• 1170 Citations
  • 22 h-Index
1989 …2019

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

  • 1170 Citations
  • 22 h-Index
  • 44 Article
  • 6 Review article
  • 3 Letter
  • 2 Short survey
2019

Extracellular vesicles in modifying the effects of ionizing radiation

Szatmári, T., Hargitai, R., Sáfrány, G. & Lumniczky, K., Nov 2019, In : International journal of molecular sciences. 20, 22, 5527.

Research output: Contribution to journalReview article

Open Access
1 Citation (Scopus)

Radio-detoxified LPS alters bone marrow-derived extracellular vesicles and endothelial progenitor cells

Hegyesi, H., Sándor, N., Sáfrány, G., Lovas, V., Kovács, Á., Takács, A., Kohidai, L., Turiák, L., Kittel, Á., Pálóczi, K., Bertók, L. & Buzás, E. I., Oct 29 2019, In : Stem Cell Research and Therapy. 10, 1, 313.

Research output: Contribution to journalArticle

Open Access

Radiotherapy-induced changes in the systemic immune and inflammation parameters of head and neck cancer patients

Balázs, K., Kis, E., Badie, C., Bogdándi, E. N., Candéias, S., Garcia, L. C., Dominczyk, I., Frey, B., Gaipl, U., Jurányi, Z., Kocsis, Z. S., Rutten, E. A., Sáfrány, G., Widlak, P. & Lumniczky, K., Sep 2019, In : Cancers. 11, 9, 1324.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)
2018

Extracellular vesicles mediate low dose ionizing radiation-induced immune and inflammatory responses in the blood

Szatmári, T., Persa, E., Kis, E., Benedek, A., Hargitai, R., Sáfrány, G. & Lumniczky, K., Mar 29 2018, (Accepted/In press) In : International Journal of Radiation Biology. p. 1-11 11 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

In vivo irradiation of mice induces activation of dendritic cells

Persa, E., Szatmári, T., Sáfrány, G. & Lumniczky, K., Aug 14 2018, In : International Journal of Molecular Sciences. 19, 8, 2391.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2017

Extracellular vesicles mediate radiation-induced systemic bystander signals in the bone marrow and spleen

Szatmári, T., Kis, D., Bogdándi, E. N., Benedek, A., Bright, S., Bowler, D., Persa, E., Kis, E., Balogh, A., Naszályi, L. N., Kadhim, M., Sáfrány, G. & Lumniczky, K., Mar 27 2017, In : Frontiers in Immunology. 8, MAR, 347.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Ionizing radiation-induced immune and inflammatory reactions in the brain

Lumniczky, K., Szatmári, T. & Sáfrány, G., May 5 2017, In : Frontiers in Immunology. 8, MAY, 517.

Research output: Contribution to journalReview article

26 Citations (Scopus)
2016

Age-related effects of X-ray irradiation on mouse hippocampus

Casciati, A., Dobos, K., Antonelli, F., Benedek, A., Kempf, S. J., Bellés, M., Balogh, A., Tanori, M., Heredia, L., Atkinson, M. J., von Toerne, C., Azimzadeh, O., Saran, A., Sáfrány, G., Benotmane, M. A., Linares-Vidal, M. V., Tapio, S., Lumniczky, K. & Pazzaglia, S., May 10 2016, In : Oncotarget. 7, 19, p. 28040-28058 19 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

A sugárterápia hatása a daganatellenes immunválaszra

Translated title of the contribution: The effect of radiotherapy on the antitumor immune response. Possibilities to combine radiotherapy with immunotherapyLumniczky, K. & Sáfrány, G., Mar 2 2016, In : Magyar onkologia. 60, 1, p. 46-54 9 p.

Research output: Contribution to journalReview article

2 Citations (Scopus)
2015

Growth Differentiation Factor-15 (GDF-15) is a potential marker of radiation response and radiation sensitivity

Sándor, N., Schilling-Tóth, B., Kis, E., Benedek, A., Lumniczky, K., Sáfrány, G. & Hegyesi, H., Nov 1 2015, In : Mutation Research - Genetic Toxicology and Environmental Mutagenesis. 793, p. 142-149 8 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

The effect of ionizing radiation on regulatory T cells in health and disease

Persa, E., Balogh, A., Sáfrány, G. & Lumniczky, K., Nov 28 2015, In : Cancer Letters. 368, 2, p. 252-261 10 p.

