• 14834 Citations
  • 70 h-Index
1987 …2019
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Research Output 1987 2019

Article
46 Citations (Scopus)

Aberrations in post-trauma monocyte (Mø) subpopulation: Role in septic shock syndrome

Miller-Graziano, C. L., Szabó, G., Kodys, K. & Griffey, K., 1990, In : Journal of Trauma - Injury, Infection and Critical Care. 30, 12, p. S86-S97

Research output: Contribution to journalArticle

Septic Shock
Monocytes
Immunoglobulin G
Monokines
Interleukin-6
7 Citations (Scopus)

Abnormal neutrophil traps and impaired efferocytosis contribute to liver injury and sepsis severity after binge alcohol use

Bukong, T. N., Cho, Y., Iracheta-Vellve, A., Saha, B., Lowe, P., Adejumo, A., Furi, I., Ambade, A., Gyongyosi, B., Catalano, D., Kodys, K. & Szabó, G., Jan 1 2018, (Accepted/In press) In : Journal of Hepatology.

Research output: Contribution to journalArticle

Sepsis
Neutrophils
Alcohols
Liver
Wounds and Injuries
14 Citations (Scopus)

Acceptance of an ABO-Incompatible Mismatched (AB+ to O+) Liver Allograft With the Use of Daclizumab and Mycophenolate Mofetil

Fang, W. C., Saltzman, J., Rososhansky, S., Szabó, G., Heard, S. O., Banner, B., Chari, R. & Katz, E., 2000, In : Liver Transplantation. 6, 4, p. 497-500 4 p.

Research output: Contribution to journalArticle

Mycophenolic Acid
Muromonab-CD3
Allografts
Alprostadil
Liver
49 Citations (Scopus)

Acute alcohol activates STAT3, AP-1, and Sp-1 transcription factors via the family of Src kinases to promote IL-10 production in human monocytes

Norkina, O., Dolganiuc, A., Shapiro, T., Kodys, K., Mandrekar, P. & Szabó, G., Sep 1 2007, In : Journal of Leukocyte Biology. 82, 3, p. 752-762 11 p.

Research output: Contribution to journalArticle

Sp1 Transcription Factor
src-Family Kinases
Transcription Factor AP-1
Interleukin-10
Monocytes
59 Citations (Scopus)

Acute alcohol consumption attenuates interleukin-8 (IL-8) and monocyte chemoattractant peptide-1 (MCP-1) induction in response to ex vivo stimulation

Szabó, G., Chavan, S., Mandrekar, P. & Catalano, D., 1999, In : Journal of Clinical Immunology. 19, 1, p. 67-76 10 p.

Research output: Contribution to journalArticle

Chemotactic Factors
Interleukin-8
Alcohol Drinking
Monocytes
Peptides
53 Citations (Scopus)

Acute alcohol consumption inhibits accessory cell function of monocytes and dendritic cells

Szabó, G., Catalano, D., White, B. & Mandrekar, P., May 2004, In : Alcoholism: Clinical and Experimental Research. 28, 5, p. 824-828 5 p.

Research output: Contribution to journalArticle

Accessories
Alcohol Drinking
Dendritic Cells
Monocytes
Alcohols
37 Citations (Scopus)

Acute alcohol exposure exerts anti-inflammatory effects by inhibiting IκB kinase activity and p65 phosphorylation in human monocytes

Mandrekar, P., Jeliazkova, V., Catalano, D. & Szabó, G., Jun 15 2007, In : Journal of Immunology. 178, 12, p. 7686-7693 8 p.

Research output: Contribution to journalArticle

eIF-2 Kinase
Monocytes
Anti-Inflammatory Agents
Phosphorylation
Alcohols
48 Citations (Scopus)
Toll-Like Receptor 4
Tumor Necrosis Factor Receptors
Interleukin-1
Chemical activation
Alcohols
42 Citations (Scopus)

Acute alcohol intake induces SOCS1 and SOCS3 and inhibits cytokine-induced STAT1 and STAT3 signaling in human monocytes

Norkina, O., Dolganiuc, A., Catalano, D., Kodys, K., Mandrekar, P., Syed, A., Efros, M. & Szabó, G., Sep 2008, In : Alcoholism: Clinical and Experimental Research. 32, 9, p. 1565-1573 9 p.

