zhou, P., Karck, M., Szabó, G. & Wenzel, F., Jul 2020, In : Transplantation Reviews. 34, 3, 100551.

Research output: Contribution to journalReview article

Methane-Enriched Custodiol Preservation Solution Improves Graft Function in Experimental Model of Heterotopic Heart Transplantation

Benke, K., Ruppert, M., Sayour, A. A., Jász, D., Szilágyi, Tuboly, E., Baráth, B., Márton, A., Boros, M., Hartmann, P., Szabo, G., Hartyánszky, I., Szabolcs, Z., Merkely, B. & Radovits, T., Apr 1 2020, In : The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation. 39, 4, p. S351-S352

Research output: Contribution to journalArticle

Stimulation of soluble guanylate cyclase improves donor organ function in rat heart transplantation

Benke, K., Németh, B. T., Sayour, A. A., Stark, K. A., Oláh, A., Ruppert, M., Szabó, G., Korkmaz-Icöz, S., Horváth, E. M., Benkő, R., Hartyánszky, I., Szabolcs, Z., Merkely, B. & Radovits, T., Dec 1 2020, In : Scientific reports. 10, 1, 5358.

Research output: Contribution to journalArticle

Open Access
2019

Acute canagliflozin treatment protects against in vivo myocardial ischemia-reperfusion injury in non-diabetic male rats and enhances endothelium-dependent vasorelaxation

Sayour, A. A., Korkmaz-Icöz, S., Loganathan, S., Ruppert, M., Sayour, V. N., Oláh, A., Benke, K., Brune, M., Benko, R., Horváth, E. M., Karck, M., Merkely, B., Radovits, T. & Szabó, G., Apr 16 2019, In : Journal of Translational Medicine. 17, 1, 127.

Research output: Contribution to journalArticle

Open Access
12 Citations (Scopus)

Comparison of the reverse-remodeling effect of pharmacological soluble guanylate cyclase activation with pressure unloading in pathological myocardial left ventricular hypertrophy

Ruppert, M., Korkmaz-Icöz, S., Li, S., Brlecic, P., Németh, B. T., Oláh, A., Horváth, E. M., Veres, G., Pleger, S., Grabe, N., Merkely, B., Karck, M., Radovits, T. & Szabó, G., Jan 1 2019, In : Frontiers in Physiology. 10, JAN, 1869.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Hyperbilirubinaemia after cardiac surgery: the point of no return

Farag, M., Veres, G., Szabó, G., Ruhparwar, A., Karck, M. & Arif, R., Aug 1 2019, In : ESC Heart Failure. 6, 4, p. 694-700 7 p.

Research output: Contribution to journalArticle

Open Access

Hypothermic perfusion of donor heart with a preservation solution supplemented by mesenchymal stem cells

Korkmaz-Icöz, S., Li, S., Hüttner, R., Ruppert, M., Radovits, T., Loganathan, S., Sayour, A. A., Brlecic, P., Lasitschka, F., Karck, M. & Szabó, G., Jan 1 2019, (Accepted/In press) In : Journal of Heart and Lung Transplantation.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Incomplete structural reverse remodeling from late-stage left ventricular hypertrophy impedes the recovery of diastolic but not systolic dysfunction in rats

Ruppert, M., Korkmaz-Icöz, S., Loganathan, S., Jiang, W., Oláh, A., Sayour, A. A., Barta, B. A., Karime, C., Merkely, B., Karck, M., Radovits, T. & Szabó, G., Jun 2019, In : Journal of hypertension. 37, 6, p. 1200-1212 13 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Myofilament Ca 2+ sensitivity correlates with left ventricular contractility during the progression of pressure overload-induced left ventricular myocardial hypertrophy in rats

Ruppert, M., Bódi, B., Korkmaz-Icöz, S., Loganathan, S., Jiang, W., Lehmann, L., Oláh, A., Barta, B. A., Sayour, A. A., Merkely, B., Karck, M., Papp, Z., Szabó, G. & Radovits, T., Apr 2019, In : Journal of Molecular and Cellular Cardiology. 129, p. 208-218 11 p.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)

N-octanoyl dopamine is superior to dopamine in protecting graft contractile function when administered to the heart transplant recipients from brain-dead donors

Loganathan, S., Guo, Y., Jiang, W., Radovits, T., Ruppert, M., Sayour, A. A., Brune, M., Brlecic, P., Gude, P., Georgevici, A. I., Yard, B., Karck, M., Korkmaz-Icöz, S. & Szabó, G., Dec 2019, In : Pharmacological Research. 150, 104503.