Research output: Contribution to journalShort survey

37 Citations (Scopus)

The impact of radiation therapy on the antitumor immunity: Local effects and systemic consequences

Lumniczky, K. & Sáfrány, G., Jan 1 2015, In : Cancer Letters. 356, 1, p. 114-125 12 p.

Research output: Contribution to journalShort survey

37 Citations (Scopus)

TP53inp1 gene is implicated in early radiation response in human fibroblast cells

Sándor, N., Schilling-Tóth, B., Kis, E., Fodor, L., Mucsányi, F., Sáfrány, G. & Hegyesi, H., Oct 23 2015, In : International journal of molecular sciences. 16, 10, p. 25450-25465 16 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
2014

Low dose cranial irradiation-induced cerebrovascular damage is reversible in mice

Sandor, N., Walter, F. R., Bocsik, A., Sántha, P., Schilling-Tóth, B., Lener, V., Varga, Z., Kahán, Z., Deli, M. A., Sáfrány, G. & Hegyesi, H., Nov 13 2014, In : PloS one. 9, 11, e112397.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Role of GDF15 in radiosensitivity of breast cancer cells

Schilling-Tóth, B., Sándor, N., Walter, F. R., Bocsik, A., Sáfrány, G. & Hegyesi, H., Oct 2014, In : Central European Journal of Biology. 9, 10, p. 982-992 11 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2013

The effect of ionizing radiation on the homeostasis and functional integrity of murine splenic regulatory T cells

Balogh, A., Persa, E., Bogdándi, E. N., Benedek, A., Hegyesi, H., Sáfrány, G. & Lumniczky, K., Feb 1 2013, In : Inflammation Research. 62, 2, p. 201-212 12 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)
2012

A laboratory inter-comparison of the importance of serum serotonin levels in the measurement of a range of radiation-induced bystander effects: Overview of study and results presentation

Mothersill, C., Antonelli, F., Dahle, J., Dini, V., Hegyesi, H., Iliakis, G., Kämäräinen, K., Launonen, V., Lumniczky, K., Lyng, F., Safrany, G., Salomaa, S., Schilling-Tóth, B., Tabocchini, A. & Kadhim, M. A., Oct 1 2012, In : International Journal of Radiation Biology. 88, 10, p. 763-769 7 p.

Research output: Contribution to journalReview article

7 Citations (Scopus)

Structural analysis of oval-cell-mediated liver regeneration in rats

Dezso, K., Papp, V., Bugyik, E., Hegyesi, H., Sáfrány, G., Bödör, C., Nagy, P. & Paku, S., Oct 1 2012, In : Hepatology. 56, 4, p. 1457-1467 11 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)
2011
27 Citations (Scopus)
2010

Effects of low-dose radiation on the immune system of mice after total-body irradiation

Bogdándi, E. N., Balogh, A., Felgyinszki, N., Szatmári, T., Persa, E., Hildebrandt, G., Sáfrány, G. & Lumniczky, K., Oct 2010, In : Radiation Research. 174, 4, p. 480-489 10 p.

Research output: Contribution to journalArticle

71 Citations (Scopus)
2009

Bcl-2 or bcl-XL gene therapy increases neural plasticity proteins nestin and c-fos expression in PC12 cells

Gal, A., Pentelenyi, K., Remenyi, V., Wappler, E. A., Safrany, G., Skopal, J. & Nagy, Z., Sep 1 2009, In : Neurochemistry international. 55, 5, p. 349-353 5 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
2008
12 Citations (Scopus)

Bcl-2 or Bcl-XL gene therapy reduces apoptosis and increases plasticity protein GAP-43 in PC12 cells