Research output: Contribution to journalArticle

Monocytes
Interleukin-6
Alcohols
Cytokines
Suppressor of Cytokine Signaling Proteins
46 Citations (Scopus)

Acute and chronic alcohol abuse modulate immunity

Brown, L. A. S., Cook, R. T., Jerrells, T. R., Kolls, J. K., Nagy, L. E., Szabó, G., Wands, J. R. & Kovacs, E. J., Sep 2006, In : Alcoholism: Clinical and Experimental Research. 30, 9, p. 1624-1631 8 p.

Research output: Contribution to journalArticle

Alcoholism
Immunity
Alcohols
Public Opinion
Ethanol
138 Citations (Scopus)

Acute binge drinking increases serum endotoxin and bacterial DNA levels in healthy individuals

Bala, S., Marcos, M., Gattu, A., Catalano, D. & Szabó, G., May 14 2014, In : PLoS One. 9, 5, e96864.

Research output: Contribution to journalArticle

Binge Drinking
Bacterial DNA
binging
endotoxins
blood serum
35 Citations (Scopus)

Acute ethanol consumption synergizes with trauma to increase monocyte tumor necrosis factor α production late postinjury

Szabó, G., Mandrekar, P., Verma, B., Isaac, A. & Catalano, D., Nov 1994, In : Journal of Clinical Immunology. 14, 6, p. 340-352 13 p.

Research output: Contribution to journalArticle

Monocytes
Ethanol
Tumor Necrosis Factor-alpha
Wounds and Injuries
Acetylmuramyl-Alanyl-Isoglutamine
11 Citations (Scopus)

Acute ethanol treatment augments interleukin-12 production in activated human monocytes

Szabó, G., Girouard, L., Mandrekar, P. & Catalano, D., 1996, In : Annals of the New York Academy of Sciences. 795, p. 422-425 4 p.

Research output: Contribution to journalArticle

Interleukin-12
Monocytes
Ethanol
76 Citations (Scopus)

Acute ethanol treatment modulates Toll-like receptor-4 association with lipid rafts

Dolganiuc, A., Bakis, G., Kodys, K., Mandrekar, P. & Szabó, G., Jan 2006, In : Alcoholism: Clinical and Experimental Research. 30, 1, p. 76-85 10 p.

Research output: Contribution to journalArticle

Toll-Like Receptor 4
Ethanol
Alcohols
Association reactions
Lipids
14 Citations (Scopus)

Acute-on-Chronic Liver Failure: Getting Ready for Prime Time?

Bajaj, J. S., Moreau, R., Kamath, P. S., Vargas, H. E., Arroyo, V., Reddy, K. R., Szabó, G., Tandon, P., Olson, J., Karvellas, C., Gustot, T., Lai, J. C. & Wong, F., Jan 1 2018, (Accepted/In press) In : Hepatology.

Research output: Contribution to journalArticle

Northern Asia
Transplants
Precipitating Factors
Mortality
Liver
51 Citations (Scopus)

Additive inhibition of dendritic cell allostimulatory capacity by alcohol and hepatitis C is not restored by DC maturation and involves abnormal IL-10 and IL-2 induction

Dolganiuc, A., Kodys, K., Kopasz, A., Marshall, C., Mandrekar, P. & Szabó, G., Jun 1 2003, In : Alcoholism: Clinical and Experimental Research. 27, 6, p. 1023-1031 9 p.

Research output: Contribution to journalArticle

Hepatitis C
Interleukin-10
Dendritic Cells
Viruses
Interleukin-2
12 Citations (Scopus)

Adult mouse model of early hepatocellular carcinoma promoted by alcoholic liver disease

Ambade, A., Satishchandran, A., Gyongyosi, B., Lowe, P. & Szabó, G., Apr 28 2016, In : World Journal of Gastroenterology. 22, 16, p. 4091-4108 18 p.

Research output: Contribution to journalArticle

Alcoholic Liver Diseases
Nitrosamines
Hepatocellular Carcinoma
Alcohols
Liver

Advanced Molecular Biologic Techniques in Toxicologic Disease

Ward, J., Szabó, G., McManus, D. & Boyer, E., Dec 2011, In : Journal of Medical Toxicology. 7, 4, p. 288-294 7 p.

