G. Szabó &ndash; Research Output

1987

Human macrophages degrade tryptophan upon induction by interferon-gamma

Werner, E. R., Bitterlich, G., Fuchs, D., Hausen, A., Reibnegger, G., Szabó, G., Dierich, M. P. & Wachter, H., Jul 20 1987, In : Life Sciences. 41, 3, p. 273-280 8 p.

Research output: Contribution to journal › Article

Macrophages

Tryptophan

Interferon-gamma

T-cells

Phytohemagglutinins

1988

122 Citations (Scopus)

Mechanisms of Altered Monocyte Prostaglandin E2 Production in Severely Injured Patients

Miller-Graziano, C. L., Fink, M., Yan, J., Szabó, G. & Kodys, K., 1988, In : Archives of Surgery. 123, 3, p. 293-299 7 p.

Research output: Contribution to journal › Article

Dinoprostone

Monocytes

Wounds and Injuries

Lymphocytes

Acetylmuramyl-Alanyl-Isoglutamine

46 Citations (Scopus)

Selective induction of mononuclear phagocytes to produce neopterin by interferons

Bitterlich, G., Szabó, G., Werner, E. R., Larcher, C., Fuchs, D., Hausen, A., Reibnegger, G., Schulz, T. F., Troppmair, J., Wachter, H. & Dierich, M. P., 1988, In : Immunobiology. 176, 3, p. 228-235 8 p.

Research output: Contribution to journal › Article

Neopterin

Phagocytes

Interferons

Interferon-gamma

Monocytes

1990

46 Citations (Scopus)

Aberrations in post-trauma monocyte (Mø) subpopulation: Role in septic shock syndrome

Miller-Graziano, C. L., Szabó, G., Kodys, K. & Griffey, K., 1990, In : Journal of Trauma - Injury, Infection and Critical Care. 30, 12, p. S86-S97

Research output: Contribution to journal › Article

Septic Shock

Monocytes

Immunoglobulin G

Monokines

Interleukin-6

18 Citations (Scopus)

Antigen presentation by the CD4 positive monocyte subset

Szabó, G., Miller, C. L. & Kodys, K., 1990, In : Journal of Leukocyte Biology. 47, 2, p. 111-120 10 p.

Research output: Contribution to journal › Article

Antigen Presentation

Antigen-Presenting Cells

Monocytes

Prostaglandins E

Interleukin-1

40 Citations (Scopus)

Differential tumor necrosis factor production by human monocyte subsets

Szabo, G., Miller-Graziano, C. L., Wu, J. Y., Takayama, T. & Kodys, K., 1990, In : Journal of Leukocyte Biology. 47, 3, p. 206-216 11 p.

Research output: Contribution to journal › Article

Monocytes

Tumor Necrosis Factor-alpha

Dinoprostone

Interferon-gamma

human TNF protein

61 Citations (Scopus)

Elevated Tumor Necrosis Factorα Production Concomitant to Elevated Prostaglandin E2 Production by Trauma Patients' Monocytes

Takayama, T. K., Miller, C. & Szabó, G., 1990, In : Archives of Surgery. 125, 1, p. 29-35 7 p.

Research output: Contribution to journal › Article

Dinoprostone

Monocytes

Tumor Necrosis Factor-alpha

Wounds and Injuries

Sepsis

12 Citations (Scopus)

Induction and regulation of monocyte procoagulant activity

Szabó, G. & Miller-Graziano, C. L., 1990, In : Transplantation. 50, 2, p. 301-309 9 p.

Research output: Contribution to journal › Article

Acetylmuramyl-Alanyl-Isoglutamine

Dinoprostone

Interleukin-4

Down-Regulation

Antigen-Antibody Complex

1991

31 Citations (Scopus)

Elevated monocyte interleukin-6 (IL-6) production in immunosuppressed trauma patients. I. Role of FcγRI cross-linking stimulation

Szabó, G., Kodys, K. & Miller-Graziano, C. L., Nov 1991, In : Journal of Clinical Immunology. 11, 6, p. 326-335 10 p.

Research output: Contribution to journal › Article

Monocytes

Interleukin-6

Wounds and Injuries

Interleukin-1

Hypergammaglobulinemia

21 Citations (Scopus)

Elevated monocyte interleukin-6 (IL-6) production in immunosuppressed trauma patients. II. Downregulation by IL-4

Szabó, G., Kodys, K. & Miller-Graziano, C. L., Nov 1991, In : Journal of Clinical Immunology. 11, 6, p. 336-344 9 p.