Gal, A., Szilagyi, G., Wappler, E., Safrany, G. & Nagy, Z., Jul 1 2008, In : Brain Research Bulletin. 76, 4, p. 349-353 5 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Triiodothyronine accelerates differentiation of rat liver progenitor cells into hepatocytes

László, V., Dezső, K., Baghy, K., Papp, V., Kovalszky, I., Sáfrány, G., Thorgeirsson, S. S., Nagy, P. & Paku, S., Nov 2008, In : Histochemistry and Cell Biology. 130, 5, p. 1005-1014 10 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)
2006

Cancer gene therapy: Combination with radiation therapy and the role of bystander cell killing in the anti-tumor effect

Lumniczky, K. & Sáfrány, G., Aug 15 2006, In : Pathology and Oncology Research. 12, 2, p. 118-124 7 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)

Detailed characterization of the mouse glioma 261 tumor model for experimental glioblastoma therapy

Szatmári, T., Lumniczky, K., Désaknai, S., Trajcevski, S., Hídvégi, E. J., Hamada, H. & Sáfrány, G., Jun 1 2006, In : Cancer Science. 97, 6, p. 546-553 8 p.

Research output: Contribution to journalArticle

147 Citations (Scopus)

Microarray analysis of radiation response genes in primary human fibroblasts

Kis, E., Szatmári, T., Keszei, M., Farkas, R., Ésik, O., Lumniczky, K., Falus, A. & Sáfrány, G., Dec 1 2006, In : International Journal of Radiation Oncology Biology Physics. 66, 5, p. 1506-1514 9 p.

Research output: Contribution to journalArticle

85 Citations (Scopus)

Tumor radiosensitizers - Current status of development of various approaches: Report of an International Atomic Energy Agency meeting

Horsman, M. R., Bohm, L., Margison, G. P., Milas, L., Rosier, J. F., Safrany, G., Selzer, E., Verheij, M. & Hendry, J. H., Feb 1 2006, In : International Journal of Radiation Oncology Biology Physics. 64, 2, p. 551-561 11 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)
2005
28 Citations (Scopus)
2004

Can interstitial brachytherapy compete with external beam radiotherapy in breast cancer? in response to Drs. Polgár, Major, Strnad, Inoue, and Guedea [2]

Ésik, O., Póti, Z., Nemeskéri, C., Mayer, Á., Szalai, G., Sáfrány, G., Trón, L., Antal, G., Glavák, C. & Repa, I., Sep 1 2004, In : International Journal of Radiation Oncology Biology Physics. 60, 1, p. 343-345 3 p.

Research output: Contribution to journalLetter

Characteristics of radiogenic lower motor neurone disease, a possible link with a preceding viral infection

Ésik, O., Vönöczky, K., Lengyel, Z., Sáfrány, G. & Trón, L., Feb 1 2004, In : Spinal Cord. 42, 2, p. 99-105 7 p.

Research output: Contribution to journalReview article

7 Citations (Scopus)

Partial breast irradiation with interstitial 60CO brachytherapy results in frequent grade 3 or 4 toxicity. Evidence based on a 12-year follow-up of 70 patients

Póti, Z., Nemeskéri, C., Fekésházy, A., Sáfrány, G., Bajzik, G., Nagy, Z. P., Bidlek, M., Sinkovics, I., Udvarhelyi, N., Liszkay, G., Repa, I., Galuska, L., Trón, L., Mayer, Á. & Ésik, O., Mar 15 2004, In : International Journal of Radiation Oncology Biology Physics. 58, 4, p. 1022-1033 12 p.

Research output: Contribution to journalArticle

47 Citations (Scopus)

PET Identifies Transitional Metabolic Change in the Spinal Coral Following a Subthreshold Dose of Irradiation

Ésik, O., Emri, M., Szakáll, S., Herzog, H., Sáfrány, G., Lengyel, E., Boér, A., Liszkay, G., Trón, L., Lengyel, Z. & Repa, I., Jan 1 2004, In : Pathology and Oncology Research. 10, 1, p. 42-46 5 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)
2003
37 Citations (Scopus)

A review on radiogenic Lhermitte's sign

Ésik, O., Csere, T., Stefanits, K., Lengyel, Z., Sáfrány, G., Vönöczky, K., Lengyel, E., Nemeskéri, C., Repa, I. & Trón, L., Jan 1 2003, In : Pathology and Oncology Research. 9, 2, p. 115-120 6 p.