Research output: Contribution to journalArticle

Point-of-Care Systems
MicroRNAs
Nanoparticles
Patient Care
Research Personnel
29 Citations (Scopus)

A functional serotonin transporter gene polymorphism and depressive effects associated with interferon-α treatment

Pierucci-Lagha, A., Covault, J., Bonkovsky, H. L., Feinn, R., Abreu, C., Sterling, R. K., Fontana, R. J., Kranzler, H. R., Szabó, G., Cormier, M., Giansiracusa, D., Kelley, M., DiBisceglie, A. M., Bacon, B., Neuschwander-Tetri, B., King, D., Dienstag, J. L., Reid, A. E., Chung, R. T., Molchen, W. A. & 40 others, Everson, G. T., De-Santo, J., McKinley, C., Morgan, T. R., Hoefs, J. C., Park, C., Lee, W. M., Shelton, J., Crowder, N., Elbein, R., Lindsay, K. L., Jones, C. B., Milstein, S. L., Lok, A. S. F., Richtmyer, P. A., Shiffman, M. L., Hofmann, C., Smith, P., Ghany, M. G., Liang, T. J., Park, Y., Rivera, E., Haynes-Williams, V., Everhart, J. E., Seeff, L. B., Robuck, P. R., Hoofnagle, J. H., Wright, E. C., Morishima, C., Gretch, D. R., Chung, M., Padmanabhan, L., Curto, T. M., Massey, L. J., Goodman, Z. D., Davis, G. L., Garcia-Tsao, G., Kutner, M., Lemon, S. M. & Perrillo, R. P., Mar 2010, In : Psychosomatics. 51, 2, p. 137-148 12 p.

Research output: Contribution to journalArticle

Serotonin Plasma Membrane Transport Proteins
Interferons
Interferon-alpha
Depression
Genes
13 Citations (Scopus)

Alcohol and HCV: Implications for liver cancer

Szabó, G., Saha, B. & Bukong, T. N., 2015, In : Advances in Experimental Medicine and Biology. 815, p. 197-216 20 p.

Research output: Contribution to journalArticle

Liver Neoplasms
Liver
Alcohols
Medical problems
Viruses
12 Citations (Scopus)

Alcohol and susceptibility to tuberculosis

Szabó, G., 1997, In : Alcohol Research and Health. 21, 1, p. 39-41 3 p.

Research output: Contribution to journalArticle

Tuberculosis
Alcohols
35 Citations (Scopus)

Alcohol Exposure as a Risk Factor for Adverse Outcomes in Elective Surgery

Nath, B., Li, Y. F., Carroll, J. E., Szabo, G., Tseng, J. F. & Shah, S. A., 2010, In : Journal of Gastrointestinal Surgery. 14, 11, p. 1732-1741 10 p.

Research output: Contribution to journalArticle

Alcohols
Length of Stay
Alcohol Drinking
Surgical Wound Infection
Wounds and Injuries
34 Citations (Scopus)

Alcohol Facilitates HCV RNA Replication Via Up-Regulation of miR-122 Expression and Inhibition of Cyclin G1 in Human Hepatoma Cells

Hou, W., Bukong, T. N., Kodys, K. & Szabó, G., Apr 2013, In : Alcoholism: Clinical and Experimental Research. 37, 4, p. 599-608 10 p.

Research output: Contribution to journalArticle

Cyclin G1
Virus Replication
MicroRNAs
Viruses
Hepacivirus

Alcoholic Hepatitis: A Review

Hosseini, N., Shor, J. & Szabó, G., Jul 1 2019, In : Alcohol and alcoholism (Oxford, Oxfordshire). 54, 4, p. 408-416 9 p.

Research output: Contribution to journalArticle

Alcoholic Hepatitis
Liver
Fibrosis
Alcoholic Liver Diseases
Alcohols
31 Citations (Scopus)

Alcoholic hepatitis accelerates early hepatobiliary cancer by increasing stemness and MIR-122-mediated HIF-1α activation

Ambade, A., Satishchandran, A. & Szabó, G., Feb 18 2016, In : Scientific Reports. 6, 21340.

