• 14834 Citations
  • 70 h-Index
1987 …2019
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Research Output 1987 2019

2015
13 Citations (Scopus)

Alcohol and HCV: Implications for liver cancer

Szabó, G., Saha, B. & Bukong, T. N., 2015, In : Advances in Experimental Medicine and Biology. 815, p. 197-216 20 p.

Research output: Contribution to journalArticle

Liver Neoplasms
Liver
Alcohols
Medical problems
Viruses
2 Citations (Scopus)

Alcoholic and non-alcoholic fatty liver disease: Bench to bedside

Chalasani, N. & Szabó, G., Jan 1 2015, Springer International Publishing. 372 p.

Research output: Book/ReportBook

Alcoholic Fatty Liver
Liver
Epidemiology
Animal Models
Therapeutics
20 Citations (Scopus)

Alcoholic hepatitis and HCV interactions in the modulation of liver disease

Punzalan, C. S., Bukong, T. N. & Szabo, G., Oct 1 2015, In : Journal of Viral Hepatitis. 22, 10, p. 769-776 8 p.

Research output: Contribution to journalReview article

Alcoholic Hepatitis
Hepacivirus
Liver Diseases
Virus Diseases
Alcohols
33 Citations (Scopus)

Alcohol-induced miR-27a regulates differentiation and M2 macrophage polarization of normal human monocytes

Saha, B., Bruneau, J. C., Kodys, K. & Szabó, G., Apr 1 2015, In : Journal of Immunology. 194, 7, p. 3079-3087 9 p.

Research output: Contribution to journalArticle

MicroRNAs
Monocytes
Macrophages
Alcohols
Hepacivirus
64 Citations (Scopus)

Alcohol’s effect on host defense

Szabó, G. & Saha, B., Jun 27 2015, In : Alcohol Research: Current Reviews. 37, 2

Research output: Contribution to journalReview article

Alcohols
Adaptive Immunity
Virus Diseases
Bacterial Infections
Immune System
55 Citations (Scopus)

Biodistribution and function of extracellular miRNA-155 in mice

Bala, S., Csak, T., Momen-Heravi, F., Lippai, D., Kodys, K., Catalano, D., Satishchandran, A., Ambros, V. & Szabó, G., May 29 2015, In : Scientific Reports. 5, 10721.

Research output: Contribution to journalArticle

MicroRNAs
Exosomes
Adipose Tissue
Liver
Kupffer Cells
105 Citations (Scopus)

Exosomes derived from alcohol-treated hepatocytes horizontally transfer liver specific miRNA-122 and sensitize monocytes to LPS

Momen-Heravi, F., Bala, S., Kodys, K. & Szabó, G., May 14 2015, In : Scientific Reports. 5, 9991.

Research output: Contribution to journalArticle

Exosomes
MicroRNAs
Monocytes
Hepatocytes
Alcohols
11 Citations (Scopus)

Gaps in Knowledge and Research Priorities for Alcoholic Hepatitis

Sanyal, A. J., Gao, B. & Szabó, G., Jul 1 2015, In : Gastroenterology. 149, 1, p. 4-9 6 p., 59786.

Research output: Contribution to journalArticle

198 Citations (Scopus)

Gut-liver axis in alcoholic liver disease

Szabó, G., Jan 1 2015, In : Gastroenterology. 148, 1, p. 30-36 7 p.

Research output: Contribution to journalReview article

Alcoholic Liver Diseases
Liver
Endotoxins
Alcohol Drinking
Toll-Like Receptor 4
107 Citations (Scopus)

Increased number of circulating exosomes and their microRNA cargos are potential novel biomarkers in alcoholic hepatitis

Momen-Heravi, F., Saha, B., Kodys, K., Catalano, D., Satishchandran, A. & Szabó, G., Aug 12 2015, In : Journal of Translational Medicine. 13, 1, 261.

Research output: Contribution to journalArticle

Exosomes
Alcoholic Hepatitis
Biomarkers
MicroRNAs
Alcohols
173 Citations (Scopus)

Inflammasome activation and function in liver disease

Szabó, G. & Petrasek, J., Jul 3 2015, In : Nature Reviews Gastroenterology and Hepatology. 12, 7, p. 387-400 14 p.