Research output: Contribution to journal › Article

Interleukin-4

Monocytes

Interleukin-6

Down-Regulation

Acetylmuramyl-Alanyl-Isoglutamine

101 Citations (Scopus)

Role of elevated monocyte transforming growth factorβ (TGFβ) production in posttrauma immunosuppression

Miller-Graziano, C. L., Szabó, G., Griffey, K., Mehta, B., Kodys, K. & Catalano, D., Mar 1991, In : Journal of Clinical Immunology. 11, 2, p. 95-102 8 p.

Research output: Contribution to journal › Article

Transforming Growth Factors

Immunosuppression

Monocytes

Dinoprostone

Wounds and Injuries

1992

43 Citations (Scopus)

Induction of transforming growth factor-beta and prostaglandin E2 production by ethanol in human monocytes

Szabó, G., Verma, B. K., Fogarasi, M. & Catalano e., D., 1992, In : Journal of Leukocyte Biology. 52, 6, p. 602-610 9 p.

Research output: Contribution to journal › Article

Dinoprostone

Transforming Growth Factor beta

Monocytes

Ethanol

Acetylmuramyl-Alanyl-Isoglutamine

1993

88 Citations (Scopus)

Down-regulation of tumor necrosis factor α activity by acute ethanol treatment in human peripheral blood monocytes

Verma, B. K., Fogarasi, M. & Szabó, G., Jan 1993, In : Journal of Clinical Immunology. 13, 1, p. 8-22 15 p.

Research output: Contribution to journal › Article

Monocytes

Ethanol

Down-Regulation

Tumor Necrosis Factor-alpha

Acetylmuramyl-Alanyl-Isoglutamine

73 Citations (Scopus)

Selective inhibition of antigen-specific T lymphocyte proliferation by acute ethanol exposure: The role of impaired monocyte antigen presentation capacity and mediator production

Szabó, G., Verma, B. & Catalano, D., 1993, In : Journal of Leukocyte Biology. 54, 6, p. 534-544 11 p.

Research output: Contribution to journal › Article

Antigen Presentation

Monocytes

Ethanol

T-Lymphocytes

Antigens

1994

35 Citations (Scopus)

Acute ethanol consumption synergizes with trauma to increase monocyte tumor necrosis factor α production late postinjury

Szabó, G., Mandrekar, P., Verma, B., Isaac, A. & Catalano, D., Nov 1994, In : Journal of Clinical Immunology. 14, 6, p. 340-352 13 p.

Research output: Contribution to journal › Article

Monocytes

Ethanol

Tumor Necrosis Factor-alpha

Wounds and Injuries

Acetylmuramyl-Alanyl-Isoglutamine

7 Citations (Scopus)

Dibutyryl-cAMP modulation of receptor expression and antigen presentation capacity in monocyte subpopulations

Szabó, G., Kodys, K. & Miller-Graziano, C. L., 1994, In : International Journal of Immunopharmacology. 16, 2, p. 151-162 12 p.

Research output: Contribution to journal › Article

Cyclic AMP Receptors

Antigen Presentation

Antigen-Presenting Cells

Monocytes

IgG Receptors

21 Citations (Scopus)

Regulatory Potential of Ethanol and Retinoic Acid on Human Monocyte Functions

Szabo, G., Puppolo, M., Verma, B. & Catalano, D., 1994, In : Alcoholism: Clinical and Experimental Research. 18, 3, p. 548-554 7 p.

Research output: Contribution to journal › Article

Tretinoin

Monocytes

Ethanol

Transforming Growth Factors

Down-Regulation

1995

94 Citations (Scopus)

Inhibition of superantigen-induced T cell proliferation and monocyte IL-1β, TNF-α, and IL-6 production by acute ethanol treatment

Szabó, G., Mandrekar, P. & Catalano, D., 1995, In : Journal of Leukocyte Biology. 58, 3, p. 342-350 9 p.

Research output: Contribution to journal › Article

Superantigens

Interleukin-1

Monocytes

Interleukin-6

Ethanol

1996

11 Citations (Scopus)

Acute ethanol treatment augments interleukin-12 production in activated human monocytes

Szabó, G., Girouard, L., Mandrekar, P. & Catalano, D., 1996, In : Annals of the New York Academy of Sciences. 795, p. 422-425 4 p.

Research output: Contribution to journal › Article

Interleukin-12

Monocytes

Ethanol

64 Citations (Scopus)

Human monocyte IL-10 production is increased by acute ethanol treatment

Mandrekar, P., Catalano, D., Girouard, L. & Szabó, G., Jul 1996, In : Cytokine. 8, 7, p. 567-577 11 p.