Research output: Contribution to journalArticle

Alcoholic Hepatitis
Nitrosamines
Alcohols
Alcoholic Fatty Liver
Liver
1 Citation (Scopus)

Alcohol-induced IL-17A production in Paneth cells amplifies endoplasmic reticulum stress, apoptosis, and inflammasome-IL-18 activation in the proximal small intestine in mice

Gyongyosi, B., Cho, Y., Lowe, P., Calenda, C. D., Iracheta-Vellve, A., Satishchandran, A., Ambade, A. & Szabó, G., Jan 1 2019, In : Mucosal Immunology.

Research output: Contribution to journalArticle

Paneth Cells
Inflammasomes
Interleukin-18
Endoplasmic Reticulum Stress
Interleukin-17
95 Citations (Scopus)

Alcohol-induced IL-1β in the brain is mediated by NLRP3/ASC inflammasome activation that amplifies neuroinflammation

Lippai, D., Bala, S., Petrasek, J., Csak, T., Levin, I., Kurt-Jones, E. A. & Szabó, G., Jul 2013, In : Journal of Leukocyte Biology. 94, 1, p. 171-182 12 p.

Research output: Contribution to journalArticle

Inflammasomes
Interleukin-1
Alcohols
HMGB1 Protein
Brain
13 Citations (Scopus)

Alcohol-induced miR-155 and HDAC11 inhibit negative regulators of the TLR4 pathway and lead to increased LPS responsiveness of Kupffer cells in alcoholic liver disease

Bala, S., Csak, T., Kodys, K., Catalano, D., Ambade, A., Furi, I., Lowe, P., Cho, Y., Iracheta-Vellve, A. & Szabó, G., Aug 1 2017, In : Journal of Leukocyte Biology. 102, 2, p. 487-498 12 p.

Research output: Contribution to journalArticle

Alcoholic Liver Diseases
Kupffer Cells
Alcohols
Interleukin-10
Cytokines
33 Citations (Scopus)

Alcohol-induced miR-27a regulates differentiation and M2 macrophage polarization of normal human monocytes

Saha, B., Bruneau, J. C., Kodys, K. & Szabó, G., Apr 1 2015, In : Journal of Immunology. 194, 7, p. 3079-3087 9 p.

Research output: Contribution to journalArticle

MicroRNAs
Monocytes
Macrophages
Alcohols
Hepacivirus
69 Citations (Scopus)

Alcohol-induced regulation of nuclear regulatory factor-κβ in human monocytes

Mandrekar, P., Catalano, D. & Szabó, G., 1997, In : Alcoholism: Clinical and Experimental Research. 21, 6, p. 988-994 7 p.

Research output: Contribution to journalArticle

Monocytes
Ethanol
Alcohols
Chemical activation
Cytokines
25 Citations (Scopus)

Alcohol-related changes in the intestinal icrobiome influence neutrophil infiltration, inflammation and steatosis in early alcoholic hepatitis in mice

Lowe, P. P., Gyongyosi, B., Satishchandran, A., Iracheta-Vellve, A., Ambade, A., Kodys, K., Catalano, D., Ward, D. V. & Szabó, G., Mar 1 2017, In : PLoS One. 12, 3, e0174544.

Research output: Contribution to journalArticle

alcoholic hepatitis
Alcoholic Hepatitis
Neutrophil Infiltration
Infiltration
neutrophils
1 Citation (Scopus)

Alcohol-Related Liver Disease: Areas of Consensus, Unmet Needs and Opportunities for Further Study

Szabó, G., Kamath, P. S., Shah, V. H., Thursz, M. & Mathurin, P., Jan 1 2019, (Accepted/In press) In : Hepatology.

Research output: Contribution to journalArticle

Liver Diseases
Consensus
Alcohols
Alcoholic Liver Diseases
Alcohol Drinking
83 Citations (Scopus)

Alcohol's contribution to compromised immunity

Szabó, G., 1997, In : Alcohol Research and Health. 21, 1, p. 30-38 9 p.