Research output: Contribution to journalReview article

Inflammasomes
Liver Diseases
Inflammation
Caspase 1
Interleukin-1
11 Citations (Scopus)

Inflammasome activation in the liver: Focus on alcoholic and non-alcoholic steatohepatitis

Szabó, G. & Iracheta-Vellve, A., Sep 1 2015, In : Clinics and Research in Hepatology and Gastroenterology. 39, p. S18-S23

Research output: Contribution to journalShort survey

Inflammasomes
Fatty Liver
Liver
Alcoholic Hepatitis
Interleukin-1
39 Citations (Scopus)

Inhibition of sterile danger signals, uric acid and ATP, prevents inflammasome activation and protects from alcoholic steatohepatitis in mice

Iracheta-Vellve, A., Petrasek, J., Satishchandran, A., Gyongyosi, B., Saha, B., Kodys, K., Fitzgerald, K. A., Kurt-Jones, E. A. & Szabó, G., Nov 1 2015, In : Journal of Hepatology. 63, 5, p. 1147-1155 9 p.

Research output: Contribution to journalArticle

Alcoholic Fatty Liver
Inflammasomes
Uric Acid
Adenosine Triphosphate
Interleukin-1
21 Citations (Scopus)

Krüppel-like factor 4 is a transcriptional regulator of M1/M2 macrophage polarization in alcoholic liver disease

Saha, B., Bala, S., Hosseini, N., Kodys, K. & Szabó, G., May 1 2015, In : Journal of Leukocyte Biology. 97, 5, p. 963-973 11 p.

Research output: Contribution to journalArticle

Alcoholic Liver Diseases
Macrophages
Alcohols
Acetaldehyde
Liver
46 Citations (Scopus)

Metabolic danger signals, uric acid and ATP, mediate inflammatory cross-talk between hepatocytes and immune cells in alcoholic liver disease

Petrasek, J., Iracheta-Vellve, A., Saha, B., Satishchandran, A., Kodys, K., Fitzgerald, K. A., Kurt-Jones, E. A. & Szabó, G., Aug 1 2015, In : Journal of Leukocyte Biology. 98, 2, p. 249-256 8 p.

Research output: Contribution to journalArticle

Alcoholic Liver Diseases
Uric Acid
Hepatocytes
Adenosine Triphosphate
Inflammation
60 Citations (Scopus)

microRNA-122 regulates hypoxia-inducible factor-1 and vimentin in hepatocytes and correlates with fibrosis in diet-induced steatohepatitis

Csak, T., Bala, S., Lippai, D., Satishchandran, A., Catalano, D., Kodys, K. & Szabó, G., Feb 1 2015, In : Liver International. 35, 2, p. 532-541 10 p.

Research output: Contribution to journalArticle

Hypoxia-Inducible Factor 1
Vimentin
Fatty Liver
Choline
MicroRNAs
39 Citations (Scopus)

MicroRNA-155 deficiency attenuates liver steatosis and fibrosis without reducing inflammation in a mouse model of steatohepatitis

Csak, T., Bala, S., Lippai, D., Kodys, K., Catalano, D., Iracheta-Vellve, A. & Szabó, G., Jun 4 2015, In : PLoS One. 10, 6, e0129251.

Research output: Contribution to journalArticle

liver cirrhosis
fatty liver
Fatty Liver
Choline
MicroRNAs
27 Citations (Scopus)

MicroRNAs in alcoholic liver disease

Szabó, G. & Satishchandran, A., Feb 1 2015, In : Seminars in Liver Disease. 35, 1, p. 36-42 7 p.

Research output: Contribution to journalArticle

Alcoholic Liver Diseases
MicroRNAs
Alcohols
Liver Circulation
Alcoholic Hepatitis

Preface

Chalasani, N. & Szabó, G., Jan 1 2015, Alcoholic and Non-Alcoholic Fatty Liver Disease: Bench to Bedside. Springer International Publishing, p. vii-viii

Research output: Chapter in Book/Report/Conference proceedingForeword/postscript

47 Citations (Scopus)
Fatty Liver
Nutrition
Sugars
Liver
Tumors
4 Citations (Scopus)

The genetics of hepatitis C virus underlie its ability to escape humoral immunity

Kolls, J. K. & Szabó, G., Jan 2 2015, In : Journal of Clinical Investigation. 125, 1, p. 97-98 2 p.