Research output: Contribution to journal › Article

Interleukin-10

Monocytes

Ethanol

Messenger RNA

Cyclooxygenase Inhibitors

14 Citations (Scopus)

NF-κB, a prototypical cytokine-regulated transcription factor: Implications for alcohol-mediated responses

Zakhari, S. & Szabó, G., 1996, In : Alcoholism: Clinical and Experimental Research. 20, 8 SUPPL.

Research output: Contribution to journal › Article

MHC Class II Genes

NF-kappa B

Gene expression

Liver

Alcoholism

160 Citations (Scopus)

Regulation of human monocyte functions by acute ethanol treatment: Decreased tumor necrosis factorα, interleukin-1β and elevated interleukin- 10, and transforming growth factor-β production

Szabó, G., Mandrekar, P., Girouard, L. & Catalane, D., 1996, In : Alcoholism: Clinical and Experimental Research. 20, 5, p. 900-907 8 p.

Research output: Contribution to journal › Article

Transforming Growth Factors

Interleukin-1

Interleukin-10

Monocytes

Ethanol

1997

12 Citations (Scopus)

Alcohol and susceptibility to tuberculosis

Szabó, G., 1997, In : Alcohol Research and Health. 21, 1, p. 39-41 3 p.

Research output: Contribution to journal › Article

Tuberculosis

Alcohols

69 Citations (Scopus)

Alcohol-induced regulation of nuclear regulatory factor-κβ in human monocytes

Mandrekar, P., Catalano, D. & Szabó, G., 1997, In : Alcoholism: Clinical and Experimental Research. 21, 6, p. 988-994 7 p.

Research output: Contribution to journal › Article

Monocytes

Ethanol

Alcohols

Chemical activation

Cytokines

83 Citations (Scopus)

Alcohol's contribution to compromised immunity

Szabó, G., 1997, In : Alcohol Research and Health. 21, 1, p. 30-38 9 p.

Research output: Contribution to journal › Article

Immunity

Alcohols

Alcoholics

Immune System

Somatotypes

1998

53 Citations (Scopus)

Monocytes, alcohol use, and altered immunity

Szabó, G., Aug 1998, In : Alcoholism: Clinical and Experimental Research. 22, 5 SUPPL.

Research output: Contribution to journal › Article

Alcohol Drinking

Monocytes

Immunity

Alcohols

Interferons

14 Citations (Scopus)

Regulation of monocyte IL-12 production: Augmentation by lymphocyte contact and acute ethanol treatment, inhibition by elevated intracellular cAMP

Szabó, G., Girouard, L., Mandrekar, P. & Catalano, D., Nov 4 1998, In : International Journal of Immunopharmacology. 20, 9, p. 491-503 13 p.

Research output: Contribution to journal › Article

Interleukin-12

Monocytes

Ethanol

Lymphocytes

Interleukin-10

37 Citations (Scopus)

Regulation of monocyte interleukin-12 production by acute alcohol: A role for inhibition by interleukin-10

Girouard, L., Mandrekar, P., Catalano, D. & Szabó, G., Feb 1998, In : Alcoholism: Clinical and Experimental Research. 22, 1, p. 211-216 6 p.

Research output: Contribution to journal › Article

Interleukin-12

Interleukin-10

Monocytes

Alcohols

Ethanol

1999

59 Citations (Scopus)

Acute alcohol consumption attenuates interleukin-8 (IL-8) and monocyte chemoattractant peptide-1 (MCP-1) induction in response to ex vivo stimulation

Szabó, G., Chavan, S., Mandrekar, P. & Catalano, D., 1999, In : Journal of Clinical Immunology. 19, 1, p. 67-76 10 p.

Research output: Contribution to journal › Article

Chemotactic Factors

Interleukin-8

Alcohol Drinking

Monocytes

Peptides

338 Citations (Scopus)

Consequences of alcohol consumption on host defence

Szabó, G., 1999, In : Alcohol and Alcoholism. 34, 6, p. 830-841 12 p.

Research output: Contribution to journal › Review article

Alcohol Drinking

Alcohols

Cellular Immunity

Ethanol

T-Lymphocytes

111 Citations (Scopus)

Inhibition of lipopolysaccharide-mediated NFκB activation by ethanol in human monocytes

Mandrekar, P., Catalano, D. & Szabó, G., 1999, In : International Immunology. 11, 11, p. 1781-1790 10 p.

Research output: Contribution to journal › Article

Lipopolysaccharides

Monocytes

Ethanol

Alcohols

Cytokines

16 Citations (Scopus)

Monocytes, alcohol use, and altered immunity

Szabó, G., 1999, In : Alcoholism: Clinical and Experimental Research. 23, 5 SUPPL.