Research output: Contribution to journalReview article

33 Citations (Scopus)

Increased metabolic activity in the spinal cord of patients with long-standing Lhermitte's sign

Ésik, O., Csere, T., Stefanits, K., Szakáll, S., Lengyel, Z., Sáfrány, G., Vönöczky, K., Lengyel, E., Olajos, J., Bajzik, G. & Trón, L., Oct 1 2003, In : Strahlentherapie und Onkologie. 179, 10, p. 690-693 4 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Local tumour irradiation enhances the anti-tumour effect of a double-suicide gene therapy system in a murine glioma model

Desaknai, S., Lumniczky, K., Esik, O., Hamada, H. & Safrany, G., May 1 2003, In : Journal of Gene Medicine. 5, 5, p. 377-385 9 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)
2002

A PET study on the characterization of partially reversible radiogenic lower motor neurone disease

Ésik, O., Lengyel, Z., Sáfrány, G., Vönöczky, K., Ágoston, P., Székely, J., Lengyel, E., Márián, T., Trón, L. & Bodrogi, I., Jan 1 2002, In : Spinal Cord. 40, 9, p. 468-473 6 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Local tumor irradiation augments the antitumor effect of cytokine-producing autologous cancer cell vaccines in a murine glioma model

Lumniczky, K., Desaknai, S., Mangel, L., Szende, B., Hamada, H., Hidvegi, E. J. & Sáfrány, G., Jan 1 2002, In : Cancer Gene Therapy. 9, 1, p. 44-52 9 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)

Oncogenes and tumor suppressor genes in murine tumors induced by neutron- or gamma-irradiation in utero

Antal, S., Lumniczky, K., Pálfalvi, J., Hidvégi, E., Schneider, F. & Sáfrány, G., Jul 1 2002, In : International Congress Series. 1236, C, p. 119-122 4 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2001

Apoptotic and mitotic activity in squamous cell carcinoma cells after combined modality treatment with γ-irradiation and dibromodulcitol

Kraxner, H., Tamás, L., Sáfrány, G., Ribári, O., Oláh, I., Hidvégi, E., Répássy, G. & Szende, B., Jan 1 2001, In : Cell biology international. 25, 7, p. 599-606 8 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Brain tumor treatment with IL-2 and IL-12 producing autologous cancer cell vaccines

Desaknai, S., Lumniczky, K., Hidvegi, E. J., Hamada, H. & Safrany, G., Jan 1 2001, In : Advances in experimental medicine and biology. 495, p. 369-372 4 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
1998

Carcinogenic alterations in murine liver, lung, and uterine tumors induced by in utero exposure to ionizing radiation

Lumniczky, K., Antal, S., Unger, E., Wunderlich, L., Hidvégi, E. J. & Sáfrány, G., Mar 31 1998, In : Molecular Carcinogenesis. 21, 2, p. 100-110 11 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)
1997

Oncogenic changes in murine lymphoid tumors induced by in utero exposure to ionizing radiation

Lumniczky, K., Antal, S., Unger, E., Hidvégi, E. J. & Sáfrány, G., Sep 6 1997, In : Radiation Oncology Investigations. 5, 3, p. 158-162 5 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Simultaneous isolation of both RNA and DNA from many small tissue samples

Lumniczky, K. & Sáfrány, G., Dec 1 1997, In : Acta biologica Hungarica. 48, 2, p. 253-257 5 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
1995
41 Citations (Scopus)
1993
Open Access
31 Citations (Scopus)

Transcription factor RFX1 helps control the promoter of the mouse ribosomal protein-encoding gene rpL30 by binding to its α element

Sáfrány, G. & Perry, R. P., Oct 15 1993, In : Gene. 132, 2, p. 279-283 5 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)