Research output: Contribution to journalReview article

Humoral Immunity
Hepacivirus
Vaccines
Antibody Binding Sites
Viral Envelope Proteins
1 Citation (Scopus)

Treatment of alcoholic liver disease including emerging therapies, novel targets, and liver transplantation

Petrasek, J. & Szabó, G., Jan 1 2015, Alcoholic and Non-Alcoholic Fatty Liver Disease: Bench to Bedside. Springer International Publishing, p. 291-311 21 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Alcoholic Liver Diseases
Alcoholic Hepatitis
Liver Transplantation
Pentoxifylline
Adrenal Cortex Hormones
2014
138 Citations (Scopus)

Acute binge drinking increases serum endotoxin and bacterial DNA levels in healthy individuals

Bala, S., Marcos, M., Gattu, A., Catalano, D. & Szabó, G., May 14 2014, In : PLoS One. 9, 5, e96864.

Research output: Contribution to journalArticle

Binge Drinking
Bacterial DNA
binging
endotoxins
blood serum

Alcoholic liver disease

Szabo, G., Jan 1 2014, Liver Immunology: Principles and Practice. Springer International Publishing, p. 331-343 13 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Alcoholic Liver Diseases
Alcohols
Adaptive Immunity
Cytoplasmic and Nuclear Receptors
Innate Immunity
3 Citations (Scopus)

A novel human radixin peptide inhibits hepatitis C virus infection at the level of cell entry

Bukong, T. N., Kodys, K. & Szabó, G., 2014, In : International Journal of Peptide Research and Therapeutics. 20, 3, p. 269-276 8 p.

Research output: Contribution to journalArticle

Virus Diseases
Viruses
Hepacivirus
Peptides
Hinges
29 Citations (Scopus)

Both bone marrow-derived and non-bone marrow-derived cells contribute to AIM2 and NLRP3 inflammasome activation in a MyD88- dependent manner in dietary steatohepatitis

Csak, T., Pillai, A., Ganz, M., Lippai, D., Petrasek, J., Park, J. K., Kodys, K., Dolganiuc, A., Kurt-Jones, E. A. & Szabó, G., 2014, In : Liver International. 34, 9, p. 1402-1413 12 p.

Research output: Contribution to journalArticle

Inflammasomes
Fatty Liver
Melanoma
Bone Marrow
Interleukin-1
42 Citations (Scopus)

Converging actions of alcohol on liver and brain immune signaling

Szabó, G. & Lippai, D., 2014, In : International Review of Neurobiology. 118, p. 359-380 22 p.

Research output: Contribution to journalArticle

Alcohols
Liver
Brain
Alcohol Drinking
Encephalitis
98 Citations (Scopus)

Exosome-mediated delivery of functionally active miRNA-155 inhibitor to macrophages

Momen-Heravi, F., Bala, S., Bukong, T. & Szabó, G., Oct 1 2014, In : Nanomedicine: Nanotechnology, Biology, and Medicine. 10, 7, p. 1517-1527 11 p.

Research output: Contribution to journalArticle

Exosomes
Macrophages
MicroRNAs
Cells
Biomolecules
154 Citations (Scopus)

Exosomes from Hepatitis C Infected Patients Transmit HCV Infection and Contain Replication Competent Viral RNA in Complex with Ago2-miR122-HSP90

Bukong, T. N., Momen-Heravi, F., Kodys, K., Bala, S. & Szabó, G., Oct 1 2014, In : PLoS Pathogens. 10, 10

Research output: Contribution to journalArticle

Exosomes
Viral RNA
Hepatitis C
Infection
Proton Pumps
51 Citations (Scopus)

High fat diet feeding results in gender specific steatohepatitis and inflammasome activation

Ganz, M., Csak, T. & Szabó, G., Jul 14 2014, In : World Journal of Gastroenterology. 26, p. 8525-8534 10 p.

Research output: Contribution to journalArticle

Inflammasomes
High Fat Diet
Fatty Liver
Insulin Resistance
Triglycerides
24 Citations (Scopus)

Innate immune cell networking in hepatitis C virus infection

Saha, B. & Szabó, G., Nov 1 2014, In : Journal of Leukocyte Biology. 96, 5, p. 757-766 10 p.