Research output: Contribution to journal › Article

Alcohol Drinking

Monocytes

Immunity

Alcohols

Interferons

2000

14 Citations (Scopus)

Acceptance of an ABO-Incompatible Mismatched (AB⁺ to O⁺) Liver Allograft With the Use of Daclizumab and Mycophenolate Mofetil

Fang, W. C., Saltzman, J., Rososhansky, S., Szabó, G., Heard, S. O., Banner, B., Chari, R. & Katz, E., 2000, In : Liver Transplantation. 6, 4, p. 497-500 4 p.

Research output: Contribution to journal › Article

Mycophenolic Acid

Muromonab-CD3

Allografts

Alprostadil

Liver

15 Citations (Scopus)

Management of recurrent hepatitis C after liver transplantation: A concise review

Szabó, G., Katz, E. & Bonkovsky, H. L., 2000, In : American Journal of Gastroenterology. 95, 9, p. 2164-2170 7 p.

Research output: Contribution to journal › Review article

Hepatitis C

Liver Transplantation

Ribavirin

Transplants

Therapeutics

12 Citations (Scopus)

New insights into the molecular mechanisms of alcoholic hepatitis: A potential role for NF-κB activation?

Szabó, G., 2000, In : Journal of Laboratory and Clinical Medicine. 135, 5, p. 367-369 3 p.

Research output: Contribution to journal › Editorial

Alcoholic Hepatitis

2001

19 Citations (Scopus)

Interferon α and alcohol augment nuclear regulatory factor-κB activation in HepG2 cells, and interferon α increases pro-inflammatory cytokine production

Szabó, G., Catalano, D., Bellerose, G. & Mandrekar, P., 2001, In : Alcoholism: Clinical and Experimental Research. 25, 8, p. 1188-1197 10 p.

Research output: Contribution to journal › Article

Hep G2 Cells

Interferons

Ethanol

Chemical activation

Alcohols

72 Citations (Scopus)

Reduced alloreactive T-cell activation after alcohol intake is due to impaired monocyte accessory cell function and correlates with elevated IL-10, IL-13, and decreased IFNγ levels

Szabó, G., Mandrekar, P., Dolganiuc, A., Catalano, D. & Kodys, K., 2001, In : Alcoholism: Clinical and Experimental Research. 25, 12, p. 1766-1772 7 p.

Research output: Contribution to journal › Article

T-cells

Interleukin-13

Accessories

Interleukin-10

Monocytes

92 Citations (Scopus)

Tacrolimus and cyclosporine A inhibit allostimulatory capacity and cytokine production of human myeloid dendritic cells

Szabó, G., Gavala, C. & Mandrekar, P., 2001, In : Journal of Investigative Medicine. 49, 5, p. 442-449 8 p.

Research output: Contribution to journal › Article

Tacrolimus

Myeloid Cells

Dendritic Cells

Cyclosporine

Cytokines

2002

48 Citations (Scopus)

Acute alcohol inhibits the induction of nuclear regulatory factor κB activation through CD14/Toll- like receptor 4, interleukin-1, and tumor necrosis factor receptors: A common mechanism independent of inhibitory κbα degradation?

Mandrekar, P., Dolganiuc, A., Bellerose, G., Kodys, K., Romics, L., Nizamani, R. & Szabó, G., Nov 1 2002, In : Alcoholism: Clinical and Experimental Research. 26, 11, p. 1609-1614 6 p.

Research output: Contribution to journal › Article

Toll-Like Receptor 4

Tumor Necrosis Factor Receptors

Interleukin-1

Chemical activation

Alcohols

17 Citations (Scopus)

Ethanol-mediated regulation of transcription factors in immunocompetent cells.

Szabó, G. & Mandrekar, P., 2002, In : Frontiers in bioscience : a journal and virtual library. 7

Research output: Contribution to journal › Article

NF-kappa B

Ethanol

Transcription Factors

Chemical activation

Alcohols

15 Citations (Scopus)

FcγR cross-linking mediates NF-κB activation, reduced antigen presentation capacity, and decreased IL-12 production in monocytes without modulation of myeloid dendritic cell development

Drechsler, Y., Chavan, S., Catalano, D., Mandrekar, P. & Szabó, G., Oct 1 2002, In : Journal of Leukocyte Biology. 72, 4, p. 657-667 11 p.

Research output: Contribution to journal › Article

Antigen Presentation

Myeloid Cells

Interleukin-12

Dendritic Cells

Monocytes

16 Citations (Scopus)

Inhibition of NF-κB binding correlates with increased nuclear glucocorticoid receptor levels in acute alcohol-treated human monocytes

Mandrekar, P., Bellerose, G. & Szabó, G., Dec 1 2002, In : Alcoholism: Clinical and Experimental Research. 26, 12, p. 1872-1879 8 p.