Research output: Contribution to journalArticle

Patients at low surgical risk as defined by the Society of Thoracic Surgeons Score undergoing isolated interventional or surgical aortic valve implantation: In-hospital data and 1-year results from the German Aortic Valve Registry (GARY)

Bekeredjian, R., Szabo, G., Balaban, Ü., Bleiziffer, S., Bauer, T., Ensminger, S., Frerker, C., Herrmann, E., Beyersdorf, F., Hamm, C., Beckmann, A., Möllmann, H., Karck, M., Katus, H. A. & Walther, T., May 1 2019, In : European heart journal. 40, 17, p. 1323-1330 8 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)

Perkutane Mitralklappenrekonstruktion bei schwerer Mitralinsuffizienz nach Mitralklappenannuloplastie: MitraClip-in-the-ring als ergänzende Strategie

Translated title of the contribution: Percutaneous mitral valve repair in recurrent severe mitral valve regurgitation after mitral annuloplasty: MitraClip-in-the-ring as a complementary strategyPleger, S. T., Geis, N., Kreusser, M., Abu-Sharar, H., Sebening, C., Szabo, G., Katus, H. A. & Raake, P. W. J., Jan 1 2019, (Accepted/In press) In : Herz.

Research output: Contribution to journalArticle

The reimplantation valve-sparing aortic root replacement technique for patients with Marfan syndrome: A single-center experience

Kremer, J., Farag, M., Zaradzki, M., Szabó, G., Ruhparwar, A., Kallenbach, K., Karck, M. & Arif, R., Dec 1 2019, In : Scientific reports. 9, 1, 12021.

Research output: Contribution to journalArticle

Open Access

Twenty-year results of surgical pulmonary thromboembolectomy in acute pulmonary embolism

Mkalaluh, S., Szczechowicz, M., Karck, M. & Szabó, G., Jan 1 2019, In : Scandinavian Cardiovascular Journal.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2018

Early and long-term results of minimally invasive mitral valve surgery through a right mini-thoracotomy approach: A retrospective propensity-score matched analysis

Mkalaluh, S., Szczechowicz, M., Dib, B., Sabashnikov, A., Szabo, G., Karck, M. & Weymann, A., Jan 1 2018, In : PeerJ. 2018, 5, e4810.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Impact of Donor Core Body Temperature on Graft Survival after Heart Transplantation

Schnuelle, P., Benck, U., Krämer, B. K., Yard, B. A., Zuckermann, A., Wagner, F., Szabó, G., Borggrefe, M., Karck, M. & Gummert, J., Nov 1 2018, In : Transplantation. 102, 11, p. 1891-1900 10 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Impairment of the Akt pathway in transplanted Type 1 diabetic hearts is associated with post-transplant graft injury

Korkmaz-Icöz, S., Li, S., Loganathan, S., Radovits, T., Ruppert, M., Brlecic, P., Sayour, A. A., Veres, G., Fleming, T., Brune, M., Most, P., Karck, M. & Szabó, G., Dec 1 2018, In : Interactive Cardiovascular and Thoracic Surgery. 27, 6, p. 884-894 11 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Is internal thoracic artery resistant to reperfusion injury? Evaluation of the storage of free internal thoracic artery grafts

Veres, G., Schmidt, H., Hegedűs, P., Korkmaz-Icöz, S., Radovits, T., Loganathan, S., Brlecic, P., Li, S., Karck, M. & Szabó, G., Jan 1 2018, (Accepted/In press) In : Journal of Thoracic and Cardiovascular Surgery.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Mechanical pressure unloading therapy reverses thoracic aortic structural and functional changes in a hypertensive rat model

Korkmaz-Icöz, S., Brlecic, P., Ruppert, M., Radovits, T., Karck, M. & Szabó, G., Jan 1 2018, In : Journal of hypertension. 36, 12, p. 2350-2361 12 p.