Research output: Contribution to journalReview article

Virus Diseases
Hepacivirus
Immune System
Viruses
Antiviral Agents
42 Citations (Scopus)

Micro-RNA-155 Deficiency Prevents Alcohol-Induced Serum Endotoxin Increase and Small Bowel Inflammation in Mice

Lippai, D., Bala, S., Catalano, D., Kodys, K. & Szabó, G., 2014, In : Alcoholism: Clinical and Experimental Research. 38, 8, p. 2217-2224 8 p.

Research output: Contribution to journalArticle

MicroRNAs
Endotoxins
Alcohols
Inflammation
Serum
2013
34 Citations (Scopus)

Alcohol Facilitates HCV RNA Replication Via Up-Regulation of miR-122 Expression and Inhibition of Cyclin G1 in Human Hepatoma Cells

Hou, W., Bukong, T. N., Kodys, K. & Szabó, G., Apr 2013, In : Alcoholism: Clinical and Experimental Research. 37, 4, p. 599-608 10 p.

Research output: Contribution to journalArticle

Cyclin G1
Virus Replication
MicroRNAs
Viruses
Hepacivirus
95 Citations (Scopus)

Alcohol-induced IL-1β in the brain is mediated by NLRP3/ASC inflammasome activation that amplifies neuroinflammation

Lippai, D., Bala, S., Petrasek, J., Csak, T., Levin, I., Kurt-Jones, E. A. & Szabó, G., Jul 2013, In : Journal of Leukocyte Biology. 94, 1, p. 171-182 12 p.

Research output: Contribution to journalArticle

Inflammasomes
Interleukin-1
Alcohols
HMGB1 Protein
Brain
4 Citations (Scopus)

Another armed CD4+ T cell ready to battle hepatocellular carcinoma

Cabrera, R. & Szabó, G., Jul 2013, In : Hepatology. 58, 1, p. 1-3 3 p.

Research output: Contribution to journalArticle

CD4-Positive T-Lymphocytes
Forkhead Transcription Factors
Chronic Hepatitis B
Cytotoxic T-Lymphocytes
Liver Neoplasms
53 Citations (Scopus)

Binge Ethanol and Liver: New Molecular Developments

Shukla, S. D., Pruett, S. B., Szabó, G. & Arteel, G. E., Apr 2013, In : Alcoholism: Clinical and Experimental Research. 37, 4, p. 550-557 8 p.

Research output: Contribution to journalArticle

Liver
Alcoholic Liver Diseases
Ethanol
Epigenomics
Alcohol Drinking
24 Citations (Scopus)

CD81/CD9 tetraspanins aid plasmacytoid dendritic cells in recognition of hepatitis C virus-infected cells and induction of interferon-alpha

Zhang, S., Kodys, K., Babcock, G. J. & Szabó, G., Sep 2013, In : Hepatology. 58, 3, p. 940-949 10 p.

Research output: Contribution to journalArticle

Tetraspanins
Interferon-alpha
Hepacivirus
Dendritic Cells
Interferons
68 Citations (Scopus)

Chronic Alcohol-Induced microRNA-155 Contributes to Neuroinflammation in a TLR4-Dependent Manner in Mice

Lippai, D., Bala, S., Csak, T., Kurt-Jones, E. A. & Szabó, G., Aug 9 2013, In : PLoS One. 8, 8, e70945.

Research output: Contribution to journalArticle

Toll-Like Receptor 4
MicroRNAs
microRNA
alcohols
Alcohols
16 Citations (Scopus)

Differences in innate immune signaling between alcoholic and non-alcoholic steatohepatitis

Petrasek, J., Csak, T., Ganz, M. & Szabó, G., 2013, In : Journal of Gastroenterology and Hepatology (Australia). 28, SUPPL 1, p. 93-98 6 p.

Research output: Contribution to journalReview article

Alcoholic Fatty Liver
Fatty Liver
Inflammasomes
Toll-Like Receptor 4
Innate Immunity
29 Citations (Scopus)

Ethanol facilitates hepatitis C virus replication via up-regulation of GW182 and heat shock protein 90 in human hepatoma cells

Bukong, T. N., Hou, W., Kodys, K. & Szabó, G., Jan 2013, In : Hepatology. 57, 1, p. 70-80 11 p.