Research output: Contribution to journalArticle

Immunity
Alcohols
Alcoholics
Immune System
Somatotypes
140 Citations (Scopus)

An essential role for monocyte chemoattractant protein-1 in alcoholic liver injury: Regulation of proinflammatory cytokines and hepatic steatosis in mice

Mandrekar, P., Ambade, A., Lim, A., Szabó, G. & Catalano, D., Dec 2011, In : Hepatology. 54, 6, p. 2185-2197 13 p.

Research output: Contribution to journalArticle

Chemokine CCL2
Alcohols
Cytokines
Liver
Wounds and Injuries
4 Citations (Scopus)

Another armed CD4+ T cell ready to battle hepatocellular carcinoma

Cabrera, R. & Szabó, G., Jul 2013, In : Hepatology. 58, 1, p. 1-3 3 p.

Research output: Contribution to journalArticle

CD4-Positive T-Lymphocytes
Forkhead Transcription Factors
Chronic Hepatitis B
Cytotoxic T-Lymphocytes
Liver Neoplasms
3 Citations (Scopus)

A novel human radixin peptide inhibits hepatitis C virus infection at the level of cell entry

Bukong, T. N., Kodys, K. & Szabó, G., 2014, In : International Journal of Peptide Research and Therapeutics. 20, 3, p. 269-276 8 p.

Research output: Contribution to journalArticle

Virus Diseases
Viruses
Hepacivirus
Peptides
Hinges
18 Citations (Scopus)

Antigen presentation by the CD4 positive monocyte subset

Szabó, G., Miller, C. L. & Kodys, K., 1990, In : Journal of Leukocyte Biology. 47, 2, p. 111-120 10 p.

Research output: Contribution to journalArticle

Antigen Presentation
Antigen-Presenting Cells
Monocytes
Prostaglandins E
Interleukin-1
106 Citations (Scopus)

A prospective study of the rate of progression in compensated, histologically advanced chronic hepatitis C

Dienstag, J. L., Ghany, M. G., Morgan, T. R., Di Bisceglie, A. M., Bonkovsky, H. L., Kim, H. Y., Seeff, L. B., Szabó, G., Wright, E. C., Sterling, R. K., Everson, G. T., Lindsay, K. L., Lee, W. M., Lok, A. S., Morishima, C., Stoddard, A. M. & Everhart, J. E., Aug 2011, In : Hepatology. 54, 2, p. 396-405 10 p.

Research output: Contribution to journalArticle

Chronic Hepatitis C
Fibrosis
Prospective Studies
Disease Progression
Liver Diseases
1 Citation (Scopus)

A Toll-like receptorok jelentosége a sebészeti szepszis pathomechanizmusában.

Translated title of the contribution: Significance of Toll-like receptors in the pathophysiology of surgical sepsisRomics, L., Coffey, J. C., Wang, J. H., Redmond, H. P. & Szabó, G., 2004, In : Magyar sebészet. 57, 4, p. 229-235 7 p.

Research output: Contribution to journalArticle

Toll-Like Receptors
Sepsis
Adaptive Immunity
Inflammatory Bowel Diseases
Innate Immunity
53 Citations (Scopus)

Binge Ethanol and Liver: New Molecular Developments

Shukla, S. D., Pruett, S. B., Szabó, G. & Arteel, G. E., Apr 2013, In : Alcoholism: Clinical and Experimental Research. 37, 4, p. 550-557 8 p.

Research output: Contribution to journalArticle

Liver
Alcoholic Liver Diseases
Ethanol
Epigenomics
Alcohol Drinking
55 Citations (Scopus)

Biodistribution and function of extracellular miRNA-155 in mice

Bala, S., Csak, T., Momen-Heravi, F., Lippai, D., Kodys, K., Catalano, D., Satishchandran, A., Ambros, V. & Szabó, G., May 29 2015, In : Scientific Reports. 5, 10721.

Research output: Contribution to journalArticle

MicroRNAs
Exosomes
Adipose Tissue
Liver
Kupffer Cells
1 Citation (Scopus)

Biomarkers of Macrophage Activation and Immune Danger Signals Predict Clinical Outcomes in Alcoholic Hepatitis

Saha, B., Tornai, D., Kodys, K., Adejumo, A., Lowe, P., McClain, C., Mitchell, M., McCullough, A., Dasarathy, S., Kroll-Desrosiers, A., Barton, B., Radaeva, S. & Szabó, G., Oct 1 2019, In : Hepatology. 70, 4, p. 1134-1149 16 p.