Research output: Contribution to journalArticle

Olaparib protects cardiomyocytes against oxidative stress and improves graft contractility during the early phase after heart transplantation in rats

Korkmaz-Icöz, S., Szczesny, B., Marcatti, M., Li, S., Ruppert, M., Lasitschka, F., Loganathan, S., Szabó, C. & Szabó, G., Jan 1 2018, In : British Journal of Pharmacology. 175, 2, p. 246-261 16 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Open surgical thoracoabdominal aortic aneurysm repair: The Heidelberg experience

Mkalaluh, S., Szczechowicz, M., Dib, B., Weymann, A., Szabó, G. & Karck, M., Jan 1 2018, (Accepted/In press) In : Journal of Thoracic and Cardiovascular Surgery.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Pressure-volume analysis reveals characteristic sex-related differences in Cardiac function in a rat model of aortic banding-induced myocardial Hypertrophy

Ruppert, M., Korkmaz-Icöz, S., Loganathan, S., Jiang, W., Lehmann, L., Oláh, A., Sayour, A. A., Barta, B. A., Merkely, B., Karck, M., Radovits, T. & Szabó, G., Sep 1 2018, In : American Journal of Physiology - Heart and Circulatory Physiology. 315, 3, p. H502-H511

Research output: Contribution to journalArticle

6 Citations (Scopus)

Targeting phosphodiesterase 5 as a therapeutic option against myocardial ischaemia/reperfusion injury and for treating heart failure

Korkmaz-Icöz, S., Radovits, T. & Szabó, G., Jan 1 2018, In : British Journal of Pharmacology. 175, 2, p. 223-231 9 p.

Research output: Contribution to journalReview article

15 Citations (Scopus)

Targeting Phosphodiesterase-5 by Vardenafil Improves Vascular Graft Function

Veres, G., Hagenhoff, M., Schmidt, H., Radovits, T., Loganathan, S., Bai, Y., Korkmaz-Icöz, S., Brlecic, P., Sayour, A. A., Karck, M. & Szabó, G., Jan 1 2018, (Accepted/In press) In : European Journal of Vascular and Endovascular Surgery.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2017

Cinaciguat ameliorates glomerular damage by reducing ERK1/2 activity and TGF-ß expression in type-1 diabetic rats

Czirok, S., Fang, L., Radovits, T., Szabó, G., Szénási, G., Rosivall, L., Merkely, B. & Kökény, G., Dec 1 2017, In : Scientific reports. 7, 1, 11218.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Comparison of Two Miniaturized Cardiopulmonary Bypass Systems Regarding Inflammatory Response

Farag, M., Patil, N. P., Sabashnikov, A., Arif, R., Szabó, G., Kallenbach, K., Ruhparwar, A., Karck, M., Brenner, T., Hofer, S. & Weymann, A., Feb 1 2017, In : Artificial Organs. 41, 2, p. 139-145 7 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Impedimetric analysis of the effect of decellularized porcine heart scaffold on human fibrosarcoma, endothelial, and cardiomyocyte cell lines

Bäcker, H., Polgár, L., Soós, P., Lajkó, E., Láng, O., Merkely, B., Szabó, G., Dohmen, P. M., Weymann, A. & Kőhidai, L., May 11 2017, In : Medical Science Monitor. 23, p. 2232-2240 9 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Inverse remodelling of K2P 3.1 K+ channel expression and action potential duration in left ventricular dysfunction and atrial fibrillation: Implications for patient-specific antiarrhythmic drug therapy

Schmidt, C., Wiedmann, F., Zhou, X. B., Heijman, J., Voigt, N., Ratte, A., Lang, S., Kallenberger, S. M., Campana, C., Weymann, A., De Simone, R., Szabo, G., Ruhparwar, A., Kallenbach, K., Karck, M., Ehrlich, J. R., Baczkó, I., Borggrefe, M., Ravens, U., Dobrev, D. & 2 others, Katus, H. A. & Thomas, D., Jun 7 2017, In : European heart journal. 38, 22, p. 1764-1774 11 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Pharmacological preconditioning with gemfibrozil preserves cardiac function after heart transplantation

Benke, K., Mátyás, C., Sayour, A. A., Oláh, A., Németh, B. T., Ruppert, M., Szabó, G., Kökény, G., Horváth, E. M., Hartyánszky, I., Szabolcs, Z., Merkely, B. & Radovits, T., Dec 1 2017, In : Scientific reports. 7, 1, 14232.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Prevention of the development of heart failure with preserved ejection fraction by the phosphodiesterase-5A inhibitor vardenafil in rats with type 2 diabetes

Mátyás, C., Németh, B. T., Oláh, A., Török, M., Ruppert, M., Kellermayer, D., Barta, B. A., Szabó, G., Kökény, G., Horváth, E. M., Bódi, B., Papp, Z., Merkely, B. & Radovits, T., Mar 1 2017, In : European journal of heart failure. 19, 3, p. 326-336 11 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