Research output: Contribution to journalArticle

HSP90 Heat-Shock Proteins
Virus Replication
Hepacivirus
Hepatocellular Carcinoma
Ethanol

Hepatic immunology

Szabó, G. & Bruneau, J., Jul 29 2013, Viral Hepatitis: Fourth Edition. wiley, p. 13-25 13 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Allergy and Immunology
Liver
Digestion
Hepatocytes
Immune System
18 Citations (Scopus)

Human ezrin-moesin-radixin proteins modulate hepatitis C virus infection

Bukong, T. N., Kodys, K. & Szabó, G., Nov 2013, In : Hepatology. 58, 5, p. 1569-1579 11 p.

Research output: Contribution to journalArticle

Virus Diseases
Hepacivirus
Proteins
moesin
radixin
58 Citations (Scopus)

Human monoclonal antibody MBL-HCV1 delays HCV viral rebound following liver transplantation: A randomized controlled study

Chung, R. T., Gordon, F. D., Curry, M. P., Schiano, T. D., Emre, S., Corey, K., Markmann, J. F., Hertl, M., Pomposelli, J. J., Pomfret, E. A., Florman, S., Schilsky, M., Broering, T. J., Finberg, R. W., Szabó, G., Zamore, P. D., Khettry, U., Babcock, G. J., Ambrosino, D. M., Leav, B. & 3 others, Leney, M., Smith, H. L. & Molrine, D. C., Apr 2013, In : American Journal of Transplantation. 13, 4, p. 1047-1054 8 p.

Research output: Contribution to journalArticle

Hepacivirus
Liver Transplantation
Monoclonal Antibodies
Placebos
Viral Load
81 Citations (Scopus)

Human type 2 myeloid dendritic cells produce interferon-λ and amplify interferon-α in response to hepatitis C virus infection

Zhang, S., Kodys, K., Li, K. & Szabó, G., Feb 2013, In : Gastroenterology. 144, 2

Research output: Contribution to journalArticle

Virus Diseases
Myeloid Cells
Hepacivirus
Dendritic Cells
Interferons
32 Citations (Scopus)

IFN-γ production by human natural killer cells in response to HCV-infected hepatoma cells is dependent on accessory cells

Zhang, S., Saha, B., Kodys, K. & Szabó, G., Sep 2013, In : Journal of Hepatology. 59, 3, p. 442-449 8 p.

Research output: Contribution to journalArticle

Natural Killer Cells
Hepacivirus
Interferons
Hepatocellular Carcinoma
Blood Cells
75 Citations (Scopus)

Immune and inflammatory pathways in NASH

Ganz, M. & Szabó, G., Dec 1 2013, In : Hepatology International. 7, p. S771-S781

Research output: Contribution to journalReview article

Immune System
Pattern Recognition Receptors
Inflammation
Non-alcoholic Fatty Liver Disease
304 Citations (Scopus)

MicroRNAs in liver disease

Szabó, G. & Bala, S., Sep 2013, In : Nature Reviews Gastroenterology and Hepatology. 10, 9, p. 542-552 11 p.

Research output: Contribution to journalReview article

MicroRNAs
Liver Diseases
Liver
Liver Cirrhosis
Inflammation
3 Citations (Scopus)

Reply

Szabó, G. & Bala, S., Jun 2013, In : Hepatology. 57, 6, p. 2547 1 p.

Research output: Contribution to journalLetter

Exosomes
Chemical and Drug Induced Liver Injury
Alcoholic Liver Diseases
MicroRNAs
Hepatitis
121 Citations (Scopus)

STING-IRF3 pathway links endoplasmic reticulum stress with hepatocyte apoptosis in early alcoholic liver disease

Petrasek, J., Iracheta-Vellve, A., Csak, T., Satishchandran, A., Kodys, K., Kurt-Jones, E. A., Fitzgerald, K. A. & Szabó, G., Oct 8 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 41, p. 16544-16549 6 p.

Research output: Contribution to journalArticle

Interferon Regulatory Factor-3
Alcoholic Liver Diseases
Endoplasmic Reticulum Stress
Interferons
Hepatocytes
44 Citations (Scopus)

Toll-Like Receptors in Liver Disease

Petrasek, J., Csak, T. & Szabó, G., 2013, In : Advances in Clinical Chemistry. 59, p. 155-201 47 p.

Research output: Contribution to journalArticle

Alcoholic Liver Diseases
Toll-Like Receptors
Liver
Liver Diseases
Endotoxins