Research output: Contribution to journal › Article

Glucocorticoid Receptors

Cytoplasmic and Nuclear Receptors

Monocytes

Alcohols

Response Elements

111 Citations (Scopus)

Liver in sepsis and systemic inflammatory response syndrome

Szabó, G., Romics, L. & Frendl, G., Nov 2002, In : Clinics in Liver Disease. 6, 4, p. 1045-1066 22 p.

Research output: Contribution to journal › Review article

Systemic Inflammatory Response Syndrome

Sepsis

Liver

Macrophages

Kupffer Cells

7 Citations (Scopus)

Modulation of immunity and viral-host interactions by alcohol

Thiele, G. M., Szabó, G., Kovacs, E. J., Bautista, A. P., Sosa, L. & Jerrells, T. R., Dec 1 2002, In : Alcoholism: Clinical and Experimental Research. 26, 12, p. 1897-1908 12 p.

Research output: Contribution to journal › Article

Immunity

Ethanol

Alcohols

Modulation

Chemokines

On the credibility of 'credibility of problem-solving therapy and medication for the treatment of depression among primary care patients' by Thornett A, Mynors-Wallis L [4] (multiple letters)

Bense, L., Szabó, G., Thornett, A. M. & Mynors-Wallis, L., 2002, In : Medical Science Monitor. 8, 6

Research output: Contribution to journal › Article

Physicians' Practice Patterns

Psychotherapy

Antidepressive Agents

Primary Health Care

Depression

54 Citations (Scopus)

Severe cholestatic hepatitis caused by thiazolidinediones: Risks associated with substituting rosiglitazone for troglitazone

Bonkovsky, H. L., Azar, R., Bird, S., Szabó, G. & Banner, B., 2002, In : Digestive Diseases and Sciences. 47, 7, p. 1632-1637 6 p.

Research output: Contribution to journal › Article

rosiglitazone

troglitazone

Thiazolidinediones

Hepatitis

Alkaline Phosphatase

2003

51 Citations (Scopus)

Additive inhibition of dendritic cell allostimulatory capacity by alcohol and hepatitis C is not restored by DC maturation and involves abnormal IL-10 and IL-2 induction

Dolganiuc, A., Kodys, K., Kopasz, A., Marshall, C., Mandrekar, P. & Szabó, G., Jun 1 2003, In : Alcoholism: Clinical and Experimental Research. 27, 6, p. 1023-1031 9 p.

Research output: Contribution to journal › Article

Hepatitis C

Interleukin-10

Dendritic Cells

Viruses

Interleukin-2

2 Citations (Scopus)

A máj sejtszintú és molekuláris eltérései szepszisben és szisztémás gyulladásos válaszreakció (SIRS) szindrómában.

Translated title of the contribution: Cellular and molecular changes of the liver in sepsis and in systemic inflammatory response syndrome (SIRS)Romics, L., Frendl, G. & Szabó, G., Mar 16 2003, In : Orvosi Hetilap. 144, 11, p. 499-506 8 p.

Research output: Contribution to journal › Review article

Systemic Inflammatory Response Syndrome

Sepsis

Liver

Acute-Phase Proteins

Toll-Like Receptors

Erratum: Additive inhibition of dendritic cell allostimulatory capacity by alcohol and hepatitis C is not restored by DC maturation and involves abnormal IL-10 and IL-2 induction (Alcoholism: Clinical and Experimental Research (June 2003) 27 (1023-1031))

Dolganiuc, A., Kodys, K., Kopasz, A., Marshall, C., Mandrekar, P. & Szabó, G., Jul 1 2003, In : Alcoholism: Clinical and Experimental Research. 27, 7, p. 1212 1 p.

Research output: Contribution to journal › Comment/debate

Hepatitis C

Interleukin-10

Dendritic Cells

Alcoholism

Interleukin-2

224 Citations (Scopus)

Hepatitis C virus core and nonstructural protein 3 proteins induce pro- and anti-inflammatory cytokines and inhibit dendritic cell differentiation

Dolganiuc, A., Kodys, K., Kopasz, A., Marshall, C., Do, T., Romics, L., Mandrekar, P., Zapp, M. & Szabó, G., Jun 1 2003, In : Journal of Immunology. 170, 11, p. 5615-5624 10 p.

Research output: Contribution to journal › Article

Dendritic Cells

Hepacivirus

Cell Differentiation

Anti-Inflammatory Agents

Cytokines