Prolonging hypothermic ischaemic cardiac and vascular storage by inhibiting the activation of the nuclear enzyme poly(adenosine diphosphate-ribose) polymerase

Korkmaz-Icöz, S., Radovits, T., Loganathan, S., Li, S., Ruppert, M., Benke, K., Brlecic, P., Szabó, C., Karck, M. & Szabó, G., May 1 2017, In : European Journal of Cardio-thoracic Surgery. 51, 5, p. 829-835 7 p., ezw426.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Removal of a giant left ventricular thrombus after myocardial infarction due to dissection of left anterior descending artery

Seppelt, P. C., Brcic, A., Karck, M. & Szabó, G., Jun 1 2017, In : Interactive Cardiovascular and Thoracic Surgery. 24, 6, p. 964-966 3 p.

Research output: Contribution to journalArticle

Repair or replacement for isolated tricuspid valve pathology? Insights from a surgical analysis on long-term survival

Farag, M., Arif, R., Sabashnikov, A., Zeriouh, M., Popov, A. F., Ruhparwar, A., Schmack, B., Dohmen, P. M., Szabó, G., Karck, M. & Weymann, A., Feb 25 2017, In : Medical Science Monitor. 23, p. 1017-1025 9 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Reverse electrical remodeling following pressure unloading in a rat model of hypertension-induced left ventricular myocardial hypertrophy

Ruppert, M., Korkmaz-Icöz, S., Li, S., Merkely, B., Karck, M., Radovits, T. & Szabó, G., Jul 1 2017, In : Hypertension Research. 40, 7, p. 637-645 9 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Surgery for infective endocarditis: Outcomes and predictors of mortality in 360 consecutive patients

Farag, M., Borst, T., Sabashnikov, A., Zeriouh, M., Schmack, B., Arif, R., Beller, C. J., Popov, A. F., Kallenbach, K., Ruhparwar, A., Dohmen, P. M., Szabó, G., Karck, M. & Weymann, A., Jul 25 2017, In : Medical Science Monitor. 23, p. 3617-3626 10 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)
2016

Administration of zinc complex of acetylsalicylic acid after the onset of myocardial injury protects the heart by upregulation of antioxidant enzymes

Korkmaz-Icöz, S., Atmanli, A., Radovits, T., Li, S., Hegedüs, P., Ruppert, M., Brlecic, P., Yoshikawa, Y., Yasui, H., Karck, M. & Szabó, G., Mar 1 2016, In : Journal of Physiological Sciences. 66, 2, p. 113-125 13 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Cinaciguat prevents the development of pathologic hypertrophy in a rat model of left ventricular pressure overload

Németh, B. T., Mátyás, C., Oláh, A., Lux, Á., Hidi, L., Ruppert, M., Kellermayer, D., Kökény, G., Szabó, G., Merkely, B. & Radovits, T., Nov 17 2016, In : Scientific reports. 6, 37166.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Dimethyloxalylglycine treatment of brain-dead donor rats improves both donor and graft left ventricular function after heart transplantation

Hegedus, P., Li, S., Korkmaz-Icöz, S., Radovits, T., Mayer, T., Al Said, S., Brlecic, P., Karck, M., Merkely, B. & Szabó, G., Jan 1 2016, In : Journal of Heart and Lung Transplantation. 35, 1, p. 99-107 9 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Female Gender and Differences in Outcome after Isolated Coronary Artery Bypass Graft Surgery: Does Age Play a Role?

Arif, R., Farag, M., Gertner, V., Szabó, G., Weymann, A., Veres, G., Ruhparwar, A., Bekeredjian, R., Bruckner, T., Karck, M., Kallenbach, K. & Beller, C. J., Feb 1 2016, In : PLoS One. 11, 2, e0145371.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Influence of antithymocyte globulin treatment of brain-dead organ donor on inflammatory response in cardiac grafts: an experimental study in mice

Kremer, J., Muschitz, G. K., Aumayr, K., Moser, P., Szabó, G., Weymann, A., Zuckermann, A. & Podesser, B. K., Dec 1 2016, In : Transplant International. 29, 12, p. 1329-1336 8 p.