Research output: Contribution to journalArticle

Alcoholic Hepatitis
Macrophage Activation
Biomarkers
Osteopontin
End Stage Liver Disease
18 Citations (Scopus)

Bone marrow-derived immune cells mediate sensitization to liver injury in a myeloid differentiation factor 88-dependent fashion

Hritz, I., Velayudham, A., Dolganiuc, A., Kodys, K., Mandrekar, P., Kurt-Jones, E. & Szabó, G., Oct 2008, In : Hepatology. 48, 4, p. 1342-1347 6 p.

Research output: Contribution to journalArticle

Myeloid Differentiation Factor 88
Bone Marrow
Liver
Propionibacterium acnes
Wounds and Injuries
29 Citations (Scopus)

Both bone marrow-derived and non-bone marrow-derived cells contribute to AIM2 and NLRP3 inflammasome activation in a MyD88- dependent manner in dietary steatohepatitis

Csak, T., Pillai, A., Ganz, M., Lippai, D., Petrasek, J., Park, J. K., Kodys, K., Dolganiuc, A., Kurt-Jones, E. A. & Szabó, G., 2014, In : Liver International. 34, 9, p. 1402-1413 12 p.

Research output: Contribution to journalArticle

Inflammasomes
Fatty Liver
Melanoma
Bone Marrow
Interleukin-1
24 Citations (Scopus)

CD81/CD9 tetraspanins aid plasmacytoid dendritic cells in recognition of hepatitis C virus-infected cells and induction of interferon-alpha

Zhang, S., Kodys, K., Babcock, G. J. & Szabó, G., Sep 2013, In : Hepatology. 58, 3, p. 940-949 10 p.

Research output: Contribution to journalArticle

Tetraspanins
Interferon-alpha
Hepacivirus
Dendritic Cells
Interferons
68 Citations (Scopus)

Chronic Alcohol-Induced microRNA-155 Contributes to Neuroinflammation in a TLR4-Dependent Manner in Mice

Lippai, D., Bala, S., Csak, T., Kurt-Jones, E. A. & Szabó, G., Aug 9 2013, In : PLoS One. 8, 8, e70945.

Research output: Contribution to journalArticle

Toll-Like Receptor 4
MicroRNAs
microRNA
alcohols
Alcohols
11 Citations (Scopus)

Circulating and exosome-packaged hepatitis c single-stranded RNA induce monocyte differentiation via tlr7/8 to polarized macrophages and fibrocytes

Saha, B., Kodys, K., Adejumo, A. & Szabó, G., Mar 1 2017, In : Journal of Immunology. 198, 5, p. 1974-1984 11 p.

Research output: Contribution to journalArticle

Exosomes
Hepacivirus
Hepatitis
Monocytes
Macrophages
347 Citations (Scopus)

Circulating microRNAs in exosomes indicate hepatocyte injury and inflammation in alcoholic, drug-induced, and inflammatory liver diseases

Bala, S., Petrasek, J., Mundkur, S., Catalano, D., Levin, I., Ward, J., Alao, H., Kodys, K. & Szabó, G., Nov 2012, In : Hepatology. 56, 5, p. 1946-1957 12 p.

Research output: Contribution to journalArticle

Exosomes
Chemical and Drug Induced Liver Injury
MicroRNAs
Hepatocytes
Acetaminophen
2 Citations (Scopus)

Clinical Trial Design for Alcoholic Hepatitis

Szabó, G., Nov 1 2017, In : Seminars in Liver Disease. 37, 4, p. 332-342 11 p.

Research output: Contribution to journalArticle

Alcoholic Hepatitis
Clinical Trials
Vulnerable Populations
Alcoholic Liver Diseases
Industry
42 Citations (Scopus)

Converging actions of alcohol on liver and brain immune signaling

Szabó, G. & Lippai, D., 2014, In : International Review of Neurobiology. 118, p. 359-380 22 p.

Research output: Contribution to journalArticle

Alcohols
Liver
Brain
Alcohol Drinking
Encephalitis