Research output: Contribution to journalArticle

Left ventricular pressure-volume measurements and myocardial gene expression profile in type 2 diabetic Goto-Kakizaki rats

Korkmaz-Icöz, S., Lehner, A., Li, S., Vater, A., Radovits, T., Brune, M., Ruppert, M., Sun, X., Brlecic, P., Zorn, M., Karck, M. & Szabó, G., 2016, In : American Journal of Physiology - Heart and Circulatory Physiology. 311, 4, p. H958-H971

Research output: Contribution to journalArticle

9 Citations (Scopus)

Myocardial reverse remodeling after pressure unloading is associated with maintained cardiac mechanoenergetics in a rat model of left ventricular hypertrophy

Ruppert, M., Korkmaz-Icöz, S., Li, S., Németh, B. T., Hegedűs, P., Brlecic, P., Mátyás, C., Zorn, M., Merkely, B., Karck, M., Radovits, T. & Szabó, G., Sep 1 2016, In : American Journal of Physiology - Heart and Circulatory Physiology. 311, 3, p. H592-H603

Research output: Contribution to journalArticle

15 Citations (Scopus)

Oral treatment with a zinc complex of acetylsalicylic acid prevents diabetic cardiomyopathy in a rat model of type-2 diabetes: Activation of the Akt pathway

Korkmaz-Icöz, S., Al Said, S., Radovits, T., Li, S., Brune, M., Hegedus, P., Atmanli, A., Ruppert, M., Brlecic, P., Lehmann, L. H., Lahrmann, B., Grabe, N., Yoshikawa, Y., Yasui, H., Most, P., Karck, M. & Szabó, G., May 6 2016, In : Cardiovascular diabetology. 15, 1, p. 1-16 16 p., 75.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Response to letter regarding article, "upregulation of K2P3.1 K+ current causes action potential shortening in patients with chronic atrial fibrillation"

Schmidt, C., Wiedmann, F., Voigt, N., Zhou, X. B., Heijman, J., Lang, S., Albert, V., Kallenberger, S., Ruhparwar, A., Szabó, G., Kallenbach, K., Karck, M., Borggrefe, M., Biliczki, P., Ehrlich, J. R., Baczkó, I., Lugenbiel, P., Schweizer, P. A., Donner, B. C., Katus, H. A. & 2 others, Dobrev, D. & Thomas, D., Jan 1 2016, In : Circulation. 133, 11, p. e440-e441

Research output: Contribution to journalLetter

2 Citations (Scopus)

Rolle der löslichen Guanylatzyklase im Modell der Herztransplantation in der Ratte

Translated title of the contribution: Effects of soluble guanylate cyclase activation on heart transplantation in a rat modelLoganathan, S., Korkmaz-Icöz, S., Radovits, T., Li, S., Mikles, B., Barnucz, E., Hirschberg, K., Karck, M. & Szabó, G., Jul 5 2016, (Accepted/In press) In : Zeitschrift fur Herz-, Thorax- und Gefasschirurgie. p. 1-7 7 p.

Research output: Contribution to journalArticle

2015

An altered pattern of myocardial histopathological and molecular changes underlies the different characteristics of type-1 and type-2 diabetic cardiac dysfunction

Radovits, T., Korkmaz, S., Mátyás, C., Oláh, A., Németh, B. T., Páli, S., Hirschberg, K., Zubarevich, A., Gwanmesia, P. N., Li, S., Loganathan, S., Barnucz, E., Merkely, B. & Szabó, G., Jan 5 2015, In : Journal of Diabetes Research. 2015, 728741.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Atrioventricular node ablation in langendorff-perfused porcine hearts using carbon ion particle therapy

Lehmann, H. I., Richter, D., Prokesch, H., Graeff, C., Prall, M., Simoniello, P., Fournier, C., Bauer, J., Kaderka, R., Weymann, A., Szabo, G., Sonnenberg, K., Constantinescu, A. M., Johnson, S. B., Misiri, J., Takami, M., Miller, R. C., Herman, M. G., Asirvatham, S. J., Brons, S. & 6 others, Jäkel, O., Haberer, T., Debus, J., Durante, M., Bert, C. & Packer, D. L., Apr 20 2015, In : Circulation: Arrhythmia and Electrophysiology. 8, 2, p. 429-438 10 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Cardiac effects of acute exhaustive exercise in a rat model

Oláh, A., Németh, B. T., Mátyás, C., Horváth, E. M., Hidi, L., Birtalan, E., Kellermayer, D., Ruppert, M., Merkely, G., Szabó, G., Merkely, B. & Radovits, T., Jan 1 2015, In : International Journal of Cardiology. 182, C, p. 258-266 9 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)